-
1
-
-
77951212625
-
Src-induced tyrosine phosphorylation of VE-cadherin is not sufficient to decrease barrier function of endothelial monolayers
-
Adam A.P., Sharenko A.L., Pumiglia K., Vincent P.A. Src-induced tyrosine phosphorylation of VE-cadherin is not sufficient to decrease barrier function of endothelial monolayers. J. Biol. Chem. 2010, 285:7045-7055.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 7045-7055
-
-
Adam, A.P.1
Sharenko, A.L.2
Pumiglia, K.3
Vincent, P.A.4
-
2
-
-
60149095737
-
Metabotropic glutamate receptor-dependent long-term potentiation
-
Anwyl R. Metabotropic glutamate receptor-dependent long-term potentiation. Neuropharmacology 2009, 56:735-740.
-
(2009)
Neuropharmacology
, vol.56
, pp. 735-740
-
-
Anwyl, R.1
-
3
-
-
80051891527
-
Hyperhomocysteinemia increases permeability of the blood-brain barrier by NMDA receptor-dependent regulation of adherens and tight junctions
-
Beard R.S., Reynolds J.J., Bearden S.E. Hyperhomocysteinemia increases permeability of the blood-brain barrier by NMDA receptor-dependent regulation of adherens and tight junctions. Blood 2011, 118:2007-2014.
-
(2011)
Blood
, vol.118
, pp. 2007-2014
-
-
Beard, R.S.1
Reynolds, J.J.2
Bearden, S.E.3
-
4
-
-
78249269178
-
Extracellular transsulfuration generates hydrogen sulfide from homocysteine and protects endothelium from redox stress
-
Bearden S.E., Beard R.S., Pfau J.C. Extracellular transsulfuration generates hydrogen sulfide from homocysteine and protects endothelium from redox stress. Am. J. Physiol. Heart Circ. Physiol. 2010, 299:H1568-H1576.
-
(2010)
Am. J. Physiol. Heart Circ. Physiol.
, vol.299
-
-
Bearden, S.E.1
Beard, R.S.2
Pfau, J.C.3
-
5
-
-
0036224169
-
Homocysteine induces protein kinase C activation and stimulates c-Fos and lipoprotein lipase expression in macrophages
-
Beauchamp M.C., Renier G. Homocysteine induces protein kinase C activation and stimulates c-Fos and lipoprotein lipase expression in macrophages. Diabetes 2002, 51:1180-1187.
-
(2002)
Diabetes
, vol.51
, pp. 1180-1187
-
-
Beauchamp, M.C.1
Renier, G.2
-
6
-
-
70249108404
-
Oxidative stress upregulates the NMDA receptor on cerebrovascular endothelium
-
Betzen C., White R., Zehendner C.M., Pietrowski E., Bender B., Luhmann H.J., Kuhlmann C.R. Oxidative stress upregulates the NMDA receptor on cerebrovascular endothelium. Free Radic. Biol. Med. 2009, 47:1212-1220.
-
(2009)
Free Radic. Biol. Med.
, vol.47
, pp. 1212-1220
-
-
Betzen, C.1
White, R.2
Zehendner, C.M.3
Pietrowski, E.4
Bender, B.5
Luhmann, H.J.6
Kuhlmann, C.R.7
-
7
-
-
34347335713
-
Homocysteine and its derivatives as possible modulators of neuronal and non-neuronal cell glutamate receptors in Alzheimer's disease
-
Boldyrev A.A., Johnson P. Homocysteine and its derivatives as possible modulators of neuronal and non-neuronal cell glutamate receptors in Alzheimer's disease. J. Alzheimers Dis. 2007, 11:219-228.
-
(2007)
J. Alzheimers Dis.
, vol.11
, pp. 219-228
-
-
Boldyrev, A.A.1
Johnson, P.2
-
8
-
-
0029066299
-
A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes
-
Boushey C.J., Beresford S.A., Omenn G.S., Motulsky A.G. A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes. JAMA 1995, 274:1049-1057.
