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Volumn 68, Issue 17, 2008, Pages 7165-7175

Characterization of the recurrent 8p11-12 amplicon identifies PPAPDC1B, a phosphatase protein, as a new therapeutic target in breast cancer

Author keywords

[No Author keywords available]

Indexed keywords

JANUS KINASE; MITOGEN ACTIVATED PROTEIN KINASE; ONCOPROTEIN; PHOSPHATASE; PHOSPHATIDATE PHOSPHATASE; PROTEIN BAG4; PROTEIN DDHD2; PROTEIN KINASE C; PROTEIN LSM1; PROTEIN PPAPDC1B; PROTEIN WHSC1L1; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; DPPL1 PROTEIN, HUMAN; PHOSPHOPROTEIN PHOSPHATASE; PRIMER DNA;

EID: 52049083886     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-08-1360     Document Type: Article
Times cited : (78)

References (47)
  • 1
    • 17944376262 scopus 로고    scopus 로고
    • Comprehensive genome sequence analysis of a breast cancer amplicon
    • Collins C, Volik S, Kowbel D, et al. Comprehensive genome sequence analysis of a breast cancer amplicon. Genome Res 2001;11:1034-42.
    • (2001) Genome Res , vol.11 , pp. 1034-1042
    • Collins, C.1    Volik, S.2    Kowbel, D.3
  • 2
    • 0036829790 scopus 로고    scopus 로고
    • Impact of DNA amplification on gene expression patterns in breast cancer
    • Hyman E, Kauraniemi P, Hautaniemi S, et al. Impact of DNA amplification on gene expression patterns in breast cancer. Cancer Res 2002;62:6240-5.
    • (2002) Cancer Res , vol.62 , pp. 6240-6245
    • Hyman, E.1    Kauraniemi, P.2    Hautaniemi, S.3
  • 3
    • 9244222241 scopus 로고    scopus 로고
    • Prognostic relevance of gene amplifications and coamplifications in breast cancer
    • Al-Kuraya K, Schraml P, Torhorst J, et al. Prognostic relevance of gene amplifications and coamplifications in breast cancer. Cancer Res 2004;64:8534-40.
    • (2004) Cancer Res , vol.64 , pp. 8534-8540
    • Al-Kuraya, K.1    Schraml, P.2    Torhorst, J.3
  • 4
    • 0037738898 scopus 로고    scopus 로고
    • Identifying and validating causal genetic alterations in human breast cancer
    • Ethier SP. Identifying and validating causal genetic alterations in human breast cancer. Breast Cancer Res Treat 2003;78:285-7.
    • (2003) Breast Cancer Res Treat , vol.78 , pp. 285-287
    • Ethier, S.P.1
  • 5
    • 0036214044 scopus 로고    scopus 로고
    • The ErbB receptor family: A therapeutic target for cancer
    • de Bono JS, Rowinsky EK. The ErbB receptor family: a therapeutic target for cancer. Trends Mol Med 2002;8:S19-26.
    • (2002) Trends Mol Med , vol.8
    • de Bono, J.S.1    Rowinsky, E.K.2
  • 6
    • 33745686009 scopus 로고    scopus 로고
    • RNA interference-based functional dissection of the 17q12 amplicon in breast cancer reveals contribution of coamplified genes
    • Kao J, Pollack JR. RNA interference-based functional dissection of the 17q12 amplicon in breast cancer reveals contribution of coamplified genes. Genes Chromosomes Cancer 2006;45:761-9.
    • (2006) Genes Chromosomes Cancer , vol.45 , pp. 761-769
    • Kao, J.1    Pollack, J.R.2
  • 7
    • 33847375227 scopus 로고    scopus 로고
    • Protein-tyrosine phosphatase 1B is required for HER2/Neu-induced breast cancer
    • Bentires-Alj M, Neel BG. Protein-tyrosine phosphatase 1B is required for HER2/Neu-induced breast cancer. Cancer Res 2007;67:2420-4.
    • (2007) Cancer Res , vol.67 , pp. 2420-2424
    • Bentires-Alj, M.1    Neel, B.G.2
  • 8
    • 33847202286 scopus 로고    scopus 로고
    • Protein tyrosine phosphatase 1B deficiency or inhibition delays ErbB2-induced mammary tumorigenesis and protects from lung metastasis
    • Julien SG, Dube N, Read M, et al. Protein tyrosine phosphatase 1B deficiency or inhibition delays ErbB2-induced mammary tumorigenesis and protects from lung metastasis. Nat Genet 2007;39:338-46.
