High-fat diet-induced renal cell apoptosis and oxidative stress in spontaneously hypertensive rat are ameliorated by fenofibrate through the PPARα-FoxO3a-PGC-1α pathway

Nephrology Dialysis Transplantation

Volumn 27, Issue 6, 2012, Pages 2213-2225

  Chung, Hyun Wha ^a   Lim, Ji Hee ^a   Kim, Min Young ^a   Shin, Seok Joon ^a   Chung, Sungjin ^a   Choi, Bum Soon ^a   Kim, Hyung Wook ^a   Kim, Yong Soo ^a   Park, Cheol Whee ^a   Chang, Yoon Sik ^a  

^a The Catholic University of Korea   (South Korea)

Author keywords

FoxO3a; Lipotoxicity; Oxidative stress; PGC 1 ; PPAR

Indexed keywords

ESTROGEN RELATED RECEPTOR ALPHA; FATTY ACID; FENOFIBRATE; GLUCOSE; INSULIN; MANGANESE SUPEROXIDE DISMUTASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BCL 2; PROTEIN KINASE B; TEMPOL; TRANSCRIPTION FACTOR FKHRL1; TRIACYLGLYCEROL;

ALBUMINURIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; FATTY ACID BLOOD LEVEL; GLUCOSE INTOLERANCE; INSULIN BLOOD LEVEL; KIDNEY CELL; LIPID DIET; MALE; NEPHRITIS; NONHUMAN; OXIDATIVE STRESS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS INHIBITION; RAT; RENAL PROTECTION; RENOVASCULAR HYPERTENSION; SIGNAL TRANSDUCTION; SPONTANEOUSLY HYPERTENSIVE RAT; SYSTOLIC BLOOD PRESSURE; TRIACYLGLYCEROL BLOOD LEVEL; WISTAR KYOTO RAT;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; DIET, HIGH-FAT; FENOFIBRATE; FORKHEAD TRANSCRIPTION FACTORS; HYPOLIPIDEMIC AGENTS; IMMUNOENZYME TECHNIQUES; KIDNEY DISEASES; MALE; OXIDATIVE STRESS; PHOSPHORYLATION; PPAR ALPHA; RATS; RATS, INBRED SHR; RATS, INBRED WKY; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA-BINDING PROTEINS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS;

EID: 84858343166     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfr613     Document Type: Article

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