-
(1995)
JAMA
, vol.274
, pp. 1049-1057
-
-
Boushey, C.J.1
Beresford, S.A.2
Omenn, G.S.3
Motulsky, A.G.4
-
10
-
-
0141768242
-
The conditional inactivation of the beta-catenin gene in endothelial cells causes a defective vascular pattern and increased vascular fragility
-
Cattelino A., Liebner S., Gallini R., Zanetti A., Balconi G., Corsi A., Bianco P., Wolburg H., Moore R., Oreda B., Kemler R., Dejana E. The conditional inactivation of the beta-catenin gene in endothelial cells causes a defective vascular pattern and increased vascular fragility. J. Cell Biol. 2003, 162:1111-1122.
-
(2003)
J. Cell Biol.
, vol.162
, pp. 1111-1122
-
-
Cattelino, A.1
Liebner, S.2
Gallini, R.3
Zanetti, A.4
Balconi, G.5
Corsi, A.6
Bianco, P.7
Wolburg, H.8
Moore, R.9
Oreda, B.10
Kemler, R.11
Dejana, E.12
-
11
-
-
33744958556
-
Activity-dependent synaptic Wnt release regulates hippocampal long term potentiation
-
Chen J., Park C.S., Tang S.J. Activity-dependent synaptic Wnt release regulates hippocampal long term potentiation. J. Biol. Chem. 2006, 281:11910-11916.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 11910-11916
-
-
Chen, J.1
Park, C.S.2
Tang, S.J.3
-
12
-
-
79951801967
-
MGluR5 positive modulators both potentiate activation and restore inhibition in NMDA receptors by PKC dependent pathway
-
Chen H.H., Liao P.F., Chan M.H. mGluR5 positive modulators both potentiate activation and restore inhibition in NMDA receptors by PKC dependent pathway. J. Biomed. Sci. 2011, 18:19.
-
(2011)
J. Biomed. Sci.
, vol.18
, pp. 19
-
-
Chen, H.H.1
Liao, P.F.2
Chan, M.H.3
-
13
-
-
84858161561
-
Homocysteine impairs endothelial wound healing by activating metabotropic glutamate receptor 5
-
doi:10.1111/j.1549-8719.2012.00159.x, in press. PMID: 22221504.
-
Chen, C.H., Beard Jr., R.S., Bearden, S.E., in press. Homocysteine impairs endothelial wound healing by activating metabotropic glutamate receptor 5. Microcirculation. doi:, PMID: 22221504. doi:10.1111/j.1549-8719.2012.00159.x.
-
Microcirculation.
-
-
Chen, C.H.1
Beard Jr, R.S.2
Bearden, S.E.3
-
14
-
-
33746808398
-
Wnt/beta-catenin signaling in development and disease
-
Clevers H. Wnt/beta-catenin signaling in development and disease. Cell 2006, 127:469-480.
-
(2006)
Cell
, vol.127
, pp. 469-480
-
-
Clevers, H.1
-
15
-
-
0037177827
-
Neutrophil-derived glutamate regulates vascular endothelial barrier function
-
Collard C.D., Park K.A., Montalto M.C., Alapati S., Buras J.A., Stahl G.L., Colgan S.P. Neutrophil-derived glutamate regulates vascular endothelial barrier function. J. Biol. Chem. 2002, 277:14801-14811.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 14801-14811
-
-
Collard, C.D.1
Park, K.A.2
Montalto, M.C.3
Alapati, S.4
Buras, J.A.5
Stahl, G.L.6
Colgan, S.P.7
-
16
-
-
77955977167
-
The Wnt/beta-catenin pathway modulates vascular remodeling and specification by upregulating Dll4/Notch signaling
-
Corada M., Nyqvist D., Orsenigo F., Caprini A., Giampietro C., Taketo M.M., Iruela-Arispe M.L., Adams R.H., Dejana E. The Wnt/beta-catenin pathway modulates vascular remodeling and specification by upregulating Dll4/Notch signaling. Dev. Cell 2010, 18:938-949.
