The value of acute toxicity studies to support the clinical management of overdose and poisoning: A cross-discipline consensus

Regulatory Toxicology and Pharmacology

Volumn 58, Issue 3, 2010, Pages 354-359

  Chapman, Kathryn ^a   Creton, Stuart ^a   Kupferschmidt, Hugo ^b   Bond, G Randall ^c   Wilks, Martin F ^d   Robinson, Sally ^e  

^a National Centre for the Replacement   (United Kingdom)

^b Schweizerisches Toxikologisches Informationszentrum   (Switzerland)

^c Cincinnati Drug and Poison Information Center   (United States)

^d Swiss Centre for Applied Human Toxicology   (Switzerland)

^e ASTRAZENECA   (United Kingdom)

Author keywords

Acute toxicity; Animal; Chemicals; ICH M3; Overdose; Pharmaceuticals; Poisoning; Preclinical; Safety

Indexed keywords

AGRICULTURAL CHEMICAL; CHEMICAL AGENT; COSMETIC; DOMESTIC CHEMICAL; DRUG; ILLICIT DRUG; INDUSTRIAL CHEMICAL; RECREATIONAL DRUG; VETERINARY DRUG;

ACUTE TOXICITY; ARTICLE; CHEMICAL CLASSIFICATION; CHEMICAL INDUSTRY; CHEMICAL LABELING; CLASSIFICATION; DRUG DEVELOPMENT; DRUG INDUSTRY; DRUG INTOXICATION; DRUG OVERDOSE; FOOD POISONING; GOVERNMENT; HUMAN; LD 50; MUSHROOM; NONHUMAN; PATIENT CARE; PLANT; POISON CENTER; POISONOUS ANIMAL; PRIORITY JOURNAL; RISK ASSESSMENT; WORKSHOP; ANIMAL; CLINICAL TRIAL (TOPIC); CONFERENCE PAPER; CONSENSUS; CONSENSUS DEVELOPMENT; DRUG LABELING; INTOXICATION; PRACTICE GUIDELINE; TOXICITY TESTING;

ANIMALIA;

ACUTE TOXICITY TESTS; ANIMALS; CHEMICAL INDUSTRY; CLINICAL TRIALS AS TOPIC; CONSENSUS; DRUG INDUSTRY; DRUG LABELING; GUIDELINES AS TOPIC; HUMANS; OVERDOSE; PHARMACEUTICAL PREPARATIONS; POISON CONTROL CENTERS; POISONING; RISK ASSESSMENT;

EID: 79959495804     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2010.07.003     Document Type: Article

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