-
1
-
-
81555216077
-
Gene expression profiling in breast cancer: classification, prognostication, and prediction
-
10.1016/S0140-6736(11)61539-0, 22098854
-
Reis-Filho JS, Pusztai L. Gene expression profiling in breast cancer: classification, prognostication, and prediction. Lancet 2011, 378:1812-1823. 10.1016/S0140-6736(11)61539-0, 22098854.
-
(2011)
Lancet
, vol.378
, pp. 1812-1823
-
-
Reis-Filho, J.S.1
Pusztai, L.2
-
2
-
-
60849097255
-
Gene-expression signatures in breast cancer
-
10.1056/NEJMra0801289, 19228622
-
Sotiriou C, Pusztai L. Gene-expression signatures in breast cancer. N Engl J Med 2009, 360:790-800. 10.1056/NEJMra0801289, 19228622.
-
(2009)
N Engl J Med
, vol.360
, pp. 790-800
-
-
Sotiriou, C.1
Pusztai, L.2
-
3
-
-
73949136029
-
The contribution of gene expression profiling to breast cancer classification, prognostication and prediction: a retrospective of the last decade
-
Weigelt B, Baehner FL, Reis-Filho JS. The contribution of gene expression profiling to breast cancer classification, prognostication and prediction: a retrospective of the last decade. J Pathol 2010, 220:263-280.
-
(2010)
J Pathol
, vol.220
, pp. 263-280
-
-
Weigelt, B.1
Baehner, F.L.2
Reis-Filho, J.S.3
-
4
-
-
81555199640
-
Microarrays in the 2010s: the contribution of microarray-based gene expression profiling to breast cancer classification, prognostication and prediction
-
10.1186/bcr2890, 3218943, 21787441
-
Colombo PE, Milanezi F, Weigelt B, Reis-Filho JS. Microarrays in the 2010s: the contribution of microarray-based gene expression profiling to breast cancer classification, prognostication and prediction. Breast Cancer Res 2011, 13:212. 10.1186/bcr2890, 3218943, 21787441.
-
(2011)
Breast Cancer Res
, vol.13
, pp. 212
-
-
Colombo, P.E.1
Milanezi, F.2
Weigelt, B.3
Reis-Filho, J.S.4
-
5
-
-
79551710060
-
Gene pathways associated with prognosis and chemotherapy sensitivity in molecular subtypes of breast cancer
-
10.1093/jnci/djq524, 21191116
-
Iwamoto T, Bianchini G, Booser D, Qi Y, Coutant C, Shiang CY, Santarpia L, Matsuoka J, Hortobagyi GN, Symmans WF, Holmes FA, O'Shaughnessy J, Hellerstedt B, Pippen J, Andre F, Simon R, Pusztai L. Gene pathways associated with prognosis and chemotherapy sensitivity in molecular subtypes of breast cancer. J Natl Cancer Inst 2011, 103:264-272. 10.1093/jnci/djq524, 21191116.
-
(2011)
J Natl Cancer Inst
, vol.103
, pp. 264-272
-
-
Iwamoto, T.1
Bianchini, G.2
Booser, D.3
Qi, Y.4
Coutant, C.5
Shiang, C.Y.6
Santarpia, L.7
Matsuoka, J.8
Hortobagyi, G.N.9
Symmans, W.F.10
Holmes, F.A.11
O'Shaughnessy, J.12
Hellerstedt, B.13
Pippen, J.14
Andre, F.15
Simon, R.16
Pusztai, L.17
-
6
-
-
84655161546
-
Challenges translating breast cancer gene signatures into the clinic
-
10.1038/nrclinonc.2011.125, 21878891
-
Weigelt B, Pusztai L, Ashworth A, Reis-Filho JS. Challenges translating breast cancer gene signatures into the clinic. Nat Rev Clin Oncol 2011, 9:58-64. 10.1038/nrclinonc.2011.125, 21878891.
-
(2011)
Nat Rev Clin Oncol
, vol.9
, pp. 58-64
-
-
Weigelt, B.1
Pusztai, L.2
Ashworth, A.3
Reis-Filho, J.S.4
-
7
-
-
78149477701
-
Genomic subtypes of breast cancer identified by array-comparative genomic hybridization display distinct molecular and clinical characteristics
-
10.1186/bcr2596, 2917037, 20576095
-
Jonsson G, Staaf J, Vallon-Christersson J, Ringner M, Holm K, Hegardt C, Gunnarsson H, Fagerholm R, Strand C, Agnarsson BA, Kilpivaara O, Luts L, Heikkila P, Aittomaki K, Blomqvist C, Loman N, Malmstrom P, Olsson H, Johannsson OT, Arason A, Nevanlinna H, Barkardottir RB, Borg A. Genomic subtypes of breast cancer identified by array-comparative genomic hybridization display distinct molecular and clinical characteristics. Breast Cancer Res 2010, 12:R42. 10.1186/bcr2596, 2917037, 20576095.
-
(2010)
Breast Cancer Res
, vol.12
-
-
Jonsson, G.1
Staaf, J.2
Vallon-Christersson, J.3
Ringner, M.4
Holm, K.5
Hegardt, C.6
Gunnarsson, H.7
Fagerholm, R.8
Strand, C.9
Agnarsson, B.A.10
Kilpivaara, O.11
Luts, L.12
Heikkila, P.13
Aittomaki, K.14
Blomqvist, C.15
Loman, N.16
Malmstrom, P.17
Olsson, H.18
Johannsson, O.T.19
Arason, A.20
Nevanlinna, H.21
Barkardottir, R.B.22
Borg, A.23
more..
-
8
-
-
72949119310
-
Complex landscapes of somatic rearrangement in human breast cancer genomes
-
10.1038/nature08645, 20033038
-
Stephens PJ, McBride DJ, Lin ML, Varela I, Pleasance ED, Simpson JT, Stebbings LA, Leroy C, Edkins S, Mudie LJ, Greenman CD, Jia M, Latimer C, Teague JW, Lau KW, Burton J, Quail MA, Swerdlow H, Churcher C, Natrajan R, Sieuwerts AM, Martens JW, Silver DP, Langerod A, Russnes HE, Foekens JA, Reis-Filho JS, van 't Veer L, Richardson AL, Borresen-Dale AL, et al. Complex landscapes of somatic rearrangement in human breast cancer genomes. Nature 2009, 462:1005-1010. 10.1038/nature08645, 20033038.
-
(2009)
Nature
, vol.462
, pp. 1005-1010
-
-
Stephens, P.J.1
McBride, D.J.2
Lin, M.L.3
Varela, I.4
Pleasance, E.D.5
Simpson, J.T.6
Stebbings, L.A.7
Leroy, C.8
Edkins, S.9
Mudie, L.J.10
Greenman, C.D.11
Jia, M.12
Latimer, C.13
Teague, J.W.14
Lau, K.W.15
Burton, J.16
Quail, M.A.17
Swerdlow, H.18
Churcher, C.19
Natrajan, R.20
Sieuwerts, A.M.21
Martens, J.W.22
Silver, D.P.23
Langerod, A.24
Russnes, H.E.25
Foekens, J.A.26
Reis-Filho, J.S.27
van 't Veer, L.28
Richardson, A.L.29
Borresen-Dale, A.L.30
more..
