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Volumn 1817, Issue 4, 2012, Pages 526-536

Proton-pumping mechanism of cytochrome c oxidase: A kinetic master-equation approach

Author keywords

Cytochrome c oxidase; Energy transduction; Kinetic master equation; Molecular machine; Proton pumping; Respiratory chain

Indexed keywords

CYTOCHROME C OXIDASE; GLUTAMIC ACID; OXYGEN; PROTON PUMP; WATER;

EID: 84857913911     PISSN: 00052728     EISSN: 18792650     Source Type: Journal    
DOI: 10.1016/j.bbabio.2011.09.004     Document Type: Review
Times cited : (43)

References (80)
  • 1
    • 0017358508 scopus 로고
    • Proton pump coupled to cytochrome-c oxidase in mitochondria
    • M.K.F. Wikström Proton pump coupled to cytochrome-c oxidase in mitochondria Nature 266 1977 271 273
    • (1977) Nature , vol.266 , pp. 271-273
    • Wikström, M.K.F.1
  • 2
    • 0026530174 scopus 로고
    • Oxygen activation and the conservation of energy in cell respiration
    • G.T. Babcock, and M. Wikström Oxygen activation and the conservation of energy in cell respiration Nature 356 1992 301 309
    • (1992) Nature , vol.356 , pp. 301-309
    • Babcock, G.T.1    Wikström, M.2
  • 3
  • 4
    • 0034640504 scopus 로고    scopus 로고
    • Proton pumping by cytochrome oxidase: Progress, problems and postulates
    • D. Zaslavsky, and R.B. Gennis Proton pumping by cytochrome oxidase: progress, problems and postulates Biochim. Biophys. Acta, Bioenerg. 1458 2000 164 179
    • (2000) Biochim. Biophys. Acta, Bioenerg. , vol.1458 , pp. 164-179
    • Zaslavsky, D.1    Gennis, R.B.2
  • 6
    • 1942472486 scopus 로고    scopus 로고
    • Cytochrome c oxidase: 25 years of the elusive proton pump
    • M. Wikström Cytochrome c oxidase: 25 years of the elusive proton pump Biochim. Biophys. Acta, Bioenerg. 1655 2004 241 247
    • (2004) Biochim. Biophys. Acta, Bioenerg. , vol.1655 , pp. 241-247
    • Wikström, M.1
  • 7
    • 29544449035 scopus 로고    scopus 로고
    • Biogenesis of cytochrome c oxidase
    • E. Khalimonchuk, and G. Rödel Biogenesis of cytochrome c oxidase Mitochondrion 5 2005 363 388
    • (2005) Mitochondrion , vol.5 , pp. 363-388
    • Khalimonchuk, E.1    Rödel, G.2
  • 9
    • 34848850437 scopus 로고    scopus 로고
    • Mechanism and energetics of proton translocation by the respiratory heme-copper oxidases
    • M. Wikström, and M.I. Verkhovsky Mechanism and energetics of proton translocation by the respiratory heme-copper oxidases Biochim. Biophys. Acta, Bioenerg. 1767 2007 1200 1214
    • (2007) Biochim. Biophys. Acta, Bioenerg. , vol.1767 , pp. 1200-1214
    • Wikström, M.1    Verkhovsky, M.I.2
  • 10
    • 57049180108 scopus 로고    scopus 로고
    • Cytochrome c oxidase: Exciting progress and remaining mysteries
    • P. Brzezinski, and R.B. Gennis Cytochrome c oxidase: exciting progress and remaining mysteries J. Bioenerg. Biomembr. 40 2008 521 531
    • (2008) J. Bioenerg. Biomembr. , vol.40 , pp. 521-531
    • Brzezinski, P.1    Gennis, R.B.2
  • 12
    • 0028890031 scopus 로고
    • Structure at 2.8-Angstrom resolution of cytochrome-c-oxidase from Paracoccus denitrificans
    • S. Iwata, C. Ostermeier, B. Ludwig, and H. Michel Structure at 2.8-Angstrom resolution of cytochrome-c-oxidase from Paracoccus denitrificans Nature 376 1995 660 669
    • (1995) Nature , vol.376 , pp. 660-669
    • Iwata, S.1    Ostermeier, C.2    Ludwig, B.3    Michel, H.4
  • 14
    • 0032573052 scopus 로고    scopus 로고
    • How does cytochrome oxidase pump protons?