-
(2010)
Dev. Cell
, vol.18
, pp. 938-949
-
-
Corada, M.1
Nyqvist, D.2
Orsenigo, F.3
Caprini, A.4
Giampietro, C.5
Taketo, M.M.6
Iruela-Arispe, M.L.7
Adams, R.H.8
Dejana, E.9
-
17
-
-
0032966912
-
Competitive antagonism of the mouse 5-hydroxytryptamine3 receptor by bisindolylmaleimide I, a "selective" protein kinase C inhibitor
-
Coultrap S.J., Sun H., Tenner T.E., Machu T.K. Competitive antagonism of the mouse 5-hydroxytryptamine3 receptor by bisindolylmaleimide I, a "selective" protein kinase C inhibitor. J. Pharmacol. Exp. Ther. 1999, 290:76-82.
-
(1999)
J. Pharmacol. Exp. Ther.
, vol.290
, pp. 76-82
-
-
Coultrap, S.J.1
Sun, H.2
Tenner, T.E.3
Machu, T.K.4
-
18
-
-
78149456928
-
The mouse blood-brain barrier transcriptome: a new resource for understanding the development and function of brain endothelial cells
-
Daneman R., Zhou L., Agalliu D., Cahoy J.D., Kaushal A., Barres B.A. The mouse blood-brain barrier transcriptome: a new resource for understanding the development and function of brain endothelial cells. PLoS One 2010, 5:e13741.
-
(2010)
PLoS One
, vol.5
-
-
Daneman, R.1
Zhou, L.2
Agalliu, D.3
Cahoy, J.D.4
Kaushal, A.5
Barres, B.A.6
-
19
-
-
57749206415
-
Breaking the VE-cadherin bonds
-
Gavard J. Breaking the VE-cadherin bonds. FEBS Lett. 2009, 583:1-6.
-
(2009)
FEBS Lett.
, vol.583
, pp. 1-6
-
-
Gavard, J.1
-
20
-
-
0038102462
-
Expression of metabotropic glutamate receptors in rat meningeal and brain microvasculature and choroid plexus
-
Gillard S.E., Tzaferis J., Tsui H.C., Kingston A.E. Expression of metabotropic glutamate receptors in rat meningeal and brain microvasculature and choroid plexus. J. Comp. Neurol. 2003, 461:317-332.
-
(2003)
J. Comp. Neurol.
, vol.461
, pp. 317-332
-
-
Gillard, S.E.1
Tzaferis, J.2
Tsui, H.C.3
Kingston, A.E.4
-
21
-
-
51149118892
-
Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of beta-catenin in mice
-
Grigoryan T., Wend P., Klaus A., Birchmeier W. Deciphering the function of canonical Wnt signals in development and disease: conditional loss- and gain-of-function mutations of beta-catenin in mice. Genes Dev. 2008, 22:2308-2341.
-
(2008)
Genes Dev.
, vol.22
, pp. 2308-2341
-
-
Grigoryan, T.1
Wend, P.2
Klaus, A.3
Birchmeier, W.4
-
22
-
-
0034820627
-
Gene targeting reveals a role for the glutamate receptors mGluR5 and GluR2 in learning and memory
-
Jia Z., Lu Y.M., Agopyan N., Roder J. Gene targeting reveals a role for the glutamate receptors mGluR5 and GluR2 in learning and memory. Physiol. Behav. 2001, 73:793-802.
-
(2001)
Physiol. Behav.
, vol.73
, pp. 793-802
-
-
Jia, Z.1
Lu, Y.M.2
Agopyan, N.3
Roder, J.4
-
24
-
-
0032029102
-
Sulphur-containing amino acids are agonists for group 1 metabotropic receptors expressed in clonal RGT cell lines
-
Kingston A.E., Lowndes J., Evans N., Clark B., Tomlinson R., Burnett J.P., Mayne N.G., Cockerham S.L., Lodge D. Sulphur-containing amino acids are agonists for group 1 metabotropic receptors expressed in clonal RGT cell lines. Neuropharmacology 1998, 37:277-287.