-
9
-
-
65249138229
-
Tiling path genomic profiling of grade 3 invasive ductal breast cancers
-
10.1158/1078-0432.CCR-08-1878, 19318498
-
Natrajan R, Lambros MB, Rodriguez-Pinilla SM, Moreno-Bueno G, Tan DS, Marchio C, Vatcheva R, Rayter S, Mahler-Araujo B, Fulford LG, Hungermann D, Mackay A, Grigoriadis A, Fenwick K, Tamber N, Hardisson D, Tutt A, Palacios J, Lord CJ, Buerger H, Ashworth A, Reis-Filho JS. Tiling path genomic profiling of grade 3 invasive ductal breast cancers. Clin Cancer Res 2009, 15:2711-2722. 10.1158/1078-0432.CCR-08-1878, 19318498.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 2711-2722
-
-
Natrajan, R.1
Lambros, M.B.2
Rodriguez-Pinilla, S.M.3
Moreno-Bueno, G.4
Tan, D.S.5
Marchio, C.6
Vatcheva, R.7
Rayter, S.8
Mahler-Araujo, B.9
Fulford, L.G.10
Hungermann, D.11
Mackay, A.12
Grigoriadis, A.13
Fenwick, K.14
Tamber, N.15
Hardisson, D.16
Tutt, A.17
Palacios, J.18
Lord, C.J.19
Buerger, H.20
Ashworth, A.21
Reis-Filho, J.S.22
more..
-
10
-
-
33845331706
-
FGFR1 emerges as a potential therapeutic target for lobular breast carcinomas
-
10.1158/1078-0432.CCR-06-1164, 17121884
-
Reis-Filho JS, Simpson PT, Turner NC, Lambros MB, Jones C, Mackay A, Grigoriadis A, Sarrio D, Savage K, Dexter T, Iravani M, Fenwick K, Weber B, Hardisson D, Schmitt FC, Palacios J, Lakhani SR, Ashworth A. FGFR1 emerges as a potential therapeutic target for lobular breast carcinomas. Clin Cancer Res 2006, 12:6652-6662. 10.1158/1078-0432.CCR-06-1164, 17121884.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 6652-6662
-
-
Reis-Filho, J.S.1
Simpson, P.T.2
Turner, N.C.3
Lambros, M.B.4
Jones, C.5
Mackay, A.6
Grigoriadis, A.7
Sarrio, D.8
Savage, K.9
Dexter, T.10
Iravani, M.11
Fenwick, K.12
Weber, B.13
Hardisson, D.14
Schmitt, F.C.15
Palacios, J.16
Lakhani, S.R.17
Ashworth, A.18
-
11
-
-
52049083886
-
Characterization of the recurrent 8p11-12 amplicon identifies PPAPDC1B, a phosphatase protein, as a new therapeutic target in breast cancer
-
10.1158/0008-5472.CAN-08-1360, 18757432
-
Bernard-Pierrot I, Gruel N, Stransky N, Vincent-Salomon A, Reyal F, Raynal V, Vallot C, Pierron G, Radvanyi F, Delattre O. Characterization of the recurrent 8p11-12 amplicon identifies PPAPDC1B, a phosphatase protein, as a new therapeutic target in breast cancer. Cancer Res 2008, 68:7165-7175. 10.1158/0008-5472.CAN-08-1360, 18757432.
-
(2008)
Cancer Res
, vol.68
, pp. 7165-7175
-
-
Bernard-Pierrot, I.1
Gruel, N.2
Stransky, N.3
Vincent-Salomon, A.4
Reyal, F.5
Raynal, V.6
Vallot, C.7
Pierron, G.8
Radvanyi, F.9
Delattre, O.10
-
12
-
-
76349105055
-
Focal amplification and oncogene dependency of GAB2 in breast cancer
-
10.1038/onc.2009.364, 19881546
-
Bocanegra M, Bergamaschi A, Kim YH, Miller MA, Rajput AB, Kao J, Langerod A, Han W, Noh DY, Jeffrey SS, Huntsman DG, Borresen-Dale AL, Pollack JR. Focal amplification and oncogene dependency of GAB2 in breast cancer. Oncogene 2010, 29:774-779. 10.1038/onc.2009.364, 19881546.
-
(2010)
Oncogene
, vol.29
, pp. 774-779
-
-
Bocanegra, M.1
Bergamaschi, A.2
Kim, Y.H.3
Miller, M.A.4
Rajput, A.B.5
Kao, J.6
Langerod, A.7
Han, W.8
Noh, D.Y.9
Jeffrey, S.S.10
Huntsman, D.G.11
Borresen-Dale, A.L.12
Pollack, J.R.13
-
13
-
-
59449094654
-
Molecular characterization of breast cancer with high-resolution oligonucleotide comparative genomic hybridization array
-
10.1158/1078-0432.CCR-08-1791, 19147748
-
Andre F, Job B, Dessen P, Tordai A, Michiels S, Liedtke C, Richon C, Yan K, Wang B, Vassal G, Delaloge S, Hortobagyi GN, Symmans WF, Lazar V, Pusztai L. Molecular characterization of breast cancer with high-resolution oligonucleotide comparative genomic hybridization array. Clin Cancer Res 2009, 15:441-451. 10.1158/1078-0432.CCR-08-1791, 19147748.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 441-451
-
-
Andre, F.1
Job, B.2
Dessen, P.3
Tordai, A.4
Michiels, S.5
Liedtke, C.6
Richon, C.7
Yan, K.8
Wang, B.9
Vassal, G.10
Delaloge, S.11
Hortobagyi, G.N.12
Symmans, W.F.13
Lazar, V.14
Pusztai, L.15
-
14
-
-
33845191779
-
Genomic and transcriptional aberrations linked to breast cancer pathophysiologies
-
10.1016/j.ccr.2006.10.009, 17157792
-
Chin K, DeVries S, Fridlyand J, Spellman PT, Roydasgupta R, Kuo WL, Lapuk A, Neve RM, Qian Z, Ryder T, Chen F, Feiler H, Tokuyasu T, Kingsley C, Dairkee S, Meng Z, Chew K, Pinkel D, Jain A, Ljung BM, Esserman L, Albertson DG, Waldman FM, Gray JW. Genomic and transcriptional aberrations linked to breast cancer pathophysiologies. Cancer Cell 2006, 10:529-541. 10.1016/j.ccr.2006.10.009, 17157792.
-
(2006)
Cancer Cell
, vol.10
, pp. 529-541
-
-
Chin, K.1
DeVries, S.2
Fridlyand, J.3
Spellman, P.T.4
Roydasgupta, R.5
Kuo, W.L.6
Lapuk, A.7
Neve, R.M.8
Qian, Z.9
Ryder, T.10
Chen, F.11
Feiler, H.12
Tokuyasu, T.13
Kingsley, C.14
Dairkee, S.15
Meng, Z.16
Chew, K.17
Pinkel, D.18
Jain, A.19
Ljung, B.M.20
Esserman, L.21
Albertson, D.G.22
Waldman, F.M.23
Gray, J.W.24
more..
-
15
-
-
39749108733
-
High-resolution aCGH and expression profiling identifies a novel genomic subtype of ER negative breast cancer
-
10.1186/gb-2007-8-10-r215, 2246289, 17925008
-
Chin SF, Teschendorff AE, Marioni JC, Wang Y, Barbosa-Morais NL, Thorne NP, Costa JL, Pinder SE, van de Wiel MA, Green AR, Ellis IO, Porter PL, Tavare S, Brenton JD, Ylstra B, Caldas C. High-resolution aCGH and expression profiling identifies a novel genomic subtype of ER negative breast cancer. Genome Biol 2007, 8:R215. 10.1186/gb-2007-8-10-r215, 2246289, 17925008.
