-
1
-
-
77950280868
-
Prospective surveillance for invasive fungal infections in hematopoietic stem cell transplant recipients, 2001–2006: overview of the Transplant-Associated Infection Surveillance Network (TRANSNET) Database
-
Kontoyiannis DP, Marr KA, Park BJ et al (2010) Prospective surveillance for invasive fungal infections in hematopoietic stem cell transplant recipients, 2001–2006: overview of the Transplant-Associated Infection Surveillance Network (TRANSNET) Database. Clin Infect Dis 50:1091–1100.
-
(2010)
Clin Infect Dis
, vol.50
, pp. 1091-1100
-
-
Kontoyiannis, DP1
Marr, KA2
Park, BJ3
-
2
-
-
67651114113
-
Invasive mould infections in the setting of hematopoietic cell transplantation: current trends and new challenges
-
Ben-Ami R, Lewis RE and Kontoyiannis DP (2009) Invasive mould infections in the setting of hematopoietic cell transplantation: current trends and new challenges. Curr Opin Infect Dis 22:376–384.
-
(2009)
Curr Opin Infect Dis
, vol.22
, pp. 376-384
-
-
Ben-Ami, R1
Lewis, RE2
Kontoyiannis, DP3
-
3
-
-
0345168856
-
Combination chemotherapy for invasive fungal infections: what laboratory and clinical studies tell us so far
-
Kontoyiannis DP and Lewis RE (2003) Combination chemotherapy for invasive fungal infections: what laboratory and clinical studies tell us so far. Drug Resist Update 6:257–269.
-
(2003)
Drug Resist Update
, vol.6
, pp. 257-269
-
-
Kontoyiannis, DP1
Lewis, RE2
-
4
-
-
0027316858
-
Antifungal susceptibility testing. Current state of technology, limitations, and standardization
-
Pfaller MA and Rinaldi MG (1993) Antifungal susceptibility testing. Current state of technology, limitations, and standardization. Infect Dis Clin North Am 2:435–444.
-
(1993)
Infect Dis Clin North Am
, vol.2
, pp. 435-444
-
-
Pfaller, MA1
Rinaldi, MG2
-
5
-
-
24144489493
-
Aspergillus susceptibility testing in patients with cancer and invasive aspergillosis: difficulties in establishing correlation between in vitro susceptibility data and the outcome of initial amphotericin B therapy
-
Lionakis MS, Lewis RE, Chamilos G and Kontoyiannis DP (2005) Aspergillus susceptibility testing in patients with cancer and invasive aspergillosis: difficulties in establishing correlation between in vitro susceptibility data and the outcome of initial amphotericin B therapy. Pharmacotherapy 25:1174–1180.
-
(2005)
Pharmacotherapy
, vol.25
, pp. 1174-1180
-
-
Lionakis, MS1
Lewis, RE2
Chamilos, G3
Kontoyiannis, DP4
-
6
-
-
0036784068
-
Itraconazole preexposure attenuates the efficacy of subsequent amphotericin B therapy in a murine model of acute invasive pulmonary aspergillosis
-
Lewis RE, Prince RA, Chi J and Kontoyiannis DP (2002) Itraconazole preexposure attenuates the efficacy of subsequent amphotericin B therapy in a murine model of acute invasive pulmonary aspergillosis. Antimicrob Agents Chemother 46:3208–3214.
-
(2002)
Antimicrob Agents Chemother
, vol.46
, pp. 3208-3214
-
-
Lewis, RE1
Prince, RA2
Chi, J3
Kontoyiannis, DP4
-
7
-
-
20144389443
-
Efficacy and safety of generic amphotericin B in experimental pulmonary aspergillosis
-
Petraitis V, Petraitiene R, Lin P et al (2005) Efficacy and safety of generic amphotericin B in experimental pulmonary aspergillosis. Antimicrob Agents Chemother 49: 1642–1645.
-
(2005)
Antimicrob Agents Chemother
, vol.49
, pp. 1642-1645
-
-
Petraitis, V1
Petraitiene, R2
Lin, P3
-
8
-
-
66149156458
-
Combination therapy of advanced invasive pulmonary aspergillosis in transiently neutropenic rats using human pharmacokinetic equivalent doses of voriconazole and anidula-fungin
-
van de Sande WW, Mathot RA, ten Kate MT et al (2009) Combination therapy of advanced invasive pulmonary aspergillosis in transiently neutropenic rats using human pharmacokinetic equivalent doses of voriconazole and anidula-fungin. Antimicrob Agents Chemother 53:2005–2013.
