Improving selectivity in multimodal chromatography using controlled pH gradient elution

Journal of Chromatography A

Volumn 1233, Issue , 2012, Pages 152-155

  Holstein, Melissa A ^a   Nikfetrat, Amir A M ^a   Gage, Mark ^a   Hirsh, Allen G ^b   Cramer, Steven M ^a  

^a RENSSELAER POLYTECHNIC INSTITUTE   (United States)

^b CryoBioPhysica Inc   (United States)

Author keywords

Multimodal chromatography; PH gradient; Protein separations; Selectivity

Indexed keywords

CATION EXCHANGES; CHROMATOGRAPHIC RESINS; FUTURE APPLICATIONS; MODEL PROTEINS; MULTI-MODAL; MULTIPLE INTERACTIONS; PH GRADIENT; PH GRADIENT ELUTION; PH GRADIENTS; PROOF OF CONCEPT; PROTEIN MIXTURES; PROTEIN SEPARATIONS; SALT GRADIENT;

CATALYST SELECTIVITY; PH; PROTEINS; RESINS;

CHROMATOGRAPHY;

ALPHA LACTALBUMIN; BETA LACTOGLOBULIN; RESIN; SODIUM CHLORIDE; TRYPSIN INHIBITOR;

ANALYTICAL PARAMETERS; ARTICLE; CHROMATOGRAPHY; CONTROLLED STUDY; ELUTION; ION EXCHANGE CHROMATOGRAPHY; MOLECULAR INTERACTION; MULTIMODAL CHROMATOGRAPHY; PH; PH GRADIENT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; SELECTIVITY; SURFACE CHARGE;

CATION EXCHANGE RESINS; CHROMATOGRAPHY, ION EXCHANGE; HYDROGEN-ION CONCENTRATION;

EID: 84858623664     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2012.01.074     Document Type: Article

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