메뉴 건너뛰기




Volumn 21, Issue 123, 2012, Pages 48-56

Recent advances in the pathogenesis and clinical evaluation of pulmonary fibrosis

Author keywords

Idiopathic pulmonary fibrosis; Interstitial lung disease; Multidisciplinary team meeting; Pathogenesis

Indexed keywords

CORTICOSTEROID; GELATINASE B; MATRILYSIN; NEUTROPHIL COLLAGENASE; PROTEIN KINASE B; SCATTER FACTOR; STROMELYSIN; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA;

EID: 84857869507     PISSN: 09059180     EISSN: 16000617     Source Type: Journal    
DOI: 10.1183/09059180.00007611     Document Type: Review
Times cited : (45)

References (120)
  • 1
    • 79952717349 scopus 로고    scopus 로고
    • An official ATS/ERS/JRS/ ALAT statement: Idiopathic pulmonary fibrosis: Evidence-based guidelines for diagnosis and management
    • Raghu G, Collard HR, Egan JJ, et al. An official ATS/ERS/JRS/ ALAT statement: idiopathic pulmonary fibrosis: evidence-based guidelines for diagnosis and management. Am J Respir Crit Care Med 2011; 183: 788-824.
    • (2011) Am J Respir Crit Care Med , vol.183 , pp. 788-824
    • Raghu, G.1    Collard, H.R.2    Egan, J.J.3
  • 2
    • 77951176799 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: A disease with similarities and links to cancer biology
    • Vancheri C, Failla M, Crimi N, et al. Idiopathic pulmonary fibrosis: a disease with similarities and links to cancer biology. Eur Respir J 2010; 35: 496-504.
    • (2010) Eur Respir J , vol.35 , pp. 496-504
    • Vancheri, C.1    Failla, M.2    Crimi, N.3
  • 3
    • 70349422341 scopus 로고    scopus 로고
    • Increased local expression of coagulation factor X contributes to the fibrotic response in human and murine lung injury
    • Scotton CJ, Krupiczojc MA, Königshoff M, et al. Increased local expression of coagulation factor X contributes to the fibrotic response in human and murine lung injury. J Clin Invest 2009; 119: 2550-2563.
    • (2009) J Clin Invest , vol.119 , pp. 2550-2563
    • Scotton, C.J.1    Krupiczojc, M.A.2    Königshoff, M.3
  • 4
    • 33744914050 scopus 로고    scopus 로고
    • Evolving concepts of apoptosis in idiopathic pulmonary fibrosis
    • Thannickal VJ, Horowitz JC. Evolving concepts of apoptosis in idiopathic pulmonary fibrosis. Proc Am Thorac Soc 2006; 3: 350-356.
    • (2006) Proc Am Thorac Soc , vol.3 , pp. 350-356
    • Thannickal, V.J.1    Horowitz, J.C.2
  • 5
    • 37549007538 scopus 로고    scopus 로고
    • Apoptosis in pulmonary fibrosis: Too much or not enough?
    • Fattman CL. Apoptosis in pulmonary fibrosis: too much or not enough? Antioxid Redox Signal 2008; 10: 379-385.
    • (2008) Antioxid Redox Signal , vol.10 , pp. 379-385
    • Fattman, C.L.1
  • 6
    • 69949114515 scopus 로고    scopus 로고
    • NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury
    • Hecker L, Vittal R, Jones T, et al. NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury. Nat Med 2009; 15: 1077-1081.
    • (2009) Nat Med , vol.15 , pp. 1077-1081
    • Hecker, L.1    Vittal, R.2    Jones, T.3
  • 7
    • 33744924735 scopus 로고    scopus 로고
    • Role of epithelial cells in idiopathic pulmonary fibrosis: From innocent targets to serial killers
    • Selman M, Pardo A. Role of epithelial cells in idiopathic pulmonary fibrosis: from innocent targets to serial killers. Proc Am Thorac Soc 2006; 3: 364-372.
    • (2006) Proc Am Thorac Soc , vol.3 , pp. 364-372
    • Selman, M.1    Pardo, A.2
  • 8
    • 17844384822 scopus 로고    scopus 로고
    • Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-beta1: Potential role in idiopathic pulmonary fibrosis
    • Willis BC, Liebler JM, Luby-Phelps K, et al. Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-beta1: potential role in idiopathic pulmonary fibrosis. Am J Pathol 2005; 166: 1321-1332.
    • (2005) Am J Pathol , vol.166 , pp. 1321-1332
    • Willis, B.C.1    Liebler, J.M.2    Luby-Phelps, K.3
  • 9
    • 59449090107 scopus 로고    scopus 로고
    • TGF-beta-induced epithelial to mesenchymal transition
    • Xu J, Lamouille S, Derynck R. TGF-beta-induced epithelial to mesenchymal transition. Cell Res 2009; 19: 156-172.
    • (2009) Cell Res , vol.19 , pp. 156-172
    • Xu, J.1    Lamouille, S.2    Derynck, R.3
  • 10
    • 33748375828 scopus 로고    scopus 로고
    • Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix
    • Kim KK, Kugler MC, Wolters PJ, et al. Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix. Proc Natl Acad Sci USA 2006; 103: 13180-13185.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 13180-13185
    • Kim, K.K.1    Kugler, M.C.2    Wolters, P.J.3
  • 11
    • 72949119709 scopus 로고    scopus 로고
    • SNAI transcription factors mediate epithelial-mesenchymal transition in lung fibrosis
    • Jayachandran A, Königshoff M, Yu H, et al. SNAI transcription factors mediate epithelial-mesenchymal transition in lung fibrosis. Thorax 2009; 64: 1053-1061.
    • (2009) Thorax , vol.64 , pp. 1053-1061
    • Jayachandran, A.1    Königshoff, M.2    Yu, H.3
  • 12
    • 77955399498 scopus 로고    scopus 로고
    • Inhibition and role of let-7d in idiopathic pulmonary fibrosis
    • Pandit KV, Corcoran D, Yousef H, et al. Inhibition and role of let-7d in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2010; 182: 220-229.
    • (2010) Am J Respir Crit Care Med , vol.182 , pp. 220-229
    • Pandit, K.V.1    Corcoran, D.2    Yousef, H.3
  • 13
    • 28144459814 scopus 로고    scopus 로고
    • High-dose acetylcysteine in idiopathic pulmonary fibrosis
    • Demedts M, Behr J, Buhl R, et al. High-dose acetylcysteine in idiopathic pulmonary fibrosis. N Engl J Med 2005; 353: 2229-2242.
    • (2005) N Engl J Med , vol.353 , pp. 2229-2242
    • Demedts, M.1    Behr, J.2    Buhl, R.3
  • 14
    • 73949096392 scopus 로고    scopus 로고
    • Lung function in idiopathic pulmonary fibrosis-extended analyses of the IFIGENIA trial
    • Behr J, Demedts M, Buhl R, et al. Lung function in idiopathic pulmonary fibrosis-extended analyses of the IFIGENIA trial. Respir Res 2009; 10: 101.
    • (2009) Respir Res , vol.10 , pp. 101
    • Behr, J.1    Demedts, M.2    Buhl, R.3
  • 16
    • 66349113736 scopus 로고    scopus 로고
    • Hepatocyte growth factor inhibits epithelial to myofibroblast transition in lung cells via Smad7
    • Shukla MN, Rose JL, Ray R, et al. Hepatocyte growth factor inhibits epithelial to myofibroblast transition in lung cells via Smad7. Am J Respir Cell Mol Biol 2009; 40: 643-653.
