Peptidoglycan recognition protein 3 (PglyRP3) has an anti-inflammatory role in intestinal epithelial cells

Immunobiology

Volumn 217, Issue 4, 2012, Pages 412-419

  Zenhom, Marwa ^a   Hyder, Ayman ^a   De Vrese, Michael ^a   Heller, Knut J ^a   Roeder, Thomas ^b   Schrezenmeir, Jürgen ^a,c,d  

^a FEDERAL RESEARCH INSTITUTE OF NUTRITION AND FOOD   (Germany)

^b UNIVERSITY OF KIEL   (Germany)

^c UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^d JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

Caco 2; Inflammation; Peptidoglycan (PGN); PGlyRP3

Indexed keywords

INTERLEUKIN 12; INTERLEUKIN 8; PEPTIDOGLYCAN RECOGNITION PROTEIN; PEPTIDOGLYCAN RECOGNITION PROTEIN 3; PROTEIN P35; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ARTICLE; BACILLUS SUBTILIS; BACTERIUM IDENTIFICATION; BACTERIUM ISOLATION; CELL ACTIVATION; CELL DIFFERENTIATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; INNATE IMMUNITY; INTERMETHOD COMPARISON; INTESTINE EPITHELIUM CELL; LACTOBACILLUS RHAMNOSUS; MICROCOCCUS LUTEUS; NONHUMAN; PEPTIDOGLYCAN RECOGNITION PROTEIN 3 GENE; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR GENE; SIGNAL TRANSDUCTION; STAPHYLOCOCCUS AUREUS; WESTERN BLOTTING;

ANTI-INFLAMMATORY AGENTS; BACILLUS SUBTILIS; CACO-2 CELLS; CARRIER PROTEINS; CYTOKINES; GASTROENTERITIS; GENE EXPRESSION REGULATION; HOST-PATHOGEN INTERACTIONS; HUMANS; INFLAMMATION MEDIATORS; INTESTINAL MUCOSA; LACTOBACILLUS RHAMNOSUS; MICROCOCCUS LUTEUS; PEPTIDOGLYCAN; RNA, SMALL INTERFERING; STAPHYLOCOCCUS AUREUS; TOLL-LIKE RECEPTOR 2; TRANSGENES;

EID: 84858005470     PISSN: 01712985     EISSN: 18783279     Source Type: Journal    
DOI: 10.1016/j.imbio.2011.10.013     Document Type: Article

References (47)