    • R.B. Gennis How does cytochrome oxidase pump protons? Proc. Natl. Acad. Sci. U. S. A. 95 1998 12747 12749
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 12747-12749
    • Gennis, R.B.1
  • 15
    • 0017883558 scopus 로고
    • Involvement of intra-mitochondrial protons in redox reactions of cytochrome-a
    • V.Y. Artzatbanov, A.A. Konstantinov, and V.P. Skulachev Involvement of intra-mitochondrial protons in redox reactions of cytochrome-a FEBS Lett. 87 1978 180 185
    • (1978) FEBS Lett. , vol.87 , pp. 180-185
    • Artzatbanov, V.Y.1    Konstantinov, A.A.2    Skulachev, V.P.3
  • 16
    • 0032515180 scopus 로고    scopus 로고
    • A cooperative model for protonmotive heme-copper oxidases. the role of heme a in the proton pump of cytochrome c oxidase
    • S. Papa, N. Capitanio, and G. Villani A cooperative model for protonmotive heme-copper oxidases. The role of heme a in the proton pump of cytochrome c oxidase FEBS Lett. 439 1998 1 8
    • (1998) FEBS Lett. , vol.439 , pp. 1-8
    • Papa, S.1    Capitanio, N.2    Villani, G.3
  • 17
    • 0033576277 scopus 로고    scopus 로고
    • Cytochrome c oxidase: Catalytic cycle and mechanisms of proton pumping-a discussion
    • H. Michel Cytochrome c oxidase: catalytic cycle and mechanisms of proton pumping-a discussion Biochemistry 38 1999 15129 15140
    • (1999) Biochemistry , vol.38 , pp. 15129-15140
    • Michel, H.1
  • 18
    • 0142091718 scopus 로고    scopus 로고
    • Theoretical study of the energetics of proton pumping and oxygen reduction in cytochrome oxidase
    • P.E.M. Siegbahn, M.R.A. Blomberg, and M.L. Blomberg Theoretical study of the energetics of proton pumping and oxygen reduction in cytochrome oxidase J. Phys. Chem. B 107 2003 10946 10955
    • (2003) J. Phys. Chem. B , vol.107 , pp. 10946-10955
    • Siegbahn, P.E.M.1    Blomberg, M.R.A.2    Blomberg, M.L.3
  • 19
    • 1242347357 scopus 로고    scopus 로고
    • Electron transfer reactions coupled to proton translocation. Cytochrome oxidase, proton pumps, and biological energy transduction
    • A.A. Stuchebrukhov Electron transfer reactions coupled to proton translocation. Cytochrome oxidase, proton pumps, and biological energy transduction J. Theory Comput. Chem. 2 2003 91 118
    • (2003) J. Theory Comput. Chem. , vol.2 , pp. 91-118
    • Stuchebrukhov, A.A.1
  • 20
    • 33750807024 scopus 로고    scopus 로고
    • Identification of conserved lipid/detergent-binding sites in a high-resolution structure of the membrane protein cytochrome c oxidase
    • L. Qin, C. Hiser, A. Mulichak, R.M. Garavito, and S. Ferguson-Miller Identification of conserved lipid/detergent-binding sites in a high-resolution structure of the membrane protein cytochrome c oxidase Proc. Natl. Acad. Sci. U. S. A. 103 2006 16117 16122
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 16117-16122
    • Qin, L.1    Hiser, C.2    Mulichak, A.3    Garavito, R.M.4    Ferguson-Miller, S.5
  • 22
    • 24644471025 scopus 로고    scopus 로고
    • A mechanistic principle for proton pumping by cytochrome c oxidase
    • K. Faxén, G. Gilderson, P. Ädelroth, and P. Brzezinski A mechanistic principle for proton pumping by cytochrome c oxidase Nature 437 2005 286 289
    • (2005) Nature , vol.437 , pp. 286-289
    • Faxén, K.1    Gilderson, G.2    Ädelroth, P.3    Brzezinski, P.4
  • 23
    • 33645732495 scopus 로고    scopus 로고
    • Proton-coupled electron transfer drives the proton pump of cytochrome c oxidase
    • I. Belevich, M.I. Verkhovsky, and M. Wikström Proton-coupled electron transfer drives the proton pump of cytochrome c oxidase Nature 440 2006 829 832