    • (2009) Am J Respir Cell Mol Biol , vol.40 , pp. 643-653
    • Shukla, M.N.1    Rose, J.L.2    Ray, R.3
  • 17
    • 48949117344 scopus 로고    scopus 로고
    • Fibrocytes are a potential source of lung fibroblasts in idiopathic pulmonary fibrosis
    • Andersson-Sjöland A, de Alba CG, Nihlberg K, et al. Fibrocytes are a potential source of lung fibroblasts in idiopathic pulmonary fibrosis. Int J Biochem Cell Biol 2008; 40: 2129-2140.
    • (2008) Int J Biochem Cell Biol , vol.40 , pp. 2129-2140
    • Andersson-Sjöland, A.1    de Alba, C.G.2    Nihlberg, K.3
  • 18
    • 70350738517 scopus 로고    scopus 로고
    • The role of circulating mesenchymal progenitor cells (fibrocytes) in the pathogenesis of pulmonary fibrosis
    • Strieter RM, Keeley EC, Hughes MA, et al. The role of circulating mesenchymal progenitor cells (fibrocytes) in the pathogenesis of pulmonary fibrosis. J Leukoc Biol 2009; 86: 1111-1118.
    • (2009) J Leukoc Biol , vol.86 , pp. 1111-1118
    • Strieter, R.M.1    Keeley, E.C.2    Hughes, M.A.3
  • 19
    • 4043055316 scopus 로고    scopus 로고
    • Circulating fibrocytes traffic to the lungs in response to CXCL12 and mediate fibrosis
    • Phillips RJ, Burdick MD, Hong K, et al. Circulating fibrocytes traffic to the lungs in response to CXCL12 and mediate fibrosis. J Clin Invest 2004; 114: 438-446.
    • (2004) J Clin Invest , vol.114 , pp. 438-446
    • Phillips, R.J.1    Burdick, M.D.2    Hong, K.3
  • 20
    • 77956338352 scopus 로고    scopus 로고
    • Investigation of bone marrow mesenchymal stem cells (BM MSCs) involvement in idiopathic pulmonary fibrosis (IPF)
    • Antoniou KM, Papadaki HA, Soufla G, et al. Investigation of bone marrow mesenchymal stem cells (BM MSCs) involvement in idiopathic pulmonary fibrosis (IPF). Respir Med 2010; 104: 1535-1542.
    • (2010) Respir Med , vol.104 , pp. 1535-1542
    • Antoniou, K.M.1    Papadaki, H.A.2    Soufla, G.3
  • 21
    • 0242500879 scopus 로고    scopus 로고
    • Aberrant Wnt/beta-catenin pathway activation in idiopathic pulmonary fibrosis
    • Chilosi M, Poletti V, Zamò A, et al. Aberrant Wnt/beta-catenin pathway activation in idiopathic pulmonary fibrosis. Am J Pathol 2003; 162: 1495-1502.
    • (2003) Am J Pathol , vol.162 , pp. 1495-1502
    • Chilosi, M.1    Poletti, V.2    Zamò, A.3
  • 22
    • 47749101725 scopus 로고    scopus 로고
    • Functional Wnt signaling is increased in idiopathic pulmonary fibrosis
    • Königshoff M, Balsara N, Pfaff EM, et al. Functional Wnt signaling is increased in idiopathic pulmonary fibrosis. PLoS One 2008; 3: e2142.
    • (2008) PLoS One , vol.e2142 , pp. 3
    • Königshoff, M.1    Balsara, N.2    Pfaff, E.M.3
  • 23
    • 65249088418 scopus 로고    scopus 로고
    • WNT1-inducible signaling protein-1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis
    • Königshoff M, Kramer M, Balsara N, et al. WNT1-inducible signaling protein-1 mediates pulmonary fibrosis in mice and is upregulated in humans with idiopathic pulmonary fibrosis. J Clin Invest 2009; 119: 772-787.
    • (2009) J Clin Invest , vol.119 , pp. 772-787
    • Königshoff, M.1    Kramer, M.2    Balsara, N.3
  • 24
    • 33745183811 scopus 로고    scopus 로고
    • vbeta6 integrin-dependent TGF-beta activation and promotes acute lung injury
    • Jenkins RG, Su X, Su G, et al. Ligation of protease-activated receptor 1 enhances alphavbeta6 integrin-dependent TGF-beta activation and promotes acute lung injury. J Clin Invest 2006; 116: 1606-1614.
    • (2006) J Clin Invest , vol.116 , pp. 1606-1614
    • Jenkins, R.G.1    Su, X.2    Su, G.3
  • 25
    • 65349145784 scopus 로고    scopus 로고
    • q
    • Xu MY, Porte J, Knox AJ, et al. Lysophosphatidic acid induces alphavbeta6 integrin-mediated TGF-beta activation via the LPA2 receptor and the small G protein G alphaq. Am J Pathol 2009; 174: 1264-1279.
    • (2009) Am J Pathol , vol.174 , pp. 1264-1279
    • Xu, M.Y.1    Porte, J.2    Knox, A.J.3
  • 26
    • 0033524949 scopus 로고    scopus 로고
    • The integrin alpha v beta 6 binds and activates latent TGF beta 1: A mechanism for regulating pulmonary inflammation and fibrosis
    • Munger JS, Huang X, Kawakatsu H, et al. The integrin alpha v beta 6 binds and activates latent TGF beta 1: a mechanism for regulating pulmonary inflammation and fibrosis. Cell 1999; 96: 319-328.
    • (1999) Cell , vol.96 , pp. 319-328
    • Munger, J.S.1    Huang, X.2    Kawakatsu, H.3
  • 27
    • 38049002642 scopus 로고    scopus 로고
    • vbeta6 prevents pulmonary fibrosis without exacerbating inflammation
    • Horan GS, Wood S, Ona V, et al. Partial inhibition of integrin alphavbeta6 prevents pulmonary fibrosis without exacerbating inflammation. Am J Respir Crit Care Med 2008; 177: 56-65.
    • (2008) Am J Respir Crit Care Med , vol.177 , pp. 56-65
    • Horan, G.S.1    Wood, S.2    Ona, V.3
  • 28
    • 37849008770 scopus 로고    scopus 로고
    • vbeta6, an activator of latent transforming growth factor-beta, prevents radiation-induced lung fibrosis
    • Puthawala K, Hadjiangelis N, Jacoby SC, et al. Inhibition of integrin alphavbeta6, an activator of latent transforming growth factor-beta, prevents radiation-induced lung fibrosis. Am J Respir Crit Care Med 2008; 177: 82-90.
    • (2008) Am J Respir Crit Care Med , vol.177 , pp. 82-90
    • Puthawala, K.1    Hadjiangelis, N.2    Jacoby, S.C.3
  • 29
    • 0036119338 scopus 로고    scopus 로고
    • Molecular, pharmacological and functional diversity of 5-HT receptors
    • Hoyer D, Hannon JP, Martin GR. Molecular, pharmacological and functional diversity of 5-HT receptors. Pharmacol Biochem Behav 2002; 71: 533-554.
    • (2002) Pharmacol Biochem Behav , vol.71 , pp. 533-554
    • Hoyer, D.1    Hannon, J.P.2    Martin, G.R.3
  • 30
    • 78149303247 scopus 로고    scopus 로고
    • Increased expression of 5-hydroxytryptamine2A/B receptors in idiopathic pulmonary fibrosis: A rationale for therapeutic intervention
    • Königshoff M, Dumitrascu R, Udalov S, et al. Increased expression of 5-hydroxytryptamine2A/B receptors in idiopathic pulmonary fibrosis: a rationale for therapeutic intervention. Thorax 2010; 65: 949-955.
    • (2010) Thorax , vol.65 , pp. 949-955
    • Königshoff, M.1    Dumitrascu, R.2    Udalov, S.3
  • 31
    • 33744970745 scopus 로고    scopus 로고
    • Transgenic mice over-expressing the 5-hydroxytryptamine transporter gene in smooth muscle develop pulmonary hypertension
    • Guignabert C, Izikki M, Tu LI, et al. Transgenic mice over-expressing the 5-hydroxytryptamine transporter gene in smooth muscle develop pulmonary hypertension. Circ Res 2006; 98: 1323-1330.
