The death domain-containing protein Unc5CL is a novel MyD88-independent activator of the pro-inflammatory IRAK signaling cascade

Cell Death and Differentiation

Volumn 19, Issue 4, 2012, Pages 722-731

  Heinz, L X ^a   Rebsamen, M ^a   Rossi, D C ^a   Staehli, F ^a   Schroder, K ^a,b   Quadroni, M ^a   Gross, O ^a   Schneider, P ^a   Tschopp, J ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

^b UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

chemokines; death domain; JNK; mucosal immunity; NF kappaB

Indexed keywords

CXCL1 CHEMOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 4; INTERLEUKIN 8; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; MYELOID DIFFERENTIATION FACTOR 88; PROTEIN; STRESS ACTIVATED PROTEIN KINASE; UNC5C LIKE PROTEIN; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; EPITHELIUM CELL; FEMALE; GENE TARGETING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; INFLAMMATION; MALE; MOUSE; MUCOSA; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

ANIMALS; CARRIER PROTEINS; CHEMOKINES; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; INFLAMMATORY BOWEL DISEASES; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MYELOID DIFFERENTIATION FACTOR 88; NF-KAPPA B; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION;

EID: 84858114047     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2011.147     Document Type: Article

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