-
1
-
-
0020412908
-
Regulation of arachidonate-induced platelet aggregation by the lipoxygenase product, 12-hydroperoxyeicosatetraenoic acid
-
Aharony D, Smith JB, and Silver MJ (1982) Regulation of arachidonate-induced platelet aggregation by the lipoxygenase product, 12-hydroperoxyeicosatetraenoic acid. Biochim Biophys Acta 718:193-200. (Pubitemid 13199615)
-
(1982)
Biochimica et Biophysica Acta
, vol.718
, Issue.2
, pp. 193-200
-
-
Aharony, D.1
Smith, J.B.2
Silver, M.J.3
-
2
-
-
0029830685
-
Inhibition of mitogen-activated protein kinase kinase does not impair primary activation of human platelets
-
Borsch-Haubold AG, Kramer RM, and Watson SP (1996) Inhibition of mitogenactivated protein kinase kinase does not impair primary activation of human platelets. Biochem J 318 (Pt 1):207-212. (Pubitemid 26283647)
-
(1996)
Biochemical Journal
, vol.318
, Issue.1
, pp. 207-212
-
-
Borsch-Haubold, A.G.1
Kramer, R.M.2
Watson, S.P.3
-
3
-
-
0022376156
-
A review of possible roles of the platelet 12-lipoxygenase
-
Brash AR (1985) A review of possible roles of the platelet 12-lipoxygenase. Circulation 72:702-707.
-
(1985)
Circulation
, vol.72
, pp. 702-707
-
-
Brash, A.R.1
-
4
-
-
0033485859
-
Regulation of c-jun-NH2 terminal kinase and extracellular-signal regulated kinase in human platelets
-
Bugaud F, Nadal-Wollbold F, Lévy-Toledano S, Rosa JP, and Bryckaert M (1999) Regulation of c-jun-NH2 terminal kinase and extracellular-signal regulated kinase in human platelets. Blood 94:3800-3805.
-
(1999)
Blood
, vol.94
, pp. 3800-3805
-
-
Bugaud, F.1
Nadal-Wollbold, F.2
Lévy-Toledano, S.3
Rosa, J.P.4
Bryckaert, M.5
-
5
-
-
0021871816
-
2 by hydroxyeicosatetraenoic acids (HETEs). A novel pharmacological mechanism for regulating free fatty acid release
-
DOI 10.1016/0006-2952(85)90701-4
-
Chang J, Blazek E, Kreft AF, and Lewis AJ (1985) Inhibition of platelet and neutrophil phospholipase A2 by hydroxyeicosatetraenoic acids (HETES). A novel pharmacological mechanism for regulating free fatty acid release. Biochem Pharmacol 34:1571-1575. (Pubitemid 15025799)
-
(1985)
Biochemical Pharmacology
, vol.34
, Issue.9
, pp. 1571-1575
-
-
Chang, J.1
Blazek, E.2
Kreft, A.F.3
Lewis, A.J.4
-
6
-
-
65549123690
-
Protein kinase Cδ differentially regulates platelet functional responses
-
Chari R, Getz T, Nagy B Jr, Bhavaraju K, Mao Y, Bynagari YS, Murugappan S, Nakayama K, and Kunapuli SP (2009) Protein kinase Cδ differentially regulates platelet functional responses. Arterioscler Thromb Vasc Biol 29:699-705.
-
(2009)
Arterioscler Thromb Vasc Biol
, vol.29
, pp. 699-705
-
-
Chari, R.1
Getz, T.2
Nagy Jr., B.3
Bhavaraju, K.4
Mao, Y.5
Bynagari, Y.S.6
Murugappan, S.7
Nakayama, K.8
Kunapuli, S.P.9
-
7
-
-
37249062653
-
12-Lipoxygenase induces apoptosis of human gastric cancer AGS cells via the ERK1/2 signal pathway
-
Chen FL, Wang XZ, Li JY, Yu JP, Huang CY, and Chen ZX (2008) 12-Lipoxygenase induces apoptosis of human gastric cancer AGS cells via the ERK1/2 signal pathway. Dig Dis Sci 53:181-187.
-
(2008)
Dig Dis Sci
, vol.53
, pp. 181-187
-
-
Chen, F.L.1
Wang, X.Z.2
Li, J.Y.3
Yu, J.P.4
Huang, C.Y.5
Chen, Z.X.6
-
8
-
-
33646177187
-
Baicalein is a potent in vitro inhibitor against both reticulocyte 15-human and platelet 12-human lipoxygenases
-
Deschamps JD, Kenyon VA, and Holman TR(2006) Baicalein is a potent in vitro inhibitor against both reticulocyte 15-human and platelet 12-human lipoxygenases. Bioorg Med Chem 14:4295-4301.
