TP53 mutational analysis supports monoclonal origin of biphasic sarcomatoid urothelial carcinoma (carcinosarcoma) of the urinary bladder

Modern Pathology

Volumn 22, Issue 1, 2009, Pages 113-118

  Armstrong, Andrew B ^a   Wang, Mingsheng ^a   Eble, John N ^a   MacLennan, Gregory T ^b   Montironi, Rodolfo ^c   Tan, Puay Hoon ^d   Lopez Beltran, Antonio ^e   Zhang, Shaobo ^a   Baldridge, Lee Ann ^a   Spartz, Helena ^a   Cheng, Liang ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CASE WESTERN RESERVE UNIVERSITY   (United States)

^c UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^d SINGAPORE GENERAL HOSPITAL   (Singapore)

^e UNIVERSITY OF CÓRDOBA   (Spain)

Author keywords

Cancer stem cells; Clonality; Molecular genetics; Sarcomatoid urothelial carcinoma; Tumorigenesis; Urinary bladder

Indexed keywords

PROTEIN P53;

ADULT; AGED; ARTICLE; BLADDER CARCINOMA; CARCINOGENESIS; CLINICAL ARTICLE; CONTROLLED STUDY; DNA POLYMORPHISM; DNA SEQUENCE; EXON; FEMALE; HUMAN; HUMAN TISSUE; MALE; MUTATIONAL ANALYSIS; POINT MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ADULT; AGED; AGED, 80 AND OVER; CARCINOSARCOMA; CELL LINEAGE; CLONE CELLS; DNA MUTATIONAL ANALYSIS; DNA, NEOPLASM; FEMALE; GENES, P53; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICRODISSECTION; MIDDLE AGED; MUTATION; NEOPLASTIC STEM CELLS; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE-STRANDED CONFORMATIONAL; TUMOR SUPPRESSOR PROTEIN P53; URINARY BLADDER NEOPLASMS;

EID: 58149147318     PISSN: 08933952     EISSN: 15300285     Source Type: Journal    
DOI: 10.1038/modpathol.2008.176     Document Type: Article

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