-
(1998)
Neuropharmacology
, vol.37
, pp. 277-287
-
-
Kingston, A.E.1
Lowndes, J.2
Evans, N.3
Clark, B.4
Tomlinson, R.5
Burnett, J.P.6
Mayne, N.G.7
Cockerham, S.L.8
Lodge, D.9
-
25
-
-
0034757198
-
Modulation of ionotropic glutamate receptor channels
-
Koles L., Wirkner K., Illes P. Modulation of ionotropic glutamate receptor channels. Neurochem. Res. 2001, 26:925-932.
-
(2001)
Neurochem. Res.
, vol.26
, pp. 925-932
-
-
Koles, L.1
Wirkner, K.2
Illes, P.3
-
26
-
-
0032534703
-
Expression of glutamate receptors on cultured cerebral endothelial cells
-
Krizbai I.A., Deli M.A., Pestenacz A., Siklos L., Szabo C.A., Andras I., Joo F. Expression of glutamate receptors on cultured cerebral endothelial cells. J. Neurosci. Res. 1998, 54:814-819.
-
(1998)
J. Neurosci. Res.
, vol.54
, pp. 814-819
-
-
Krizbai, I.A.1
Deli, M.A.2
Pestenacz, A.3
Siklos, L.4
Szabo, C.A.5
Andras, I.6
Joo, F.7
-
27
-
-
0035092461
-
The metabotropic glutamate receptor system protects against ischemic free radical programmed cell death in rat brain endothelial cells
-
Lin S.H., Maiese K. The metabotropic glutamate receptor system protects against ischemic free radical programmed cell death in rat brain endothelial cells. J. Cereb. Blood Flow Metab. 2001, 21:262-275.
-
(2001)
J. Cereb. Blood Flow Metab.
, vol.21
, pp. 262-275
-
-
Lin, S.H.1
Maiese, K.2
-
28
-
-
0030915272
-
Neurotoxicity associated with dual actions of homocysteine at the N-methyl-d-aspartate receptor
-
Lipton S.A., Kim W.K., Choi Y.B., Kumar S., D'Emilia D.M., Rayudu P.V., Arnelle D.R., Stamler J.S. Neurotoxicity associated with dual actions of homocysteine at the N-methyl-d-aspartate receptor. Proc. Natl. Acad. Sci. U. S. A. 1997, 94:5923-5928.
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 5923-5928
-
-
Lipton, S.A.1
Kim, W.K.2
Choi, Y.B.3
Kumar, S.4
D'Emilia, D.M.5
Rayudu, P.V.6
Arnelle, D.R.7
Stamler, J.S.8
-
29
-
-
4644222902
-
Effects of metabotropic glutamate receptor stimulation on blood-brain barrier permeability during focal cerebral ischemia
-
Liu X., Chi O.Z., Weiss H.R. Effects of metabotropic glutamate receptor stimulation on blood-brain barrier permeability during focal cerebral ischemia. Neurochem. Res. 2004, 29:1857-1862.
-
(2004)
Neurochem. Res.
, vol.29
, pp. 1857-1862
-
-
Liu, X.1
Chi, O.Z.2
Weiss, H.R.3
-
30
-
-
78650512464
-
Effects of blockade of ionotropic glutamate receptors on blood-brain barrier disruption in focal cerebral ischemia
-
Liu X., Hunter C., Weiss H.R., Chi O.Z. Effects of blockade of ionotropic glutamate receptors on blood-brain barrier disruption in focal cerebral ischemia. Neurol. Sci. 2010, 31:699-703.
-
(2010)
Neurol. Sci.
, vol.31
, pp. 699-703
-
-
Liu, X.1
Hunter, C.2
Weiss, H.R.3
Chi, O.Z.4
-
31
-
-
33645777279
-
Homocysteine trials - clear outcomes for complex reasons
-
Loscalzo J. Homocysteine trials - clear outcomes for complex reasons. N. Engl. J. Med. 2006, 354:1629-1632.
-
(2006)
N. Engl. J. Med.
, vol.354
, pp. 1629-1632
-
-
Loscalzo, J.1
-
32
-
-
67650753876
-
The treatment of hyperhomocysteinemia
-
Maron B.A., Loscalzo J. The treatment of hyperhomocysteinemia. Annu. Rev. Med. 2009, 60:39-54.
-
(2009)
Annu. Rev. Med.
