Distal regulatory elements are required for Fshr expression, in vivo

Molecular and Cellular Endocrinology

Volumn 260-262, Issue , 2007, Pages 49-58

  Hermann, Brian P ^a   Hornbaker, Kaori I ^a   Maran, Rengasamy R M ^a   Heckert, Leslie L ^a  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

Author keywords

Comparative genomics; Fshr; Sertoli cell; Transgenics; Yeast artificial chromosome

Indexed keywords

FOLLITROPIN RECEPTOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; GENETIC CONSERVATION; GENETIC TRANSFECTION; GENOMICS; GERM CELL; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SERTOLI CELL; TESTIS; TRANSGENE; TRANSGENIC MOUSE; YEAST ARTIFICIAL CHROMOSOME;

ANIMALS; BASE SEQUENCE; CHROMOSOME MAPPING; CHROMOSOMES, ARTIFICIAL, YEAST; CONSERVED SEQUENCE; EVOLUTION, MOLECULAR; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; INTEGRASES; MICE; MICE, TRANSGENIC; RATS; RECEPTORS, FSH; RECOMBINATION, GENETIC; REGULATORY SEQUENCES, NUCLEIC ACID; RNA, MESSENGER; SACCHAROMYCES CEREVISIAE; TRANSCRIPTION, GENETIC;

EID: 33751210936     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mce.2006.01.017     Document Type: Article

References (45)

