Current inhibition of human EAG1 potassium channels by the Ca2+ binding protein S100B

FEBS Letters

Volumn 584, Issue 18, 2010, Pages 3896-3900

  Sahoo, Nirakar ^a   Tröger, Jessica ^a,b   Heinemann, Stefan H ^a   Schönherr, Roland ^a  

^a FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Ca2+ binding; Ca2+ regulation; Calmodulin; Melanoma; Potassium channel; Xenopus oocyte

Indexed keywords

CALCIUM ION; POTASSIUM CHANNEL HERG; PROTEIN S100B; CALCIUM; KCNH1 PROTEIN, HUMAN; NERVE GROWTH FACTOR; PROTEIN S 100; S100B PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; BINDING SITE; CONTROLLED STUDY; ELECTROPHYSIOLOGY; EXPRESSION VECTOR; FLUORESCENCE CORRELATION SPECTROSCOPY; INHIBITION KINETICS; MOLECULAR CLONING; NONHUMAN; OOCYTE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PURIFICATION; XENOPUS LAEVIS; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL CULTURE; FLUORESCENCE MICROSCOPY; HUMAN; METABOLISM; XENOPUS;

ANIMALS; BINDING SITES; CALCIUM; CELLS, CULTURED; ETHER-A-GO-GO POTASSIUM CHANNELS; HUMANS; MICROSCOPY, FLUORESCENCE; NERVE GROWTH FACTORS; OOCYTES; S100 PROTEINS; XENOPUS; S100 CALCIUM BINDING PROTEIN BETA SUBUNIT;

EID: 77956909580     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2010.07.063     Document Type: Article

References (32)