, vol.60
, pp. 39-54
-
-
Maron, B.A.1
Loscalzo, J.2
-
33
-
-
84860457412
-
Nitrative stress in cerebral endothelium is mediated by mGluR5 in hyperhomocysteinemia
-
PMID: 22186670
-
Mayo J.N., Beard R.S., Price T.O., Chen C.H., Erickson M.A., Ercal N., Banks W.A., Bearden S.E. Nitrative stress in cerebral endothelium is mediated by mGluR5 in hyperhomocysteinemia. J. Cereb. Blood Flow Metab 2011, PMID: 22186670. 10.1038/jcbfm.2011.185.
-
(2011)
J. Cereb. Blood Flow Metab
-
-
Mayo, J.N.1
Beard, R.S.2
Price, T.O.3
Chen, C.H.4
Erickson, M.A.5
Ercal, N.6
Banks, W.A.7
Bearden, S.E.8
-
34
-
-
0025063772
-
Increased proteolytic activity is responsible for the aberrant morphogenetic behavior of endothelial cells expressing the middle T oncogene
-
Montesano R., Pepper M.S., Mohle-Steinlein U., Risau W., Wagner E.F., Orci L. Increased proteolytic activity is responsible for the aberrant morphogenetic behavior of endothelial cells expressing the middle T oncogene. Cell 1990, 62:435-445.
-
(1990)
Cell
, vol.62
, pp. 435-445
-
-
Montesano, R.1
Pepper, M.S.2
Mohle-Steinlein, U.3
Risau, W.4
Wagner, E.F.5
Orci, L.6
-
35
-
-
0032913183
-
Homocysteine: an emerging age-related cardiovascular risk factor
-
44-46, 49-51
-
Moustapha A., Robinson K. Homocysteine: an emerging age-related cardiovascular risk factor. Geriatrics 1999, 54:41. 44-46, 49-51.
-
(1999)
Geriatrics
, vol.54
, pp. 41
-
-
Moustapha, A.1
Robinson, K.2
-
36
-
-
0036674284
-
Tyrosine phosphorylation of vascular endothelial cadherin and the regulation of microvascular permeability
-
Nwariaku F.E., Liu Z., Zhu X., Turnage R.H., Sarosi G.A., Terada L.S. Tyrosine phosphorylation of vascular endothelial cadherin and the regulation of microvascular permeability. Surgery 2002, 132:180-185.
-
(2002)
Surgery
, vol.132
, pp. 180-185
-
-
Nwariaku, F.E.1
Liu, Z.2
Zhu, X.3
Turnage, R.H.4
Sarosi, G.A.5
Terada, L.S.6
-
37
-
-
0037313972
-
Ionotropic glutamate receptors in cerebral microvascular endothelium are functionally linked to heme oxygenase
-
Parfenova H., Fedinec A., Leffler C.W. Ionotropic glutamate receptors in cerebral microvascular endothelium are functionally linked to heme oxygenase. J. Cereb. Blood Flow Metab. 2003, 23:190-197.
-
(2003)
J. Cereb. Blood Flow Metab.
, vol.23
, pp. 190-197
-
-
Parfenova, H.1
Fedinec, A.2
Leffler, C.W.3
-
38
-
-
43749083302
-
Direct interaction enables cross-talk between ionotropic and group I metabotropic glutamate receptors
-
Perroy J., Raynaud F., Homburger V., Rousset M.C., Telley L., Bockaert J., Fagni L. Direct interaction enables cross-talk between ionotropic and group I metabotropic glutamate receptors. J. Biol. Chem. 2008, 283:6799-6805.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 6799-6805
-
-
Perroy, J.1
Raynaud, F.2
Homburger, V.3
Rousset, M.C.4
Telley, L.5
Bockaert, J.6
Fagni, L.7
-
39
-
-
0028912822
-
The metabotropic glutamate receptors: structure and functions
-
Pin J.P., Duvoisin R. The metabotropic glutamate receptors: structure and functions. Neuropharmacology 1995, 34:1-26.
