Structural basis for a molecular allosteric control mechanism of cofactor binding to nuclear receptors

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 10, 2012, Pages

  Osz, Judit ^a   Brélivet, Yann ^a   Peluso Iltis, Carole ^a   Cura, Vincent ^a   Eiler, Sylvia ^a   Ruff, Marc ^a   Bourguet, William ^b   Rochel, Natacha ^a   Moras, Dino ^a  

^a UNIVERSITÉ DE STRASBOURG   (France)

^b CNRS   (France)

Author keywords

Allostery; Structure

Indexed keywords

CELL NUCLEUS RECEPTOR; ESTROGEN RECEPTOR ALPHA; HOMODIMER; RETINOIC ACID RECEPTOR ALPHA; RETINOIC ACID RECEPTOR BETA; STEROID RECEPTOR COACTIVATOR 1;

ALLOSTERISM; ARTICLE; BINDING KINETICS; BINDING SITE; CRYSTAL STRUCTURE; LIGAND BINDING; MOLECULAR DYNAMICS; MOLECULAR MODEL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN STRUCTURE; RECEPTOR BINDING; REGULATORY MECHANISM;

ALLOSTERIC SITE; BIOPHYSICS; CELL NUCLEUS; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; HUMANS; KINETICS; LIGANDS; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MOLECULAR CONFORMATION; NUCLEAR RECEPTOR COACTIVATOR 1; PEPTIDES; PROTEIN BINDING; RECEPTORS, CALCITRIOL; RECEPTORS, RETINOIC ACID;

EID: 84857981327     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1118192109     Document Type: Article

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