Thymidylate synthase and dihydropyrimidine dehydrogenase mRNA levels in tumor tissues and the efficacy of 5-fluorouracil in patients with non-small-cell lung cancer

Lung Cancer

Volumn 45, Issue 2, 2004, Pages 189-196

  Shintani, Yasushi ^a   Ohta, Mitsunori ^a   Hirabayashi, Hirohisa ^a   Tanaka, Hisaichi ^b   Iuchi, Keiji ^b   Nakagawa, Katsuhiro ^b   Maeda, Hajime ^b   Kido, Tetsuo ^b   Miyoshi, Shinichiro ^c   Matsuda, Hikaru ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c DOKKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

5 Fluorouracil; Dihydropyrimidine dehydrogenase; Disease free survival; Non small cell lung cancer; Real time RT PCR; Thymidylate synthase

Indexed keywords

DIHYDROPYRIMIDINE DEHYDROGENASE; FLUOROURACIL; MESSENGER RNA; THYMIDYLATE SYNTHASE;

ADJUVANT THERAPY; ADULT; AGED; ARTICLE; CANCER ADJUVANT THERAPY; CANCER RECURRENCE; CANCER STAGING; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG EFFICACY; FEMALE; GENE EXPRESSION; HUMAN; HUMAN TISSUE; LUNG NON SMALL CELL CANCER; MALE; MEDICAL INSTRUMENTATION; METASTASIS; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

AGED; BASE SEQUENCE; BIOPSY, NEEDLE; CARCINOMA, NON-SMALL-CELL LUNG; CASE-CONTROL STUDIES; CHEMOTHERAPY, ADJUVANT; CHI-SQUARE DISTRIBUTION; DIHYDROURACIL DEHYDROGENASE (NADP); FEMALE; FLUOROURACIL; HUMANS; IMMUNOHISTOCHEMISTRY; LUNG NEOPLASMS; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; NEOPLASM STAGING; PROBABILITY; PROGNOSIS; PROSPECTIVE STUDIES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SENSITIVITY AND SPECIFICITY; STATISTICS, NONPARAMETRIC; SURVIVAL ANALYSIS; THYMIDYLATE SYNTHASE; TREATMENT OUTCOME; TUMOR MARKERS, BIOLOGICAL;

EID: 3042756923     PISSN: 01695002     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lungcan.2004.01.015     Document Type: Article

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