-
(2007)
Genome Biol
, vol.8
-
-
Chin, S.F.1
Teschendorff, A.E.2
Marioni, J.C.3
Wang, Y.4
Barbosa-Morais, N.L.5
Thorne, N.P.6
Costa, J.L.7
Pinder, S.E.8
van de Wiel, M.A.9
Green, A.R.10
Ellis, I.O.11
Porter, P.L.12
Tavare, S.13
Brenton, J.D.14
Ylstra, B.15
Caldas, C.16
-
16
-
-
70449584755
-
A high-resolution integrated analysis of genetic and expression profiles of breast cancer cell lines
-
10.1007/s10549-008-0296-7, 19169812
-
Mackay A, Tamber N, Fenwick K, Iravani M, Grigoriadis A, Dexter T, Lord CJ, Reis-Filho JS, Ashworth A. A high-resolution integrated analysis of genetic and expression profiles of breast cancer cell lines. Breast Cancer Res Treat 2009, 118:481-498. 10.1007/s10549-008-0296-7, 19169812.
-
(2009)
Breast Cancer Res Treat
, vol.118
, pp. 481-498
-
-
Mackay, A.1
Tamber, N.2
Fenwick, K.3
Iravani, M.4
Grigoriadis, A.5
Dexter, T.6
Lord, C.J.7
Reis-Filho, J.S.8
Ashworth, A.9
-
17
-
-
79952093026
-
ZNF703 is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium
-
10.1002/emmm.201100122, 21337521
-
Holland DG, Burleigh A, Git A, Goldgraben MA, Perez-Mancera PA, Chin SF, Hurtado A, Bruna A, Ali HR, Greenwood W, Dunning MJ, Samarajiwa S, Menon S, Rueda OM, Lynch AG, McKinney S, Ellis IO, Eaves CJ, Carroll JS, Curtis C, Aparicio S, Caldas C. ZNF703 is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium. EMBO Mol Med 2011, 3:167-180. 10.1002/emmm.201100122, 21337521.
-
(2011)
EMBO Mol Med
, vol.3
, pp. 167-180
-
-
Holland, D.G.1
Burleigh, A.2
Git, A.3
Goldgraben, M.A.4
Perez-Mancera, P.A.5
Chin, S.F.6
Hurtado, A.7
Bruna, A.8
Ali, H.R.9
Greenwood, W.10
Dunning, M.J.11
Samarajiwa, S.12
Menon, S.13
Rueda, O.M.14
Lynch, A.G.15
McKinney, S.16
Ellis, I.O.17
Eaves, C.J.18
Carroll, J.S.19
Curtis, C.20
Aparicio, S.21
Caldas, C.22
more..
-
18
-
-
79952078260
-
ZNF703 gene amplification at 8p12 specifies luminal B breast cancer
-
10.1002/emmm.201100121, 21328542
-
Sircoulomb F, Nicolas N, Ferrari A, Finetti P, Bekhouche I, Rousselet E, Lonigro A, Adelaide J, Baudelet E, Esteyries S, Wicinski J, Audebert S, Charafe-Jauffret E, Jacquemier J, Lopez M, Borg JP, Sotiriou C, Popovici C, Bertucci F, Birnbaum D, Chaffanet M, Ginestier C. ZNF703 gene amplification at 8p12 specifies luminal B breast cancer. EMBO Mol Med 2011, 3:153-166. 10.1002/emmm.201100121, 21328542.
-
(2011)
EMBO Mol Med
, vol.3
, pp. 153-166
-
-
Sircoulomb, F.1
Nicolas, N.2
Ferrari, A.3
Finetti, P.4
Bekhouche, I.5
Rousselet, E.6
Lonigro, A.7
Adelaide, J.8
Baudelet, E.9
Esteyries, S.10
Wicinski, J.11
Audebert, S.12
Charafe-Jauffret, E.13
Jacquemier, J.14
Lopez, M.15
Borg, J.P.16
Sotiriou, C.17
Popovici, C.18
Bertucci, F.19
Birnbaum, D.20
Chaffanet, M.21
Ginestier, C.22
more..
-
19
-
-
77950278598
-
FGFR1 amplification drives endocrine therapy resistance and is a therapeutic target in breast cancer
-
10.1158/0008-5472.CAN-09-3746, 2832818, 20179196
-
Turner N, Pearson A, Sharpe R, Lambros M, Geyer F, Lopez-Garcia MA, Natrajan R, Marchio C, Iorns E, Mackay A, Gillett C, Grigoriadis A, Tutt A, Reis-Filho JS, Ashworth A. FGFR1 amplification drives endocrine therapy resistance and is a therapeutic target in breast cancer. Cancer Res 2010, 70:2085-2094. 10.1158/0008-5472.CAN-09-3746, 2832818, 20179196.
-
(2010)
Cancer Res
, vol.70
, pp. 2085-2094
-
-
Turner, N.1
Pearson, A.2
Sharpe, R.3
Lambros, M.4
Geyer, F.5
Lopez-Garcia, M.A.6
Natrajan, R.7
Marchio, C.8
Iorns, E.9
Mackay, A.10
Gillett, C.11
Grigoriadis, A.12
Tutt, A.13
Reis-Filho, J.S.14
Ashworth, A.15
-
20
-
-
42549111727
-
Genomic analysis of the HER2/TOP2A amplicon in breast cancer and breast cancer cell lines
-
10.1038/labinvest.2008.19, 18332872
-
Arriola E, Marchio C, Tan DS, Drury SC, Lambros MB, Natrajan R, Rodriguez-Pinilla SM, Mackay A, Tamber N, Fenwick K, Jones C, Dowsett M, Ashworth A, Reis-Filho JS. Genomic analysis of the HER2/TOP2A amplicon in breast cancer and breast cancer cell lines. Lab Invest 2008, 88:491-503. 10.1038/labinvest.2008.19, 18332872.
-
(2008)
Lab Invest
, vol.88
, pp. 491-503
-
-
Arriola, E.1
Marchio, C.2
Tan, D.S.3
Drury, S.C.4
Lambros, M.B.5
Natrajan, R.6
Rodriguez-Pinilla, S.M.7
Mackay, A.8
Tamber, N.9
Fenwick, K.10
Jones, C.11
Dowsett, M.12
Ashworth, A.13
Reis-Filho, J.S.14
-
21
-
-
4644286709
-
Genomic and expression profiling of chromosome 17 in breast cancer reveals complex patterns of alterations and novel candidate genes
-
10.1158/0008-5472.CAN-04-0756, 15374954
-
Orsetti B, Nugoli M, Cervera N, Lasorsa L, Chuchana P, Ursule L, Nguyen C, Redon R, du Manoir S, Rodriguez C, Theillet C. Genomic and expression profiling of chromosome 17 in breast cancer reveals complex patterns of alterations and novel candidate genes. Cancer Res 2004, 64:6453-6460. 10.1158/0008-5472.CAN-04-0756, 15374954.
-
(2004)
Cancer Res
, vol.64
, pp. 6453-6460
-
-
Orsetti, B.1
Nugoli, M.2
Cervera, N.3
Lasorsa, L.4
Chuchana, P.5
Ursule, L.6
Nguyen, C.7
Redon, R.8
du Manoir, S.9
Rodriguez, C.10
Theillet, C.11
-
22
-
-
77957940993
-
High-resolution genomic and expression analyses of copy number alterations in HER2-amplified breast cancer
-
10.1186/bcr2568, 2917012, 20459607
-
Staaf J, Jonsson G, Ringner M, Vallon-Christersson J, Grabau D, Arason A, Gunnarsson H, Agnarsson BA, Malmstrom PO, Johannsson OT, Loman N, Barkardottir RB, Borg A. High-resolution genomic and expression analyses of copy number alterations in HER2-amplified breast cancer. Breast Cancer Res 2010, 12:R25. 10.1186/bcr2568, 2917012, 20459607.
