The value of acute toxicity testing of pharmaceuticals for estimation of human response

Regulatory Toxicology and Pharmacology

Volumn 62, Issue 3, 2012, Pages 412-418

  Lovšin Barle, Ester ^a   Looser, Roland ^b   Černe, Manica ^a   Bechter, Rudolf ^b  

^a Lek dd   (Slovenia)

^b NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Acute toxicity; Classification; Labeling; Pharmaceuticals

Indexed keywords

ACETYLSALICYLIC ACID; INDOMETACIN; WARFARIN;

ACUTE TOXICITY; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DIAGNOSTIC VALUE; DISEASE CLASSIFICATION; DOG; HUMAN; HUMAN EXPERIMENT; LD 50; LINEAR REGRESSION ANALYSIS; MOUSE; NONHUMAN; NORMAL HUMAN; PRIORITY JOURNAL; RABBIT; RAT; RISK ASSESSMENT; TOXICITY TESTING; TOXICOLOGY; VALIDATION PROCESS; VALIDITY;

ADMINISTRATION, ORAL; ANIMALS; DOGS; DRUG TOXICITY; HUMANS; LETHAL DOSE 50; MICE; PHARMACEUTICAL PREPARATIONS; RABBITS; RATS; SPECIES SPECIFICITY; TOXICITY TESTS, ACUTE;

ANIMALIA; CANIS FAMILIARIS; RATTUS;

EID: 84857594514     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2012.01.005     Document Type: Article

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