-
1
-
-
84971581087
-
Chemotherapy in non-small cell lung cancer: A meta-analysis using updated data on individual patients from 52 randomised clinical trials. Non-small Cell Lung Cancer Collaborative Group
-
Anon,. Chemotherapy in non-small cell lung cancer: a meta-analysis using updated data on individual patients from 52 randomised clinical trials. Non-small Cell Lung Cancer Collaborative Group. BMJ 1995; 311: 899-909.
-
(1995)
BMJ
, vol.311
, pp. 899-909
-
-
-
2
-
-
1342268525
-
American Society of Clinical Oncology treatment of unresectable non-small-cell lung cancer guideline: Update 2003
-
Pfister DG, Johnson DH, Azzoli CG, Sause W, Smith TJ, Baker S, Jr, Olak J, Stover D, Strawn JR, Turrisi AT, Somerfield MR,. American Society of Clinical Oncology treatment of unresectable non-small-cell lung cancer guideline: update 2003. J Clin Oncol 2004; 22: 330-53.
-
(2004)
J Clin Oncol
, vol.22
, pp. 330-353
-
-
Pfister, D.G.1
Johnson, D.H.2
Azzoli, C.G.3
Sause, W.4
Smith, T.J.5
Baker, Jr.S.6
Olak, J.7
Stover, D.8
Strawn, J.R.9
Turrisi, A.T.10
Somerfield, M.R.11
-
3
-
-
23844445571
-
Thymidylate synthase structure, function and implication in drug discovery
-
Costi MP, Ferrari S, Venturelli A, Calo S, Tondi D, Barlocco D,. Thymidylate synthase structure, function and implication in drug discovery. Curr Med Chem 2005; 12: 2241-58.
-
(2005)
Curr Med Chem
, vol.12
, pp. 2241-2258
-
-
Costi, M.P.1
Ferrari, S.2
Venturelli, A.3
Calo, S.4
Tondi, D.5
Barlocco, D.6
-
5
-
-
0346103806
-
Altered gene expression of folate enzymes in adjacent mucosa is associated with outcome of colorectal cancer patients
-
Odin E, Wettergren Y, Nilsson S, Willen R, Carlsson G, Spears CP, Larsson L, Gustavsson B,. Altered gene expression of folate enzymes in adjacent mucosa is associated with outcome of colorectal cancer patients. Clin Cancer Res 2003; 9: 6012-9.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 6012-6019
-
-
Odin, E.1
Wettergren, Y.2
Nilsson, S.3
Willen, R.4
Carlsson, G.5
Spears, C.P.6
Larsson, L.7
Gustavsson, B.8
-
6
-
-
19244381642
-
Thymidylate synthase levels as a therapeutic and prognostic predictor in breast cancer
-
Nishimura R, Nagao K, Miyayama H, Matsuda M, Baba K, Matsuoka Y, Yamashita H, Fukuda M, Higuchi A, Satoh A, Mizumoto T, Hamamoto R,. Thymidylate synthase levels as a therapeutic and prognostic predictor in breast cancer. Anticancer Res 1999; 19: 5621-6.
-
(1999)
Anticancer Res
, vol.19
, pp. 5621-5626
-
-
Nishimura, R.1
Nagao, K.2
Miyayama, H.3
Matsuda, M.4
Baba, K.5
Matsuoka, Y.6
Yamashita, H.7
Fukuda, M.8
Higuchi, A.9
Satoh, A.10
Mizumoto, T.11
Hamamoto, R.12
-
7
-
-
0033395108
-
Prognostic value of p53, glutathione S-transferase pi, and thymidylate synthase for neoadjuvant cisplatin-based chemotherapy in head and neck cancer
-
Shiga H, Heath EI, Rasmussen AA, Trock B, Johnston PG, Forastiere AA, Langmacher M, Baylor A, Lee M, Cullen KJ,. Prognostic value of p53, glutathione S-transferase pi, and thymidylate synthase for neoadjuvant cisplatin-based chemotherapy in head and neck cancer. Clin Cancer Res 1999; 5: 4097-104.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 4097-4104
-
-
Shiga, H.1
Heath, E.I.2
Rasmussen, A.A.3
Trock, B.4
Johnston, P.G.5
Forastiere, A.A.6
Langmacher, M.7
Baylor, A.8
Lee, M.9
Cullen, K.J.10
-
8
-
-
0036183722
-
Implication of thymidylate synthase in the outcome of patients with invasive ductal carcinoma of the pancreas and efficacy of adjuvant chemotherapy using 5-fluorouracil or its derivatives
-
Takamura M, Nio Y, Yamasawa K, Dong M, Yamaguchi K, Itakura M,. Implication of thymidylate synthase in the outcome of patients with invasive ductal carcinoma of the pancreas and efficacy of adjuvant chemotherapy using 5-fluorouracil or its derivatives. Anticancer Drugs 2002; 13: 75-85.