-
(2010)
Breast Cancer Res
, vol.12
-
-
Staaf, J.1
Jonsson, G.2
Ringner, M.3
Vallon-Christersson, J.4
Grabau, D.5
Arason, A.6
Gunnarsson, H.7
Agnarsson, B.A.8
Malmstrom, P.O.9
Johannsson, O.T.10
Loman, N.11
Barkardottir, R.B.12
Borg, A.13
-
23
-
-
33745686009
-
RNA interference-based functional dissection of the 17q12 amplicon in breast cancer reveals contribution of coamplified genes
-
10.1002/gcc.20339, 16708353
-
Kao J, Pollack JR. RNA interference-based functional dissection of the 17q12 amplicon in breast cancer reveals contribution of coamplified genes. Genes Chromosomes Cancer 2006, 45:761-769. 10.1002/gcc.20339, 16708353.
-
(2006)
Genes Chromosomes Cancer
, vol.45
, pp. 761-769
-
-
Kao, J.1
Pollack, J.R.2
-
24
-
-
77957277092
-
DNA amplifications in breast cancer: genotypic-phenotypic correlations
-
10.2217/fon.10.56, 20528234
-
Shiu KK, Natrajan R, Geyer FC, Ashworth A, Reis-Filho JS. DNA amplifications in breast cancer: genotypic-phenotypic correlations. Future Oncol 2010, 6:967-984. 10.2217/fon.10.56, 20528234.
-
(2010)
Future Oncol
, vol.6
, pp. 967-984
-
-
Shiu, K.K.1
Natrajan, R.2
Geyer, F.C.3
Ashworth, A.4
Reis-Filho, J.S.5
-
25
-
-
34047132184
-
Transforming function of the LSM1 oncogene in human breast cancers with the 8p11-12 amplicon
-
10.1038/sj.onc.1210002, 2435249, 17001308
-
Streicher KL, Yang ZQ, Draghici S, Ethier SP. Transforming function of the LSM1 oncogene in human breast cancers with the 8p11-12 amplicon. Oncogene 2007, 26:2104-2114. 10.1038/sj.onc.1210002, 2435249, 17001308.
-
(2007)
Oncogene
, vol.26
, pp. 2104-2114
-
-
Streicher, K.L.1
Yang, Z.Q.2
Draghici, S.3
Ethier, S.P.4
-
26
-
-
37549006702
-
Integrated profiling of basal and luminal breast cancers
-
10.1158/0008-5472.CAN-07-2536, 18089785
-
Adelaide J, Finetti P, Bekhouche I, Repellini L, Geneix J, Sircoulomb F, Charafe-Jauffret E, Cervera N, Desplans J, Parzy D, Schoenmakers E, Viens P, Jacquemier J, Birnbaum D, Bertucci F, Chaffanet M. Integrated profiling of basal and luminal breast cancers. Cancer Res 2007, 67:11565-11575. 10.1158/0008-5472.CAN-07-2536, 18089785.
-
(2007)
Cancer Res
, vol.67
, pp. 11565-11575
-
-
Adelaide, J.1
Finetti, P.2
Bekhouche, I.3
Repellini, L.4
Geneix, J.5
Sircoulomb, F.6
Charafe-Jauffret, E.7
Cervera, N.8
Desplans, J.9
Parzy, D.10
Schoenmakers, E.11
Viens, P.12
Jacquemier, J.13
Birnbaum, D.14
Bertucci, F.15
Chaffanet, M.16
-
27
-
-
77954242252
-
Molecular profiling of invasive breast cancer by multiplex ligation-dependent probe amplification-based copy number analysis of tumor suppressor and oncogenes
-
10.1038/modpathol.2010.84, 20473280
-
Moelans CB, de Weger RA, Monsuur HN, Vijzelaar R, van Diest PJ. Molecular profiling of invasive breast cancer by multiplex ligation-dependent probe amplification-based copy number analysis of tumor suppressor and oncogenes. Mod Pathol 2010, 23:1029-1039. 10.1038/modpathol.2010.84, 20473280.
-
(2010)
Mod Pathol
, vol.23
, pp. 1029-1039
-
-
Moelans, C.B.1
de Weger, R.A.2
Monsuur, H.N.3
Vijzelaar, R.4
van Diest, P.J.5
-
28
-
-
33745185501
-
Which cyclin E prevails as prognostic marker for breast cancer? Results from a retrospective study involving 635 lymph node-negative breast cancer patients
-
10.1158/1078-0432.CCR-06-0225, 16740753
-
Sieuwerts AM, Look MP, Meijer-van Gelder ME, Timmermans M, Trapman AM, Garcia RR, Arnold M, Goedheer AJ, de Weerd V, Portengen H, Klijn JG, Foekens JA. Which cyclin E prevails as prognostic marker for breast cancer? Results from a retrospective study involving 635 lymph node-negative breast cancer patients. Clin Cancer Res 2006, 12:3319-3328. 10.1158/1078-0432.CCR-06-0225, 16740753.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 3319-3328
-
-
Sieuwerts, A.M.1
Look, M.P.2
Meijer-van Gelder, M.E.3
Timmermans, M.4
Trapman, A.M.5
Garcia, R.R.6
Arnold, M.7
Goedheer, A.J.8
de Weerd, V.9
Portengen, H.10
Klijn, J.G.11
Foekens, J.A.12
-
29
-
-
77953123909
-
An integrative genomic and transcriptomic analysis reveals molecular pathways and networks regulated by copy number aberrations in basal-like, HER2 and luminal cancers
-
10.1007/s10549-009-0501-3, 19688261
-
Natrajan R, Weigelt B, Mackay A, Geyer FC, Grigoriadis A, Tan DS, Jones C, Lord CJ, Vatcheva R, Rodriguez-Pinilla SM, Palacios J, Ashworth A, Reis-Filho JS. An integrative genomic and transcriptomic analysis reveals molecular pathways and networks regulated by copy number aberrations in basal-like, HER2 and luminal cancers. Breast Cancer Res Treat 2010, 121:575-589. 10.1007/s10549-009-0501-3, 19688261.
-
(2010)
Breast Cancer Res Treat
, vol.121
, pp. 575-589
-
-
Natrajan, R.1
Weigelt, B.2
Mackay, A.3
Geyer, F.C.4
Grigoriadis, A.5
Tan, D.S.6
Jones, C.7
Lord, C.J.8
Vatcheva, R.9
Rodriguez-Pinilla, S.M.10
Palacios, J.11
Ashworth, A.12
Reis-Filho, J.S.13
-
30
-
-
79959970420
-
Influence of whole arm loss of chromosome 16q on gene expression patterns in oestrogen receptor-positive, invasive breast cancer
-
10.1002/path.2938, 21706489
-
Hungermann D, Schmidt H, Natrajan R, Tidow N, Poos K, Reis-Filho JS, Brandt B, Buerger H, Korsching E. Influence of whole arm loss of chromosome 16q on gene expression patterns in oestrogen receptor-positive, invasive breast cancer. J Pathol 2011, 224:517-528. 10.1002/path.2938, 21706489.
-
(2011)
J Pathol
, vol.224
, pp. 517-528
-
-
Hungermann, D.1
Schmidt, H.2
Natrajan, R.3
Tidow, N.4
Poos, K.5
Reis-Filho, J.S.6
Brandt, B.7
Buerger, H.8
Korsching, E.9
-
31
-
-
77955551924
-
Analysis of breast cancer related gene expression using natural splines and the Cox proportional hazard model to identify prognostic associations
-
10.1007/s10549-009-0588-6, 19859804
-
Kreike B, Hart G, Bartelink H, van de Vijver MJ. Analysis of breast cancer related gene expression using natural splines and the Cox proportional hazard model to identify prognostic associations. Breast Cancer Res Treat 2010, 122:711-720. 10.1007/s10549-009-0588-6, 19859804.