-
(2006)
Bioorg Med Chem
, vol.14
, pp. 4295-4301
-
-
Deschamps, J.D.1
Kenyon, V.A.2
Holman, T.R.3
-
9
-
-
3242770664
-
Aspirin and clopidogrel compared with clopidogrel alone after recent ischaemic stroke or transient ischaemic attack in high-risk patients (MATCH): Randomised, double-blind, placebo-controlled trial
-
and MATCH investigators
-
Diener HC, Bogousslavsky J, Brass LM, Cimminiello C, Csiba L, Kaste M, Leys D, Matias-Guiu J, Rupprecht HJ, and MATCH investigators(2004) Aspirin and clopidogrel compared with clopidogrel alone after recent ischaemic stroke or transient ischaemic attack in high-risk patients (MATCH): randomised, double-blind, placebo-controlled trial. Lancet 364:331-337.
-
(2004)
Lancet
, vol.364
, pp. 331-337
-
-
Diener, H.C.1
Bogousslavsky, J.2
Brass, L.M.3
Cimminiello, C.4
Csiba, L.5
Kaste, M.6
Leys, D.7
Matias-Guiu, J.8
Rupprecht, H.J.9
-
10
-
-
0035545994
-
12-Lipoxygenase metabolite 12(S)-HETE stimulates human pancreatic cancer cell proliferation via protein tyrosine phosphorylation and ERK activation
-
Ding XZ, Tong WG, and Adrian TE (2001) 12-Lipoxygenase metabolite 12(S)-HETE stimulates human pancreatic cancer cell proliferation via protein tyrosine phosphorylation and ERK activation. Int J Cancer 94:630-636.
-
(2001)
Int J Cancer
, vol.94
, pp. 630-636
-
-
Ding, X.Z.1
Tong, W.G.2
Adrian, T.E.3
-
11
-
-
11244273081
-
The value of clopidogrel versus aspirin in reducing atherothrombotic events: The CAPRIE Study
-
DOI 10.2165/00019053-200422004-00005
-
Durand-Zaleski I and Bertrand M (2004) The value of clopidogrel versus aspirin in reducing atherothrombotic events: the CAPRIE study. Pharmacoeconomics 22 (Suppl 4):19-27. (Pubitemid 40066090)
-
(2004)
PharmacoEconomics
, vol.22
, Issue.SUPPL. 4
, pp. 19-27
-
-
Durand-Zaleski, I.1
Bertrand, M.2
-
12
-
-
79956052911
-
Protease-activated receptor 1 (PAR1) signalling desensitization is counteracted via PAR4 signalling in human platelets
-
Fälker K, Haglund L, Gunnarsson P, Nylander M, Lindahl TL, and Grenegård M2011) Protease-activated receptor 1 (PAR1) signalling desensitization is counteracted via PAR4 signalling in human platelets. Biochem J 436:469-480.
-
(2011)
Biochem J
, vol.436
, pp. 469-480
-
-
Fälker, K.1
Haglund, L.2
Gunnarsson, P.3
Nylander, M.4
Lindahl, T.L.5
Grenegård, M.6
-
13
-
-
0027467498
-
Protein kinase C activation without membrane contact in platelets stimulated by bryostatin
-
Grabarek J and Ware JA (1993) Protein kinase C activation without membrane contact in platelets stimulated by bryostatin. J Biol Chem 268:5543-5549. (Pubitemid 23090875)
-
(1993)
Journal of Biological Chemistry
, vol.268
, Issue.8
, pp. 5543-5549
-
-
Grabarek, J.1
Ware, J.A.2
-
15
-
-
77949279691
-
Diverse functions of protein kinase C isoforms in platelet activation and thrombus formation
-
Harper MT and Poole AW (2010) Diverse functions of protein kinase C isoforms in platelet activation and thrombus formation. J Thromb Haemost 8:454-462.
-
(2010)
J Thromb Haemost
, vol.8
, pp. 454-462
-
-
Harper, M.T.1
Poole, A.W.2
-
16
-
-
79551480210
-
Protease-activated receptor signaling in platelets activates cytosolic phospholipase A2α differently for cyclooxygenase-1 and 12-lipoxygenase catalysis
-
Holinstat M, Boutaud O, Apopa PL, Vesci J, Bala M, Oates JA, and Hamm HE (2011) Protease-activated receptor signaling in platelets activates cytosolic phospholipase A2α differently for cyclooxygenase-1 and 12-lipoxygenase catalysis. Arterioscler Thromb Vasc Biol 31:435-442.