    • (2006) Nature , vol.440 , pp. 829-832
    • Belevich, I.1    Verkhovsky, M.I.2    Wikström, M.3
  • 24
    • 33646268674 scopus 로고    scopus 로고
    • Monte Carlo simulations of proton pumps: On the working principles of the biological valve that controls proton pumping in cytochrome c oxidase
    • M.H.M. Olsson, and A. Warshel Monte Carlo simulations of proton pumps: on the working principles of the biological valve that controls proton pumping in cytochrome c oxidase Proc. Natl. Acad. Sci. U. S. A. 103 2006 6500 6505
    • (2006) Proc. Natl. Acad. Sci. U. S. A. , vol.103 , pp. 6500-6505
    • Olsson, M.H.M.1    Warshel, A.2
  • 26
    • 0032311173 scopus 로고    scopus 로고
    • Structure and dynamics of a proton shuttle in cytochrome c oxidase
    • R. Pomès, G. Hummer, and M. Wikström Structure and dynamics of a proton shuttle in cytochrome c oxidase Biochim. Biophys. Acta 1365 1998 255 260
    • (1998) Biochim. Biophys. Acta , vol.1365 , pp. 255-260
    • Pomès, R.1    Hummer, G.2    Wikström, M.3
  • 27
    • 63449091255 scopus 로고    scopus 로고
    • Functional hydration and conformational gating of proton uptake in cytochrome c oxidase
    • R.M. Henry, C.-H. Yu, T. Rodinger, and R. Pomès Functional hydration and conformational gating of proton uptake in cytochrome c oxidase J. Mol. Biol. 387 2009 1165 1185
    • (2009) J. Mol. Biol. , vol.387 , pp. 1165-1185
    • Henry, R.M.1    Yu, C.-H.2    Rodinger, T.3    Pomès, R.4
  • 28
    • 36949083936 scopus 로고
    • Coupling of phosphorylation to electron and hydrogen transfer by a chemi-osmotic type of mechanism
    • P. Mitchell Coupling of phosphorylation to electron and hydrogen transfer by a chemi-osmotic type of mechanism Nature 191 1961 144 148
    • (1961) Nature , vol.191 , pp. 144-148
    • Mitchell, P.1
  • 29
    • 2442616154 scopus 로고    scopus 로고
    • Proton pumping mechanism and catalytic cycle of cytochrome c oxidase: Coulomb pump model with kinetic gating
    • D.M. Popović, and A.A. Stuchebrukhov Proton pumping mechanism and catalytic cycle of cytochrome c oxidase: Coulomb pump model with kinetic gating FEBS Lett. 566 2004 126 130
    • (2004) FEBS Lett. , vol.566 , pp. 126-130
    • Popović, D.M.1    Stuchebrukhov, A.A.2
  • 31
    • 34547118553 scopus 로고    scopus 로고
    • Motor proteins at work for nanotechnology
    • M.G.L. van den Heuvel, and C. Dekker Motor proteins at work for nanotechnology Science 317 2007 333 336
    • (2007) Science , vol.317 , pp. 333-336
    • Van Den Heuvel, M.G.L.1    Dekker, C.2
  • 35
    • 0000013996 scopus 로고
    • Network theory of microscopic and macroscopic behavior of master equation systems
    • J. Schnakenberg Network theory of microscopic and macroscopic behavior of master equation systems Rev. Mod. Phys. 48 1976 571 585
    • (1976) Rev. Mod. Phys. , vol.48 , pp. 571-585
    • Schnakenberg, J.1
  • 36
    • 0037187085 scopus 로고    scopus 로고
    • Equations for stochastic macromolecular mechanics of single proteins: Equilibrium fluctuations, transient kinetics, and nonequilibrium steady-state
    • H. Qian Equations for stochastic macromolecular mechanics of single proteins: equilibrium fluctuations, transient kinetics, and nonequilibrium steady-state J. Phys. Chem. B 106 2002 2065 2073
    • (2002) J. Phys. Chem. B , vol.106 , pp. 2065-2073
    • Qian, H.1
  • 37
    • 33748096830 scopus 로고    scopus 로고
    • Open-system nonequilibrium steady state: Statistical thermodynamics, fluctuations, and chemical oscillations