-
(2010)
Breast Cancer Res Treat
, vol.122
, pp. 711-720
-
-
Kreike, B.1
Hart, G.2
Bartelink, H.3
van de Vijver, M.J.4
-
32
-
-
0036432767
-
Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up
-
Elston CW, Ellis IO. Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up. Histopathology 2002, 41:154-161.
-
(2002)
Histopathology
, vol.41
, pp. 154-161
-
-
Elston, C.W.1
Ellis, I.O.2
-
33
-
-
77958022477
-
Mucinous carcinoma of the breast is genomically distinct from invasive ductal carcinomas of no special type
-
10.1002/path.2763, 20815046
-
Lacroix-Triki M, Suarez PH, MacKay A, Lambros MB, Natrajan R, Savage K, Geyer FC, Weigelt B, Ashworth A, Reis-Filho JS. Mucinous carcinoma of the breast is genomically distinct from invasive ductal carcinomas of no special type. J Pathol 2010, 222:282-298. 10.1002/path.2763, 20815046.
-
(2010)
J Pathol
, vol.222
, pp. 282-298
-
-
Lacroix-Triki, M.1
Suarez, P.H.2
MacKay, A.3
Lambros, M.B.4
Natrajan, R.5
Savage, K.6
Geyer, F.C.7
Weigelt, B.8
Ashworth, A.9
Reis-Filho, J.S.10
-
34
-
-
58149330982
-
Meta-analysis of gene expression profiles in breast cancer: toward a unified understanding of breast cancer subtyping and prognosis signatures
-
10.1186/bcr2124, 2575538, 18662380
-
Wirapati P, Sotiriou C, Kunkel S, Farmer P, Pradervand S, Haibe-Kains B, Desmedt C, Ignatiadis M, Sengstag T, Schutz F, Goldstein DR, Piccart M, Delorenzi M. Meta-analysis of gene expression profiles in breast cancer: toward a unified understanding of breast cancer subtyping and prognosis signatures. Breast Cancer Res 2008, 10:R65. 10.1186/bcr2124, 2575538, 18662380.
-
(2008)
Breast Cancer Res
, vol.10
-
-
Wirapati, P.1
Sotiriou, C.2
Kunkel, S.3
Farmer, P.4
Pradervand, S.5
Haibe-Kains, B.6
Desmedt, C.7
Ignatiadis, M.8
Sengstag, T.9
Schutz, F.10
Goldstein, D.R.11
Piccart, M.12
Delorenzi, M.13
-
35
-
-
51349088017
-
Biological processes associated with breast cancer clinical outcome depend on the molecular subtypes
-
10.1158/1078-0432.CCR-07-4756, 18698033
-
Desmedt C, Haibe-Kains B, Wirapati P, Buyse M, Larsimont D, Bontempi G, Delorenzi M, Piccart M, Sotiriou C. Biological processes associated with breast cancer clinical outcome depend on the molecular subtypes. Clin Cancer Res 2008, 14:5158-5165. 10.1158/1078-0432.CCR-07-4756, 18698033.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 5158-5165
-
-
Desmedt, C.1
Haibe-Kains, B.2
Wirapati, P.3
Buyse, M.4
Larsimont, D.5
Bontempi, G.6
Delorenzi, M.7
Piccart, M.8
Sotiriou, C.9
-
36
-
-
77950308839
-
Breast cancer molecular profiling with single sample predictors: a retrospective analysis
-
10.1016/S1470-2045(10)70008-5, 20181526
-
Weigelt B, Mackay A, A'Hern R, Natrajan R, Tan DS, Dowsett M, Ashworth A, Reis-Filho JS. Breast cancer molecular profiling with single sample predictors: a retrospective analysis. Lancet Oncol 2010, 11:339-349. 10.1016/S1470-2045(10)70008-5, 20181526.
-
(2010)
Lancet Oncol
, vol.11
, pp. 339-349
-
-
Weigelt, B.1
Mackay, A.2
A'Hern, R.3
Natrajan, R.4
Tan, D.S.5
Dowsett, M.6
Ashworth, A.7
Reis-Filho, J.S.8
-
37
-
-
84857782927
-
A refined molecular taxonomy of breast cancer
-
10.1038/onc.2011.301, 3307061, 21785460
-
Guedj M, Marisa L, de Reynies A, Orsetti B, Schiappa R, Bibeau F, Macgrogan G, Lerebours F, Finetti P, Longy M, Bertheau P, Bertrand F, Bonnet F, Martin AL, Feugeas JP, Bieche I, Lehmann-Che J, Lidereau R, Birnbaum D, Bertucci F, de Thé H, Theillet C. A refined molecular taxonomy of breast cancer. Oncogene 2012, 31:1196-1206. 10.1038/onc.2011.301, 3307061, 21785460.
-
(2012)
Oncogene
, vol.31
, pp. 1196-1206
-
-
Guedj, M.1
Marisa, L.2
de Reynies, A.3
Orsetti, B.4
Schiappa, R.5
Bibeau, F.6
Macgrogan, G.7
Lerebours, F.8
Finetti, P.9
Longy, M.10
Bertheau, P.11
Bertrand, F.12
Bonnet, F.13
Martin, A.L.14
Feugeas, J.P.15
Bieche, I.16
Lehmann-Che, J.17
Lidereau, R.18
Birnbaum, D.19
Bertucci, F.20
de Thé, H.21
Theillet, C.22
more..
-
38
-
-
33845209913
-
A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes
-
10.1016/j.ccr.2006.10.008, 2730521, 17157791
-
Neve RM, Chin K, Fridlyand J, Yeh J, Baehner FL, Fevr T, Clark L, Bayani N, Coppe JP, Tong F, Speed T, Spellman PT, DeVries S, Lapuk A, Wang NJ, Kuo WL, Stilwell JL, Pinkel D, Albertson DG, Waldman FM, McCormick F, Dickson RB, Johnson MD, Lippman M, Ethier S, Gazdar A, Gray JW. A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. Cancer Cell 2006, 10:515-527. 10.1016/j.ccr.2006.10.008, 2730521, 17157791.
-
(2006)
Cancer Cell
, vol.10
, pp. 515-527
-
-
Neve, R.M.1
Chin, K.2
Fridlyand, J.3
Yeh, J.4
Baehner, F.L.5
Fevr, T.6
Clark, L.7
Bayani, N.8
Coppe, J.P.9
Tong, F.10
Speed, T.11
Spellman, P.T.12
DeVries, S.13
Lapuk, A.14
Wang, N.J.15
Kuo, W.L.16
Stilwell, J.L.17
Pinkel, D.18
Albertson, D.G.19
Waldman, F.M.20
McCormick, F.21
Dickson, R.B.22
Johnson, M.D.23
Lippman, M.24
Ethier, S.25
Gazdar, A.26
Gray, J.W.27
more..
-
39
-
-
77949809850
-
Molecular analysis reveals a genetic basis for the phenotypic diversity of metaplastic breast carcinomas
-
10.1002/path.2675, 20099298
-
Geyer FC, Weigelt B, Natrajan R, Lambros MB, de Biase D, Vatcheva R, Savage K, Mackay A, Ashworth A, Reis-Filho JS. Molecular analysis reveals a genetic basis for the phenotypic diversity of metaplastic breast carcinomas. J Pathol 2010, 220:562-573. 10.1002/path.2675, 20099298.
-
(2010)
J Pathol
, vol.220
, pp. 562-573
-
-
Geyer, F.C.1
Weigelt, B.2
Natrajan, R.3
Lambros, M.B.4
de Biase, D.5
Vatcheva, R.6
Savage, K.7
Mackay, A.8
Ashworth, A.9
Reis-Filho, J.S.10
-
40
-
-
34247124695
-
Resolving the resolution of array CGH
-
10.1016/j.ygeno.2006.12.012, 17276656
-
Coe BP, Ylstra B, Carvalho B, Meijer GA, Macaulay C, Lam WL. Resolving the resolution of array CGH. Genomics 2007, 89:647-653. 10.1016/j.ygeno.2006.12.012, 17276656.