1. Aderem A., Ulevitch R. Toll-like receptors in the induction of the innate immune response. Nature 2000, 406:782-787.
2. Akira S., Uematsu S., Takeuchi O. Pathogen recognition and innate immunity. Cell 2006, 124:783-791.
3. Bertin J., Nir J., Fischer M., Tayber V., Errada R., Grant R., Keilty J., Gosselin M., Robison E., Wong H. Human CARD4 protein is a novel CED-4/Apaf-1 cell death family member that activates NF-κB. J. Biol. Chem. 1999, 274:12955-12958.
4. Beutler B. TLR4 central component of the sole mammalian LPS sensor. Curr. Opin. Immunol. 2000, 12:20-26.
5. Burroughs M., Rozdzinski E., Geelen S., Tuomanen E. A structure-activity relationship for induction of meningeal inflammation by muramyl peptides. J. Clin. Invest. 1993, 92:297-302.
6. Chamaillard M., Girardin S., Viala J., Philpott J. Nods Nalps and Naip: intracellular regulators of bacterial-induced inflammation. Cell. Microbiol. 2003, 5:581-592.
7. Chaput C., Boneca I. Peptidoglycan detection by mammals and flies. Microbes Infect. 2007, 9:637-647.
8. Chen C., Liao C., Hsu M., Liao Y., Lin C., Sheu J., Huang C. Peptidoglycan-induced IL-6 production in RAW 264.7 macrophages is mediated by cyclooxygenase-2, PGE2/PGE4 receptors, Protein Kinase A, IB Kinase, and NF-κB1. J. Immun. 2005, 177:681-693.
9. Cundell R., Kanthakumar K., Taylor W., Goldman E., Flak T., Cole J., Wilson R. Effect of tracheal cytotoxin from Bordetella pertussis on human neutrophil function in vitro. Infect. Immun. 1994, 62:639-643.
10. Dalldorf G., Cromartie J., Anderle K., Clark L., Schwab H. The relation of experimental arthritis to the distribution of streptococcal cell wall fragments. Am. J. Pathol. 1980, 100:383-392.
11. Dokter H., Dijkstra J., Koopmans B., Stulp K., Keck W., Halie R., Vellenga E. G (Anh) MTetra, a natural bacterial cell wall breakdown product, induces interleukin-1 and interleukin-6 expression in human monocytes. A study of the molecular mechanisms involved in inflammatory cytokine expression. J. Biol. Chem. 1994, 269:4201-4206.
12. Dziarski R., Ulmer J., Gupta D. Interactions of CD14 with components of Gram-positive bacteria. Chem. Immunol. 2000, 74:83-107.
13. Dziarski R., Wang Q., Kirschning J., Miyake K., Gupta D. MD-2 enables Toll-like receptor-2 (TLR2)-mediated responses to LPS and enhances TLR2-mediated responses to Gram-positive and Gram-negative bacteria and their cell wall components. J. Immunol. 2001, 166:1938-1944.
14. Gelius E., Persson C., Karlsson J., Steiner H. A mammalian peptidoglycan recognition protein with N-acetylmuramoyl-L-alanine amidase activity. Biochem. Biophys. Res. Commun. 2003, 306:988-994.
15. Gold R., Miller L., Mishell I. Soluble non-cross-linked peptidoglycan polymers stimulate monocyte-macrophage inflammatory functions. Infect. Immun. 1985, 49:731-741.
16. Guan R., Roychowdhury A., Ember B., Kumar S., Boons J., Mariuzza A. Structural basis for peptidoglycan binding by peptidoglycan recognition proteins. Proc. Natl. Acad. Sci. U.S.A. 2004, 101:17168-17173.
17. Hoffmann A., Kafatos C., Janeway A., Ezekowitz A. Phylogenetic perspectives in innate immunity. Science 1999, 284:1313-1318.
18. Horng T., Barton M., Medzhitov R. TIRAP: an adapter molecule in the Toll signaling pathway. Nat. Immunol. 2001, 2:835-841.
19. Horng T., Barton M., Flavell A., Medzhitov R. The adaptor molecule TIRAP provides signaling specificity for Toll-like receptors. Nature 2002, 420:329-333.
20. Hosoi T., Hirose R., Saegusa S., Ametani A., Kiuchi K., Kaminogawa S. Cytokine responses of human intestinal epithelial-like Caco-2 cells to the nonpathogenic bacterium Bacillus subtilis (natto). Int. J. Food Microbiol. 2003, 82:255-264.
21. Hugot P., Chamaillard M., Zouali H., Lesage S., Cezard P., Belaiche J., Almer S., Tysk C., O'Morain A., Gassull M., Binder V., Finkel Y., Cortot A., Modigliani R., Laurent-Puig P., Gower-Rousseau C., Macry J., Colombel F., Sahbatou M., Thomas G. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature 2001, 411:599-603.
22. Inohara N., Nunez G. NODs: intracellular proteins involved in inflammation and apoptosis. Nat. Rev. Immunol. 2003, 3:371-382.
23. Inohara N., Kosek T., del Peso L., Hu Y., Yee C., Chen S., Carrio R., Merino J., Liu D., Ni J., Nunez G. Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-B. J. Biol. Chem. 1999, 274:14560-14567.
24. Jin Qi S., Wang S., Wang M., Li X., Kim Y., Nunez G., Gupta D., Dziarski R. PGlyRP-2 and Nod2 are both required for peptidoglycan-induced arthritis and local inflammation. Cell 2009, 5:137-150.