-
(1995)
Neuropharmacology
, vol.34
, pp. 1-26
-
-
Pin, J.P.1
Duvoisin, R.2
-
40
-
-
24744449317
-
Tyrosine phosphorylation of VE-cadherin prevents binding of p120- and beta-catenin and maintains the cellular mesenchymal state
-
Potter M.D., Barbero S., Cheresh D.A. Tyrosine phosphorylation of VE-cadherin prevents binding of p120- and beta-catenin and maintains the cellular mesenchymal state. J. Biol. Chem. 2005, 280:31906-31912.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 31906-31912
-
-
Potter, M.D.1
Barbero, S.2
Cheresh, D.A.3
-
41
-
-
77949710746
-
The NR1 subunit of NMDA receptor regulates monocyte transmigration through the brain endothelial cell barrier
-
Reijerkerk A., Kooij G., van der Pol S.M., Leyen T., Lakeman K., van Het Hof B., Vivien D., de Vries H.E. The NR1 subunit of NMDA receptor regulates monocyte transmigration through the brain endothelial cell barrier. J. Neurochem. 2010, 113:447-453.
-
(2010)
J. Neurochem.
, vol.113
, pp. 447-453
-
-
Reijerkerk, A.1
Kooij, G.2
van der Pol, S.M.3
Leyen, T.4
Lakeman, K.5
van Het Hof, B.6
Vivien, D.7
de Vries, H.E.8
-
42
-
-
77953618742
-
Functional interaction of metabotropic glutamate receptor 5 and NMDA-receptor by a metabotropic glutamate receptor 5 positive allosteric modulator
-
Rosenbrock H., Kramer G., Hobson S., Koros E., Grundl M., Grauert M., Reymann K.G., Schroder U.H. Functional interaction of metabotropic glutamate receptor 5 and NMDA-receptor by a metabotropic glutamate receptor 5 positive allosteric modulator. Eur. J. Pharmacol. 2010, 639:40-46.
-
(2010)
Eur. J. Pharmacol.
, vol.639
, pp. 40-46
-
-
Rosenbrock, H.1
Kramer, G.2
Hobson, S.3
Koros, E.4
Grundl, M.5
Grauert, M.6
Reymann, K.G.7
Schroder, U.H.8
-
43
-
-
33845199344
-
Glutamate-stimulated peroxynitrite production in a brain-derived endothelial cell line is dependent on N-methyl-d-aspartate (NMDA) receptor activation
-
Scott G.S., Bowman S.R., Smith T., Flower R.J., Bolton C. Glutamate-stimulated peroxynitrite production in a brain-derived endothelial cell line is dependent on N-methyl-d-aspartate (NMDA) receptor activation. Biochem. Pharmacol. 2007, 73:228-236.
-
(2007)
Biochem. Pharmacol.
, vol.73
, pp. 228-236
-
-
Scott, G.S.1
Bowman, S.R.2
Smith, T.3
Flower, R.J.4
Bolton, C.5
-
44
-
-
0037075257
-
Plasma homocysteine as a risk factor for dementia and Alzheimer's disease
-
Seshadri S., Beiser A., Selhub J., Jacques P.F., Rosenberg I.H., D'Agostino R.B., Wilson P.W., Wolf P.A. Plasma homocysteine as a risk factor for dementia and Alzheimer's disease. N. Engl. J. Med. 2002, 346:476-483.
-
(2002)
N. Engl. J. Med.
, vol.346
, pp. 476-483
-
-
Seshadri, S.1
Beiser, A.2
Selhub, J.3
Jacques, P.F.4
Rosenberg, I.H.5
D'Agostino, R.B.6
Wilson, P.W.7
Wolf, P.A.8
-
45
-
-
2642574368
-
Human neuroepithelial cells express NMDA receptors
-
Sharp C.D., Fowler M., Jackson T.H.t., Houghton J., Warren A., Nanda A., Chandler I., Cappell B., Long A., Minagar A., Alexander J.S. Human neuroepithelial cells express NMDA receptors. BMC Neurosci. 2003, 4:28.
-
(2003)
BMC Neurosci.
