T cells lacking immunoproteasome subunits MECL-1 and LMP7 hyperproliferate in response to polyclonal mitogens

Journal of Immunology

Volumn 176, Issue 7, 2006, Pages 4075-4082

  Caudill, Christy M ^a   Jayarapu, Krupakar ^a   Elenich, Laura ^a,b   Monaco, John J ^a   Colbert, Robert A ^a   Griffin, Thomas A ^a,c  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b PROCTER AND GAMBLE PHARMACEUTICALS   (United States)

^c CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; IMMUNOPROTEASOME; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MITOGENIC AGENT; PROTEASOME; PROTEIN LMP10; PROTEIN LMP2; PROTEIN LMP7; PROTEIN MECL 1; UNCLASSIFIED DRUG; CYSTEINE PROTEINASE; HLA ANTIGEN CLASS 1; LMP7 PROTEIN; MULTIENZYME COMPLEX; PROTEIN SUBUNIT; PSMB10 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ANTIGEN PRESENTATION; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL FUNCTION; ENZYME SUBUNIT; IMMUNE RESPONSE; IN VITRO STUDY; KNOCKOUT MOUSE; LYMPHOCYTE PROLIFERATION; MEMORY T LYMPHOCYTE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEGRADATION; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION; ANIMAL; CELL CULTURE; CELL PROLIFERATION; CYTOLOGY; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; INNATE IMMUNITY; LYMPHOCYTE ACTIVATION; METABOLISM; MIXED LYMPHOCYTE CULTURE; MOUSE MUTANT; SPLEEN;

ANIMALS; CELL PROLIFERATION; CELLS, CULTURED; CYSTEINE ENDOPEPTIDASES; GENE EXPRESSION REGULATION; HISTOCOMPATIBILITY ANTIGENS CLASS I; IMMUNITY, NATURAL; IMMUNOLOGIC MEMORY; LYMPHOCYTE ACTIVATION; LYMPHOCYTE CULTURE TEST, MIXED; MICE; MICE, KNOCKOUT; MITOGENS; MULTIENZYME COMPLEXES; PHENOTYPE; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN SUBUNITS; SPLEEN; T-LYMPHOCYTES;

EID: 33646053214     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.176.7.4075     Document Type: Article

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