-
(2002)
Anticancer Drugs
, vol.13
, pp. 75-85
-
-
Takamura, M.1
Nio, Y.2
Yamasawa, K.3
Dong, M.4
Yamaguchi, K.5
Itakura, M.6
-
9
-
-
3042756923
-
Thymidylate synthase and dihydropyrimidine dehydrogenase mRNA levels in tumor tissues and the efficacy of 5-fluorouracil in patients with non-small-cell lung cancer
-
Shintani Y, Ohta M, Hirabayashi H, Tanaka H, Iuchi K, Nakagawa K, Maeda H, Kido T, Miyoshi S, Matsuda H,. Thymidylate synthase and dihydropyrimidine dehydrogenase mRNA levels in tumor tissues and the efficacy of 5-fluorouracil in patients with non-small-cell lung cancer. Lung Cancer 2004; 45: 189-96.
-
(2004)
Lung Cancer
, vol.45
, pp. 189-196
-
-
Shintani, Y.1
Ohta, M.2
Hirabayashi, H.3
Tanaka, H.4
Iuchi, K.5
Nakagawa, K.6
Maeda, H.7
Kido, T.8
Miyoshi, S.9
Matsuda, H.10
-
10
-
-
33749587054
-
Squamous cell carcinoma of the lung compared with other histotypes shows higher messenger RNA and protein levels for thymidylate synthase
-
Ceppi P, Volante M, Saviozzi S, Rapa I, Novello S, Cambieri A, Lo Iacono M, Cappia S, Papotti M, Scagliotti GV,. Squamous cell carcinoma of the lung compared with other histotypes shows higher messenger RNA and protein levels for thymidylate synthase. Cancer 2006; 107: 1589-96.
-
(2006)
Cancer
, vol.107
, pp. 1589-1596
-
-
Ceppi, P.1
Volante, M.2
Saviozzi, S.3
Rapa, I.4
Novello, S.5
Cambieri, A.6
Lo Iacono, M.7
Cappia, S.8
Papotti, M.9
Scagliotti, G.V.10
-
11
-
-
1842685083
-
Thymidylate synthase as an oncogene: A novel role for an essential DNA synthesis enzyme
-
Rahman L, Voeller D, Rahman M, Lipkowitz S, Allegra C, Barrett JC, Kaye FJ, Zajac-Kaye M,. Thymidylate synthase as an oncogene: a novel role for an essential DNA synthesis enzyme. Cancer Cell 2004; 5: 341-51.
-
(2004)
Cancer Cell
, vol.5
, pp. 341-351
-
-
Rahman, L.1
Voeller, D.2
Rahman, M.3
Lipkowitz, S.4
Allegra, C.5
Barrett, J.C.6
Kaye, F.J.7
Zajac-Kaye, M.8
-
12
-
-
0035177724
-
Pemetrexed disodium (Eli Lilly)
-
Norman P,. Pemetrexed disodium (Eli Lilly). Curr Opin Investig Drugs 2001; 2: 1611-22.
-
(2001)
Curr Opin Investig Drugs
, vol.2
, pp. 1611-1622
-
-
Norman, P.1
-
13
-
-
71849118033
-
Significance of thymidylate synthase for resistance to pemetrexed in lung cancer
-
Ozasa H, Oguri T, Uemura T, Miyazaki M, Maeno K, Sato S, Ueda R,. Significance of thymidylate synthase for resistance to pemetrexed in lung cancer. Cancer Sci 2010; 101: 161-6.