1. Baroukh N., Ahituv N., Chang J., Shoukry M., Afzal V., Rubin E.M., and Pennacchio L.A. Comparative genomic analysis reveals a distant liver enhancer upstream of the COUP-TFII gene. Mamm. Genome 16 (2005) 91-95
2. Bishop C.E., Whitworth D.J., Qin Y., Agoulnik A.I., Agoulnik I.U., Harrison W.R., Behringer R.R., and Overbeek P.A. A transgenic insertion upstream of sox9 is associated with dominant XX sex reversal in the mouse. Nat. Genet. 26 (2000) 490-494
3. Camp T.A., Rahal J.O., and Mayo K.E. Cellular localization and hormonal regulation of follicle-stimulating hormone and luteinizaing hormone receptor messenger RNAs in the rat ovary. Mol. Endocrinol. 5 (1991) 1405-1417
4. Frazer K.A., Elnitski L., Church D.M., Dubchak I., and Hardison R.C. Cross-species sequence comparisons: a review of methods and available resources. Genome Res. 13 (2003) 1-12
5. Giraldo P., and Montoliu L. Size matters: use of YACs, BACs and PACs in transgenic animals. Transgenic Res. 10 (2001) 83-103
6. Goetz T.L., Lloyd T.L., and Griswold M.D. Role of E box and initiatory region in the expression of the rat Follicle-stimulating hormone receptor. J. Biol. Chem. 271 (1996) 33317-33324
7. Gottgens B., et al. Analysis of vertebrate SCL loci identifies conserved enhancers. Nat. Biotechnol. 18 (2000) 181-186
8. Green E.D., Hieter P., and Spencer F.A. Yeast artificial chromosomes. In: Birren B., et al. (Ed). Genome Analysis; A Laboratory Manual (1997), Cold Spring Harbor Laboratory Press, Plainview 297-565
9. Gromoll J., Dankbar B., and Gudermann T. Characterization of the 5′ flanking region of the human Follicle-stimulating hormone receptor gene. Mol. Cell. Endocrinol. 102 (1994) 93-102
10. Heckert L.L. Structure and regulation of the FSH Receptor gene. In: Skinner M.K., and Griswold M.D. (Eds). Sertoli Cell Biology (2005), Elsevier Academic Press, San Diego, CA 281-302
11. Heckert L.L. Activation of the rat Follicle-stimulating hormone receptor promoter by steroidogenic factor 1 is blocked by protein kinase a and requires upstream stimulatory factor binding to a proximal E-box element. Mol. Endocrinol. 15 (2001) 704-715
12. Heckert L.L., Daggett M.A., and Chen J. Multiple promoter elements contribute to activity of the Follicle-stimulating hormone receptor (FSHR) gene in testicular Sertoli cells. Mol. Endocrinol. 12 (1998) 1499-1512
13. Heckert L.L., and Griswold M.D. The expression of the follicle-stimulating hormone receptor in spermatogenesis. Recent Prog. Horm. Res. 57 (2002) 129-148
14. Heckert L.L., Sawadogo M., Daggett M.A., and Chen J. The USF proteins regulate transcription of the Follicle-stimulating hormone receptor but are insufficient for cell-specific expression. Mol. Endocrinol. 14 (2000) 1836-1848
15. Hermann B.P., and Heckert L.L. Silencing of Fshr occurs through a conserved, hypersensitive site in the first intron. Mol. Endocrinol. 19 (2005) 2112-2131
16. Huhtaniemi I., Eskola V., Pakarinen P., Matikainen T., and Sprengel R. The murine Luteinizing hormone and Follicle-stimulating hormone receptor genes: transcripional initiation sites, putative promoter sequences, and promoter activity. Mol. Cell. Endocrinol. 88 (1992) 55-66
17. Karpova T., Presley J., Manimaran R.R., Scherrer S.P., Tejada L., Peterson K.R., and Heckert L.L. A Ftz-F1-containing yeast artificial chromosome recapitulates expression of steroidogenic factor 1 in vivo. Mol. Endocrinol. (2005)
18. Lettice L.A., et al. Disruption of a long-range cis-acting regulator for Shh causes preaxial polydactyly. Proc. Natl. Acad. Sci. U.S.A. 99 (2002) 7548-7553
19. Levallet J., Koskimies P., Rahman N., and Huhtaniemi I. The promoter of murine Follicle-stimulating hormone receptor: functional characterization and regulation by transcription factor steroidogenic factor 1. Mol. Endocrinol. 15 (2001) 80-92
20. Linder C.C., Heckert L.L., Goetz T.L., and Griswold M.D. Follicle-stimulating hormone receptor gene promoter activity. Endocrine 2 (1994) 957-966
21. Loots G.G., Locksley R.M., Blankespoor C.M., Wang Z.E., Miller W., Rubin E.M., and Frazer K.A. Identification of a coordinate regulator of interleukins 4,13 and 5 by cross-species sequence comparisons. Science 288 (2000) 136-140
22. Navas P.A., Peterson K.R., Li Q., McArthur M., and Stamatoyannopoulos G. The 5′HS4 core element of the human beta-globin locus control region is required for high-level globin gene expression in definitive but not in primitive erythropoiesis. J. Mol. Biol. 312 (2001) 17-26