, vol.4
, pp. 28
-
-
Sharp, C.D.1
Fowler, M.2
Jackson, T.3
Houghton, J.4
Warren, A.5
Nanda, A.6
Chandler, I.7
Cappell, B.8
Long, A.9
Minagar, A.10
Alexander, J.S.11
-
46
-
-
0345303766
-
Glutamate causes a loss in human cerebral endothelial barrier integrity through activation of NMDA receptor
-
Sharp C.D., Hines I., Houghton J., Warren A., Jackson T.H.t., Jawahar A., Nanda A., Elrod J.W., Long A., Chi A., Minagar A., Alexander J.S. Glutamate causes a loss in human cerebral endothelial barrier integrity through activation of NMDA receptor. Am. J. Physiol. Heart Circ. Physiol. 2003, 285:H2592-H2598.
-
(2003)
Am. J. Physiol. Heart Circ. Physiol.
, vol.285
-
-
Sharp, C.D.1
Hines, I.2
Houghton, J.3
Warren, A.4
Jackson, T.5
Jawahar, A.6
Nanda, A.7
Elrod, J.W.8
Long, A.9
Chi, A.10
Minagar, A.11
Alexander, J.S.12
-
47
-
-
15744362982
-
N-Methyl-d-aspartate receptor activation in human cerebral endothelium promotes intracellular oxidant stress
-
Sharp C.D., Houghton J., Elrod J.W., Warren A., Jackson T.H.t., Jawahar A., Nanda A., Minagar A., Alexander J.S. N-Methyl-d-aspartate receptor activation in human cerebral endothelium promotes intracellular oxidant stress. Am. J. Physiol. Heart Circ. Physiol. 2005, 288:H1893-H1899.
-
(2005)
Am. J. Physiol. Heart Circ. Physiol.
, vol.288
-
-
Sharp, C.D.1
Houghton, J.2
Elrod, J.W.3
Warren, A.4
Jackson, T.5
Jawahar, A.6
Nanda, A.7
Minagar, A.8
Alexander, J.S.9
-
48
-
-
0037381014
-
L-Homocysteine sulfinic acid and other acidic homocysteine derivatives are potent and selective metabotropic glutamate receptor agonists
-
Shi Q., Savage J.E., Hufeisen S.J., Rauser L., Grajkowska E., Ernsberger P., Wroblewski J.T., Nadeau J.H., Roth B.L. l-Homocysteine sulfinic acid and other acidic homocysteine derivatives are potent and selective metabotropic glutamate receptor agonists. J. Pharmacol. Exp. Ther. 2003, 305:131-142.
-
(2003)
J. Pharmacol. Exp. Ther.
, vol.305
, pp. 131-142
-
-
Shi, Q.1
Savage, J.E.2
Hufeisen, S.J.3
Rauser, L.4
Grajkowska, E.5
Ernsberger, P.6
Wroblewski, J.T.7
Nadeau, J.H.8
Roth, B.L.9
-
49
-
-
59049085356
-
Homocysteine decreases platelet NO level via protein kinase C activation
-
Signorello M.G., Segantin A., Passalacqua M., Leoncini G. Homocysteine decreases platelet NO level via protein kinase C activation. Nitric Oxide 2009, 20:104-113.
-
(2009)
Nitric Oxide
, vol.20
, pp. 104-113
-
-
Signorello, M.G.1
Segantin, A.2
Passalacqua, M.3
Leoncini, G.4
-
50
-
-
33747262660
-
Homocysteine stimulates phosphorylation of NADPH oxidase p47phox and p67phox subunits in monocytes via protein kinase Cbeta activation
-
Siow Y.L., Au-Yeung K.K., Woo C.W., O, K. Homocysteine stimulates phosphorylation of NADPH oxidase p47phox and p67phox subunits in monocytes via protein kinase Cbeta activation. Biochem. J. 2006, 398:73-82.
-
(2006)
Biochem. J.