-
(2010)
Cancer Sci
, vol.101
, pp. 161-166
-
-
Ozasa, H.1
Oguri, T.2
Uemura, T.3
Miyazaki, M.4
Maeno, K.5
Sato, S.6
Ueda, R.7
-
14
-
-
0041695633
-
Induction of resistance to the multitargeted antifolate Pemetrexed (ALIMTA) in WiDr human colon cancer cells is associated with thymidylate synthase overexpression
-
Sigmond J, Backus HH, Wouters D, Temmink OH, Jansen G, Peters GJ,. Induction of resistance to the multitargeted antifolate Pemetrexed (ALIMTA) in WiDr human colon cancer cells is associated with thymidylate synthase overexpression. Biochem Pharmacol 2003; 66: 431-8.
-
(2003)
Biochem Pharmacol
, vol.66
, pp. 431-438
-
-
Sigmond, J.1
Backus, H.H.2
Wouters, D.3
Temmink, O.H.4
Jansen, G.5
Peters, G.J.6
-
15
-
-
77955092334
-
Genetic determinants of pemetrexed responsiveness and nonresponsiveness in non-small cell lung cancer cells
-
Wu MF, Hsiao YM, Huang CF, Huang YH, Yang WJ, Chan HW, Chang JT, Ko JL,. Genetic determinants of pemetrexed responsiveness and nonresponsiveness in non-small cell lung cancer cells. J Thorac Oncol 2010; 5: 1143-51.
-
(2010)
J Thorac Oncol
, vol.5
, pp. 1143-1151
-
-
Wu, M.F.1
Hsiao, Y.M.2
Huang, C.F.3
Huang, Y.H.4
Yang, W.J.5
Chan, H.W.6
Chang, J.T.7
Ko, J.L.8
-
16
-
-
73349084270
-
Differential thymidylate synthase expression in different variants of large-cell carcinoma of the lung
-
Monica V, Scagliotti GV, Ceppi P, Righi L, Cambieri A, Lo Iacono M, Saviozzi S, Volante M, Novello S, Papotti M,. Differential thymidylate synthase expression in different variants of large-cell carcinoma of the lung. Clin Cancer Res 2009; 15: 7547-52.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 7547-7552
-
-
Monica, V.1
Scagliotti, G.V.2
Ceppi, P.3
Righi, L.4
Cambieri, A.5
Lo Iacono, M.6
Saviozzi, S.7
Volante, M.8
Novello, S.9
Papotti, M.10
-
17
-
-
39749121476
-
Thymidylate synthase expression in gastroenteropancreatic and pulmonary neuroendocrine tumors
-
Ceppi P, Volante M, Ferrero A, Righi L, Rapa I, Rosas R, Berruti A, Dogliotti L, Scagliotti GV, Papotti M,. Thymidylate synthase expression in gastroenteropancreatic and pulmonary neuroendocrine tumors. Clin Cancer Res 2008; 14: 1059-64.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 1059-1064
-
-
Ceppi, P.1
Volante, M.2
Ferrero, A.3
Righi, L.4
Rapa, I.5
Rosas, R.6
Berruti, A.7
Dogliotti, L.8
Scagliotti, G.V.9
Papotti, M.10
-
18
-
-
77955053922
-
Identification of thymidylate synthase as a potential therapeutic target for lung cancer
-
Takezawa K, Okamoto I, Tsukioka S, Uchida J, Kiniwa M, Fukuoka M, Nakagawa K,. Identification of thymidylate synthase as a potential therapeutic target for lung cancer. Br J Cancer 2010; 103: 354-61.
-
(2010)
Br J Cancer
, vol.103
, pp. 354-361
-
-
Takezawa, K.1
Okamoto, I.2
Tsukioka, S.3
Uchida, J.4
Kiniwa, M.5
Fukuoka, M.6
Nakagawa, K.7
-
19
-
-
77949911427
-
Biological prognostic and predictive factors in lung cancer
-
Rossi A, Galetta D, Gridelli C,. Biological prognostic and predictive factors in lung cancer. Oncology 2009; 77 (Suppl 1): 90-6.
-
(2009)
Oncology
, vol.77
, Issue.SUPPL. 1
, pp. 90-96
-
-
Rossi, A.1
Galetta, D.2
Gridelli, C.3
-
20
-
-
0037842139
-
Phase II study of pemetrexed with and without folic acid and vitamin B12 as front-line therapy in malignant pleural mesothelioma
-
Scagliotti GV, Shin DM, Kindler HL, Vasconcelles MJ, Keppler U, Manegold C, Burris H, Gatzemeier U, Blatter J, Symanowski JT, Rusthoven JJ,. Phase II study of pemetrexed with and without folic acid and vitamin B12 as front-line therapy in malignant pleural mesothelioma. J Clin Oncol 2003; 21: 1556-61.
