Variable RXR requirements for thyroid hormone responsiveness of endogenous genes

Molecular and Cellular Endocrinology

Volumn 264, Issue 1-2, 2007, Pages 149-156

  Diallo, Ericka M ^a   Wilhelm Jr , Kenneth G ^a   Thompson, Deborah L ^a   Koenig, Ronald J ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Heterodimer; Homodimer; Retinoid X receptor; T3; Thyroid hormone receptor

Indexed keywords

COMPLEMENTARY DNA; HETERODIMER; HOMODIMER; LIOTHYRONINE; REGULATOR PROTEIN; RETINOID X RECEPTOR; SMALL INTERFERING RNA; THYROID HORMONE; THYROID HORMONE RECEPTOR; THYROID HORMONE RECEPTOR BETA;

ANIMAL CELL; ARTICLE; CELL STRAIN; COMPLEX FORMATION; CONTROLLED STUDY; DNA MICROARRAY; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; GENE INDUCTION; GENETIC ANALYSIS; HORMONE RESPONSIVE ELEMENT; KNOCKOUT GENE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RECEPTOR GENE; REGULATORY MECHANISM; RNA INTERFERENCE; RXR GENE;

ANIMALS; GENE EXPRESSION REGULATION; MICE; NEURONS; RECEPTORS, THYROID HORMONE; RETINOID X RECEPTORS; SIGNAL TRANSDUCTION; TRIIODOTHYRONINE;

EID: 33846240477     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mce.2006.11.004     Document Type: Article

References (18)

1. Carroll J.S., Liu X.S., Brodsky A.S., Li W., Meyer C.A., Szary A.J., Eeckhoute J., Shao W., Hestermann E.V., Geistlinger T.R., Fox E.A., Silver P.A., and Brown M. Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1. Cell 122 (2005) 33-43
2. Denver R.J., Ouellet L., Furling D., Kobayashi A., Fujii-Kuriyama Y., and Puymirat J. Basic transcription element-binding protein (BTEB) is a thyroid hormone-regulated gene in the developing central nervous system-evidence for a role in neurite outgrowth. J. Biol. Chem. 274 (1999) 23128-23134
3. Diallo E.M., Thompson D.L., and Koenig R.J. A method for efficient production of recombinant thyroid hormone receptors reveals that receptor homodimer-DNA binding is enhanced by the coactivator TIF2. Protein Expr. Purif. 40 (2005) 292-298
4. Izumo S., and Mahdavi V. Thyroid hormone receptor alpha isoforms generated by alternative splicing differentially activate myosin HC gene transcription. Nature 334 (1988) 539-542
5. Katz R.W., and Koenig R.J. Non-biased identification of DNA sequences which bind thyroid hormone receptor α1 with high affinity. J. Biol. Chem. 268 (1993) 19392-19397
6. Kersten S., Kelleher D., Chambon P., Gronemeyer H., and Noy N. Retinoid X receptor alpha forms tetramers in solution. Proc. Natl. Acad. Sci. U.S.A. 92 (1995) 8645-8649
7. Kliewer S.A., Umesono K., Mangelsdorf D.J., and Evans R.M. Retinoid X receptor interacts with nuclear receptors in retinoic acid, thyroid hormone and Vitamin D3 signalling. Nature 355 (1992) 446-449
8. Kurokawa R., Yu V.C., Naar A., Kyakumoto S., Han Z., Silverman S., Rosenfeld M.G., and Glass C.K. Differential orientations of the DNA-binding domain and carboxy-terminal dimerization interface regulate binding site selection by nuclear receptor heterodimers. Genes Dev. 7 (1993) 1423-1435
9. Lebel J.M., Dussault J.H., and Puymirat J. Overexpression of the beta 1 thyroid receptor induces differentiation in neuro-2a cells. Proc. Natl. Acad. Sci. U.S.A. 91 (1994) 2644-2648
10. Leid M., Kastner P., Lyons R., Nakshatri H., Saunders M., Zacharewski T., Chen J.Y., Staub A., Garnier J.M., Mader S., and Chambon P. Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently. Cell 68 (1992) 377-395
11. Murray M.B., and Towle H.C. Identification of nuclear factors that enhance binding of the thyroid hormone receptor to a thyroid hormone response element. Mol. Endocrinol. 3 (1989) 1434-1442
12. Nordeen S.K. Luciferase reporter gene vectors for analysis of promoters and enhancers. BioTechniques 6 (1988) 454-458
13. Olson D.P., and Koenig R.J. 5′ Flanking sequences in thyroid hormone response element half sites determine the requirement of RXR for receptor mediated gene expression. J. Biol. Chem. 272 (1997) 9907-9914
14. Subauste J.S., Katz R.W., and Koenig R.J. DNA binding specificity and function of retinoid X receptor α. J. Biol. Chem. 269 (1994) 30232-30237
15. Williams G.R., Harney J.W., Moore D.D., Larsen P.R., and Brent G.A. Differential capacity of wild type promoter elements for binding and trans-activation by retinoic acid and thyroid hormone receptors. Mol. Endocrinol. 6 (1992) 1527-1537
16. Yen P.M., Darling D.S., Carter R.L., Forgione M., Umeda P.K., and Chin W.W. Triiodothyronine (T3) decreases binding to DNA by T3-receptor homodimers but not receptor-auxiliary protein heterodimers. J. Biol. Chem. 267 (1992) 3565-3568
17. Yu V.C., Delsert C., Andersen B., Holloway J.M., Devary O.V., Naar A.M., Kim S.Y., Boutin J.M., Glass C.K., and Rosenfeld M.G. RXRß-A coregulator that enhances binding of retinoic acid, thyroid hormone, and Vitamin D receptors to their cognate response elements. Cell 67 (1991) 1251-1266
18. Zhang X.-K., Lehmann J., Hoffmann B., Dawson M.I., Cameron J., Graupner G., Hermann T., Tran P., and Pfahl M. Homodimer formation of retinoid X receptor induced by 9-cis retinoic acid. Nature 358 (1992) 587-591