    • (2007) Nat Genet , vol.39 , pp. 338-346
    • Julien, S.G.1    Dube, N.2    Read, M.3
  • 9
    • 0027218571 scopus 로고
    • FGFRI and PLAT genes and DNA amplification at 8p12 in breast and ovarian cancers
    • Theillet C, Adelaide J, Louason G, et al. FGFRI and PLAT genes and DNA amplification at 8p12 in breast and ovarian cancers. Genes Chromosomes Cancer 1993;7:219-26.
    • (1993) Genes Chromosomes Cancer , vol.7 , pp. 219-226
    • Theillet, C.1    Adelaide, J.2    Louason, G.3
  • 10
    • 0031799784 scopus 로고    scopus 로고
    • Chromosome region 8p11-p21: Refined mapping and molecular alterations in breast cancer
    • Adelaide J, Chaffanet M, Imbert A, et al. Chromosome region 8p11-p21: refined mapping and molecular alterations in breast cancer. Genes Chromosomes Cancer 1998;22:186-99.
    • (1998) Genes Chromosomes Cancer , vol.22 , pp. 186-199
    • Adelaide, J.1    Chaffanet, M.2    Imbert, A.3
  • 11
    • 0033545570 scopus 로고    scopus 로고
    • Differential expression assay of chromosome arm 8p genes identifies Frizzled-related (FRP1/FRZB) and fibroblast growth factor receptor 1 (FGFR1) as candidate breast cancer genes
    • Ugolini F, Adelaide J, Charafe-Jauffret E, et al. Differential expression assay of chromosome arm 8p genes identifies Frizzled-related (FRP1/FRZB) and fibroblast growth factor receptor 1 (FGFR1) as candidate breast cancer genes. Oncogene 1999;18:1903-10.
    • (1999) Oncogene , vol.18 , pp. 1903-1910
    • Ugolini, F.1    Adelaide, J.2    Charafe-Jauffret, E.3
  • 12
    • 0035878457 scopus 로고    scopus 로고
    • WHSC1L1, on human chromosome 8p11.2, closely resembles WHSC1 and maps to a duplicated region shared with 4p16.3
    • Stec I, van Ommen GJ, den Dunnen JT. WHSC1L1, on human chromosome 8p11.2, closely resembles WHSC1 and maps to a duplicated region shared with 4p16.3. Genomics 2001;76:5-8.
    • (2001) Genomics , vol.76 , pp. 5-8
    • Stec, I.1    van Ommen, G.J.2    den Dunnen, J.T.3
  • 13
    • 23444453060 scopus 로고    scopus 로고
    • A 1 Mb minimal amplicon at 8p11-12 in breast cancer identifies new candidate oncogenes
    • Garcia MJ, Pole JCM, Chin S-F, et al. A 1 Mb minimal amplicon at 8p11-12 in breast cancer identifies new candidate oncogenes. Oncogene 2005;24:5235-45.
    • (2005) Oncogene , vol.24 , pp. 5235-5245
    • Garcia, M.J.1    Pole, J.C.M.2    Chin, S.-F.3
  • 14
    • 29944447205 scopus 로고    scopus 로고
    • Comprehensive profiling of 8p11-12 amplification in breast cancer
    • Gelsi-Boyer V, Orsetti B, Cervera N, et al. Comprehensive profiling of 8p11-12 amplification in breast cancer. Mol Cancer Res 2005;3:655-67.
    • (2005) Mol Cancer Res , vol.3 , pp. 655-667
    • Gelsi-Boyer, V.1    Orsetti, B.2    Cervera, N.3
  • 15
    • 33846209170 scopus 로고    scopus 로고
    • Multiple interacting oncogenes on the 8p11-12 amplicon in human breast cancer
    • Yang ZQ, Streicher KL, Ray ME, Abrams J, Ethier SP. Multiple interacting oncogenes on the 8p11-12 amplicon in human breast cancer. Cancer Res 2006;66:11632-43.
    • (2006) Cancer Res , vol.66 , pp. 11632-11643
    • Yang, Z.Q.1    Streicher, K.L.2    Ray, M.E.3    Abrams, J.4    Ethier, S.P.5
  • 16
    • 1642535541 scopus 로고    scopus 로고
    • Genomic and expression analysis of the 8p11-12 amplicon in human breast cancer cell lines
    • Ray ME, Yang ZQ, Albertson D, et al. Genomic and expression analysis of the 8p11-12 amplicon in human breast cancer cell lines. Cancer Res 2004;64:40-7.
