IL-10-induced TNF-alpha mRNA destabilization is mediated via IL-10 suppression of p38 MAP kinase activation and inhibition of HuR expression

FASEB Journal

Volumn 20, Issue 12, 2006, Pages

  Rajasingh, Johnson ^a   Bord, Evelyn ^a   Luedemann, Corinne ^a   Asai, Jun ^a   Hamada, Hiromichi ^a   Thorne, Tina ^a   Qin, Gangjian ^a   Goukassian, David ^a   Zhu, Yan ^a   Losordo, Douglas W ^a   Kishore, Raj ^a,b  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b ST ELIZABETH'S MEDICAL CENTER   (United States)

Author keywords

AU rich elements; mRNA stability

Indexed keywords

CHLORAMPHENICOL ACETYLTRANSFERASE; HUR PROTEIN; INTERLEUKIN 10; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; TUMOR NECROSIS FACTOR ALPHA; CYTOKINE; ELAV-LIKE PROTEIN 1; MEMBRANE ANTIGEN; RNA BINDING PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY DISEASE; ARTICLE; BLOOD VESSEL INJURY; CAROTID ARTERY; CELL INFILTRATION; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; HYPERPLASIA; INFLAMMATION; INFLAMMATORY CELL; MACROPHAGE; MALE; MONOCYTE; MONONUCLEAR PHAGOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROCESSING; VASCULAR DISEASE; VASCULAR SURGERY; VEIN GRAFT DISEASE; ANIMAL; CAROTID ARTERY INJURY; CELL LINE; DOWN REGULATION; DRUG ANTAGONISM; DRUG EFFECT; ENZYME ACTIVATION; GENETIC TRANSFECTION; GENETICS; RNA PROCESSING; RNA STABILITY;

ANIMALS; ANTIGENS, SURFACE; CAROTID ARTERY INJURIES; CELL LINE; CYTOKINES; DOWN-REGULATION; ENZYME ACTIVATION; HUMANS; INTERLEUKIN-10; MICE; MONOCYTES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA STABILITY; RNA, MESSENGER; RNA-BINDING PROTEINS; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33845654723     PISSN: 08926638     EISSN: None     Source Type: Journal    
DOI: 10.1096/fj.06-6084fje     Document Type: Article

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