A disintegrin and metalloenzyme (ADAM) 17 activation is regulated by α5β1 integrin in kidney mesangial cells

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  Gooz, Pal ^a   Dang, Yujing ^a   Higashiyama, Shigeki ^b   Twal, Waleed O ^a   Haycraft, Courtney J ^c   Gooz, Monika ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b EHIME UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAM 17 PROTEIN; ADAM PROTEIN; G PROTEIN COUPLED RECEPTOR; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; SEROTONIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 5; 5 (3 HYDROXYBENZOYL) 2 THIOPHENESULFONAMIDE; 5-(3-HYDROXYBENZOYL)-2-THIOPHENESULFONAMIDE; BETA1 INTEGRIN; HEPARIN-BINDING EGF-LIKE GROWTH FACTOR; MULTIPROTEIN COMPLEX; SIGNAL PEPTIDE; THIOPHENE DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME; TUMOR NECROSIS FACTOR-ALPHA CONVERTASE;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CHRONIC KIDNEY DISEASE; CONTROLLED STUDY; DISSOCIATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; GENE SILENCING; IMMUNOHISTOCHEMISTRY; MESANGIUM CELL; NONHUMAN; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; RAT; ANIMAL; CELL CULTURE; DRUG EFFECT; DRUG POTENTIATION; ENZYMOLOGY; METABOLISM; PROTEIN TRANSPORT; SPRAGUE DAWLEY RAT;

ADAM PROTEINS; ANIMALS; ANTIGENS, CD29; CELLS, CULTURED; ENZYME ACTIVATION; INTEGRIN ALPHA5BETA1; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MESANGIAL CELLS; MULTIPROTEIN COMPLEXES; PROTEIN BINDING; PROTEIN TRANSPORT; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, G-PROTEIN-COUPLED; THIOPHENES;

EID: 84857875546     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0033350     Document Type: Article

References (34)