    • (2004) Cancer Res , vol.64 , pp. 40-47
    • Ray, M.E.1    Yang, Z.Q.2    Albertson, D.3
  • 17
    • 27744586900 scopus 로고    scopus 로고
    • NRG1 gene rearrangements in clinical breast cancer: Identification of an adjacent novel amplicon associated with poor prognosis
    • Prentice LM, Shadeo A, Lestou VS, et al. NRG1 gene rearrangements in clinical breast cancer: identification of an adjacent novel amplicon associated with poor prognosis. Oncogene 2005;24:7281-9.
    • (2005) Oncogene , vol.24 , pp. 7281-7289
    • Prentice, L.M.1    Shadeo, A.2    Lestou, V.S.3
  • 18
    • 33845331706 scopus 로고    scopus 로고
    • FGFR1 emerges as a potential therapeutic target for lobular breast carcinomas
    • Reis-Filho JS, Simpson PT, Turner NC, et al. FGFR1 emerges as a potential therapeutic target for lobular breast carcinomas. Clin Cancer Res 2006;12:6652-62.
    • (2006) Clin Cancer Res , vol.12 , pp. 6652-6662
    • Reis-Filho, J.S.1    Simpson, P.T.2    Turner, N.C.3
  • 19
    • 34047132184 scopus 로고    scopus 로고
    • Transforming function of the LSM1 oncogene in human breast cancers with the 8p11-12 amplicon
    • Streicher KL, Yang ZQ, Draghici S, Ethier SP. Transforming function of the LSM1 oncogene in human breast cancers with the 8p11-12 amplicon. Oncogene 2007;26:2104-14.
    • (2007) Oncogene , vol.26 , pp. 2104-2114
    • Streicher, K.L.1    Yang, Z.Q.2    Draghici, S.3    Ethier, S.P.4
  • 20
    • 0018639079 scopus 로고
    • Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease
    • Chirgwin JM, Przybyla AE, MacDonald RJ, Rutter WJ. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 1979;18:5294-9.
    • (1979) Biochemistry , vol.18 , pp. 5294-5299
    • Chirgwin, J.M.1    Przybyla, A.E.2    MacDonald, R.J.3    Rutter, W.J.4
  • 21
    • 0025105850 scopus 로고    scopus 로고
    • Simultaneous isolation of DNA, RNA, and antigenic protein exhibiting kinase activity from small tumor samples using guanidine isothiocyanate
    • Coombs LM, Pigott D, Proctor A, Eydmann M, Denner J, Knowles MA. Simultaneous isolation of DNA, RNA, and antigenic protein exhibiting kinase activity from small tumor samples using guanidine isothiocyanate. Anal Biochem1990;188:338-43.
    • Anal Biochem1990;188 , pp. 338-343
    • Coombs, L.M.1    Pigott, D.2    Proctor, A.3    Eydmann, M.4    Denner, J.5    Knowles, M.A.6
  • 22
    • 24644519817 scopus 로고    scopus 로고
    • Two types of chromosome 1p losses with opposite significance in gliomas
    • Idbaih A, Marie Y, Pierron G, et al. Two types of chromosome 1p losses with opposite significance in gliomas. Ann Neurol 2005;58:483-7.
    • (2005) Ann Neurol , vol.58 , pp. 483-487
    • Idbaih, A.1    Marie, Y.2    Pierron, G.3
  • 23
    • 13944263929 scopus 로고    scopus 로고
    • Visualizing chromosomes as transcriptome correlation maps: Evidence of chromosomal domains containing co-expressed genes - a study of 130 invasive ductal breast carcinomas
    • Reyal F, Stransky N, Bernard-Pierrot I, et al. Visualizing chromosomes as transcriptome correlation maps: evidence of chromosomal domains containing co-expressed genes - a study of 130 invasive ductal breast carcinomas. Cancer Res 2005;65:1376-83.
    • (2005) Cancer Res , vol.65 , pp. 1376-1383
    • Reyal, F.1    Stransky, N.2    Bernard-Pierrot, I.3
  • 24
    • 3242733298 scopus 로고    scopus 로고
    • Atelocollagen-mediated synthetic small interfering RNA delivery for effective gene silencing in vitro and in vivo
    • Minakuchi Y, Takeshita F, Kosaka N, et al. Atelocollagen-mediated synthetic small interfering RNA delivery for effective gene silencing in vitro and in vivo. Nucleic Acids Res 2004;32:e109.
    • (2004) Nucleic Acids Res , vol.32
    • Minakuchi, Y.1    Takeshita, F.2    Kosaka, N.3
  • 25
    • 35748961127 scopus 로고    scopus 로고
    • Statistical tools for synthesizing lists of differentially expressed features in related experiments
    • Blangiardo M, Richardson S. Statistical tools for synthesizing lists of differentially expressed features in related experiments. Genome Biol 2007;8:R54.
