Cysteines control the N- and C-linker-dependent gating of KCNH1 potassium channels

Biochimica et Biophysica Acta - Biomembranes

Volumn 1818, Issue 5, 2012, Pages 1187-1195

  Sahoo, Nirakar ^a   Schönherr, Roland ^a   Hoshi, Toshinori ^b   Heinemann, Stefan H ^a  

^a JENA UNIVERSITY HOSPITAL   (Germany)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Ether go go; Gating; Oxidation; Potassium channel; Reactive oxygen species; Sulfhydryl modification

Indexed keywords

CYCLIC NUCLEOTIDE GATED CHANNEL; CYSTEINE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL; VOLTAGE GATED POTASSIUM CHANNEL KCNH1;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CELL STRAIN HEK293; CHANNEL GATING; CONTROLLED STUDY; INTRACELLULAR SIGNALING; NONHUMAN; OOCYTE; OXIDATION KINETICS; POROSITY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CROSS LINKING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MODIFICATION; RESIDUE ANALYSIS; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION; XENOPUS LAEVIS;

ANIMALS; CYSTEINE; ETHER-A-GO-GO POTASSIUM CHANNELS; HEK293 CELLS; HUMANS; ION CHANNEL GATING; MUTAGENESIS, SITE-DIRECTED; OXIDATION-REDUCTION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; XENOPUS LAEVIS;

EID: 84857722526     PISSN: 00052736     EISSN: 18792642     Source Type: Journal    
DOI: 10.1016/j.bbamem.2012.01.021     Document Type: Article

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