25. Kim S., Byun M., Oh H. Crystal structure of peptidoglycan recognition protein LB from Drosophila melanogaster. Nat. Immunol. 2003, 4:787-793.
26. Liu C., Gelius E., Liu G., Steine H., Dziarsk R. Mammalian peptidoglycan recognition protein binds peptidoglycan with high affinity, is expressed in neutrophils, and inhibits bacterial growth. J. Biol. Chem. 2000, 275:24490-24499.
27. Lu X., Wang M., Qi J., Wang H., Li X., Gupta D., Dziarski R. Peptidoglycan recognition proteins are a new class of human bactericidal proteins. J. Biol. Chem. 2005, 281:5895-5907.
28. Luker E., Collier L., Kolodziej W., Marshall R., Goldman E. Bordetella pertussis tracheal cytotoxin and other muramyl peptides: distinct structure-activity relationships for respiratory epithelial cytopathology. Proc. Natl. Acad. Sci. U.S.A. 1993, 90:2365-2369.
29. Maa P., Wang Z., Pflugfelder S., Li D. Toll-like receptors mediate induction of peptidoglycan recognition proteins in human corneal epithelial cells. Exp. Eye Res. 2010, 90:130-136.
30. Mathur P., Murray B., Crowell T., Gardner H., Allaire N., Hsu Y.M., Thill G., Carulli P. Murine peptidoglycan recognition proteins PglyrpIβ and PglyrpIβ are encoded in the epidermal differentiation complex and are expressed in epidermal and hematopoietic tissues. Genomics 2004, 83:1151-1163.
31. Matsushima K., Ohbayashi E., Takeuchi H., Hosoya S., Abiko Y., Yamazaki M. Stimulation of interleukin-6 production in human dental pulp cells by peptidoglycans from Lactobacillus casei. J. Endod. 2007, 24:252-255.
32. Medzhitov R., Janeway A. An ancient system of host defense. Curr. Opin. Immunol. 1998, 10:12-15.
33. O'Neill A., Bowie G. The family of five: TIR domain-containing adaptors in Toll-like receptor signalling. Nat. Rev. Immunol. 2007, 7:353-364.
34. Ogura Y., Bonen K., Inohara N., Nicolae L., Chen F., Ramos R., Britton H., Moran T., Karaliuskas R., Duerr H., Achkar P., Brant R., Bayless M., Kirschner S., Hanauer B., Nuñez G., Cho H. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature 2001, 411:603-606.
35. Rosenberg H. Rational design of MyD88 inhibitors-new pathways to inflammatory control. J. Leukoc. Biol. 2007, 82:811-812.
36. Royet J., Dziarski R. Peptidoglycan recognition proteins: pleiotropic sensors and effectors of antimicrobial defences. Nat. Rev. Microbiol. 2007, 5:264-277.
37. Sun J., Shi Y., Le G., Xi-Yi M. Distinct immune response induced by peptidoglycan derived from Lactobacillus sp. World J. Gastroenterol. 2005, 11:6330-6337.
38. Takeuchi O., Takeda K., Hoshino K., Adachi O., Ogawa T., Akira S. Cellular responses to bacterial cell wall components are mediated through MyD88-dependent signaling cascades. Int. Immunol. 2000, 12:113-117.
39. Travassos H., Girardin E., Philpott J., Blanot D., Nahori M.A., Werts C., Boneca G. Toll-like receptor 2-dependent bacterial sensing does not occur via peptidoglycan recognition. EMBO Rep. 2004, 5:1000-1006.
40. Ulevitch J., Tobias S. Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin. Annu. Rev. Immunol. 1995, 13:437-457.
41. Underhill D., Ozinsky A., Hajjar A., Stevens A., Wilson C., Bassetti M., Aderem A. The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens. Nature 1999, 40:811-815.
42. Varadaradjalou S., Feger F., Thieblemont N., Hamouda B., Pleau M., Dy M., Arock M. Toll-like receptor 2 (TLR2) and TLR4 differentially activate human mast cells. Eur. J. Immunol. 2003, 33:899-906.
43. Wang M., Li X., Cocklin R., Wang M., Wang M., Fukase K., Inamura S., Kusumoto S., Gupta D., Dziarski R. Human peptidoglycan recognition protein-L is an N-acetylmuramoyl-L-alanine amidase. J. Biol. Chem. 2003, 278:49044-49052.
44. Yang R., Mark M., Gray A., Huang A., Xie M., Zhang M., Goddard A., Wood W., Gurney A., Godowski P. Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signaling. Nature 1998, 395:284-288.
45. Zenhom M., Hyder A., Kraus-Stojanowic I., Auinger A., Roeder T., Schrezenmeir J. PPARγ-dependent peptidoglycan recognition protein 3 (PGlyRP3) expression regulates pro-inflammatory cytokines by microbial and dietary fatty acids. Immunobiology 2010, 216:715-724.
46. Zhang F., Kirschning C., Mancinelli R., Xu X., Jin Y., Faure E., Mantovani A., Rothe M., Muzio M., Arditi M. Bacterial lipopolysaccharide activates nuclear factor-B through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes. J. Biol. Chem. 1999, 274:7611-7614.
47. Zhang L., Li N., Caicedo R., Neu J. Alive and dead Lactobacillus rhamnosus GG decrease tumor necrosis factor-induced interleukin-8 production in Caco-2 cells. J. Nutr. 2005, 135:1752-1756.