-
(2009)
Antimicrob Agents Chemother
, vol.53
, pp. 2005-2013
-
-
van de Sande, WW1
Mathot, RA2
ten Kate, MT3
-
9
-
-
46249098612
-
Assessment of Aspergillus fumigatus burden in pulmonary tissue of guinea pigs by quantitative PCR, galactomannan enzyme immunoassay, and quantitative culture
-
Vallor AC, Kirkpatrick WR, Najvar LK et al (2008) Assessment of Aspergillus fumigatus burden in pulmonary tissue of guinea pigs by quantitative PCR, galactomannan enzyme immunoassay, and quantitative culture. Antimicrob Agents Chemother 52:2593–2598.
-
(2008)
Antimicrob Agents Chemother
, vol.52
, pp. 2593-2598
-
-
Vallor, AC1
Kirkpatrick, WR2
Najvar, LK3
-
10
-
-
28644434509
-
Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus
-
Nierman WC, Pain A, Anderson MJ et al (2005) Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus. Nature 438:1151–1156.
-
(2005)
Nature
, vol.438
, pp. 1151-1156
-
-
Nierman, WC1
Pain, A2
Anderson, MJ3
-
11
-
-
8644220677
-
Siderophore biosynthesis but not reductive iron assimilation is essential for Aspergillus fumigatus virulence
-
Schrettl M, Bignell E, Kragl C et al (2004) Siderophore biosynthesis but not reductive iron assimilation is essential for Aspergillus fumigatus virulence. J Exp Med 200: 1213–1219.
-
(2004)
J Exp Med
, vol.200
, pp. 1213-1219
-
-
Schrettl, M1
Bignell, E2
Kragl, C3
-
12
-
-
34848872511
-
Distinct roles for intra-and extracellular sidero-phores during Aspergillus fumigatus infection
-
Schrettl M, Bignell E, Kragl C et al (2007) Distinct roles for intra-and extracellular sidero-phores during Aspergillus fumigatus infection. PLoS Pathog 3:1195–1207.
-
(2007)
PLoS Pathog
, vol.3
, pp. 1195-1207
-
-
Schrettl, M1
Bignell, E2
Kragl, C3
-
13
-
-
0031801247
-
The devel-opmentally regulated alb1 gene of Aspergillus fumigatus: its role in modulation of conidial morphology and virulence
-
Tsai HF, Chang YC, Washburn RG, Wheeler MH and Kwon-Chung KJ (1998) The devel-opmentally regulated alb1 gene of Aspergillus fumigatus: its role in modulation of conidial morphology and virulence. J Bacteriol 180: 3031–3038.
-
(1998)
J Bacteriol
, vol.180
, pp. 3031-3038
-
-
Tsai, HF1
Chang, YC2
Washburn, RG3
Wheeler, MH4
Kwon-Chung, KJ5
-
14
-
-
39349096343
-
Gliotoxin production in Aspergillus fumigatus contributes to host-specific differences in virulence
-
Spikes S, Xu R, Nguyen CK, Chamilos G et al (2008) Gliotoxin production in Aspergillus fumigatus contributes to host-specific differences in virulence. J Infect Dis 197:479–486.
-
(2008)
J Infect Dis
, vol.197
, pp. 479-486
-
-
Spikes, S1
Xu, R2
Nguyen, CK3
Chamilos, G4
-
15
-
-
0033920913
-
Signature-tagged and directed mutagenesis identify PABA synthetase as essential for Aspergillus fumigatus pathogenicity
-
Brown JS, Aufauvre-Brown A, Brown J, Jennings JM, Arst H Jr and Holden DW (2000) Signature-tagged and directed mutagenesis identify PABA synthetase as essential for Aspergillus fumigatus pathogenicity. Mol Microbiol 36:1371–1380.
-
(2000)
Mol Microbiol
, vol.36
, pp. 1371-1380
-
-
Brown, JS1
Aufauvre-Brown, A2
Brown, J3
Jennings, JM4
Arst, H5
Holden, DW6
-
16
-
-
3343006985
-
Disruption of the Aspergillus fumigatus gene encoding nucleolar protein CgrA impairs thermotolerant growth and reduces virulence
-
Bhabhra R, Miley MD, Mylonakis E et al (2004) Disruption of the Aspergillus fumigatus gene encoding nucleolar protein CgrA impairs thermotolerant growth and reduces virulence. Infect Immun 72:4731–4740.