    • (2006) Circ Res , vol.98 , pp. 1323-1330
    • Guignabert, C.1    Izikki, M.2    Tu, L.I.3
  • 32
    • 23644461803 scopus 로고    scopus 로고
    • Oxidative stress in pulmonary fibrosis: A possible role for redox modulatory therapy
    • Kinnula VL, Fattman CL, Tan RJ, et al. Oxidative stress in pulmonary fibrosis: a possible role for redox modulatory therapy. Am J Respir Crit Care Med 2005; 172: 417-422.
    • (2005) Am J Respir Crit Care Med , vol.172 , pp. 417-422
    • Kinnula, V.L.1    Fattman, C.L.2    Tan, R.J.3
  • 33
    • 38049079133 scopus 로고    scopus 로고
    • Serum levels of oxidative stress as a marker of disease severity in idiopathic pulmonary fibrosis
    • Daniil ZD, Papageorgiou E, Koutsokera A, et al. Serum levels of oxidative stress as a marker of disease severity in idiopathic pulmonary fibrosis. Pulm Pharmacol Ther 2008; 21: 26-31.
    • (2008) Pulm Pharmacol Ther , vol.21 , pp. 26-31
    • Daniil, Z.D.1    Papageorgiou, E.2    Koutsokera, A.3
  • 34
    • 0029148261 scopus 로고
    • Increased oxidation of extracellular glutathione by bronchoalveolar inflammatory cells in diffuse fibrosing alveolitis
    • Behr J, Degenkolb B, Maier K, et al. Increased oxidation of extracellular glutathione by bronchoalveolar inflammatory cells in diffuse fibrosing alveolitis. Eur Respir J 1995; 8: 1286-1292.
    • (1995) Eur Respir J , vol.8 , pp. 1286-1292
    • Behr, J.1    Degenkolb, B.2    Maier, K.3
  • 35
    • 0024578662 scopus 로고
    • Glutathione deficiency in the epithelial lining fluid of the lower respiratory tract in idiopathic pulmonary fibrosis
    • Cantin AM, Hubbard RC, Crystal RG. Glutathione deficiency in the epithelial lining fluid of the lower respiratory tract in idiopathic pulmonary fibrosis. Am Rev Respir Dis 1989; 139: 370-372.
    • (1989) Am Rev Respir Dis , vol.139 , pp. 370-372
    • Cantin, A.M.1    Hubbard, R.C.2    Crystal, R.G.3
  • 36
    • 0031280268 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 is a potent inhibitor of glutathione synthesis in the lung epithelial cell line A549: Transcriptional effect on the GSH rate-limiting enzyme gamma-glutamylcysteine synthetase
    • Arsalane K, Dubois CM, Muanza T, et al. Transforming growth factor-beta1 is a potent inhibitor of glutathione synthesis in the lung epithelial cell line A549: transcriptional effect on the GSH rate-limiting enzyme gamma-glutamylcysteine synthetase. Am J Respir Cell Mol Biol 1997; 17: 599-607.
    • (1997) Am J Respir Cell Mol Biol , vol.17 , pp. 599-607
    • Arsalane, K.1    Dubois, C.M.2    Muanza, T.3
  • 37
    • 0031449645 scopus 로고    scopus 로고
    • Antioxidative and clinical effects of high-dose N-acetylcysteine in fibrosing alveolitis. Adjunctive therapy to maintenance immunosuppression
    • Behr J, Maier K, Degenkolb B, et al. Antioxidative and clinical effects of high-dose N-acetylcysteine in fibrosing alveolitis. Adjunctive therapy to maintenance immunosuppression. Am J Respir Crit Care Med 1997; 156: 1897-1901.
    • (1997) Am J Respir Crit Care Med , vol.156 , pp. 1897-1901
    • Behr, J.1    Maier, K.2    Degenkolb, B.3
  • 38
    • 0036014536 scopus 로고    scopus 로고
    • Intracellular glutathione and bronchoalveolar cells in fibrosing alveolitis: Effects of N-acetylcysteine
    • Behr J, Degenkolb B, Krombach F, et al. Intracellular glutathione and bronchoalveolar cells in fibrosing alveolitis: effects of N-acetylcysteine. Eur Respir J 2002; 19: 906-911.
    • (2002) Eur Respir J , vol.19 , pp. 906-911
    • Behr, J.1    Degenkolb, B.2    Krombach, F.3
  • 39
    • 0035198813 scopus 로고    scopus 로고
    • Ceramide-mediated apoptosis in lung epithelial cells is regulated by glutathione
    • Lavrentiadou SN, Chan C, Kawcak T, et al. Ceramide-mediated apoptosis in lung epithelial cells is regulated by glutathione. Am J Respir Cell Mol Biol 2001; 25: 676-684.
    • (2001) Am J Respir Cell Mol Biol , vol.25 , pp. 676-684
    • Lavrentiadou, S.N.1    Chan, C.2    Kawcak, T.3
  • 40
    • 71249107919 scopus 로고    scopus 로고
    • N-acetyl-L-cysteine inhibits TGF-beta1-induced profibrotic responses in fibroblasts
    • Sugiura H, Ichikawa T, Liu X, et al. N-acetyl-L-cysteine inhibits TGF-beta1-induced profibrotic responses in fibroblasts. Pulm Pharmacol Ther 2009; 22: 487-491.
    • (2009) Pulm Pharmacol Ther , vol.22 , pp. 487-491
    • Sugiura, H.1    Ichikawa, T.2    Liu, X.3
  • 41
    • 77950829907 scopus 로고    scopus 로고
    • N-acetylcysteine inhibits IL-8 and MMP-9 release and ICAM-1 expression by bronchoalveolar cells from interstitial lung disease patients
    • Radomska-Leśniewska DM, Skopińska-Rózewska E, Jankowska-Steifer E, et al. N-acetylcysteine inhibits IL-8 and MMP-9 release and ICAM-1 expression by bronchoalveolar cells from interstitial lung disease patients. Pharmacol Rep 2010; 62: 131-138.
    • (2010) Pharmacol Rep , vol.62 , pp. 131-138
    • Radomska-Leśniewska, D.M.1    Skopińska-Rózewska, E.2    Jankowska-Steifer, E.3
  • 42
    • 77955881563 scopus 로고    scopus 로고
    • Diminished prostaglan-din E2 contributes to the apoptosis paradox in idiopathic pulmonary fibrosis
    • Maher TM, Evans IC, Bottoms SE, et al. Diminished prostaglan-din E2 contributes to the apoptosis paradox in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2010; 182: 73-82.
    • (2010) Am J Respir Crit Care Med , vol.182 , pp. 73-82
    • Maher, T.M.1    Evans, I.C.2    Bottoms, S.E.3
  • 43
    • 70349115049 scopus 로고    scopus 로고
    • Endothelin-1 and transforming growth factor-beta1 independently induce fibro-blast resistance to apoptosis via AKT activation
    • Kulasekaran P, Scavone CA, Rogers DS, et al. Endothelin-1 and transforming growth factor-beta1 independently induce fibro-blast resistance to apoptosis via AKT activation. Am J Respir Cell Mol Biol 2009; 41: 484-493.
    • (2009) Am J Respir Cell Mol Biol , vol.41 , pp. 484-493
    • Kulasekaran, P.1    Scavone, C.A.2    Rogers, D.S.3
  • 44
    • 30344485686 scopus 로고    scopus 로고
    • Negative regulation of myofibroblast differentiation by PTEN (Phosphatase and Tensin Homolog Deleted on chromosome 10)
    • White ES, Atrasz RG, Hu B, et al. Negative regulation of myofibroblast differentiation by PTEN (Phosphatase and Tensin Homolog Deleted on chromosome 10). Am J Respir Crit Care Med 2006; 173: 112-121.