-
(2003)
J Clin Oncol
, vol.21
, pp. 1556-1561
-
-
Scagliotti, G.V.1
Shin, D.M.2
Kindler, H.L.3
Vasconcelles, M.J.4
Keppler, U.5
Manegold, C.6
Burris, H.7
Gatzemeier, U.8
Blatter, J.9
Symanowski, J.T.10
Rusthoven, J.J.11
-
21
-
-
70350435454
-
Phase III study of pemetrexed plus carboplatin compared with etoposide plus carboplatin in chemotherapy-naive patients with extensive-stage small-cell lung cancer
-
Socinski MA, Smit EF, Lorigan P, Konduri K, Reck M, Szczesna A, Blakely J, Serwatowski P, Karaseva NA, Ciuleanu T, Jassem J, Dediu M, et al. Phase III study of pemetrexed plus carboplatin compared with etoposide plus carboplatin in chemotherapy-naive patients with extensive-stage small-cell lung cancer. J Clin Oncol 2009; 27: 4787-92.
-
(2009)
J Clin Oncol
, vol.27
, pp. 4787-4792
-
-
Socinski, M.A.1
Smit, E.F.2
Lorigan, P.3
Konduri, K.4
Reck, M.5
Szczesna, A.6
Blakely, J.7
Serwatowski, P.8
Karaseva, N.A.9
Ciuleanu, T.10
Jassem, J.11
Dediu, M.12
-
22
-
-
33847009160
-
SRC-family kinases are activated in non-small cell lung cancer and promote the survival of epidermal growth factor receptor-dependent cell lines
-
Zhang J, Kalyankrishna S, Wislez M, Thilaganathan N, Saigal B, Wei W, Ma L, Wistuba II, Johnson FM, Kurie JM,. SRC-family kinases are activated in non-small cell lung cancer and promote the survival of epidermal growth factor receptor-dependent cell lines. Am J Pathol 2007; 170: 366-76.
-
(2007)
Am J Pathol
, vol.170
, pp. 366-376
-
-
Zhang, J.1
Kalyankrishna, S.2
Wislez, M.3
Thilaganathan, N.4
Saigal, B.5
Wei, W.6
Ma, L.7
Wistuba, I.I.8
Johnson, F.M.9
Kurie, J.M.10
-
23
-
-
46249085203
-
Src as a potential therapeutic target in non-small-cell lung cancer
-
Giaccone G, Zucali PA,. Src as a potential therapeutic target in non-small-cell lung cancer. Ann Oncol 2008; 19: 1219-23.
-
(2008)
Ann Oncol
, vol.19
, pp. 1219-1223
-
-
Giaccone, G.1
Zucali, P.A.2
-
24
-
-
19944428353
-
Discovery of N-(2-chloro-6-methyl- phenyl)-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2-methylpyrimidin-4- ylamino)thiazole-5-carboxamide (BMS-354825), a dual Src/Abl kinase inhibitor with potent antitumor activity in preclinical assays
-
Lombardo LJ, Lee FY, Chen P, Norris D, Barrish JC, Behnia K, Castaneda S, Cornelius LA, Das J, Doweyko AM, Fairchild C, Hunt JT, et al. Discovery of N-(2-chloro-6-methyl- phenyl)-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2- methylpyrimidin-4- ylamino)thiazole-5-carboxamide (BMS-354825), a dual Src/Abl kinase inhibitor with potent antitumor activity in preclinical assays. J Med Chem 2004; 47: 6658-61.
-
(2004)
J Med Chem
, vol.47
, pp. 6658-6661
-
-
Lombardo, L.J.1
Lee, F.Y.2
Chen, P.3
Norris, D.4
Barrish, J.C.5
Behnia, K.6
Castaneda, S.7
Cornelius, L.A.8
Das, J.9
Doweyko, A.M.10
Fairchild, C.11
Hunt, J.T.12
-
25
-
-
33745243692
-
Dasatinib (BMS-354825) selectively induces apoptosis in lung cancer cells dependent on epidermal growth factor receptor signaling for survival
-
Song L, Morris M, Bagui T, Lee FY, Jove R, Haura EB,. Dasatinib (BMS-354825) selectively induces apoptosis in lung cancer cells dependent on epidermal growth factor receptor signaling for survival. Cancer Res 2006; 66: 5542-8.