, vol.398
, pp. 73-82
-
-
Siow, Y.L.1
Au-Yeung, K.K.2
Woo, C.W.3
O, K.4
-
51
-
-
48649101326
-
Endothelial adherens junctions control tight junctions by VE-cadherin-mediated upregulation of claudin-5
-
Taddei A., Giampietro C., Conti A., Orsenigo F., Breviario F., Pirazzoli V., Potente M., Daly C., Dimmeler S., Dejana E. Endothelial adherens junctions control tight junctions by VE-cadherin-mediated upregulation of claudin-5. Nat. Cell Biol. 2008, 10:923-934.
-
(2008)
Nat. Cell Biol.
, vol.10
, pp. 923-934
-
-
Taddei, A.1
Giampietro, C.2
Conti, A.3
Orsenigo, F.4
Breviario, F.5
Pirazzoli, V.6
Potente, M.7
Daly, C.8
Dimmeler, S.9
Dejana, E.10
-
52
-
-
0027209184
-
Regulation of NMDA receptor phosphorylation by alternative splicing of the c-terminal domain
-
Tingley W.G., Roche K.W., Thompson A.K., Huganir R.L. Regulation of NMDA receptor phosphorylation by alternative splicing of the c-terminal domain. Nature 1993, 364:70-73.
-
(1993)
Nature
, vol.364
, pp. 70-73
-
-
Tingley, W.G.1
Roche, K.W.2
Thompson, A.K.3
Huganir, R.L.4
-
53
-
-
0024342063
-
Plasma homocysteine, a risk factor for vascular disease: plasma levels in health, disease, and drug therapy
-
Ueland P.M., Refsum H. Plasma homocysteine, a risk factor for vascular disease: plasma levels in health, disease, and drug therapy. J. Lab. Clin. Med. 1989, 114:473-501.
-
(1989)
J. Lab. Clin. Med.
, vol.114
, pp. 473-501
-
-
Ueland, P.M.1
Refsum, H.2
-
54
-
-
0037164375
-
Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis
-
Wald D.S., Law M., Morris J.K. Homocysteine and cardiovascular disease: evidence on causality from a meta-analysis. BMJ 2002, 325:1202.
-
(2002)
BMJ
, vol.325
, pp. 1202
-
-
Wald, D.S.1
Law, M.2
Morris, J.K.3
-
55
-
-
0031876304
-
Production of vascular endothelial growth factor by murine macrophages: regulation by hypoxia, lactate, and the inducible nitric oxide synthase pathway
-
Xiong M., Elson G., Legarda D., Leibovich S.J. Production of vascular endothelial growth factor by murine macrophages: regulation by hypoxia, lactate, and the inducible nitric oxide synthase pathway. Am. J. Pathol. 1998, 153:587-598.
-
(1998)
Am. J. Pathol.
, vol.153
, pp. 587-598
-
-
Xiong, M.1
Elson, G.2
Legarda, D.3
Leibovich, S.J.4
-
56
-
-
70549089810
-
High plasma homocysteine levels contribute to the risk of stroke recurrence and all-cause mortality in a large prospective stroke population
-
Zhang W., Sun K., Chen J., Liao Y., Qin Q., Ma A., Wang D., Zhu Z., Wang Y., Hui R. High plasma homocysteine levels contribute to the risk of stroke recurrence and all-cause mortality in a large prospective stroke population. Clin. Sci. (Lond.) 2010, 118:187-194.
-
(2010)
Clin. Sci. (Lond.)
, vol.118
, pp. 187-194
-
-
Zhang, W.1
Sun, K.2
Chen, J.3
Liao, Y.4
Qin, Q.5
Ma, A.6
Wang, D.7
Zhu, Z.8
Wang, Y.9
Hui, R.10
-
57
-
-
0038664379
-
Role of group I metabotropic glutamate receptors and NMDA receptors in homocysteine-evoked acute neurodegeneration of cultured cerebellar granule neurones
-
Zieminska E., Stafiej A., Lazarewicz J.W. Role of group I metabotropic glutamate receptors and NMDA receptors in homocysteine-evoked acute neurodegeneration of cultured cerebellar granule neurones. Neurochem. Int. 2003, 43:481-492.
-
(2003)
Neurochem. Int.
, vol.43
, pp. 481-492
-
-
Zieminska, E.1
Stafiej, A.2
Lazarewicz, J.W.3
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