1. Black RA, Rauch CT, Kozlosky CJ, Peschon JJ, Slack JL, et al. (1997) A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells. Nature 385: 729-733.
2. Moss ML, Jin SL, Milla ME, Bickett DM, Burkhart W, et al. (1997) Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha. Nature 385: 733-736.
3. Horiuchi K, Zhou HM, Kelly K, Manova K, Blobel CP, (2005) Evaluation of the contributions of ADAMs 9, 12, 15, 17, and 19 to heart development and ectodomain shedding of neuregulins beta1 and beta2. Dev Biol 283: 459-471.
4. Peschon JJ, Slack JL, Reddy P, Stocking KL, Sunnarborg SW, et al. (1998) An essential role for ectodomain shedding in mammalian development. Science 282: 1281-1284.
5. Buckley CA, Rouhani FN, Kaler M, Adamik B, Hawari FI, et al. (2005) Amino-terminal TACE prodomain attenuates TNFR2 cleavage independently of the cysteine switch. Am J Physiol Lung Cell Mol Physiol 288: L1132-1138.
6. Singh RJ, Mason JC, Lidington EA, Edwards DR, Nuttall RK, et al. (2005) Cytokine stimulated vascular cell adhesion molecule-1 (VCAM-1) ectodomain release is regulated by TIMP-3. Cardiovasc Res 67: 39-49.
7. Bozkulak EC, Weinmaster G, (2009) Selective use of ADAM10 and ADAM17 in activation of Notch1 signaling. Mol Cell Biol 29: 5679-5695.
8. Blobel CP, (2005) ADAMs: key components in EGFR signalling and development. Nat Rev Mol Cell Biol 6: 32-43.
9. Edwards DR, Handsley MM, Pennington CJ, (2008) The ADAM metalloproteinases. Mol Aspects Med 29: 258-289.
10. Dey M, Baldys A, Sumter DB, Gooz P, Luttrell LM, et al. (2010) Bradykinin decreases podocyte permeability through ADAM17-dependent epidermal growth factor receptor activation and zonula occludens-1 rearrangement. Journal of Pharmacology & Experimental Therapeutics 334: 775-783.
11. Gooz M, Gooz P, Luttrell LM, Raymond JR, (2006) 5-HT2A receptor induces ERK phosphorylation and proliferation through ADAM-17 tumor necrosis factor-alpha-converting enzyme (TACE) activation and heparin-bound epidermal growth factor-like growth factor (HB-EGF) shedding in mesangial cells. J Biol Chem 281: 21004-21012.
12. Gooz P, Gooz M, Baldys A, Hoffman S, (2009) ADAM-17 regulates endothelial cell morphology, proliferation, and in vitro angiogenesis. Biochem Biophys Res Commun 380: 33-38.
13. Boor P, Floege J, (2011) Chronic kidney disease growth factors in renal fibrosis. Clinical and experimental pharmacology & physiology 38: 391-400.
14. Kovesdy CP, Kalantar-Zadeh K, (2008) Novel targets and new potential: developments in the treatment of inflammation in chronic kidney disease. Expert opinion on investigational drugs 17: 451-467.
15. Chung AW, Yang HH, Sigrist MK, Brin G, Chum E, et al. (2009) Matrix metalloproteinase-2 and-9 exacerbate arterial stiffening and angiogenesis in diabetes and chronic kidney disease. Cardiovascular research 84: 494-504.
16. Sharma S, Sirin Y, Susztak K, (2011) The story of Notch and chronic kidney disease. Current opinion in nephrology and hypertension 20: 56-61.
17. Kassiri Z, Oudit GY, Kandalam V, Awad A, Wang X, et al. (2009) Loss of TIMP3 enhances interstitial nephritis and fibrosis. Journal of the American Society of Nephrology: JASN 20: 1223-1235.
18. Menghini R, Menini S, Amoruso R, Fiorentino L, Casagrande V, et al. (2009) Tissue inhibitor of metalloproteinase 3 deficiency causes hepatic steatosis and adipose tissue inflammation in mice. Gastroenterology 136: 663-672 e664.
19. Fiorentino L, Vivanti A, Cavalera M, Marzano V, Ronci M, et al. (2010) Increased tumor necrosis factor alpha-converting enzyme activity induces insulin resistance and hepatosteatosis in mice. Hepatology 51: 103-110.
20. Fan H, Turck CW, Derynck R, (2003) Characterization of growth factor-induced serine phosphorylation of tumor necrosis factor-alpha converting enzyme and of an alternatively translated polypeptide. J Biol Chem 278: 18617-18627.
21. Diaz-Rodriguez E, Montero JC, Esparis-Ogando A, Yuste L, Pandiella A, (2002) Extracellular signal-regulated kinase phosphorylates tumor necrosis factor alpha-converting enzyme at threonine 735: a potential role in regulated shedding. Mol Biol Cell 13: 2031-2044.
22. Bridges LC, Bowditch RD, (2005) ADAM-Integrin Interactions: potential integrin regulated ectodomain shedding activity. Curr Pharm Des 11: 837-847.
23. Bax DV, Messent AJ, Tart J, van Hoang M, Kott J, et al. (2004) Integrin alpha5beta1 and ADAM-17 interact in vitro and co-localize in migrating HeLa cells. J Biol Chem 279: 22377-22386.
24. Saha A, Backert S, Hammond CE, Gooz M, Smolka AJ, (2010) Helicobacter pylori CagL activates ADAM17 to induce repression of the gastric H, K-ATPase alpha subunit. Gastroenterology 139: 239-248.
25. Bridges LC, Hanson KR, Tani PH, Mather T, Bowditch RD, (2003) Integrin alpha4beta1-dependent adhesion to ADAM 28 (MDC-L) requires an extended surface of the disintegrin domain. Biochemistry 42: 3734-3741.
26. Prenzel N, Zwick E, Daub H, Leserer M, Abraham R, et al. (1999) EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF. Nature 402: 884-888.
27. Asakura M, Kitakaze M, Takashima S, Liao Y, Ishikura F, et al. (2002) Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: metalloproteinase inhibitors as a new therapy. Nature medicine 8: 35-40.
28. Hart S, Fischer OM, Prenzel N, Zwick-Wallasch E, Schneider M, et al. (2005) GPCR-induced migration of breast carcinoma cells depends on both EGFR signal transactivation and EGFR-independent pathways. Biological chemistry 386: 845-855.
29. Lautrette A, Li S, Alili R, Sunnarborg SW, Burtin M, et al. (2005) Angiotensin II and EGF receptor cross-talk in chronic kidney diseases: a new therapeutic approach. Nature medicine 11: 867-874.
30. Dey M, Baldys A, Sumter DB, Gooz P, Luttrell LM, et al. (2010) Bradykinin decreases podocyte permeability through ADAM17-dependent epidermal growth factor receptor activation and zonula occludens-1 rearrangement. The Journal of pharmacology and experimental therapeutics 334: 775-783.
31. Sahin U, Weskamp G, Zheng Y, Chesneau V, Horiuchi K, et al. (2006) A sensitive method to monitor ectodomain shedding of ligands of the epidermal growth factor receptor. Methods Mol Biol 327: 99-113.
32. Ruoslahti E, Yamaguchi Y, (1991) Proteoglycans as modulators of growth factor activities. Cell 64: 867-869.
33. Garnovskaya MN, Nebigil CG, Arthur JM, Spurney RF, Raymond JR, (1995) 5-Hydroxytryptamine2A receptors expressed in rat renal mesangial cells inhibit cyclic AMP accumulation. Mol Pharmacol 48: 230-237.
34. Saha A, Hammond CE, Trojanowska M, Smolka AJ, (2008) Helicobacter pylori-induced H,K-ATPase {alpha}-subunit gene repression is mediated by NF-{kappa}B p50 homodimer promoter binding. Am J Physiol Gastrointest Liver Physiol 294: G795-807.