    • H. Qian Open-system nonequilibrium steady state: statistical thermodynamics, fluctuations, and chemical oscillations J. Phys. Chem. B 110 2006 15063 15074
    • (2006) J. Phys. Chem. B , vol.110 , pp. 15063-15074
    • Qian, H.1
  • 38
    • 11744379062 scopus 로고
    • Fluctuation driven ratchets - Molecular motors
    • R.D. Astumian, and M. Bier Fluctuation driven ratchets - molecular motors Phys. Rev. Lett. 72 1994 1766 1769
    • (1994) Phys. Rev. Lett. , vol.72 , pp. 1766-1769
    • Astumian, R.D.1    Bier, M.2
  • 39
    • 0031003997 scopus 로고    scopus 로고
    • Thermodynamics and kinetics of a Brownian motor
    • R.D. Astumian Thermodynamics and kinetics of a Brownian motor Science 276 1997 917 922
    • (1997) Science , vol.276 , pp. 917-922
    • Astumian, R.D.1
  • 42
    • 69549101850 scopus 로고    scopus 로고
    • Kinetic gating of the proton pump in cytochrome c oxidase
    • Y.C. Kim, M. Wikström, and G. Hummer Kinetic gating of the proton pump in cytochrome c oxidase Proc. Natl. Acad. Sci. U. S. A. 106 2009 13707 13712
    • (2009) Proc. Natl. Acad. Sci. U. S. A. , vol.106 , pp. 13707-13712
    • Kim, Y.C.1    Wikström, M.2    Hummer, G.3
  • 43
    • 73649094464 scopus 로고    scopus 로고
    • Biological proton pumping in an oscillating electric field
    • Y.C. Kim, L.A. Furchtgott, and G. Hummer Biological proton pumping in an oscillating electric field Phys. Rev. Lett. 103 2009 4
    • (2009) Phys. Rev. Lett. , vol.103 , pp. 4
    • Kim, Y.C.1    Furchtgott, L.A.2    Hummer, G.3
  • 45
    • 0028043535 scopus 로고
    • Signal-transduction and regulation in smooth-muscle
    • A.P. Somlyo, and A.V. Somlyo Signal-transduction and regulation in smooth-muscle Nature 372 1994 231 236
    • (1994) Nature , vol.372 , pp. 231-236
    • Somlyo, A.P.1    Somlyo, A.V.2
  • 46
    • 0032489015 scopus 로고    scopus 로고
    • The cell as a collection of protein machines: Preparing the next generation of molecular biologists
    • B. Alberts The cell as a collection of protein machines: preparing the next generation of molecular biologists Cell 92 1998 291 294
    • (1998) Cell , vol.92 , pp. 291-294
    • Alberts, B.1
  • 47
    • 0026501223 scopus 로고
    • Unscrambling the puzzle of biological machines - The importance of the details
    • B. Alberts, and R. Miakelye Unscrambling the puzzle of biological machines - the importance of the details Cell 68 1992 415 420
    • (1992) Cell , vol.68 , pp. 415-420
    • Alberts, B.1    Miakelye, R.2
  • 49
    • 0030773824 scopus 로고    scopus 로고
    • Molecular motors: Structural adaptations to cellular functions
    • J. Howard Molecular motors: structural adaptations to cellular functions Nature 389 1997 561 567
    • (1997) Nature , vol.389 , pp. 561-567
    • Howard, J.1
  • 51
    • 0037026489 scopus 로고    scopus 로고
    • The voltage-gated potassium channels and their relatives
    • G. Yellen The voltage-gated potassium channels and their relatives Nature 419 2002 35 42
    • (2002) Nature , vol.419 , pp. 35-42
    • Yellen, G.1
  • 52
    • 28544453561 scopus 로고    scopus 로고
    • Principles of selective ion transport in channels and pumps
    • E. Gouaux, and R. MacKinnon Principles of selective ion transport in channels and pumps Science 310 2005 1461 1465
    • (2005) Science , vol.310 , pp. 1461-1465
    • Gouaux, E.1    MacKinnon, R.2
  • 54
    • 0034934257 scopus 로고    scopus 로고
    • Simple mechanochemistry describes the dynamics of kinesin molecules
    • M.E. Fisher, and A.B. Kolomeisky Simple mechanochemistry describes the dynamics of kinesin molecules Proc. Natl. Acad. Sci. U. S. A. 98 2001 7748 7753