-
(2007)
Genomics
, vol.89
, pp. 647-653
-
-
Coe, B.P.1
Ylstra, B.2
Carvalho, B.3
Meijer, G.A.4
Macaulay, C.5
Lam, W.L.6
-
41
-
-
45349086985
-
Screening for copy-number alterations and loss of heterozygosity in chronic lymphocytic leukemia--a comparative study of four differently designed, high resolution microarray platforms
-
10.1002/gcc.20575, 18484635
-
Gunnarsson R, Staaf J, Jansson M, Ottesen AM, Goransson H, Liljedahl U, Ralfkiaer U, Mansouri M, Buhl AM, Smedby KE, Hjalgrim H, Syvanen AC, Borg A, Isaksson A, Jurlander J, Juliusson G, Rosenquist R. Screening for copy-number alterations and loss of heterozygosity in chronic lymphocytic leukemia--a comparative study of four differently designed, high resolution microarray platforms. Genes Chromosomes Cancer 2008, 47:697-711. 10.1002/gcc.20575, 18484635.
-
(2008)
Genes Chromosomes Cancer
, vol.47
, pp. 697-711
-
-
Gunnarsson, R.1
Staaf, J.2
Jansson, M.3
Ottesen, A.M.4
Goransson, H.5
Liljedahl, U.6
Ralfkiaer, U.7
Mansouri, M.8
Buhl, A.M.9
Smedby, K.E.10
Hjalgrim, H.11
Syvanen, A.C.12
Borg, A.13
Isaksson, A.14
Jurlander, J.15
Juliusson, G.16
Rosenquist, R.17
-
42
-
-
34447552512
-
Getting it right: designing microarray (and not 'microawry') comparative genomic hybridization studies for cancer research
-
10.1038/labinvest.3700593, 17558419
-
Tan DS, Lambros MB, Natrajan R, Reis-Filho JS. Getting it right: designing microarray (and not 'microawry') comparative genomic hybridization studies for cancer research. Lab Invest 2007, 87:737-754. 10.1038/labinvest.3700593, 17558419.
-
(2007)
Lab Invest
, vol.87
, pp. 737-754
-
-
Tan, D.S.1
Lambros, M.B.2
Natrajan, R.3
Reis-Filho, J.S.4
-
43
-
-
84870923207
-
Ensembl Genome Browser
-
Ensembl Genome Browser. , http://www.ensembl.org
-
-
-
-
44
-
-
79960902511
-
Functional characterization of EMSY gene amplification in human cancers
-
10.1002/path.2944, 21735447
-
Wilkerson PM, Dedes KJ, Wetterskog D, Mackay A, Lambros MB, Mansour M, Frankum J, Lord CJ, Natrajan R, Ashworth A, Reis-Filho JS. Functional characterization of EMSY gene amplification in human cancers. J Pathol 2011, 225:29-42. 10.1002/path.2944, 21735447.
-
(2011)
J Pathol
, vol.225
, pp. 29-42
-
-
Wilkerson, P.M.1
Dedes, K.J.2
Wetterskog, D.3
Mackay, A.4
Lambros, M.B.5
Mansour, M.6
Frankum, J.7
Lord, C.J.8
Natrajan, R.9
Ashworth, A.10
Reis-Filho, J.S.11
-
45
-
-
68849111431
-
Does chromosome 17 centromere copy number predict polysomy in breast cancer? A fluorescence in situ hybridization and microarray-based CGH analysis
-
10.1002/path.2574, 19670217
-
Marchio C, Lambros MB, Gugliotta P, Di Cantogno LV, Botta C, Pasini B, Tan DS, Mackay A, Fenwick K, Tamber N, Bussolati G, Ashworth A, Reis-Filho JS, Sapino A. Does chromosome 17 centromere copy number predict polysomy in breast cancer? A fluorescence in situ hybridization and microarray-based CGH analysis. J Pathol 2009, 219:16-24. 10.1002/path.2574, 19670217.
-
(2009)
J Pathol
, vol.219
, pp. 16-24
-
-
Marchio, C.1
Lambros, M.B.2
Gugliotta, P.3
Di Cantogno, L.V.4
Botta, C.5
Pasini, B.6
Tan, D.S.7
Mackay, A.8
Fenwick, K.9
Tamber, N.10
Bussolati, G.11
Ashworth, A.12
Reis-Filho, J.S.13
Sapino, A.14
-
46
-
-
84856048158
-
Immunophenotypic and genomic characterization of papillary carcinomas of the breast
-
10.1002/path.3032, 22025283
-
Duprez R, Wilkerson PM, Lacroix-Triki M, Lambros MB, Mackay A, Hern RA, Gauthier A, Pawar V, Colombo PE, Daley F, Natrajan R, Ward E, Macgrogan G, Arbion F, Michenet P, Weigelt B, Vincent-Salomon A, Reis-Filho JS. Immunophenotypic and genomic characterization of papillary carcinomas of the breast. J Pathol 2012, 226:427-441. 10.1002/path.3032, 22025283.
-
(2012)
J Pathol
, vol.226
, pp. 427-441
-
-
Duprez, R.1
Wilkerson, P.M.2
Lacroix-Triki, M.3
Lambros, M.B.4
Mackay, A.5
Hern, R.A.6
Gauthier, A.7
Pawar, V.8
Colombo, P.E.9
Daley, F.10
Natrajan, R.11
Ward, E.12
Macgrogan, G.13
Arbion, F.14
Michenet, P.15
Weigelt, B.16
Vincent-Salomon, A.17
Reis-Filho, J.S.18
-
47
-
-
84860916734
-
Natrajan.19q12.amplicon
-
Natrajan.19q12.amplicon. , http://www.rock.icr.ac.uk/collaborations/Natrajan/19q12.amplicon/
-
-
-
-
48
-
-
33645326209
-
Unlocking pathology archives for molecular genetic studies: a reliable method to generate probes for chromogenic and fluorescent in situ hybridization
-
10.1038/labinvest.3700390, 16446704
-
Lambros MB, Simpson PT, Jones C, Natrajan R, Westbury C, Steele D, Savage K, Mackay A, Schmitt FC, Ashworth A, Reis-Filho JS. Unlocking pathology archives for molecular genetic studies: a reliable method to generate probes for chromogenic and fluorescent in situ hybridization. Lab Invest 2006, 86:398-408. 10.1038/labinvest.3700390, 16446704.
-
(2006)
Lab Invest
, vol.86
, pp. 398-408
-
-
Lambros, M.B.1
Simpson, P.T.2
Jones, C.3
Natrajan, R.4
Westbury, C.5
Steele, D.6
Savage, K.7
Mackay, A.8
Schmitt, F.C.9
Ashworth, A.10
Reis-Filho, J.S.11
-
49
-
-
67349118370
-
Full sequencing of TP53 identifies identical mutations within in situ and invasive components in breast cancer suggesting clonal evolution
-
10.1016/j.molonc.2009.03.001, 19403344
-
Zhou W, Muggerud AA, Vu P, Due EU, Sørlie T, Børresen-Dale AL, Warnberg F, Langerod A. Full sequencing of TP53 identifies identical mutations within in situ and invasive components in breast cancer suggesting clonal evolution. Mol Oncol 2009, 3:214-219. 10.1016/j.molonc.2009.03.001, 19403344.