-
(2011)
Arterioscler Thromb Vasc Biol
, vol.31
, pp. 435-442
-
-
Holinstat, M.1
Boutaud, O.2
Apopa, P.L.3
Vesci, J.4
Bala, M.5
Oates, J.A.6
Hamm, H.E.7
-
17
-
-
79961219253
-
Discovery of potent and selective inhibitors of human platelet-type 12- Lipoxygenase
-
Kenyon V, Rai G, Jadhav A, Schultz L, Armstrong M, Jameson JB 2nd, Perry S, Joshi N, Bougie JM, Leister W, et al. (2011) Discovery of potent and selective inhibitors of human platelet-type 12- lipoxygenase. J Med Chem 54:5485-5497.
-
(2011)
J Med Chem
, vol.54
, pp. 5485-5497
-
-
Kenyon, V.1
Rai, G.2
Jadhav, A.3
Schultz, L.4
Armstrong, M.5
Jameson II, J.B.6
Perry, S.7
Joshi, N.8
Bougie, J.M.9
Leister, W.10
-
18
-
-
0027502928
-
Selective regulation of protein kinase C isoenzymes by oleic acid in human platelets
-
Khan WA, Blobe G, Halpern A, Taylor W, Wetsel WC, Burns D, Loomis C, and Hannun YA (1993) Selective regulation of protein kinase C isoenzymes by oleic acid in human platelets. J Biol Chem 268:5063-5068. (Pubitemid 23081631)
-
(1993)
Journal of Biological Chemistry
, vol.268
, Issue.7
, pp. 5063-5068
-
-
Khan, W.A.1
Blobe, G.2
Halpern, A.3
Taylor, W.4
Wetsel, W.C.5
Burns, D.6
Loomis, C.7
Hannun, Y.A.8
-
19
-
-
79952057097
-
PKC inhibitors RO 31-8220 and Go 6983 enhance epinephrine-induced platelet aggregation in catecholamine hypo-responsive platelets by enhancing Akt phosphorylation
-
Kim SY, Kim S, Kim JM, Jho EH, Park S, Oh D, and Yun-Choi HS (2011) PKC inhibitors RO 31-8220 and Go 6983 enhance epinephrine-induced platelet aggregation in catecholamine hypo-responsive platelets by enhancing Akt phosphorylation. BMB Rep 44:140-145.
-
(2011)
BMB Rep
, vol.44
, pp. 140-145
-
-
Kim, S.Y.1
Kim, S.2
Kim, J.M.3
Jho, E.H.4
Park, S.5
Oh, D.6
Yun-Choi, H.S.7
-
20
-
-
61749097572
-
PKCα regulates platelet granule secretion and thrombus formation in mice
-
Konopatskaya O, Gilio K, Harper MT, Zhao Y, Cosemans JM, Karim ZA, Whiteheart SW, Molkentin JD, Verkade P, Watson SP, et al. (2009) PKCα regulates platelet granule secretion and thrombus formation in mice. J Clin Invest 119:399-407.
-
(2009)
J Clin Invest
, vol.119
, pp. 399-407
-
-
Konopatskaya, O.1
Gilio, K.2
Harper, M.T.3
Zhao, Y.4
Cosemans, J.M.5
Karim, Z.A.6
Whiteheart, S.W.7
Molkentin, J.D.8
Verkade, P.9
Watson, S.P.10
-
21
-
-
72749088774
-
Protein kinase Cα: Disease regulator and therapeutic target
-
Konopatskaya O and Poole AW (2010) Protein kinase Cα: disease regulator and therapeutic target. Trends Pharmacol Sci 31:8-14.
-
(2010)
Trends Pharmacol Sci
, vol.31
, pp. 8-14
-
-
Konopatskaya, O.1
Poole, A.W.2
-
23
-
-
0141457601
-
Targeted lipidomics using electron capture atmospheric pressure chemical ionization mass spectrometry
-
Lee SH, Williams MV, DuBois RN, and Blair IA (2003) Targeted lipidomics using electron capture atmospheric pressure chemical ionization mass spectrometry. Rapid Commun Mass Spectrom 17:2168-2176. (Pubitemid 37203705)
-
(2003)
Rapid Communications in Mass Spectrometry
, vol.17
, Issue.19
, pp. 2168-2176
-
-
Lee, S.H.1
Williams, M.V.2
DuBois, R.N.3
Blair, I.A.4
-
24
-
-
0029047360
-
12(S)-Hydroxyeicosatetraenoic acid and 13(S)-hydroxyoctadecadienoic acid regulation of protein kinase C-α in melanoma cells: Role of receptor-mediated hydrolysis of inositol phospholipids
-
Liu B, Khan WA, Hannun YA, Timar J, Taylor JD, Lundy S, Butovich I, and Honn KV (1995) 12(S)-Hydroxyeicosatetraenoic acid and 13(S)- hydroxyoctadecadienoic acid regulation of protein kinase C-α in melanoma cells: role of receptor-mediated hydrolysis of inositol phospholipids. Proc Natl Acad Sci USA 92:9323-9327.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 9323-9327
-
-
Liu, B.1
Khan, W.A.2
Hannun, Y.A.3
Timar, J.4
Taylor, J.D.5
Lundy, S.6
Butovich, I.7
Honn, K.V.8
-
25
-
-
2442676785
-
Anti-thrombotic and anticoagulant treatment in interventional cardiology
-
Mahanonda N (1998) Anti-thrombotic and anticoagulant treatment in interventional cardiology. J Med Assoc Thai 81:42-46.