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , pp. 7748-7753
    • Fisher, M.E.1    Kolomeisky, A.B.2
  • 55
    • 28044442273 scopus 로고    scopus 로고
    • Kinesin crouches to sprint but resists pushing
    • M.E. Fisher, and Y.C. Kim Kinesin crouches to sprint but resists pushing Proc. Natl. Acad. Sci. U. S. A. 102 2005 16209 16214
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 16209-16214
    • Fisher, M.E.1    Kim, Y.C.2
  • 56
    • 27744451983 scopus 로고    scopus 로고
    • Vectorial loading of processive motor proteins: Implementing a landscape picture
    • Y.C. Kim, and M.E. Fisher Vectorial loading of processive motor proteins: implementing a landscape picture J. Phys. Condens. Matter 17 2005 S3821 S3838
    • (2005) J. Phys. Condens. Matter , vol.17
    • Kim, Y.C.1    Fisher, M.E.2
  • 57
    • 0034711407 scopus 로고    scopus 로고
    • Oxygen activation and reduction in respiration: Involvement of redox-active tyrosine 244
    • D.A. Proshlyakov, M.A. Pressler, C. DeMaso, J.F. Leykam, D.L. DeWitt, and G.T. Babcock Oxygen activation and reduction in respiration: involvement of redox-active tyrosine 244 Science 290 2000 1588 1591
    • (2000) Science , vol.290 , pp. 1588-1591
    • Proshlyakov, D.A.1    Pressler, M.A.2    Demaso, C.3    Leykam, J.F.4    Dewitt, D.L.5    Babcock, G.T.6
  • 58
    • 58049192387 scopus 로고    scopus 로고
    • The protonation state of the cross-linked tyrosine during the catalytic cycle of cytochrome c oxidase
    • E.A. Gorbikova, M. Wikström, and M.I. Verkhovsky The protonation state of the cross-linked tyrosine during the catalytic cycle of cytochrome c oxidase J. Biol. Chem. 283 2008 34907 34912
    • (2008) J. Biol. Chem. , vol.283 , pp. 34907-34912
    • Gorbikova, E.A.1    Wikström, M.2    Verkhovsky, M.I.3
  • 59
  • 60
    • 0029739061 scopus 로고    scopus 로고
    • Electrostatics of a simple membrane model using green's functions formalism
    • E. von Kitzing, and D.M. Soumpasis Electrostatics of a simple membrane model using green's functions formalism Biophys. J. 71 1996 795 810
    • (1996) Biophys. J. , vol.71 , pp. 795-810
    • Von Kitzing, E.1    Soumpasis, D.M.2
  • 61
    • 0028023207 scopus 로고
    • PH-induced structural-changes in bacteriorhodopsin studied by Fourier-transform infrared-spectroscopy
    • S. Szaraz, D. Oesterhelt, and P. Ormos pH-induced structural-changes in bacteriorhodopsin studied by Fourier-transform infrared-spectroscopy Biophys. J. 67 1994 1706 1712
    • (1994) Biophys. J. , vol.67 , pp. 1706-1712
    • Szaraz, S.1    Oesterhelt, D.2    Ormos, P.3
  • 62
    • 0037452497 scopus 로고    scopus 로고
    • Intramolecular proton-transfer reactions in a membrane-bound proton pump: The effect of pH on the peroxy to ferryl transition in cytochrome c oxidase
    • A. Namslauer, A. Aagaard, A. Katsonouri, and P. Brzezinski Intramolecular proton-transfer reactions in a membrane-bound proton pump: the effect of pH on the peroxy to ferryl transition in cytochrome c oxidase Biochemistry 42 2003 1488 1498
    • (2003) Biochemistry , vol.42 , pp. 1488-1498
    • Namslauer, A.1    Aagaard, A.2    Katsonouri, A.3    Brzezinski, P.4
  • 63
    • 0027305757 scopus 로고
    • Intracomplex electron-transfer between ruthenium-cytochrome-c derivatives and cytochrome-c-oxidase
    • L.P. Pan, S. Hibdon, R.Q. Liu, B. Durham, and F. Millett Intracomplex electron-transfer between ruthenium-cytochrome-c derivatives and cytochrome-c-oxidase Biochemistry 32 1993 8492 8498
    • (1993) Biochemistry , vol.32 , pp. 8492-8498