-
(2006)
Cancer Res
, vol.66
, pp. 5542-5548
-
-
Song, L.1
Morris, M.2
Bagui, T.3
Lee, F.Y.4
Jove, R.5
Haura, E.B.6
-
26
-
-
78049495513
-
Phase II study of dasatinib in patients with advanced non-small-cell lung cancer
-
Johnson FM, Bekele BN, Feng L, Wistuba I, Tang XM, Tran HT, Erasmus JJ, Hwang LL, Takebe N, Blumenschein GR, Lippman SM, Stewart DJ,. Phase II study of dasatinib in patients with advanced non-small-cell lung cancer. J Clin Oncol 2010; 28: 4609-15.
-
(2010)
J Clin Oncol
, vol.28
, pp. 4609-4615
-
-
Johnson, F.M.1
Bekele, B.N.2
Feng, L.3
Wistuba, I.4
Tang, X.M.5
Tran, H.T.6
Erasmus, J.J.7
Hwang, L.L.8
Takebe, N.9
Blumenschein, G.R.10
Lippman, S.M.11
Stewart, D.J.12
-
27
-
-
70949093847
-
Effects of Src kinase inhibition induced by dasatinib in non-small cell lung cancer cell lines treated with cisplatin
-
Ceppi P, Papotti M, Monica V, Iacono ML, Saviozzi S, Pautasso M, Novello S, Mussino S, Bracco E, Volante M, Scagliotti GV,. Effects of Src kinase inhibition induced by dasatinib in non-small cell lung cancer cell lines treated with cisplatin. Mol Cancer Ther 2009; 8: 3066-74.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 3066-3074
-
-
Ceppi, P.1
Papotti, M.2
Monica, V.3
Iacono, M.L.4
Saviozzi, S.5
Pautasso, M.6
Novello, S.7
Mussino, S.8
Bracco, E.9
Volante, M.10
Scagliotti, G.V.11
-
28
-
-
57349147100
-
Inhibition of Src tyrosine kinase reverts chemoresistance toward 5-fluorouracil in human pancreatic carcinoma cells: An involvement of epidermal growth factor receptor signaling
-
Ischenko I, Camaj P, Seeliger H, Kleespies A, Guba M, De Toni EN, Schwarz B, Graeb C, Eichhorn ME, Jauch KW, Bruns CJ,. Inhibition of Src tyrosine kinase reverts chemoresistance toward 5-fluorouracil in human pancreatic carcinoma cells: an involvement of epidermal growth factor receptor signaling. Oncogene 2008; 27: 7212-22.
-
(2008)
Oncogene
, vol.27
, pp. 7212-7222
-
-
Ischenko, I.1
Camaj, P.2
Seeliger, H.3
Kleespies, A.4
Guba, M.5
De Toni, E.N.6
Schwarz, B.7
Graeb, C.8
Eichhorn, M.E.9
Jauch, K.W.10
Bruns, C.J.11
-
29
-
-
15744373791
-
-
World Health Organization, International Agency for Research on Cancer, International Association for the Study of Lung Cancer, International Academy of Pathology. Lyon: IARC Press.
-
Travis WD, World Health Organization, International Agency for Research on Cancer, International Association for the Study of Lung Cancer, International Academy of Pathology. Pathology and genetics of tumours of the lung, pleura, thymus, and hearted. Lyon: IARC Press, 2004; 9-11.
-
(2004)
Pathology and Genetics of Tumours of the Lung, Pleura, Thymus, and Hearted
, pp. 9-11
-
-
Travis, W.D.1
-
30
-
-
0027518618
-
Proto-oncogene and growth factor/receptor expression in the establishment of primary human non-small cell lung carcinoma cell lines
-
Liu C, Tsao MS,. Proto-oncogene and growth factor/receptor expression in the establishment of primary human non-small cell lung carcinoma cell lines. Am J Path 1993; 142: 413-23.
-
(1993)
Am J Path
, vol.142
, pp. 413-423
-
-
Liu, C.1
Tsao, M.S.2
-
31
-
-
0034889197
-
Drug synergism: Its detection and applications
-
Tallarida RJ,. Drug synergism: its detection and applications. J Pharmacol Exp Ther 2001; 298: 865-72.