    • (2006) Am J Respir Crit Care Med , vol.173 , pp. 112-121
    • White, E.S.1    Atrasz, R.G.2    Hu, B.3
  • 45
    • 36248962699 scopus 로고    scopus 로고
    • Dendritic cells accumulate in human fibrotic interstitial lung disease
    • Marchal-Sommé J, Uzunhan Y, Marchand-Adam S, et al. Dendritic cells accumulate in human fibrotic interstitial lung disease. Am J Respir Crit Care Med 2007; 176: 1007-1014.
    • (2007) Am J Respir Crit Care Med , vol.176 , pp. 1007-1014
    • Marchal-Sommé, J.1    Uzunhan, Y.2    Marchand-Adam, S.3
  • 46
    • 33646481327 scopus 로고    scopus 로고
    • Cutting edge: Nonproliferating mature immune cells form a novel type of organized lymphoid structure in idiopathic pulmonary fibrosis
    • Marchal-Sommé J, Uzunhan Y, Marchand-Adam S, et al. Cutting edge: nonproliferating mature immune cells form a novel type of organized lymphoid structure in idiopathic pulmonary fibrosis. J Immunol 2006; 176: 5735-5739.
    • (2006) J Immunol , vol.176 , pp. 5735-5739
    • Marchal-Sommé, J.1    Uzunhan, Y.2    Marchand-Adam, S.3
  • 47
    • 34848884629 scopus 로고    scopus 로고
    • Cellular and humoral autoreactivity in idiopathic pulmonary fibrosis
    • Feghali-Bostwick CA, Tsai CG, Valentine VG, et al. Cellular and humoral autoreactivity in idiopathic pulmonary fibrosis. J Immunol 2007; 179: 2592-2599.
    • (2007) J Immunol , vol.179 , pp. 2592-2599
    • Feghali-Bostwick, C.A.1    Tsai, C.G.2    Valentine, V.G.3
  • 48
    • 79952719285 scopus 로고    scopus 로고
    • Identification of periplakin as a new target for autoreactivity in idiopathic pulmonary fibrosis
    • Taillé C, Grootenboer-Mignot S, Boursier C, et al. Identification of periplakin as a new target for autoreactivity in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2011; 183: 759-766.
    • (2011) Am J Respir Crit Care Med , vol.183 , pp. 759-766
    • Taillé, C.1    Grootenboer-Mignot, S.2    Boursier, C.3
  • 49
    • 52949084684 scopus 로고    scopus 로고
    • Factor Xa: At the crossroads between coagulation and signaling in physiology and disease
    • Borensztajn K, Peppelenbosch MP, Spek CA. Factor Xa: at the crossroads between coagulation and signaling in physiology and disease. Trends Mol Med 2008; 14: 429-440.
    • (2008) Trends Mol Med , vol.14 , pp. 429-440
    • Borensztajn, K.1    Peppelenbosch, M.P.2    Spek, C.A.3
  • 50
    • 0032126368 scopus 로고    scopus 로고
    • Thrombin stimulates fibroblast procollagen production via proteolytic activation of protease-activated receptor 1
    • Chambers RC, Dabbagh K, McAnulty RJ, et al. Thrombin stimulates fibroblast procollagen production via proteolytic activation of protease-activated receptor 1. Biochem J 1998; 333: 121-127.
    • (1998) Biochem J , vol.333 , pp. 121-127
    • Chambers, R.C.1    Dabbagh, K.2    McAnulty, R.J.3
  • 51
    • 63349085645 scopus 로고    scopus 로고
    • Pulmonary epithelium is a prominent source of proteinase-activated receptor-1-inducible CCL2 in pulmonary fibrosis
    • Mercer PF, Johns RH, Scotton CJ, et al. Pulmonary epithelium is a prominent source of proteinase-activated receptor-1-inducible CCL2 in pulmonary fibrosis. Am J Respir Crit Care Med 2009; 179: 414-425.
    • (2009) Am J Respir Crit Care Med , vol.179 , pp. 414-425
    • Mercer, P.F.1    Johns, R.H.2    Scotton, C.J.3
  • 52
    • 0034634622 scopus 로고    scopus 로고
    • Thrombin is a potent inducer of connective tissue growth factor production via proteolytic activation of protease-activated receptor-1
    • Chambers RC, Leoni P, Blanc-Brude OP, et al. Thrombin is a potent inducer of connective tissue growth factor production via proteolytic activation of protease-activated receptor-1. J Biol Chem 2000; 275: 35584-35591.
    • (2000) J Biol Chem , vol.275 , pp. 35584-35591
    • Chambers, R.C.1    Leoni, P.2    Blanc-Brude, O.P.3
  • 53
    • 2942644636 scopus 로고    scopus 로고
    • Inter-observer variation between pathologists in diffuse parenchymal lung disease
    • Nicholson AG, Addis BJ, Bharucha H, et al. Inter-observer variation between pathologists in diffuse parenchymal lung disease. Thorax 2004; 59: 500-505.
    • (2004) Thorax , vol.59 , pp. 500-505
    • Nicholson, A.G.1    Addis, B.J.2    Bharucha, H.3
  • 54
    • 0035508478 scopus 로고    scopus 로고
    • Histopathologic variability in usual and nonspecific interstitial pneumonias
    • Flaherty KR, Travis WD, Colby TV, et al. Histopathologic variability in usual and nonspecific interstitial pneumonias. Am J Respir Crit Care Med 2001; 164: 1722-1727.
    • (2001) Am J Respir Crit Care Med , vol.164 , pp. 1722-1727
    • Flaherty, K.R.1    Travis, W.D.2    Colby, T.V.3
  • 55
    • 1242351701 scopus 로고    scopus 로고
    • Prognostic implications of histologic patterns in multiple surgical lung biopsies from patients with idiopathic interstitial pneumonias
    • Monaghan H, Wells AU, Colby TV, et al. Prognostic implications of histologic patterns in multiple surgical lung biopsies from patients with idiopathic interstitial pneumonias. Chest 2004; 125: 522-526.
    • (2004) Chest , vol.125 , pp. 522-526
    • Monaghan, H.1    Wells, A.U.2    Colby, T.V.3
  • 56
    • 5144222998 scopus 로고    scopus 로고
    • Idiopathic interstitial pneumonia: What is the effect of a multidisciplinary approach to diagnosis?
    • Flaherty KR, King TE, Raghu G, et al. Idiopathic interstitial pneumonia: what is the effect of a multidisciplinary approach to diagnosis? Am J Respir Crit Care Med 2004; 170: 904-910.
    • (2004) Am J Respir Crit Care Med , vol.170 , pp. 904-910
    • Flaherty, K.R.1    King, T.E.2    Raghu, G.3
  • 57
    • 0035185842 scopus 로고    scopus 로고
    • Nonspecific interstitial pneumonia and usual interstitial pneumonia: Comparative appearances at and diagnostic accuracy of thin-section CT
    • MacDonald SL, Rubens MB, Hansell DM, et al. Nonspecific interstitial pneumonia and usual interstitial pneumonia: comparative appearances at and diagnostic accuracy of thin-section CT. Radiology 2001; 221: 600-605.
    • (2001) Radiology , vol.221 , pp. 600-605
    • Macdonald, S.L.1    Rubens, M.B.2    Hansell, D.M.3
  • 58
    • 63849343420 scopus 로고    scopus 로고
    • Pivotal clinical dilemmas in collagen vascular diseases associated with interstitial lung involvement
    • Antoniou KM, Margaritopoulos G, Economidou F, et al. Pivotal clinical dilemmas in collagen vascular diseases associated with interstitial lung involvement. Eur Respir J 2009; 33: 882-896.