-
(2004)
Infect Immun
, vol.72
, pp. 4731-4740
-
-
Bhabhra, R1
Miley, MD2
Mylonakis, E3
-
17
-
-
0037406694
-
Deletion of the Aspergillus fumigatus gene encoding the Ras-related protein RhbA reduces virulence in a model of Invasive pulmonary aspergillosis
-
Panepinto JC, Oliver BG, Fortwendel JR, Smith DL, Askew DS and Rhodes JC (2003) Deletion of the Aspergillus fumigatus gene encoding the Ras-related protein RhbA reduces virulence in a model of Invasive pulmonary aspergillosis. Infect Immun 71:2819–2826.
-
(2003)
Infect Immun
, vol.71
, pp. 2819-2826
-
-
Panepinto, JC1
Oliver, BG2
Fortwendel, JR3
Smith, DL4
Askew, DS5
Rhodes, JC6
-
18
-
-
2442506787
-
The Aspergillus fumigatus transcriptional activator CpcA contributes significantly to the virulence of this fungal pathogen
-
Krappmann S, Bignell EM, Reichard U, Rogers T, Haynes K and Braus GH (2004) The Aspergillus fumigatus transcriptional activator CpcA contributes significantly to the virulence of this fungal pathogen. Mol Microbiol 52:785–799.
-
(2004)
Mol Microbiol
, vol.52
, pp. 785-799
-
-
Krappmann, S1
Bignell, EM2
Reichard, U3
Rogers, T4
Haynes, K5
Braus, GH6
-
19
-
-
0030595339
-
The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults
-
Lemaitre B, Nicolas E, Michaut L, Reichhart JM and Hoffmann JA (1996) The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 86:973–983.
-
(1996)
Cell
, vol.86
, pp. 973-983
-
-
Lemaitre, B1
Nicolas, E2
Michaut, L3
Reichhart, JM4
Hoffmann, JA5
-
20
-
-
0031446642
-
Drosophila host defense: differential expression of antimicrobial peptide genes after infection by various classes of microorganisms
-
Lemaitre B, Reichhart JM and Hoffmann JA (1997) Drosophila host defense: differential expression of antimicrobial peptide genes after infection by various classes of microorganisms. Proc Natl Acad Sci USA 94:14614–14619.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 14614-14619
-
-
Lemaitre, B1
Reichhart, JM2
Hoffmann, JA3
-
21
-
-
3342963000
-
Challenge of Drosophila melanogaster with Cryptococcus neoformans and role of the innate immune response
-
Apidianakis Y, Rahme LG, Heitman J, Ausubel FM, Calderwood SB and Mylonakis E (2004) Challenge of Drosophila melanogaster with Cryptococcus neoformans and role of the innate immune response Eukaryot Cell 3:413–419.
-
(2004)
Eukaryot Cell
, vol.3
, pp. 413-419
-
-
Apidianakis, Y1
Rahme, LG2
Heitman, J3
Ausubel, FM4
Calderwood, SB5
Mylonakis, E6
-
22
-
-
34547613760
-
Exploiting amoeboid and non-ver-tebrate animal model systems to study the virulence of human pathogenic fungi
-
Mylonakis E, Casadevall A and Ausubel FM (2007) Exploiting amoeboid and non-ver-tebrate animal model systems to study the virulence of human pathogenic fungi. PLoS Pathog 3:e101.
-
(2007)
PLoS Pathog
, vol.3
, pp. e101
-
-
Mylonakis, E1
Casadevall, A2
Ausubel, FM3
-
23
-
-
2142820096
-
Immune-deficient Drosophila melanogaster: a model for the innate immune response to human fungal pathogens
-
Alarco AM, Marcil A, Chen J, Suter B, Thomas D and Whiteway M (2004) Immune-deficient Drosophila melanogaster: a model for the innate immune response to human fungal pathogens. J Immunol 172:5622–5628.
-
(2004)
J Immunol
, vol.172
, pp. 5622-5628
-
-
Alarco, AM1
Marcil, A2
Chen, J3
Suter, B4
Thomas, D5
Whiteway, M6
-
24
-
-
0037180512
-
Killing of Caenorhabditis elegans by Cryptococcus neoformans as a model of yeast pathogenesis
-
Mylonakis E, Ausubel FM, Perfect JR, Heitman J and Calderwood SB (2002) Killing of Caenorhabditis elegans by Cryptococcus neoformans as a model of yeast pathogenesis. Proc Natl Acad Sci USA 99:15675–15680.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 15675-15680
-
-
Mylonakis, E1
Ausubel, FM2
Perfect, JR3
Heitman, J4
Calderwood, SB5
-
25
-
-
21544465310
-
Galleria mellonella as a model system to study Cryptococcus neoformans pathogenesis
-
Mylonakis E, Moreno R, El Khoury JB et al (2005) Galleria mellonella as a model system to study Cryptococcus neoformans pathogenesis. Infect Immun 73:3842–3850.
