Acute toxicity testing of chemicals - Opportunities to avoid redundant testing and use alternative approaches

Critical Reviews in Toxicology

Volumn 40, Issue 1, 2010, Pages 50-83

  Creton, Stuart ^a   Dewhurst, Ian C ^b   Earl, Lesley K ^c   Gehen, Sean C ^d   Guest, Robert L ^e   Hotchkiss, Jon A ^f   Indans, Ian ^b   Woolhiser, Michael R ^f   Billington, Richard ^g  

^a National Centre for the Replacement   (United Kingdom)

^b HEALTH AND SAFETY EXECUTIVE   (United Kingdom)

^c HUNTINGDON LIFE SCIENCES   (United Kingdom)

^d DOW AGROSCIENCES LLC   (United States)

^e Harlan   (Switzerland)

^f DOW CHEMICAL COMPANY   (United States)

^g Dow AgroSciences Ltd   (United Kingdom)

Author keywords

3Rs; Acute toxicity; Animal testing; Irritation; Regulatory; Sensitisation

Indexed keywords

ACEPHATE; ACID; ACID ANHYDRIDE; ACID HALIDE; ALACHLOR; ALDICARB; ALIPHATIC AMINE; AMITRAZ; ATRAZINE; BASE; BENOMYL; BROMOXYNIL; CAPTAN; CHLORPYRIFOS; CIPERMETHRIN; CYFLUTHRIN; DAMINOZIDE; DELTAMETHRIN; DINOCAP; DIQUAT; DIURON; INDUSTRIAL CHEMICAL; PESTICIDE;

ASSAY; CLINICAL PROTOCOL; CORROSION; EYE IRRITATION; HAZARD; HAZARD ASSESSMENT; IN VITRO STUDY; IN VIVO STUDY; INFORMATION; INHALATION; LD 50; LYMPH NODE; METHODOLOGY; NONHUMAN; PRACTICE GUIDELINE; REVIEW; RISK ASSESSMENT; SENSITIZATION; SKIN IRRITATION; SKIN SENSITIZATION; SKIN TEST; TOXICITY TESTING; VALIDATION STUDY;

ACUTE TOXICITY TESTS; ADMINISTRATION, ORAL; ADMINISTRATION, TOPICAL; ANIMAL TESTING ALTERNATIVES; ANIMALS; HUMANS; INHALATION EXPOSURE; INTERNATIONAL COOPERATION; RISK ASSESSMENT; SKIN IRRITANCY TESTS;

ANIMALIA;

EID: 73649130953     PISSN: 10408444     EISSN: 15476898     Source Type: Journal    
DOI: 10.3109/10408440903401511     Document Type: Review

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