-
(2001)
J Pharmacol Exp Ther
, vol.298
, pp. 865-872
-
-
Tallarida, R.J.1
-
32
-
-
0037784223
-
Pp60c-src activation in lung adenocarcinoma
-
Masaki T, Igarashi K, Tokuda M, Yukimasa S, Han F, Jin YJ, Li JQ, Yoneyama H, Uchida N, Fujita J, Yoshiji H, Watanabe S, et al. pp60c-src activation in lung adenocarcinoma. Eur J Cancer 2003; 39: 1447-55.
-
(2003)
Eur J Cancer
, vol.39
, pp. 1447-1455
-
-
Masaki, T.1
Igarashi, K.2
Tokuda, M.3
Yukimasa, S.4
Han, F.5
Jin, Y.J.6
Li, J.Q.7
Yoneyama, H.8
Uchida, N.9
Fujita, J.10
Yoshiji, H.11
Watanabe, S.12
-
33
-
-
65949124261
-
Non-small cell lung cancer exhibits transcript overexpression of genes associated with homologous recombination and DNA replication pathways
-
Saviozzi S, Ceppi P, Novello S, Ghio P, Lo Iacono M, Borasio P, Cambieri A, Volante M, Papotti M, Calogero RA, Scagliotti GV,. Non-small cell lung cancer exhibits transcript overexpression of genes associated with homologous recombination and DNA replication pathways. Cancer Res 2009; 69: 3390-6.
-
(2009)
Cancer Res
, vol.69
, pp. 3390-3396
-
-
Saviozzi, S.1
Ceppi, P.2
Novello, S.3
Ghio, P.4
Lo Iacono, M.5
Borasio, P.6
Cambieri, A.7
Volante, M.8
Papotti, M.9
Calogero, R.A.10
Scagliotti, G.V.11
-
34
-
-
0037080135
-
Activation of Src kinase in primary colorectal carcinoma: An indicator of poor clinical prognosis
-
Allgayer H, Boyd DD, Heiss MM, Abdalla EK, Curley SA, Gallick GE,. Activation of Src kinase in primary colorectal carcinoma: an indicator of poor clinical prognosis. Cancer 2002; 94: 344-51.
-
(2002)
Cancer
, vol.94
, pp. 344-351
-
-
Allgayer, H.1
Boyd, D.D.2
Heiss, M.M.3
Abdalla, E.K.4
Curley, S.A.5
Gallick, G.E.6
-
35
-
-
33751028441
-
Activated c-SRC in ductal carcinoma in situ correlates with high tumour grade, high proliferation and HER2 positivity
-
Wilson GR, Cramer A, Welman A, Knox F, Swindell R, Kawakatsu H, Clarke RB, Dive C, Bundred NJ,. Activated c-SRC in ductal carcinoma in situ correlates with high tumour grade, high proliferation and HER2 positivity. Br J Cancer 2006; 95: 1410-4.
-
(2006)
Br J Cancer
, vol.95
, pp. 1410-1414
-
-
Wilson, G.R.1
Cramer, A.2
Welman, A.3
Knox, F.4
Swindell, R.5
Kawakatsu, H.6
Clarke, R.B.7
Dive, C.8
Bundred, N.J.9
-
36
-
-
34648815009
-
Lung cancer in never smokersâ€"a different disease
-
Sun S, Schiller JH, Gazdar AF,. Lung cancer in never smokers†"a different disease. Nat Rev 2007; 7: 778-90.
-
(2007)
Nat Rev
, vol.7
, pp. 778-790
-
-
Sun, S.1
Schiller, J.H.2
Gazdar, A.F.3
-
37
-
-
4444344330
-
EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib
-
Pao W, Miller V, Zakowski M, Doherty J, Politi K, Sarkaria I, Singh B, Heelan R, Rusch V, Fulton L, Mardis E, Kupfer D, et al. EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib. Proc Natl Acad Sci USA 2004; 101: 13306-11.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 13306-13311
-
-
Pao, W.1
Miller, V.2
Zakowski, M.3
Doherty, J.4
Politi, K.5
Sarkaria, I.6
Singh, B.7
Heelan, R.8
Rusch, V.9
Fulton, L.10
Mardis, E.11
Kupfer, D.12
-
38
-
-
34547638047
-
Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer
-
Soda M, Choi YL, Enomoto M, Takada S, Yamashita Y, Ishikawa S, Fujiwara S, Watanabe H, Kurashina K, Hatanaka H, Bando M, Ohno S, et al. Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer. Nature 2007; 448: 561-6.