-
(2009)
Mol Oncol
, vol.3
, pp. 214-219
-
-
Zhou, W.1
Muggerud, A.A.2
Vu, P.3
Due, E.U.4
Sørlie, T.5
Børresen-Dale, A.L.6
Warnberg, F.7
Langerod, A.8
-
50
-
-
58149147318
-
TP53 mutational analysis supports monoclonal origin of biphasic sarcomatoid urothelial carcinoma (carcinosarcoma) of the urinary bladder
-
10.1038/modpathol.2008.176, 18997737
-
Armstrong AB, Wang M, Eble JN, MacLennan GT, Montironi R, Tan PH, Lopez-Beltran A, Zhang S, Baldridge LA, Spartz H, Cheng L. TP53 mutational analysis supports monoclonal origin of biphasic sarcomatoid urothelial carcinoma (carcinosarcoma) of the urinary bladder. Mod Pathol 2009, 22:113-118. 10.1038/modpathol.2008.176, 18997737.
-
(2009)
Mod Pathol
, vol.22
, pp. 113-118
-
-
Armstrong, A.B.1
Wang, M.2
Eble, J.N.3
MacLennan, G.T.4
Montironi, R.5
Tan, P.H.6
Lopez-Beltran, A.7
Zhang, S.8
Baldridge, L.A.9
Spartz, H.10
Cheng, L.11
-
51
-
-
29144464381
-
ArrayExpress
-
ArrayExpress. , http://www.ebi.ac.uk/microarray-as/ae/
-
-
-
-
52
-
-
43249085571
-
A synthetic lethal siRNA screen identifying genes mediating sensitivity to a PARP inhibitor
-
10.1038/emboj.2008.61, 2374839, 18388863
-
Turner NC, Lord CJ, Iorns E, Brough R, Swift S, Elliott R, Rayter S, Tutt AN, Ashworth A. A synthetic lethal siRNA screen identifying genes mediating sensitivity to a PARP inhibitor. EMBO J 2008, 27:1368-1377. 10.1038/emboj.2008.61, 2374839, 18388863.
-
(2008)
EMBO J
, vol.27
, pp. 1368-1377
-
-
Turner, N.C.1
Lord, C.J.2
Iorns, E.3
Brough, R.4
Swift, S.5
Elliott, R.6
Rayter, S.7
Tutt, A.N.8
Ashworth, A.9
-
53
-
-
84860916798
-
ImageJ
-
ImageJ. , http://rsbweb.nih.gov/ij/index.html
-
-
-
-
54
-
-
9144271680
-
The RAB25 small GTPase determines aggressiveness of ovarian and breast cancers
-
10.1038/nm1125, 15502842
-
Cheng KW, Lahad JP, Kuo WL, Lapuk A, Yamada K, Auersperg N, Liu J, Smith-McCune K, Lu KH, Fishman D, Gray JW, Mills GB. The RAB25 small GTPase determines aggressiveness of ovarian and breast cancers. Nat Med 2004, 10:1251-1256. 10.1038/nm1125, 15502842.
-
(2004)
Nat Med
, vol.10
, pp. 1251-1256
-
-
Cheng, K.W.1
Lahad, J.P.2
Kuo, W.L.3
Lapuk, A.4
Yamada, K.5
Auersperg, N.6
Liu, J.7
Smith-McCune, K.8
Lu, K.H.9
Fishman, D.10
Gray, J.W.11
Mills, G.B.12
-
55
-
-
60749109846
-
Cell cycle, CDKs and cancer: a changing paradigm
-
10.1038/nrc2602, 19238148
-
Malumbres M, Barbacid M. Cell cycle, CDKs and cancer: a changing paradigm. Nat Rev Cancer 2009, 9:153-166. 10.1038/nrc2602, 19238148.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 153-166
-
-
Malumbres, M.1
Barbacid, M.2
-
56
-
-
53349164228
-
Imidazoles: SAR and development of a potent class of cyclin-dependent kinase inhibitors
-
10.1016/j.bmcl.2008.09.024, 18815031
-
Anderson M, Andrews DM, Barker AJ, Brassington CA, Breed J, Byth KF, Culshaw JD, Finlay MR, Fisher E, McMiken HH, Green CP, Heaton DW, Nash IA, Newcombe NJ, Oakes SE, Pauptit RA, Roberts A, Stanway JJ, Thomas AP, Tucker JA, Walker M, Weir HM. Imidazoles: SAR and development of a potent class of cyclin-dependent kinase inhibitors. Bioorg Med Chem Lett 2008, 18:5487-5492. 10.1016/j.bmcl.2008.09.024, 18815031.
-
(2008)
Bioorg Med Chem Lett
, vol.18
, pp. 5487-5492
-
-
Anderson, M.1
Andrews, D.M.2
Barker, A.J.3
Brassington, C.A.4
Breed, J.5
Byth, K.F.6
Culshaw, J.D.7
Finlay, M.R.8
Fisher, E.9
McMiken, H.H.10
Green, C.P.11
Heaton, D.W.12
Nash, I.A.13
Newcombe, N.J.14
Oakes, S.E.15
Pauptit, R.A.16
Roberts, A.17
Stanway, J.J.18
Thomas, A.P.19
Tucker, J.A.20
Walker, M.21
Weir, H.M.22
more..
-
57
-
-
67651177588
-
AZD5438, a potent oral inhibitor of cyclin-dependent kinases 1, 2, and 9, leads to pharmacodynamic changes and potent antitumor effects in human tumor xenografts
-
10.1158/1535-7163.MCT-08-0836, 19509270
-
Byth KF, Thomas A, Hughes G, Forder C, McGregor A, Geh C, Oakes S, Green C, Walker M, Newcombe N, Green S, Growcott J, Barker A, Wilkinson RW. AZD5438, a potent oral inhibitor of cyclin-dependent kinases 1, 2, and 9, leads to pharmacodynamic changes and potent antitumor effects in human tumor xenografts. Mol Cancer Ther 2009, 8:1856-1866. 10.1158/1535-7163.MCT-08-0836, 19509270.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 1856-1866
-
-
Byth, K.F.1
Thomas, A.2
Hughes, G.3
Forder, C.4
McGregor, A.5
Geh, C.6
Oakes, S.7
Green, C.8
Walker, M.9
Newcombe, N.10
Green, S.11
Growcott, J.12
Barker, A.13
Wilkinson, R.W.14
-
58
-
-
33847022042
-
BRCA1 dysfunction in sporadic basal-like breast cancer
-
10.1038/sj.onc.1210014, 17016441
-
Turner NC, Reis-Filho JS, Russell AM, Springall RJ, Ryder K, Steele D, Savage K, Gillett CE, Schmitt FC, Ashworth A, Tutt AN. BRCA1 dysfunction in sporadic basal-like breast cancer. Oncogene 2007, 26:2126-2132. 10.1038/sj.onc.1210014, 17016441.
-
(2007)
Oncogene
, vol.26
, pp. 2126-2132
-
-
Turner, N.C.1
Reis-Filho, J.S.2
Russell, A.M.3
Springall, R.J.4
Ryder, K.5
Steele, D.6
Savage, K.7
Gillett, C.E.8
Schmitt, F.C.9
Ashworth, A.10
Tutt, A.N.11
-
59
-
-
33646869235
-
Comprehensive analysis of 19q12 amplicon in human gastric cancers
-
Leung SY, Ho C, Tu IP, Li R, So S, Chu KM, Yuen ST, Chen X. Comprehensive analysis of 19q12 amplicon in human gastric cancers. Mod Pathol 2006, 19:854-863.