23. Nobrega M.A., Ovcharenko I., Afzal V., and Rubin E.M. Scanning human gene deserts for long-range enhancers. Science 302 (2003) 413
24. Nordhoff V., Gromoll J., Foppiani L., Luetjens C.M., Schlatt S., Kostova E., Huhtaniemi I., Nieschlag E., and Simoni M. Targeted expression of human FSH receptor Asp567Gly mutant mRNA in testis of transgenic mice: role of human FSH receptor promoter. Asian J. Androl. 5 (2003) 267-275
25. Novak A., Guo C., Yang W., Nagy A., and Lobe C.G. Z/EG, a double reporter mouse line that expresses enhanced green fluorescent protein upon Cre-mediated excision. Genesis 28 (2000) 147-155
26. Ovcharenko I., Loots G.G., Nobrega M.A., Hardison R.C., Miller W., and Stubbs L. Evolution and functional classification of vertebrate gene deserts. Genome Res. 15 (2005) 137-145
27. Ovcharenko I., Nobrega M.A., Loots G.G., and Stubbs L. ECR Browser: a tool for visualizing and accessing data from comparisons of multiple vertebrate genomes. Nucl. Acids Res. 32 (2004) W280-W286
28. Peterson K.R., Li Q.L., Clegg C.H., Furukawa T., Navas P.A., Norton E.J., Kimbrough T.G., and Stamatoyannopoulos G. Use of yeast artificial chromosomes (YACs) in studies of mammalian development: production of beta-globin locus YAC mice carrying human globin developmental mutants. Proc. Natl. Acad. Sci. U.S.A. 92 (1995) 5655-5659
29. Qin Y., Kong L.K., Poirier C., Truong C., Overbeek P.A., and Bishop C.E. Long-range activation of Sox9 in Odd Sex (Ods) mice. Hum. Mol. Genet. 13 (2004) 1213-1218
30. Rannikki A.S., Zhang F.-P., and Huhtaniemi I.T. Ontogeny of Follicle-stimulating hormone receptor gene expression in the rat testis and ovary. Mol. Cell. Endocrinol. 107 (1995) 199-210
31. Riethman H., Birren B., and Gnirke A. Preparation, manipulation, and mapping of HMW DNA. In: Birren B., et al. (Ed). Genome Analysis; A Laboratory Manual (1997), Cold Spring Harbor Laboratory Press, Plainview 83-248
32. Sagai T., Hosoya M., Mizushina Y., Tamura M., and Shiroishi T. Elimination of a long-range cis-regulatory module causes complete loss of limb-specific Shh expression and truncation of the mouse limb. Development 132 (2005) 797-803
33. Sairam M.R., and Subbarayan V.S.R. Characterization of the 5′ flanking region and potential control elements of the ovine Follitropin receptor gene. Mol. Reprod. Dev. 48 (1997) 480-487
34. Sauer B. Inducible gene targeting in mice using the Cre/lox system. Methods 14 (1998) 381-392
35. Sauer B., and Henderson N. Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1. Proc. Natl. Acad. Sci. U.S.A. 85 (1988) 5166-5170
36. Simoni M., Gromoll J., and Nieschlag E. The Follicle-stimulating hormone receptor: biochemistry, molecular biology, physiology, and pathophysiology. Endocr. Rev. 18 (1997) 739-773
37. Soriano P. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat. Genet. 21 (1999) 70-71
38. Themmen A.P.N., and Huhtaniemi I.T. Mutations of gonadotropins and gonadotropin receptors: elucidating the physiology and pathophysiology of pituitary-gonadal function. Endocr. Rev. 21 (2000) 551-583
39. Tilly J.L., LaPolt P.S., and Hsueh A.J. Hormonal regulation of Follicle-stimulating hormone receptor messenger ribonucleic acid levels in cultured rat granulosa cells. Endocrinology 130 (1992) 1296-1302
40. Tisdall D.J., Watanabe K., Hudson N.L., Smith P., and McNatty K.P. FSH receptor gene expression during ovarian follicle development in sheep. J. Mol. Endocrinol. 15 (1995) 273-281
41. Val P., Lefrancois-Martinez A.M., Veyssiere G., and Martinez A. SF-1 a key player in the development and differentiation of steroidogenic tissues. Nucl. Recept. 1 (2003) 1-8
42. Xing W., Danilovich N., and Sairam M.R. Orphan receptor chicken ovalbumin upstream promoter transcription factors inhibit steroid factor-1, upstream stimulatory factor, and activator protein-1 activation of ovine Follicle-stimulating hormone receptor expression via composite cis-elements. Biol. Reprod. 66 (2002) 1656-1666
43. Xing W., and Sairam M.R. Characterization of regulatory elements of ovine Follicle-stimulating hormone (FSH) receptor gene: the role of E-box in the regulation of ovine FSH receptor expression. Biol. Reprod. 64 (2001) 579-589
44. Zheng P., Pennacchio L.A., Le Goff W., Rubin E.M., and Smith J.D. Identification of a novel enhancer of brain expression near the apoE gene cluster by comparative genomics. Biochim. Biophys. Acta 1676 (2004) 41-50
45. Zhong T.P., Kaphingst K., Akella U., Haldi M., Lander E.S., and Fishman M.C. Zebrafish genomic library in yeast artificial chromosomes. Genomics 48 (1998) 136-138