    • (2007) Genome Biol , vol.8
    • Blangiardo, M.1    Richardson, S.2
  • 28
    • 0042121055 scopus 로고    scopus 로고
    • Onto-Tools, the toolkit of the modern biologist: Onto-Express, Onto-Compare, Onto-Design and Onto-Translate
    • Draghici S, Khatri P, Bhavsar P, Shah A, Krawetz SA, Tainsky MA. Onto-Tools, the toolkit of the modern biologist: Onto-Express, Onto-Compare, Onto-Design and Onto-Translate. Nucleic Acids Res 2003;31:3775-81.
    • (2003) Nucleic Acids Res , vol.31 , pp. 3775-3781
    • Draghici, S.1    Khatri, P.2    Bhavsar, P.3    Shah, A.4    Krawetz, S.A.5    Tainsky, M.A.6
  • 30
    • 0037337623 scopus 로고    scopus 로고
    • Assessing the functional bias of commercial microarrays using the onto-compare database
    • Mar
    • Draghici S, Khatri P, Shah A, Tainsky MA. Assessing the functional bias of commercial microarrays using the onto-compare database. Biotechniques 2003;Mar, Suppl:55-61.
    • (2003) Biotechniques , Issue.SUPPL. , pp. 55-61
    • Draghici, S.1    Khatri, P.2    Shah, A.3    Tainsky, M.A.4
  • 31
    • 34548400259 scopus 로고    scopus 로고
    • A systems biology approach for pathway level analysis
    • Draghici S, Khatri P, Tarca AL, et al. A systems biology approach for pathway level analysis. Genome Res 2007;17:1537-45.
    • (2007) Genome Res , vol.17 , pp. 1537-1545
    • Draghici, S.1    Khatri, P.2    Tarca, A.L.3
  • 32
    • 33751373933 scopus 로고    scopus 로고
    • Babel's tower revisited: A universal resource for cross-referencing across annotation databases
    • Draghici S, Sellamuthu S, Khatri P. Babel's tower revisited: a universal resource for cross-referencing across annotation databases. Bioinformatics 2006;22:2934-9.
    • (2006) Bioinformatics , vol.22 , pp. 2934-2939
    • Draghici, S.1    Sellamuthu, S.2    Khatri, P.3
  • 33
    • 3242887152 scopus 로고    scopus 로고
    • Onto-Tools: An ensemble of web-accessible, ontology-based tools for the functional design and interpretation of high-throughput gene expression experiments
    • Khatri P, Bhavsar P, Bawa G, Draghici S. Onto-Tools: an ensemble of web-accessible, ontology-based tools for the functional design and interpretation of high-throughput gene expression experiments. Nucleic Acids Res 2004;32:W449-56.
    • (2004) Nucleic Acids Res , vol.32
    • Khatri, P.1    Bhavsar, P.2    Bawa, G.3    Draghici, S.4
  • 36
    • 0033536197 scopus 로고    scopus 로고
    • Cloning of TACC1, an embryonically expressed, potentially transforming coiled coil containing gene, fromthe 8p11 breast cancer amplicon
    • Still IH, Hamilton M, Vince P, Wolfman A, Cowell JK. Cloning of TACC1, an embryonically expressed, potentially transforming coiled coil containing gene, fromthe 8p11 breast cancer amplicon. Oncogene 1999;18:4032-8.
    • (1999) Oncogene , vol.18 , pp. 4032-4038
    • Still, I.H.1    Hamilton, M.2    Vince, P.3    Wolfman, A.4    Cowell, J.K.5
  • 37
    • 22144433675 scopus 로고    scopus 로고
    • High-resolution genomic profiles of human lung cancer
    • Tonon G, Wong KK, Maulik G, et al. High-resolution genomic profiles of human lung cancer. Proc Natl Acad Sci U S A 2005;102:9625-30.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 9625-9630
    • Tonon, G.1    Wong, K.K.2    Maulik, G.3
  • 38
    • 34548482720 scopus 로고    scopus 로고
    • DUSP22/LMW-DSP2 regulates estrogen receptor-α-mediated signaling through dephosphorylation of Ser-118
    • Sekine Y, Ikeda O, Hayakawa Y, et al. DUSP22/LMW-DSP2 regulates estrogen receptor-α-mediated signaling through dephosphorylation of Ser-118. Oncogene 2007;26:6038-49.