    • (2009) Eur Respir J , vol.33 , pp. 882-896
    • Antoniou, K.M.1    Margaritopoulos, G.2    Economidou, F.3
  • 59
    • 77957948534 scopus 로고    scopus 로고
    • Diffuse interstitial lung disease: Overlaps and uncertainties
    • Walsh SL, Hansell DM. Diffuse interstitial lung disease: overlaps and uncertainties. Eur Radiol 2010; 20: 1859-1867.
    • (2010) Eur Radiol , vol.20 , pp. 1859-1867
    • Walsh, S.L.1    Hansell, D.M.2
  • 60
    • 0032717980 scopus 로고    scopus 로고
    • Respiratory bronchio-litis, respiratory bronchiolitis-associated interstitial lung disease, and desquamative interstitial pneumonia: Different entities or part of the spectrum of the same disease process?
    • Heyneman LE, Ward S, Lynch DA, et al. Respiratory bronchio-litis, respiratory bronchiolitis-associated interstitial lung disease, and desquamative interstitial pneumonia: different entities or part of the spectrum of the same disease process? AJR Am J Roentgenol 1999; 173: 1617-1622.
    • (1999) AJR Am J Roentgenol , vol.173 , pp. 1617-1622
    • Heyneman, L.E.1    Ward, S.2    Lynch, D.A.3
  • 62
    • 0029066559 scopus 로고
    • Nonspecific interstitial pneumonia with fibrosis: Radiographic and CT findings in seven patients
    • Park JS, Lee KS, Kim JS, et al. Nonspecific interstitial pneumonia with fibrosis: radiographic and CT findings in seven patients. Radiology 1995; 195: 645-648.
    • (1995) Radiology , vol.195 , pp. 645-648
    • Park, J.S.1    Lee, K.S.2    Kim, J.S.3
  • 63
    • 0031793935 scopus 로고    scopus 로고
    • Nonspecific interstitial pneumonia. Individualization of a clinicopathologic entity in a series of 12 patients
    • Cottin V, Donsbeck AV, Revel D, et al. Nonspecific interstitial pneumonia. Individualization of a clinicopathologic entity in a series of 12 patients. Am J Respir Crit Care Med 1998; 158: 1286-1293.
    • (1998) Am J Respir Crit Care Med , vol.158 , pp. 1286-1293
    • Cottin, V.1    Donsbeck, A.V.2    Revel, D.3
  • 64
    • 0025274632 scopus 로고
    • Interstitial lung disease in polymyositis and dermatomyositis. Clinical features and prognosis as correlated with histologic findings
    • Tazelaar HD, Viggiano RW, Pickersgill J, et al. Interstitial lung disease in polymyositis and dermatomyositis. Clinical features and prognosis as correlated with histologic findings. Am Rev Respir Dis 1990; 141: 727-733.
    • (1990) Am Rev Respir Dis , vol.141 , pp. 727-733
    • Tazelaar, H.D.1    Viggiano, R.W.2    Pickersgill, J.3
  • 65
    • 0030845006 scopus 로고    scopus 로고
    • Pulmonary involvement in polymyositis and dermatomyositis: Sequential evaluation with CT
    • Mino M, Noma S, Taguchi Y, et al. Pulmonary involvement in polymyositis and dermatomyositis: sequential evaluation with CT. AJR Am J Roentgenol 1997; 169: 83-87.
    • (1997) AJR Am J Roentgenol , vol.169 , pp. 83-87
    • Mino, M.1    Noma, S.2    Taguchi, Y.3
  • 66
    • 78349261541 scopus 로고    scopus 로고
    • Alveolar proteinosis with hypersensitivity pneumonitis: A new clinical phenotype
    • Verma H, Nicholson AG, Kerr KM, et al. Alveolar proteinosis with hypersensitivity pneumonitis: a new clinical phenotype. Respirology 2010; 15: 1197-1202.
    • (2010) Respirology , vol.15 , pp. 1197-1202
    • Verma, H.1    Nicholson, A.G.2    Kerr, K.M.3
  • 67
    • 0031934678 scopus 로고    scopus 로고
    • The significance of bronchial dilatation on CT in patients with adult respiratory distress syndrome
    • Howling SJ, Evans TW, Hansell DM. The significance of bronchial dilatation on CT in patients with adult respiratory distress syndrome. Clin Radiol 1998; 53: 105-109.
    • (1998) Clin Radiol , vol.53 , pp. 105-109
    • Howling, S.J.1    Evans, T.W.2    Hansell, D.M.3
  • 68
    • 0028140298 scopus 로고
    • Nonspecific interstitial pneumonia/ fibrosis. Histologic features and clinical significance
    • Katzenstein AL, Fiorelli RF. Nonspecific interstitial pneumonia/ fibrosis. Histologic features and clinical significance. Am J Surg Pathol 1994; 18: 136-147.
    • (1994) Am J Surg Pathol , vol.18 , pp. 136-147
    • Katzenstein, A.L.1    Fiorelli, R.F.2
  • 69
    • 78449269444 scopus 로고    scopus 로고
    • The clinical utility of bronchoalveolar lavage in diffuse parenchymal lung disease
    • Wells AU. The clinical utility of bronchoalveolar lavage in diffuse parenchymal lung disease. Eur Respir Rev 2010; 19: 237-241.
    • (2010) Eur Respir Rev , vol.19 , pp. 237-241
    • Wells, A.U.1
  • 70
    • 80053557379 scopus 로고    scopus 로고
    • Bronchoalveolar lavage for the evaluation of interstitial lung disease: Is it clinically useful?
    • Meyer KC, Raghu G. Bronchoalveolar lavage for the evaluation of interstitial lung disease: is it clinically useful? Eur Respir J 2011; 38: 761-769.
    • (2011) Eur Respir J , vol.38 , pp. 761-769
    • Meyer, K.C.1    Raghu, G.2
  • 71
    • 66249145452 scopus 로고    scopus 로고
    • Significance of broncho-alveolar lavage for the diagnosis of idiopathic pulmonary fibrosis
    • Ohshimo S, Bonella F, Cui A, et al. Significance of broncho-alveolar lavage for the diagnosis of idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2009; 179: 1043-1047.
    • (2009) Am J Respir Crit Care Med , vol.179 , pp. 1043-1047
    • Ohshimo, S.1    Bonella, F.2    Cui, A.3
  • 72
    • 0018830853 scopus 로고
    • Pulmonary alveolar proteinosis: The diagnosis by segmental lavage
    • Martin RJ, Coalson JJ, Rogers RM, et al. Pulmonary alveolar proteinosis: the diagnosis by segmental lavage. Am Rev Respir Dis 1980; 121: 819-825.
    • (1980) Am Rev Respir Dis , vol.121 , pp. 819-825
    • Martin, R.J.1    Coalson, J.J.2    Rogers, R.M.3
  • 73
    • 0028118882 scopus 로고
    • Establishing diagnosis of pulmonary malignant lymphoma by gene rearrangement analysis of lymphocytes in bronchoalveolar lavage fluid
    • Betsuyaku T, Munakata M, Yamaguchi E, et al. Establishing diagnosis of pulmonary malignant lymphoma by gene rearrangement analysis of lymphocytes in bronchoalveolar lavage fluid. Am J Respir Crit Care Med 1994; 149: 526-529.
    • (1994) Am J Respir Crit Care Med , vol.149 , pp. 526-529
    • Betsuyaku, T.1    Munakata, M.2    Yamaguchi, E.3
  • 74
    • 0035880162 scopus 로고    scopus 로고
    • Utility of a lung biopsy for the diagnosis of idiopathic pulmonary fibrosis
    • Hunninghake GW, Zimmerman MB, Schwartz DA, et al. Utility of a lung biopsy for the diagnosis of idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2001; 164: 193-196.