1. Ludwig J., Terlau H., Wunder F., Brüggemann A., Pardo L.A., Marquardt A., Stühmer W., Pongs O. Functional expression of a rat homologue of the voltage gated ether à go-go potassium channel reveals differences in selectivity and activation kinetics between the Drosophila channel and its mammalian counterpart. EMBO J. 1994, 13:4451-4458.
2. Meyer R., Heinemann S.H. Characterization of an eag-like potassium channel in human neuroblastoma cells. J. Physiol. 1998, 508:49-56.
3. Meyer R., Schönherr R., Gavrilova-Ruch O., Wohlrab W., Heinemann S.H. Identification of ether à go-go and calcium-activated potassium channels in human melanoma cells. J. Membr. Biol. 1999, 171:107-115.
4. Mello de Queiroz F., Suarez-Kurtz G., Stühmer W., Pardo L.A. Ether à go-go potassium channel expression in soft tissue sarcoma patients. Mol. Cancer 2006, 5:42.
5. + channels in regulating tumor cell proliferation and apoptosis. Pflüg. Arch. 2004, 448:274-286.
6. Pardo L.A., Contreras-Jurado C., Zientkowska M., Alves F., Stühmer W. Role of voltage-gated potassium channels in cancer. J. Membr. Biol. 2005, 205:115-124.
7. Stansfeld C.E., Röper J., Ludwig J., Weseloh R.M., Marsh S.J., Brown D.A., Pongs O. Elevation of intracellular calcium by muscarinic receptor activation induces block of voltage-activated rat ether-à-go-go channels in a stably transfected cell line. Proc. Natl. Acad. Sci. USA 1996, 93:9910-9914.
8. 2+/calmodulin. EMBO J. 2000, 19:3263-3271.
9. 2+/calmodulin binding to the cytosolic N- and C-termini. FEBS J. 2006, 273:1074-1086.
10. Gonçalves J.T., Stühmer W. Calmodulin interaction with hEAG1 visualized by FRET microscopy of human ether à go-go potassium channels. PLoS One 2010, 5:e10873.
11. Santella L. The role of calcium in the cell cycle: facts and hypotheses. Biochem. Biophys. Res. Commun. 1998, 244:317-324.
12. Schafer B.W., Heizmann C.W. The S-100 family of EF-hand calcium-binding proteins: functions and pathology. Trends Biochem. Sci. 1996, 2:134-140.
13. Donato R. Functional roles of S100 proteins, calcium-binding proteins of the EF-hand type. Biochim. Biophys. Acta 1999, 1450:191-231.
14. Marenholz I., Heizmann C.W., Fritz G. S100 proteins in mouse and man: from evolution to function and pathology (including an update of the nomenclature). Biochem. Biophys. Res. Commun. 2004, 322:1111-1122.
15. Zimmer D.B., Wright S.P., Weber D.J. Molecular mechanisms of S100-target protein interactions. Microsc. Res. Tech. 2003, 60:552-559.
16. Donato R. Intracellular and extracellular roles of S100 proteins. Microsc. Res. Tech. 2003, 60:540-551.
17. McClintock K.A., Shaw G.S. A logical sequence search for S100B target proteins. Protein Sci. 2000, 9:2043-2046.
18. Donato R., Sorci G., Riuzzi F., Arcuri C., Bianchi R., Brozzi F., Tubaro C., Giambanco I. S100B's double life: intracellular regulator and extracellular signal. Biochim. Biophys. Acta 2009, 1793:1008-1022.
19. 2+-binding protein S100B: role in D2 receptor function. Mol. Pharm. 2008, 74:317-319.
20. Huttunen H.J., Kuja-Panula J., Sorci G., Agneletti A.L., Donato R., Rauvala H. Coregulation of neurite outgrowth and cell survival by amphoterin and S100 proteins through receptor for advanced glycation end products (RAGE) activation. J. Biol. Chem. 2000, 275:40096-40105.
21. Molina R., Navarro J., Filella X., Castel T., Ballesta A.M. S-100 protein serum levels in patients with benign and malignant diseases: false positive results related to liver and renal function. Tumor Biol. 2002, 23:39-44.
22. Schoenmakers T.J., Visser G.J., Flik G., Theuvenet A.P. CHELATOR: an improved method for computing metal ion concentrations in physiological solutions. Biotechniques 1992, 12:870-879.
23. Rhoads A.R., Friedberg F. Sequence motifs for calmodulin recognition. FASEB J. 1997, 11:331-340.
24. Baudier J., Mochly-Rosen D., Newton A., Lee S.H., Koshland D.E., Cole R.D. Comparison of S100b protein with calmodulin: interactions with melittin and microtubule-associated tau proteins and inhibition of phosphorylation of tau proteins by protein kinase C. Biochemistry 1987, 26:2886-2893.
25. Ivanenkov V.V., Jamieson G.A., Gruenstein E., Dimlich R.V. Characterization of S-100b binding epitopes. Identification of a novel target, the actin capping protein, CapZ. J. Biol. Chem. 1995, 270:14651-14658.
26. Gustina A.S., Trudeau M.C. A recombinant N-terminal domain fully restores deactivation gating in N-truncated and longQT syndrome mutant hERG potassium channels. Proc. Natl. Acad. Sci. USA 2009, 106:13082-13087.
27. Kligman D., Hilt D.C. The S100 protein family. Trends Biochem. Sci. 1988, 11:437-443.
28. Occhiodoro T., Bernheim L., Liu J.H., Bijlenga P., Sinnreich M., Bader C.R., Fischer-Lougheed J. Cloning of a human ether-a-go-go potassium channel expressed in myoblasts at the onset of fusion. FEBS Lett. 1998, 434:177-182.
29. + current, Ih-eag, contributes to the hyperpolarization of human fusion-competent myoblasts. J. Physiol. 1998, 512:317-323.
30. Tubaro C., Arcuri C., Giambanco I., Donato R. S100B protein in myoblasts modulates myogenic differentiation via NF-kappaB-dependent inhibition of MyoD expression. J. Cell. Physiol. 2010, 223:270-282.
31. Adami C., Sorci G., Blasi E., Agneletti A.L., Bistoni F., Donato R. S100B expression in and effects on microglia. Glia 2001, 33:131-142.
32. Schlagenhauff B., Schittek B., Ellwanger U., Stroebel W., Blum A., Schwarz M. Significance of serum protein S100 levels in screening for melanoma metastasis: does protein S100 enable early detection of melanoma recurrence?. Melanoma Res. 2000, 10:451-459.