Analysis of breast cancer related gene expression using natural splines and the Cox proportional hazard model to identify prognostic associations

Breast Cancer Research and Treatment

Volumn 122, Issue 3, 2010, Pages 711-720

  Kreike, Bas ^a   Hart, Guus ^a   Bartelink, Harry ^a   Van De Vijver, Marc J ^b  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

Breast cancer; Cox proportional hazard analysis; Distant metastasis free probability; Microarray gene expression data; Natural spline analysis

Indexed keywords

CHEMOKINE RECEPTOR CCR7; CHEMOKINE RECEPTOR CXCR4; CYCLIN D1; CYCLIN E; CYCLIN E1; CYCLIN E2; EMBRYONIC ECTODERM DEVELOPMENT PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR 3; EPIDERMAL GROWTH FACTOR RECEPTOR 4; ESTROGEN RECEPTOR ALPHA; HISTONE LYSINE METHYLTRANSFERASE; PLASMINOGEN ACTIVATOR INHIBITOR 1; STROMAL CELL DERIVED FACTOR 1; UNCLASSIFIED DRUG; UROKINASE; VASCULOTROPIN; TUMOR MARKER;

ARTICLE; BREAST CANCER; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC SCREENING; HUMAN; MAJOR CLINICAL STUDY; MATHEMATICAL MODEL; METHODOLOGY; MICROARRAY ANALYSIS; PRIORITY JOURNAL; PROPORTIONAL HAZARDS MODEL; BREAST NEOPLASMS; COHORT ANALYSIS; DNA MICROARRAY; GENETICS; MIDDLE AGED; NETHERLANDS; PROGNOSIS; REGRESSION ANALYSIS; SECONDARY;

BREAST NEOPLASMS; COHORT STUDIES; FEMALE; GENE EXPRESSION PROFILING; HUMANS; MIDDLE AGED; NETHERLANDS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; REGRESSION ANALYSIS; TUMOR MARKERS, BIOLOGICAL;

EID: 77955551924     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-009-0588-6     Document Type: Article

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