    • (2001) Am J Respir Crit Care Med , vol.164 , pp. 193-196
    • Hunninghake, G.W.1    Zimmerman, M.B.2    Schwartz, D.A.3
  • 75
    • 0032725125 scopus 로고    scopus 로고
    • The accuracy of the clinical diagnosis of new-onset idiopathic pulmonary fibrosis and other interstitial lung disease: A prospective study
    • Raghu G, Mageto YN, Lockhart D, et al. The accuracy of the clinical diagnosis of new-onset idiopathic pulmonary fibrosis and other interstitial lung disease: a prospective study. Chest 1999; 116: 1168-1174.
    • (1999) Chest , vol.116 , pp. 1168-1174
    • Raghu, G.1    Mageto, Y.N.2    Lockhart, D.3
  • 76
    • 79958245658 scopus 로고    scopus 로고
    • Towards a better diagnosis of idiopathic pulmonary fibrosis
    • Valeyre D. Towards a better diagnosis of idiopathic pulmonary fibrosis. Eur Respir Rev 2011; 20: 108-113.
    • (2011) Eur Respir Rev , vol.20 , pp. 108-113
    • Valeyre, D.1
  • 77
    • 51549101867 scopus 로고    scopus 로고
    • Interstitial lung disease guideline: The British Thoracic Society in collaboration with the Thoracic Society of Australia and New Zealand and the Irish Thoracic Society
    • Bradley B, Branley HM, Egan JJ, et al. Interstitial lung disease guideline: the British Thoracic Society in collaboration with the Thoracic Society of Australia and New Zealand and the Irish Thoracic Society. Thorax 2008; 63: Suppl. 5, v1-v58.
    • (2008) Thorax , vol.63 , Issue.SUPPL. 5
    • Bradley, B.1    Branley, H.M.2    Egan, J.J.3
  • 78
    • 77953077453 scopus 로고    scopus 로고
    • Clinical predictors of a diagnosis of idiopathic pulmonary fibrosis
    • Fell CD, Martinez FJ, Liu LX, et al. Clinical predictors of a diagnosis of idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2010; 181: 832-837.
    • (2010) Am J Respir Crit Care Med , vol.181 , pp. 832-837
    • Fell, C.D.1    Martinez, F.J.2    Liu, L.X.3
  • 79
    • 77957967906 scopus 로고    scopus 로고
    • Lung disease
    • In: Albert RK, Spiro SG, Jett JR, eds., 3rd Edn. London, Mosby
    • Wells AU. Lung disease. In: Albert RK, Spiro SG, Jett JR, eds. Clinical Respiratory Medicine. 3rd Edn. London, Mosby, 2008; pp. 655-666.
    • (2008) Clinical Respiratory Medicine , pp. 655-666
    • Wells, A.U.1
  • 80
    • 44449152061 scopus 로고    scopus 로고
    • Interstitial lung disease in systemic sclerosis: A simple staging system
    • Goh NS, Desai SR, Veeraraghavan S, et al. Interstitial lung disease in systemic sclerosis: a simple staging system. Am J Respir Crit Care Med 2008; 177: 1248-1254.
    • (2008) Am J Respir Crit Care Med , vol.177 , pp. 1248-1254
    • Goh, N.S.1    Desai, S.R.2    Veeraraghavan, S.3
  • 81
    • 38349039634 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: Outcome in relation to smoking status
    • Antoniou KM, Hansell DM, Rubens MB, et al. Idiopathic pulmonary fibrosis: outcome in relation to smoking status. Am J Respir Crit Care Med 2008; 177: 190-194.
    • (2008) Am J Respir Crit Care Med , vol.177 , pp. 190-194
    • Antoniou, K.M.1    Hansell, D.M.2    Rubens, M.B.3
  • 82
    • 26844449508 scopus 로고    scopus 로고
    • Combined pulmonary fibrosis and emphysema: A distinct underrecognised entity
    • Cottin V, Nunes H, Brillet PY, et al. Combined pulmonary fibrosis and emphysema: a distinct underrecognised entity. Eur Respir J 2005; 26: 586-593.
    • (2005) Eur Respir J , vol.26 , pp. 586-593
    • Cottin, V.1    Nunes, H.2    Brillet, P.Y.3
  • 83
    • 67650786507 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis and emphysema: Decreased survival associated with severe pulmonary arterial hypertension
    • Mejía M, Carrillo G, Rojas-Serrano J, et al. Idiopathic pulmonary fibrosis and emphysema: decreased survival associated with severe pulmonary arterial hypertension. Chest 2009; 136: 10-15.
    • (2009) Chest , vol.136 , pp. 10-15
    • Mejía, M.1    Carrillo, G.2    Rojas-Serrano, J.3
  • 84
    • 75149155845 scopus 로고    scopus 로고
    • Pulmonary hypertension in patients with combined pulmonary fibrosis and emphysema syndrome
    • Cottin V, Le Pavec J, Prévot G, et al. Pulmonary hypertension in patients with combined pulmonary fibrosis and emphysema syndrome. Eur Respir J 2010; 35: 105-111.
    • (2010) Eur Respir J , vol.35 , pp. 105-111
    • Cottin, V.1    le Pavec, J.2    Prévot, G.3
  • 85
    • 76149105846 scopus 로고    scopus 로고
    • Smoking-related lung diseases: A clinical perspective
    • Balbi B, Cottin V, Singh S, et al. Smoking-related lung diseases: a clinical perspective. Eur Respir J 2010; 35: 231-233.
    • (2010) Eur Respir J , vol.35 , pp. 231-233
    • Balbi, B.1    Cottin, V.2    Singh, S.3
  • 86
    • 78650783836 scopus 로고    scopus 로고
    • Combined pulmonary fibrosis and emphysema syndrome in connective tissue disease
    • Cottin V, Nunes H, Mouthon L, et al. Combined pulmonary fibrosis and emphysema syndrome in connective tissue disease. Arthritis Rheum 2011; 63: 295-304.
    • (2011) Arthritis Rheum , vol.63 , pp. 295-304
    • Cottin, V.1    Nunes, H.2    Mouthon, L.3
  • 87
    • 0032433225 scopus 로고    scopus 로고
    • Increased prevalence of gastroesophageal reflux in patients with idiopathic pulmonary fibrosis
    • Tobin RW, Pope CE 2nd, Pellegrini CA, et al. Increased prevalence of gastroesophageal reflux in patients with idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 1998; 158: 1804-1808.
    • (1998) Am J Respir Crit Care Med , vol.158 , pp. 1804-1808
    • Tobin, R.W.1    Pope, C.E.2    Pellegrini, C.A.3
  • 88
    • 30744455313 scopus 로고    scopus 로고
    • High prevalence of abnormal acid gastro-oesophageal reflux in idiopathic pulmonary fibrosis
    • Raghu G, Freudenberger TD, Yang S, et al. High prevalence of abnormal acid gastro-oesophageal reflux in idiopathic pulmonary fibrosis. Eur Respir J 2006; 27: 136-142.
    • (2006) Eur Respir J , vol.27 , pp. 136-142
    • Raghu, G.1    Freudenberger, T.D.2    Yang, S.3
  • 89
    • 79951950906 scopus 로고    scopus 로고
    • Progression of idiopathic pulmonary fibrosis: Lessons from asymmetrical disease
    • Tcherakian C, Cottin V, Brillet PY, et al. Progression of idiopathic pulmonary fibrosis: lessons from asymmetrical disease. Thorax 2011; 66: 226-231.
    • (2011) Thorax , vol.66 , pp. 226-231
    • Tcherakian, C.1    Cottin, V.2    Brillet, P.Y.3
  • 90
    • 79951947819 scopus 로고    scopus 로고
    • If it was good enough for Aristotle
    • Maher TM, Wells AU. If it was good enough for Aristotle. Thorax 2011; 66: 183-184.