-
(2006)
Mod Pathol
, vol.19
, pp. 854-863
-
-
Leung, S.Y.1
Ho, C.2
Tu, I.P.3
Li, R.4
So, S.5
Chu, K.M.6
Yuen, S.T.7
Chen, X.8
-
60
-
-
0030845817
-
Mapping of DNA amplifications at 15 chromosomal localizations in 1875 breast tumors: definition of phenotypic groups
-
Courjal F, Cuny M, Simony-Lafontaine J, Louason G, Speiser P, Zeillinger R, Rodriguez C, Theillet C. Mapping of DNA amplifications at 15 chromosomal localizations in 1875 breast tumors: definition of phenotypic groups. Cancer Res 1997, 57:4360-4367.
-
(1997)
Cancer Res
, vol.57
, pp. 4360-4367
-
-
Courjal, F.1
Cuny, M.2
Simony-Lafontaine, J.3
Louason, G.4
Speiser, P.5
Zeillinger, R.6
Rodriguez, C.7
Theillet, C.8
-
61
-
-
28844490007
-
The lysosome-associated apoptosis-inducing protein containing the pleckstrin homology (PH) and FYVE domains (LAPF), representative of a novel family of PH and FYVE domain-containing proteins, induces caspase-independent apoptosis via the lysosomal-mitochondrial pathway
-
10.1074/jbc.M502190200, 16188880
-
Chen W, Li N, Chen T, Han Y, Li C, Wang Y, He W, Zhang L, Wan T, Cao X. The lysosome-associated apoptosis-inducing protein containing the pleckstrin homology (PH) and FYVE domains (LAPF), representative of a novel family of PH and FYVE domain-containing proteins, induces caspase-independent apoptosis via the lysosomal-mitochondrial pathway. J Biol Chem 2005, 280:40985-40995. 10.1074/jbc.M502190200, 16188880.
-
(2005)
J Biol Chem
, vol.280
, pp. 40985-40995
-
-
Chen, W.1
Li, N.2
Chen, T.3
Han, Y.4
Li, C.5
Wang, Y.6
He, W.7
Zhang, L.8
Wan, T.9
Cao, X.10
-
62
-
-
37048999377
-
Adaptor protein LAPF recruits phosphorylated p53 to lysosomes and triggers lysosomal destabilization in apoptosis
-
10.1158/0008-5472.CAN-07-2333, 18056442
-
Li N, Zheng Y, Chen W, Wang C, Liu X, He W, Xu H, Cao X. Adaptor protein LAPF recruits phosphorylated p53 to lysosomes and triggers lysosomal destabilization in apoptosis. Cancer Res 2007, 67:11176-11185. 10.1158/0008-5472.CAN-07-2333, 18056442.
-
(2007)
Cancer Res
, vol.67
, pp. 11176-11185
-
-
Li, N.1
Zheng, Y.2
Chen, W.3
Wang, C.4
Liu, X.5
He, W.6
Xu, H.7
Cao, X.8
-
63
-
-
58149399325
-
Teashirt 3 is necessary for ureteral smooth muscle differentiation downstream of SHH and BMP4
-
10.1242/dev.022442, 18776146
-
Caubit X, Lye CM, Martin E, Core N, Long DA, Vola C, Jenkins D, Garratt AN, Skaer H, Woolf AS, Fasano L. Teashirt 3 is necessary for ureteral smooth muscle differentiation downstream of SHH and BMP4. Development 2008, 135:3301-3310. 10.1242/dev.022442, 18776146.
-
(2008)
Development
, vol.135
, pp. 3301-3310
-
-
Caubit, X.1
Lye, C.M.2
Martin, E.3
Core, N.4
Long, D.A.5
Vola, C.6
Jenkins, D.7
Garratt, A.N.8
Skaer, H.9
Woolf, A.S.10
Fasano, L.11
-
64
-
-
79959565621
-
Teashirt-3, a novel regulator of muscle differentiation, associates with BRG-1 associated factor 57 (BAF57) to inhibit myogenin gene expression
-
Faralli H, Martin E, Core N, Liu QC, Filippi P, Dilworth FJ, Caubit X, Fasano L. Teashirt-3, a novel regulator of muscle differentiation, associates with BRG-1 associated factor 57 (BAF57) to inhibit myogenin gene expression. J Biol Chem 2011,
-
(2011)
J Biol Chem
-
-
Faralli, H.1
Martin, E.2
Core, N.3
Liu, Q.C.4
Filippi, P.5
Dilworth, F.J.6
Caubit, X.7
Fasano, L.8
-
65
-
-
79952674006
-
Rare and frequent promoter methylation, respectively, of TSHZ2 and 3 genes that are both downregulated in expression in breast and prostate cancers
-
10.1371/journal.pone.0017149, 3056709, 21423795
-
Yamamoto M, Cid E, Bru S, Yamamoto F. Rare and frequent promoter methylation, respectively, of TSHZ2 and 3 genes that are both downregulated in expression in breast and prostate cancers. PLoS One 2011, 6:e17149. 10.1371/journal.pone.0017149, 3056709, 21423795.
-
(2011)
PLoS One
, vol.6
-
-
Yamamoto, M.1
Cid, E.2
Bru, S.3
Yamamoto, F.4
-
66
-
-
77952835103
-
Gene amplification CCNE1 is related to poor survival and potential therapeutic target in ovarian cancer
-
Nakayama N, Nakayama K, Shamima Y, Ishikawa M, Katagiri A, Iida K, Miyazaki K. Gene amplification CCNE1 is related to poor survival and potential therapeutic target in ovarian cancer. Cancer 2010, 116:2621-2634.
-
(2010)
Cancer
, vol.116
, pp. 2621-2634
-
-
Nakayama, N.1
Nakayama, K.2
Shamima, Y.3
Ishikawa, M.4
Katagiri, A.5
Iida, K.6
Miyazaki, K.7
-
67
-
-
78649751900
-
Amplicon-dependent CCNE1 expression is critical for clonogenic survival after cisplatin treatment and is correlated with 20q11 gain in ovarian cancer
-
10.1371/journal.pone.0015498, 2980490, 21103391
-
Etemadmoghadam D, George J, Cowin PA, Cullinane C, Kansara M, Gorringe KL, Smyth GK, Bowtell DD. Amplicon-dependent CCNE1 expression is critical for clonogenic survival after cisplatin treatment and is correlated with 20q11 gain in ovarian cancer. PLoS One 2010, 5:e15498. 10.1371/journal.pone.0015498, 2980490, 21103391.
-
(2010)
PLoS One
, vol.5
-
-
Etemadmoghadam, D.1
George, J.2
Cowin, P.A.3
Cullinane, C.4
Kansara, M.5
Gorringe, K.L.6
Smyth, G.K.7
Bowtell, D.D.8
-
68
-
-
79955490608
-
Cdk2 is required for breast cancer mediated by the low-molecular-weight isoform of Cyclin E
-
10.1158/0008-5472.CAN-10-4086, 21385896
-
Akli S, Van Pelt CS, Bui T, Meijer L, Keyomarsi K. Cdk2 is required for breast cancer mediated by the low-molecular-weight isoform of Cyclin E. Cancer Res 2011, 71:3377-3386. 10.1158/0008-5472.CAN-10-4086, 21385896.
-
(2011)
Cancer Res
, vol.71
, pp. 3377-3386
-
-
Akli, S.1
Van Pelt, C.S.2
Bui, T.3
Meijer, L.4
Keyomarsi, K.5
-
69
-
-
85018914631
-
The TP53 website
-
The TP53 website. , http://p53.free.fr/Database/Cancer_cell_lines/Breast_cancer.html
-
-
-
-
70
-
-
79951834644
-
Catalogue Of Somatic Mutations In Cancer
-
Catalogue Of Somatic Mutations In Cancer. , http://www.sanger.ac.uk/genetics/CGP/cosmic/
-
-
-
|