    • Pan, L.P.1    Hibdon, S.2    Liu, R.Q.3    Durham, B.4    Millett, F.5
  • 64
    • 0028819233 scopus 로고
    • Design of a ruthenium cytochrome-c derivative to measure electron-transfer to the initial acceptor in cytochrome-c-oxidase
    • L.M. Geren, J.R. Beasley, B.R. Fine, A.J. Saunders, S. Hibdon, G.J. Pielak, B. Durham, and F. Millett Design of a ruthenium cytochrome-c derivative to measure electron-transfer to the initial acceptor in cytochrome-c-oxidase J. Biol. Chem. 270 1995 2466 2472
    • (1995) J. Biol. Chem. , vol.270 , pp. 2466-2472
    • Geren, L.M.1    Beasley, J.R.2    Fine, B.R.3    Saunders, A.J.4    Hibdon, S.5    Pielak, G.J.6    Durham, B.7    Millett, F.8
  • 65
    • 34548170174 scopus 로고    scopus 로고
    • Energy diagrams and mechanism for proton pumping in cytochrome c oxidase
    • P.E.M. Siegbahn, and M.R.A. Blomberg Energy diagrams and mechanism for proton pumping in cytochrome c oxidase Biochim. Biophys. Acta, Bioenerg. 1767 2007 1143 1156
    • (2007) Biochim. Biophys. Acta, Bioenerg. , vol.1767 , pp. 1143-1156
    • Siegbahn, P.E.M.1    Blomberg, M.R.A.2
  • 66
    • 58149147161 scopus 로고    scopus 로고
    • Proton pumping mechanism in cytochrome c oxidase
    • P.E.M. Siegbahn, and M.R.A. Blomberg Proton pumping mechanism in cytochrome c oxidase J. Phys. Chem. A 112 2008 12772 12780
    • (2008) J. Phys. Chem. A , vol.112 , pp. 12772-12780
    • Siegbahn, P.E.M.1    Blomberg, M.R.A.2
  • 68
    • 0031973948 scopus 로고    scopus 로고
    • Oxygen and proton pathways in cytochrome c oxidase
    • I. Hofacker, and K. Schulten Oxygen and proton pathways in cytochrome c oxidase Proteins 30 1998 100 107
    • (1998) Proteins , vol.30 , pp. 100-107
    • Hofacker, I.1    Schulten, K.2
  • 69
    • 17444439064 scopus 로고    scopus 로고
    • Proton transport through water-filled carbon nanotubes
    • C. Dellago, M.M. Naor, and G. Hummer Proton transport through water-filled carbon nanotubes Phys. Rev. Lett. 90 2003 4
    • (2003) Phys. Rev. Lett. , vol.90 , pp. 4
    • Dellago, C.1    Naor, M.M.2    Hummer, G.3
  • 71
    • 0034643820 scopus 로고    scopus 로고
    • Tracing the D-pathway in reconstituted site-directed mutants of cytochrome c oxidase from Paracoccus denitrificans
    • U. Pfitzner, K. Hoffmeier, A. Harrenga, A. Kannt, H. Michel, E. Bamberg, O.M.H. Richter, and B. Ludwig Tracing the D-pathway in reconstituted site-directed mutants of cytochrome c oxidase from Paracoccus denitrificans Biochemistry 39 2000 6756 6762
    • (2000) Biochemistry , vol.39 , pp. 6756-6762
    • Pfitzner, U.1    Hoffmeier, K.2    Harrenga, A.3    Kannt, A.4    Michel, H.5    Bamberg, E.6    Richter, O.M.H.7    Ludwig, B.8
  • 72
    • 0346734127 scopus 로고    scopus 로고
    • Redox-coupled proton translocation in biological systems: Proton shuttling in cytochrome c oxidase
    • A. Namslauer, A.S. Pawatet, R. Gennis, and P. Brzezinski Redox-coupled proton translocation in biological systems: proton shuttling in cytochrome c oxidase Proc. Natl. Acad. Sci. U. S. A. 100 2003 15543 15547
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 15543-15547
    • Namslauer, A.1    Pawatet, A.S.2    Gennis, R.3    Brzezinski, P.4
  • 73
    • 0031880698 scopus 로고    scopus 로고
    • The coupling of electron transfer and proton translocation: Electrostatic calculations on Paracoccus denitrificans cytochrome c oxidase
    • A. Kannt, C.R.D. Lancaster, and H. Michel The coupling of electron transfer and proton translocation: electrostatic calculations on Paracoccus denitrificans cytochrome c oxidase Biophys. J. 74 1998 708 721