    • (2011) Thorax , vol.66 , pp. 183-184
    • Maher, T.M.1    Wells, A.U.2
  • 91
    • 30144438578 scopus 로고    scopus 로고
    • The impact of pulmonary hypertension on survival in patients with idiopathic pulmonary fibrosis
    • Nadrous HF, Pellikka PA, Krowka MJ, et al. The impact of pulmonary hypertension on survival in patients with idiopathic pulmonary fibrosis. Chest 2005; 128: Suppl. 6, 616S-617S.
    • (2005) Chest , vol.128 , Issue.SUPPL. 6
    • Nadrous, H.F.1    Pellikka, P.A.2    Krowka, M.J.3
  • 92
    • 33947370516 scopus 로고    scopus 로고
    • Significance of pulmonary arterial pressure and diffusion capacity of the lung as prog-nosticator in patients with idiopathic pulmonary fibrosis
    • Hamada K, Nagai S, Tanaka S, et al. Significance of pulmonary arterial pressure and diffusion capacity of the lung as prog-nosticator in patients with idiopathic pulmonary fibrosis. Chest 2007; 131: 650-656.
    • (2007) Chest , vol.131 , pp. 650-656
    • Hamada, K.1    Nagai, S.2    Tanaka, S.3
  • 93
    • 33645118315 scopus 로고    scopus 로고
    • Prevalence and outcomes of pulmonary arterial hypertension in advanced idiopathic pulmonary fibrosis
    • Lettieri CJ, Nathan SD, Barnett SD, et al. Prevalence and outcomes of pulmonary arterial hypertension in advanced idiopathic pulmonary fibrosis. Chest 2006; 129: 746-752.
    • (2006) Chest , vol.129 , pp. 746-752
    • Lettieri, C.J.1    Nathan, S.D.2    Barnett, S.D.3
  • 94
    • 27144547143 scopus 로고    scopus 로고
    • Pulmonary hypertension in patients with idiopathic pulmonary fibrosis
    • Nadrous HF, Pellikka PA, Krowka MJ, et al. Pulmonary hypertension in patients with idiopathic pulmonary fibrosis. Chest 2005; 128: 2393-2399.
    • (2005) Chest , vol.128 , pp. 2393-2399
    • Nadrous, H.F.1    Pellikka, P.A.2    Krowka, M.J.3
  • 95
    • 38449102031 scopus 로고    scopus 로고
    • Pulmonary hypertension in patients with pulmonary fibrosis awaiting lung transplant
    • Shorr AF, Wainright JL, Cors CS, et al. Pulmonary hypertension in patients with pulmonary fibrosis awaiting lung transplant. Eur Respir J 2007; 30: 715-721.
    • (2007) Eur Respir J , vol.30 , pp. 715-721
    • Shorr, A.F.1    Wainright, J.L.2    Cors, C.S.3
  • 96
    • 32944476373 scopus 로고    scopus 로고
    • Noninvasive estimation of clinically asymptomatic pulmonary hypertension in idiopathic pulmonary fibrosis
    • Agarwal R, Gupta D, Verma JS, et al. Noninvasive estimation of clinically asymptomatic pulmonary hypertension in idiopathic pulmonary fibrosis. Indian J Chest Dis Allied Sci 2005; 47: 267-271.
    • (2005) Indian J Chest Dis Allied Sci , vol.47 , pp. 267-271
    • Agarwal, R.1    Gupta, D.2    Verma, J.S.3
  • 97
    • 53149152248 scopus 로고    scopus 로고
    • Serial development of pulmonary hypertension in patients with idiopathic pulmonary fibrosis
    • Nathan SD, Shlobin OA, Ahmad S, et al. Serial development of pulmonary hypertension in patients with idiopathic pulmonary fibrosis. Respiration 2008; 76: 288-294.
    • (2008) Respiration , vol.76 , pp. 288-294
    • Nathan, S.D.1    Shlobin, O.A.2    Ahmad, S.3
  • 98
    • 18744381053 scopus 로고    scopus 로고
    • Pulmonary hypertension in advanced sarcoidosis: Epidemiology and clinical characteristics
    • Shorr AF, Helman DL, Davies DB, et al. Pulmonary hypertension in advanced sarcoidosis: epidemiology and clinical characteristics. Eur Respir J 2005; 25: 783-788.
    • (2005) Eur Respir J , vol.25 , pp. 783-788
    • Shorr, A.F.1    Helman, D.L.2    Davies, D.B.3
  • 99
    • 70349673627 scopus 로고    scopus 로고
    • Pulmonary vascular resistance predicts early mortality in patients with diffuse fibrotic lung disease and suspected pulmonary hypertension
    • Corte TJ, Wort SJ, Gatzoulis MA, et al. Pulmonary vascular resistance predicts early mortality in patients with diffuse fibrotic lung disease and suspected pulmonary hypertension. Thorax 2009; 64: 883-888.
    • (2009) Thorax , vol.64 , pp. 883-888
    • Corte, T.J.1    Wort, S.J.2    Gatzoulis, M.A.3
  • 100
    • 58249092608 scopus 로고    scopus 로고
    • Echocardiography and brain natriuretic peptide as prognostic indicators in idiopathic pulmonary fibrosis
    • Song JW, Song JK, Kim DS. Echocardiography and brain natriuretic peptide as prognostic indicators in idiopathic pulmonary fibrosis. Respir Med 2009; 103: 180-186.
    • (2009) Respir Med , vol.103 , pp. 180-186
    • Song, J.W.1    Song, J.K.2    Kim, D.S.3
  • 101
    • 77957852320 scopus 로고    scopus 로고
    • Elevated brain natriuretic peptide predicts mortality in interstitial lung disease
    • Corte TJ, Wort SJ, Gatzoulis MA, et al. Elevated brain natriuretic peptide predicts mortality in interstitial lung disease. Eur Respir J 2010; 36: 819-825.
    • (2010) Eur Respir J , vol.36 , pp. 819-825
    • Corte, T.J.1    Wort, S.J.2    Gatzoulis, M.A.3
  • 102
    • 33644828168 scopus 로고    scopus 로고
    • Prognostic value of circulating KL-6 in idiopathic pulmonary fibrosis
    • Yokoyama A, Kondo K, Nakajima M, et al. Prognostic value of circulating KL-6 in idiopathic pulmonary fibrosis. Respirology 2006; 11: 164-168.
    • (2006) Respirology , vol.11 , pp. 164-168
    • Yokoyama, A.1    Kondo, K.2    Nakajima, M.3
  • 103
    • 0036196542 scopus 로고    scopus 로고
    • Serum surfactant proteins-A and -D as biomarkers in idiopathic pulmonary fibrosis
    • Greene KE, King TE, Kuroki Y, et al. Serum surfactant proteins-A and -D as biomarkers in idiopathic pulmonary fibrosis. Eur Respir J 2002; 19: 439-446.
    • (2002) Eur Respir J , vol.19 , pp. 439-446
    • Greene, K.E.1    King, T.E.2    Kuroki, Y.3
  • 104
    • 0027418167 scopus 로고
    • Elevated levels of lung surfactant protein A in sera from patients with idiopathic pulmonary fibrosis and pulmonary alveolar proteinosis
    • Kuroki Y, Tsutahara S, Shijubo N, et al. Elevated levels of lung surfactant protein A in sera from patients with idiopathic pulmonary fibrosis and pulmonary alveolar proteinosis. Am Rev Respir Dis 1993; 147: 723-729.