-
(2005)
Infect Immun
, vol.73
, pp. 3842-3850
-
-
Mylonakis, E1
Moreno, R2
El Khoury, JB3
-
26
-
-
0035909926
-
Cryptococcus neoformans interactions with amoebae suggest an explanation for its virulence and intracellular pathogenic strategy in macrophages
-
Steenbergen JN, Shuman HA and Casadevall A (2001) Cryptococcus neoformans interactions with amoebae suggest an explanation for its virulence and intracellular pathogenic strategy in macrophages. Proc Natl Acad Sci USA 98:15245–15250.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 15245-15250
-
-
Steenbergen, JN1
Shuman, HA2
Casadevall, A3
-
27
-
-
0041823555
-
Cryptococcus neoformans virulence is enhanced after growth in the genetically malleable host Dictyostelium discoi-deum
-
Steenbergen JN, Nosanchuk JD, Maliaris SD and Casadevall A (2003) Cryptococcus neoformans virulence is enhanced after growth in the genetically malleable host Dictyostelium discoi-deum. Infect Immun 71:4862–4872.
-
(2003)
Infect Immun
, vol.71
, pp. 4862-4872
-
-
Steenbergen, JN1
Nosanchuk, JD2
Maliaris, SD3
Casadevall, A4
-
28
-
-
0035940514
-
Genome-wide analysis of the Drosophila immune response by using oli-gonucleotide microarrays
-
De Gregorio E, Spellman PT, Rubin GM and Lemaitre B (2001) Genome-wide analysis of the Drosophila immune response by using oli-gonucleotide microarrays. Proc Natl Acad Sci USA 98:12590–12599.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 12590-12599
-
-
De Gregorio, E1
Spellman, PT2
Rubin, GM3
Lemaitre, B4
-
29
-
-
2442715852
-
Drosophila: the genetics of innate immune recognition and response
-
Brennan CA and Anderson KV (2004) Drosophila: the genetics of innate immune recognition and response. Annu Rev Immunol 22:457–483.
-
(2004)
Annu Rev Immunol
, vol.22
, pp. 457-483
-
-
Brennan, CA1
Anderson, KV2
-
30
-
-
0036167107
-
Drosophila innate immunity: an evolutionary perspective
-
Hoffmann JA and Reichhart JM (2002) Drosophila innate immunity: an evolutionary perspective. Nat Immunol 3:121–126.
-
(2002)
Nat Immunol
, vol.3
, pp. 121-126
-
-
Hoffmann, JA1
Reichhart, JM2
-
31
-
-
0037013856
-
The Toll and Imd pathways are the major regulators of the immune response in Drosophila
-
De Gregorio E, Spellman PT, Tzou P, Rubin GM and Lemaitre B (2002) The Toll and Imd pathways are the major regulators of the immune response in Drosophila . EMBO J 21: 2568–2579.
-
(2002)
EMBO J
, vol.21
, pp. 2568-2579
-
-
De Gregorio, E1
Spellman, PT2
Tzou, P3
Rubin, GM4
Lemaitre, B5
-
32
-
-
15544363784
-
Toll-deficient Drosophila flies as a fast, high-throughput model for the study of antifungal drug efficacy against invasive aspergillosis and Aspergillus virulence
-
Lionakis MS, Lewis RE, May GS et al (2005) Toll-deficient Drosophila flies as a fast, high-throughput model for the study of antifungal drug efficacy against invasive aspergillosis and Aspergillus virulence. J Infect Dis 191: 1188–1195.
-
(2005)
J Infect Dis
, vol.191
, pp. 1188-1195
-
-
Lionakis, MS1
Lewis, RE2
May, GS3
-
33
-
-
76649115615
-
Interstrain variability in the virulence of Aspergillus fumigatus and Aspergillus terreus in a Toll-deficient Drosophila fly model of invasive aspergillosis
-
Ben-Ami R, Lamaris GA, Lewis RE and Kontoyiannis DP (2010) Interstrain variability in the virulence of Aspergillus fumigatus and Aspergillus terreus in a Toll-deficient Drosophila fly model of invasive aspergillosis. Med Mycol 48:310–317.