    • (2007) Oncogene , vol.26 , pp. 6038-6049
    • Sekine, Y.1    Ikeda, O.2    Hayakawa, Y.3
  • 39
    • 30344486694 scopus 로고    scopus 로고
    • Bystander effect contributes to the antitumor efficacy of CaSm antisense gene therapy in a preclinical model of advanced pancreatic cancer
    • Yan Y, Rubinchik S, Wood AL, et al. Bystander effect contributes to the antitumor efficacy of CaSm antisense gene therapy in a preclinical model of advanced pancreatic cancer. Mol Ther 2006;13:357-65.
    • (2006) Mol Ther , vol.13 , pp. 357-365
    • Yan, Y.1    Rubinchik, S.2    Wood, A.L.3
  • 40
    • 33645029278 scopus 로고    scopus 로고
    • HTPAP gene on chromosome 8p is a candidate metastasis suppressor for human hepatocellular carcinoma
    • Wu X, Jia HL, Wang YF, et al. HTPAP gene on chromosome 8p is a candidate metastasis suppressor for human hepatocellular carcinoma. Oncogene 2006;25:1832-40.
    • (2006) Oncogene , vol.25 , pp. 1832-1840
    • Wu, X.1    Jia, H.L.2    Wang, Y.F.3
  • 41
    • 0027282044 scopus 로고
    • bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death
    • Boise LH, Gonzalez-Garcia M, Postema CE, et al. bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. Cell 1993;74:597-608.
    • (1993) Cell , vol.74 , pp. 597-608
    • Boise, L.H.1    Gonzalez-Garcia, M.2    Postema, C.E.3
  • 42
    • 7444240784 scopus 로고    scopus 로고
    • Genomic organization of the 8p11-p12 amplicon in three breast cancer cell lines
    • Yang ZQ, Albertson D, Ethier SP. Genomic organization of the 8p11-p12 amplicon in three breast cancer cell lines. Cancer Genet Cytogenet 2004;155:57-62.
    • (2004) Cancer Genet Cytogenet , vol.155 , pp. 57-62
    • Yang, Z.Q.1    Albertson, D.2    Ethier, S.P.3
  • 43
    • 1842591164 scopus 로고    scopus 로고
    • High-resolution analysis of genomic copy number alterations in bladder cancer by microarray-based comparative genomic hybridization
    • Hurst CD, Fiegler H, Carr P, Williams S, Carter NP, Knowles MA. High-resolution analysis of genomic copy number alterations in bladder cancer by microarray-based comparative genomic hybridization. Oncogene 2004;23:2250-63.
    • (2004) Oncogene , vol.23 , pp. 2250-2263
    • Hurst, C.D.1    Fiegler, H.2    Carr, P.3    Williams, S.4    Carter, N.P.5    Knowles, M.A.6
  • 44
    • 33748669269 scopus 로고    scopus 로고
    • High-resolution analysis of chromosome rearrangements on 8p in breast, colon and pancreatic cancer reveals a complex pattern of loss, gain and translocation
    • Pole JCM, Courtay-Cahen C, Garcia MJ, et al. High-resolution analysis of chromosome rearrangements on 8p in breast, colon and pancreatic cancer reveals a complex pattern of loss, gain and translocation. Oncogene 2006;25:5693-706.
    • (2006) Oncogene , vol.25 , pp. 5693-5706
    • Pole, J.C.M.1    Courtay-Cahen, C.2    Garcia, M.J.3
  • 45
    • 0035834386 scopus 로고    scopus 로고
    • A phosphatase associated with metastasis of colorectal cancer
    • Saha S, Bardelli A, Buckhaults P, et al. A phosphatase associated with metastasis of colorectal cancer. Science 2001;294:1343-6.
    • (2001) Science , vol.294 , pp. 1343-1346
    • Saha, S.1    Bardelli, A.2    Buckhaults, P.3
  • 46
    • 0035415662 scopus 로고    scopus 로고
    • Protein tyrosine phosphatases: Prospects for therapeutics
    • Zhang ZY. Protein tyrosine phosphatases: prospects for therapeutics. Curr Opin Chem Biol 2001;5:416-23.
    • (2001) Curr Opin Chem Biol , vol.5 , pp. 416-423
    • Zhang, Z.Y.1
  • 47
    • 33847391938 scopus 로고    scopus 로고
    • A brake becomes an accelerator: PTP1B - a new therapeutic target for breast cancer
    • Tonks NK, Muthuswamy SK. A brake becomes an accelerator: PTP1B - a new therapeutic target for breast cancer. Cancer Cell 2007;11:214-6.
    • (2007) Cancer Cell , vol.11 , pp. 214-216
    • Tonks, N.K.1    Muthuswamy, S.K.2


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