    • (1993) Am Rev Respir Dis , vol.147 , pp. 723-729
    • Kuroki, Y.1    Tsutahara, S.2    Shijubo, N.3
  • 105
    • 0037260159 scopus 로고    scopus 로고
    • High serum concentrations of surfactant protein A in usual interstitial pneumonia compared with non-specific interstitial pneumonia
    • Ishii H, Mukae H, Kadota J, et al. High serum concentrations of surfactant protein A in usual interstitial pneumonia compared with non-specific interstitial pneumonia. Thorax 2003; 58: 52-57.
    • (2003) Thorax , vol.58 , pp. 52-57
    • Ishii, H.1    Mukae, H.2    Kadota, J.3
  • 106
    • 0037251554 scopus 로고    scopus 로고
    • Prognostic value of surfactant proteins A and D in patients with acute lung injury
    • Cheng IW, Ware LB, Greene KE, et al. Prognostic value of surfactant proteins A and D in patients with acute lung injury. Crit Care Med 2003; 31: 20-27.
    • (2003) Crit Care Med , vol.31 , pp. 20-27
    • Cheng, I.W.1    Ware, L.B.2    Greene, K.E.3
  • 107
    • 63849228099 scopus 로고    scopus 로고
    • Serum surfactant protein-A is a strong predictor of early mortality in idiopathic pulmonary fibrosis
    • Kinder BW, Brown KK, McCormack FX, et al. Serum surfactant protein-A is a strong predictor of early mortality in idiopathic pulmonary fibrosis. Chest 2009; 135: 1557-1563.
    • (2009) Chest , vol.135 , pp. 1557-1563
    • Kinder, B.W.1    Brown, K.K.2    McCormack, F.X.3
  • 108
    • 58849094483 scopus 로고    scopus 로고
    • MMP expression and abnormal lung permeability are important determinants of outcome in IPF
    • McKeown S, Richter AG, O'Kane C, et al. MMP expression and abnormal lung permeability are important determinants of outcome in IPF. Eur Respir J 2009; 33: 77-84.
    • (2009) Eur Respir J , vol.33 , pp. 77-84
    • McKeown, S.1    Richter, A.G.2    O'Kane, C.3
  • 109
    • 65249160219 scopus 로고    scopus 로고
    • Serum CC-chemokine ligand 18 concentration predicts outcome in idiopathic pulmonary fibrosis
    • Prasse A, Probst C, Bargagli E, et al. Serum CC-chemokine ligand 18 concentration predicts outcome in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2009; 179: 717-723.
    • (2009) Am J Respir Crit Care Med , vol.179 , pp. 717-723
    • Prasse, A.1    Probst, C.2    Bargagli, E.3
  • 110
    • 33645845729 scopus 로고    scopus 로고
    • Exhaled markers of oxidative stress in idiopathic pulmonary fibrosis
    • Psathakis K, Mermigkis D, Papatheodorou G, et al. Exhaled markers of oxidative stress in idiopathic pulmonary fibrosis. Eur J Clin Invest 2006; 36: 362-367.
    • (2006) Eur J Clin Invest , vol.36 , pp. 362-367
    • Psathakis, K.1    Mermigkis, D.2    Papatheodorou, G.3
  • 111
    • 38349060783 scopus 로고    scopus 로고
    • Baseline BAL neutrophilia predicts early mortality in idiopathic pulmonary fibrosis
    • Kinder BW, Brown KK, Schwarz MI, et al. Baseline BAL neutrophilia predicts early mortality in idiopathic pulmonary fibrosis. Chest 2008; 133: 226-232.
    • (2008) Chest , vol.133 , pp. 226-232
    • Kinder, B.W.1    Brown, K.K.2    Schwarz, M.I.3
  • 112
    • 10744222693 scopus 로고    scopus 로고
    • BAL findings in idiopathic nonspecific interstitial pneumonia and usual interstitial pneumonia
    • Veeraraghavan S, Latsi PI, Wells AU, et al. BAL findings in idiopathic nonspecific interstitial pneumonia and usual interstitial pneumonia. Eur Respir J 2003; 22: 239-24.4.
    • (2003) Eur Respir J , vol.22 , pp. 239-244
    • Veeraraghavan, S.1    Latsi, P.I.2    Wells, A.U.3
  • 113
    • 0027953965 scopus 로고
    • Fibrosing alveolitis in systemic sclerosis. Bronchoalveolar lavage findings in relation to computed tomographic appearance
    • Wells AU, Hansell DM, Rubens MB, et al. Fibrosing alveolitis in systemic sclerosis. Bronchoalveolar lavage findings in relation to computed tomographic appearance. Am J Respir Crit Care Med 1994; 150: 462-468.
    • (1994) Am J Respir Crit Care Med , vol.150 , pp. 462-468
    • Wells, A.U.1    Hansell, D.M.2    Rubens, M.B.3
  • 114
    • 34447520311 scopus 로고    scopus 로고
    • Bronchoalveolar lavage cellular profiles in patients with systemic sclerosis-associated interstitial lung disease are not predictive of disease progression
    • Goh NS, Veeraraghavan S, Desai SR, et al. Bronchoalveolar lavage cellular profiles in patients with systemic sclerosis-associated interstitial lung disease are not predictive of disease progression. Arthritis Rheum 2007; 56: 2005-2012.
    • (2007) Arthritis Rheum , vol.56 , pp. 2005-2012
    • Goh, N.S.1    Veeraraghavan, S.2    Desai, S.R.3
  • 115
    • 79955674250 scopus 로고    scopus 로고
    • Periostin, a matrix protein, is a novel biomarker for idiopathic interstitial pneumonias
    • Okamoto M, Hoshino T, Kitasato Y, et al. Periostin, a matrix protein, is a novel biomarker for idiopathic interstitial pneumonias. Eur Respir J 2011; 37: 1119-1127.
    • (2011) Eur Respir J , vol.37 , pp. 1119-1127
    • Okamoto, M.1    Hoshino, T.2    Kitasato, Y.3
  • 116
    • 77951160564 scopus 로고    scopus 로고
    • Pirfenidone in idiopathic pulmonary fibrosis
    • Taniguchi H, Ebina M, Kondoh Y, et al. Pirfenidone in idiopathic pulmonary fibrosis. Eur Respir J 2010; 35: 821-829.
    • (2010) Eur Respir J , vol.35 , pp. 821-829
    • Taniguchi, H.1    Ebina, M.2    Kondoh, Y.3
  • 117
    • 80052591490 scopus 로고    scopus 로고
    • A first step against idiopathic pulmonary fibrosis
    • Crestani B. A first step against idiopathic pulmonary fibrosis. Eur Respir Rev 2011; 20: 130-131.
    • (2011) Eur Respir Rev , vol.20 , pp. 130-131
    • Crestani, B.1
  • 118
    • 80052536198 scopus 로고    scopus 로고
    • Emerging potential treatments: New hope for idiopathic pulmonary fibrosis patients?
    • Costabel U. Emerging potential treatments: new hope for idiopathic pulmonary fibrosis patients? Eur Respir Rev 2011; 20: 201-207.
    • (2011) Eur Respir Rev , vol.20 , pp. 201-207
    • Costabel, U.1
  • 119
    • 80052533421 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: Present understanding and future options
    • du Bois RM. Idiopathic pulmonary fibrosis: present understanding and future options. Eur Respir Rev 2011; 20: 132-133.
    • (2011) Eur Respir Rev , vol.20 , pp. 132-133
    • du Bois, R.M.1
  • 120
    • 38849178850 scopus 로고    scopus 로고
    • Idiopathic pulmonary fibrosis: Multiple causes and multiple mechanisms?
    • Maher TM, Wells AU, Laurent GJ. Idiopathic pulmonary fibrosis: multiple causes and multiple mechanisms? Eur Respir J 2007; 30: 835-839.
    • (2007) Eur Respir J , vol.30 , pp. 835-839
    • Maher, T.M.1    Wells, A.U.2    Laurent, G.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.