-
(2010)
Med Mycol
, vol.48
, pp. 310-317
-
-
Ben-Ami, R1
Lamaris, GA2
Lewis, RE3
Kontoyiannis, DP4
-
34
-
-
48249108357
-
Drosophila melanogaster as a model host to dissect the immunopathogenesis of zygomycosis
-
Chamilos G, Lewis RE, Hu J et al (2008) Drosophila melanogaster as a model host to dissect the immunopathogenesis of zygomycosis. Proc Natl Acad Sci USA. 105:9367–9372.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 9367-9372
-
-
Chamilos, G1
Lewis, RE2
Hu, J3
-
35
-
-
70349324685
-
Culture medium composition affects the lethality of Cunninghamella bertholletiae in a fly model of mucormycosis
-
Pongas GN, Ben-Ami R, Lewis RE, Walsh TJ and Kontoyiannis DP (2009) Culture medium composition affects the lethality of Cunninghamella bertholletiae in a fly model of mucormycosis. Antimicrob Agents Chemother 53:4569.
-
(2009)
Antimicrob Agents Chemother
, vol.53
, pp. 4569
-
-
Pongas, GN1
Ben-Ami, R2
Lewis, RE3
Walsh, TJ4
Kontoyiannis, DP5
-
36
-
-
39149088004
-
Virulence studies of Scedosporium and Fusarium species in Drosophila melanogaster
-
Lamaris GA, Chamilos G, Lewis RE and Kontoyiannis DP (2007) Virulence studies of Scedosporium and Fusarium species in Drosophila melanogaster. J Infect Dis 196: 1860–1864.
-
(2007)
J Infect Dis
, vol.196
, pp. 1860-1864
-
-
Lamaris, GA1
Chamilos, G2
Lewis, RE3
Kontoyiannis, DP4
-
37
-
-
33645360264
-
Drosophila melanogaster as a facile model for large-scale studies of virulence mechanisms and antifungal drug efficacy in Candida species
-
Chamilos G, Lionakis MS, Lewis RE et al (2006) Drosophila melanogaster as a facile model for large-scale studies of virulence mechanisms and antifungal drug efficacy in Candida species. J Infect Dis 193:1014–1022.
-
(2006)
J Infect Dis
, vol.193
, pp. 1014-1022
-
-
Chamilos, G1
Lionakis, MS2
Lewis, RE3
-
38
-
-
22844431721
-
Fruit flies as a minihost model for studying drug activity and virulence in Aspergillus
-
Suppl 1
-
Lionakis MS and Kontoyiannis DP (2005) Fruit flies as a minihost model for studying drug activity and virulence in Aspergillus. Med Mycol 43 Suppl 1:S111-114.
-
(2005)
Med Mycol
, vol.43
, pp. S111-S114
-
-
Lionakis, MS1
Kontoyiannis, DP2
-
39
-
-
77950552896
-
Exploring the concordance of Aspergillus fumigatus pathogenicity in mice and Toll-deficient flies
-
Chamilos G, Bignell EM, Schrettl M et al (2010) Exploring the concordance of Aspergillus fumigatus pathogenicity in mice and Toll-deficient flies. Med Mycol 48:506–510.
-
(2010)
Med Mycol
, vol.48
, pp. 506-510
-
-
Chamilos, G1
Bignell, EM2
Schrettl, M3
-
40
-
-
0035123039
-
Synergistic interaction of terbinafine with triazoles or amphotericin B against Aspergillus species
-
Ryder NS and Leitner I (2001) Synergistic interaction of terbinafine with triazoles or amphotericin B against Aspergillus species. Med Mycol 39:91–95.
-
(2001)
Med Mycol
, vol.39
, pp. 91-95
-
-
Ryder, NS1
Leitner, I2
-
41
-
-
0035188628
-
Quantitative PCR assay to measure Aspergillus fumigatus burden in a murine model of disseminated aspergillosis: demonstration of efficacy of caspofungin acetate
-
Bowman JC, Abruzzo GK, Anderson JW et al (2001) Quantitative PCR assay to measure Aspergillus fumigatus burden in a murine model of disseminated aspergillosis: demonstration of efficacy of caspofungin acetate. Antimicrob Agents Chemother 45:3474–3481.
-
(2001)
Antimicrob Agents Chemother
, vol.45
, pp. 3474-3481
-
-
Bowman, JC1
Abruzzo, GK2
Anderson, JW3
-
42
-
-
79251495830
-
Toll pathway in Drosophila melanogaster: A possible role to study the impact of immune senescence in poor responses against Aspergillus fumigatus
-
New Orleans, LA, USA, Abstract 31
-
Kontoyiannis DP, Lionakis MS and Halder G (2004) Toll pathway in Drosophila melanogaster: A possible role to study the impact of immune senescence in poor responses against Aspergillus fumigatus. 14th Focus on Fungal Infections, New Orleans, LA, USA, Abstract # 31.
-
(2004)
14th Focus on Fungal Infections
-
-
Kontoyiannis, DP1
Lionakis, MS2
Halder, G3
|