-
(2007)
Nature
, vol.448
, pp. 561-566
-
-
Soda, M.1
Choi, Y.L.2
Enomoto, M.3
Takada, S.4
Yamashita, Y.5
Ishikawa, S.6
Fujiwara, S.7
Watanabe, H.8
Kurashina, K.9
Hatanaka, H.10
Bando, M.11
Ohno, S.12
-
39
-
-
33746672599
-
Nicotine induces cell proliferation by beta-arrestin-mediated activation of Src and Rb-Raf-1 pathways
-
Dasgupta P, Rastogi S, Pillai S, Ordonez-Ercan D, Morris M, Haura E, Chellappan S,. Nicotine induces cell proliferation by beta-arrestin-mediated activation of Src and Rb-Raf-1 pathways. J Clin Invest 2006; 116: 2208-17.
-
(2006)
J Clin Invest
, vol.116
, pp. 2208-2217
-
-
Dasgupta, P.1
Rastogi, S.2
Pillai, S.3
Ordonez-Ercan, D.4
Morris, M.5
Haura, E.6
Chellappan, S.7
-
40
-
-
37249080638
-
E2F1 overexpression correlates with thymidylate synthase and survivin gene expressions and tumor proliferation in non small-cell lung cancer
-
Huang CL, Liu D, Nakano J, Yokomise H, Ueno M, Kadota K, Wada H,. E2F1 overexpression correlates with thymidylate synthase and survivin gene expressions and tumor proliferation in non small-cell lung cancer. Clin Cancer Res 2007; 13: 6938-46.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 6938-6946
-
-
Huang, C.L.1
Liu, D.2
Nakano, J.3
Yokomise, H.4
Ueno, M.5
Kadota, K.6
Wada, H.7
-
41
-
-
0032924293
-
V-src induces cisplatin resistance by increasing the repair of cisplatin-DNA interstrand cross-links in human gallbladder adenocarcinoma cells
-
Masumoto N, Nakano S, Fujishima H, Kohno K, Niho Y,. v-src induces cisplatin resistance by increasing the repair of cisplatin-DNA interstrand cross-links in human gallbladder adenocarcinoma cells. Int J Cancer 1999; 80: 731-7.
-
(1999)
Int J Cancer
, vol.80
, pp. 731-737
-
-
Masumoto, N.1
Nakano, S.2
Fujishima, H.3
Kohno, K.4
Niho, Y.5
-
42
-
-
41149096042
-
Molecular mechanisms underlying the synergistic interaction of erlotinib, an epidermal growth factor receptor tyrosine kinase inhibitor, with the multitargeted antifolate pemetrexed in non-small-cell lung cancer cells
-
Giovannetti E, Lemos C, Tekle C, Smid K, Nannizzi S, Rodriguez JA, Ricciardi S, Danesi R, Giaccone G, Peters GJ,. Molecular mechanisms underlying the synergistic interaction of erlotinib, an epidermal growth factor receptor tyrosine kinase inhibitor, with the multitargeted antifolate pemetrexed in non-small-cell lung cancer cells. Mol Pharmacol 2008; 73: 1290-300.
-
(2008)
Mol Pharmacol
, vol.73
, pp. 1290-1300
-
-
Giovannetti, E.1
Lemos, C.2
Tekle, C.3
Smid, K.4
Nannizzi, S.5
Rodriguez, J.A.6
Ricciardi, S.7
Danesi, R.8
Giaccone, G.9
Peters, G.J.10
-
43
-
-
13644254794
-
Molecular mechanisms of drug resistance
-
Longley DB, Johnston PG,. Molecular mechanisms of drug resistance. J Pathol 2005; 205: 275-92.
-
(2005)
J Pathol
, vol.205
, pp. 275-292
-
-
Longley, D.B.1
Johnston, P.G.2
-
44
-
-
63749087499
-
The marriage of growth factor inhibitors and chemotherapy: Bliss or bust?
-
Staal S, O'Connell MJ, Allegra CJ,. The marriage of growth factor inhibitors and chemotherapy: bliss or bust? J Clin Oncol 2009; 27: 1545-8.
-
(2009)
J Clin Oncol
, vol.27
, pp. 1545-1548
-
-
Staal, S.1
O'Connell, M.J.2
Allegra, C.J.3
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