    • (1998) Biophys. J. , vol.74 , pp. 708-721
    • Kannt, A.1    Lancaster, C.R.D.2    Michel, H.3
  • 74
    • 1942423697 scopus 로고    scopus 로고
    • Dynamic water networks in cytochrome c oxidase from Paracoccus denitrificans investigated by molecular dynamics simulations
    • E. Olkhova, M.C. Hutter, M.A. Lill, V. Helms, and H. Michel Dynamic water networks in cytochrome c oxidase from Paracoccus denitrificans investigated by molecular dynamics simulations Biophys. J. 86 2004 1873 1889
    • (2004) Biophys. J. , vol.86 , pp. 1873-1889
    • Olkhova, E.1    Hutter, M.C.2    Lill, M.A.3    Helms, V.4    Michel, H.5
  • 75
    • 23244450116 scopus 로고    scopus 로고
    • Water chain formation and possible proton pumping routes in Rhodobacter sphaeroides cytochrome c oxidase: A molecular dynamics comparison of the wild type and R481K mutant
    • S.A. Seibold, D.A. Mills, S. Ferguson-Miller, and R.I. Cukier Water chain formation and possible proton pumping routes in Rhodobacter sphaeroides cytochrome c oxidase: a molecular dynamics comparison of the wild type and R481K mutant Biochemistry 44 2005 10475 10485
    • (2005) Biochemistry , vol.44 , pp. 10475-10485
    • Seibold, S.A.1    Mills, D.A.2    Ferguson-Miller, S.3    Cukier, R.I.4
  • 76
    • 38749152834 scopus 로고    scopus 로고
    • Redox-coupled proton pumping in cytochrome c oxidase: Further insights from computer simulation
    • J.C. Xu, and G.A. Voth Redox-coupled proton pumping in cytochrome c oxidase: further insights from computer simulation Biochim. Biophys. Acta, Bioenerg. 1777 2008 196 201
    • (2008) Biochim. Biophys. Acta, Bioenerg. , vol.1777 , pp. 196-201
    • Xu, J.C.1    Voth, G.A.2
  • 77
    • 64849103999 scopus 로고    scopus 로고
    • a analysis of Glu286 in cytochrome c oxidase: Toward a calibrated molecular model
    • a analysis of Glu286 in cytochrome c oxidase: toward a calibrated molecular model Biochemistry 48 2009 2468 2485
    • (2009) Biochemistry , vol.48 , pp. 2468-2485
    • Ghosh, N.1    Prat-Resina, X.2    Gunner, M.R.3    Cui, Q.4
  • 78
    • 45549107077 scopus 로고    scopus 로고
    • Electrostatic basis for the unidirectionality of the primary proton transfer in cytochrome c oxidase
    • A.V. Pisliakov, P.K. Sharma, Z.T. Chu, M. Haranczyk, and A. Warshel Electrostatic basis for the unidirectionality of the primary proton transfer in cytochrome c oxidase Proc. Natl. Acad. Sci. U. S. A. 105 2008 7726 7731
    • (2008) Proc. Natl. Acad. Sci. U. S. A. , vol.105 , pp. 7726-7731
    • Pisliakov, A.V.1    Sharma, P.K.2    Chu, Z.T.3    Haranczyk, M.4    Warshel, A.5
  • 79
    • 77953770537 scopus 로고    scopus 로고
    • Variable proton-pumping stoichiometry in structural variants of cytochrome c oxidase
    • P. Brzezinski, and A.-L. Johansson Variable proton-pumping stoichiometry in structural variants of cytochrome c oxidase Biochim. Biophys. Acta, Bioenerg. 1797 2010 710 723
    • (2010) Biochim. Biophys. Acta, Bioenerg. , vol.1797 , pp. 710-723
    • Brzezinski, P.1    Johansson, A.-L.2
  • 80
    • 80052475923 scopus 로고    scopus 로고
    • Glu-286 rotation and water wire reorientation are unlikely the gating elements for proton pumping in cytochrome c oxidase
    • S. Yang, and Q. Cui Glu-286 rotation and water wire reorientation are unlikely the gating elements for proton pumping in cytochrome c oxidase Biophys. J. 101 2011 61 69
    • (2011) Biophys. J. , vol.101 , pp. 61-69
    • Yang, S.1    Cui, Q.2


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