Poly(ethylene oxide) grafted with short polyethylenimine gives DNA polyplexes with superior colloidal stability, low cytotoxicity, and potent in vitro gene transfection under serum conditions

Biomacromolecules

Volumn 13, Issue 3, 2012, Pages 881-888

  Zhong, Zhiyuan ^a   Zheng, Meng ^a   Zhong, Zhihong ^b   Zhou, Lei ^a   Meng, Fenghua ^a   Peng, Rui ^a  

^a SOOCHOW UNIVERSITY   (China)

^b Lanzhou Military Command Center for Disease Control and Prevention   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CELL VIABILITY; COLLOIDAL STABILITY; CONFOCAL LASER SCANNING MICROSCOPY; GEL ELECTROPHORESIS; GENE TRANSFECTION; GRAFT DENSITY; IN-VITRO; IN-VIVO; MTT ASSAYS; NONVIRAL GENE TRANSFER; PEO MOLECULAR WEIGHT; PHYSIOLOGICAL SALT; POLYETHYLENIMINES; POLYPLEXES; POSITIVE SURFACE CHARGE; SHIELDING EFFECT; TRANSFECTION ACTIVITY; TRANSFECTION EFFICIENCY; ZETA POTENTIAL MEASUREMENTS;

BODY FLUIDS; CELLS; CONFOCAL MICROSCOPY; CYTOLOGY; CYTOTOXICITY; DNA; DYNAMIC LIGHT SCATTERING; ELECTROPHORESIS; GENES; GRAFT COPOLYMERS; GRAFTING (CHEMICAL); MOLECULAR WEIGHT; POLYETHYLENE OXIDES; ZETA POTENTIAL;

MOLECULAR BIOLOGY;

COPOLYMER; DNA; GREEN FLUORESCENT PROTEIN; MACROGOL; POLYETHYLENEIMINE;

ARTICLE; BIOCOMPATIBILITY; CELL VIABILITY; CHEMICAL COMPOSITION; COLLOID; CONFOCAL LASER MICROSCOPY; CYTOTOXICITY; GEL ELECTROPHORESIS; GENETIC TRANSFECTION; HYDROPHILICITY; IN VITRO STUDY; LIGHT SCATTERING; MOLECULAR WEIGHT; NONVIRAL GENE DELIVERY SYSTEM; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTON NUCLEAR MAGNETIC RESONANCE; SURFACE CHARGE; SYNTHESIS; ZETA POTENTIAL;

CELL SURVIVAL; CELLS, CULTURED; COLLOIDS; DNA; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; HUMANS; KIDNEY; MOLECULAR WEIGHT; PARTICLE SIZE; POLYETHYLENE GLYCOLS; POLYETHYLENEIMINE; POLYMERS; SERUM; SURFACE-ACTIVE AGENTS; TRANSFECTION;

EID: 84858136098     PISSN: 15257797     EISSN: 15264602     Source Type: Journal    
DOI: 10.1021/bm2017965     Document Type: Article

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