-
(1998)
J Med Assoc Thai
, vol.81
, pp. 42-46
-
-
Mahanonda, N.1
-
26
-
-
0021340763
-
2+-dependent protein kinase
-
McPhail LC, Clayton CC, and Snyderman R (1984) A potential second messenger role for unsaturated fatty acids: activation of Ca2+ -dependent protein kinase. Science 224:622-625. (Pubitemid 14137535)
-
(1984)
Science
, vol.224
, Issue.4649
, pp. 622-625
-
-
McPhail, L.C.1
Clayton, C.C.2
Snyderman, R.3
-
27
-
-
0037145838
-
Platelet ERK2 activation by thrombin is dependent on calcium and conventional protein kinases C but not Raf-1 or B-Raf
-
DOI 10.1016/S0014-5793(02)03587-1, PII S0014579302035871
-
Nadal-Wollbold F, Pawlowski M, Lévy-Toledano S, Berrou E, Rosa JP, and Bryckaert M (2002) Platelet ERK2 activation by thrombin is dependent on calcium and conventional protein kinases C but not Raf-1 or B-Raf. FEBS Lett 531:475-482. (Pubitemid 35336072)
-
(2002)
FEBS Letters
, vol.531
, Issue.3
, pp. 475-482
-
-
Nadal-Wollbold, F.1
Pawlowski, M.2
Levy-Toledano, S.3
Berrou, E.4
Rosa, J.-P.5
Bryckaert, M.6
-
28
-
-
0030434491
-
Platelet lipoxygenase inhibitors attenuate thrombin- and thromboxane mimetic-induced intracellular calcium mobilization and platelet aggregation
-
Nyby MD, Sasaki M, Ideguchi Y, Wynne HE, Hori MT, Berger ME, Golub MS, Brickman AS, and Tuck ML (1996) Platelet lipoxygenase inhibitors attenuatethrombin- and thromboxane mimetic-induced intracellular calcium mobilization and platelet aggregation. J Pharmacol Exp Ther 278:503-509. (Pubitemid 27167012)
-
(1996)
Journal of Pharmacology and Experimental Therapeutics
, vol.278
, Issue.2
, pp. 503-509
-
-
Nyby, M.D.1
Sasaki, M.2
Ideguchi, Y.3
Wynne, H.E.4
Hori, M.T.5
Berger, M.E.6
Golub, M.S.7
Brickman, A.S.8
Tuck, M.L.9
-
29
-
-
28244459634
-
Low-dose aspirin for the prevention of atherothrombosis
-
DOI 10.1056/NEJMra052717
-
Patrono C, García Rodríguez LA, Landolfi R, and Baigent C (2005) Low-dose aspirin for the prevention of atherothrombosis. N Engl J Med 353:2373-2383. (Pubitemid 41713749)
-
(2005)
New England Journal of Medicine
, vol.353
, Issue.22
, pp. 2373-2383
-
-
Patrono, C.1
Garcia, R.L.A.2
Landolfi, R.3
Baigent, C.4
-
30
-
-
36149000163
-
Lipoxygenase metabolism: Roles in tumor progression and survival
-
DOI 10.1007/s10555-007-9098-3, Forty Years of Metastasis Research: A Tribute to Dr. Isaiah J. Fidler
-
Pidgeon GP, Lysaght J, Krishnamoorthy S, Reynolds JV, O'Byrne K, Nie D, and Honn KV (2007) Lipoxygenase metabolism: roles in tumor progression and survival. Cancer Metastasis Rev 26:503-524. (Pubitemid 350115127)
-
(2007)
Cancer and Metastasis Reviews
, vol.26
, Issue.3-4
, pp. 503-524
-
-
Pidgeon, G.P.1
Lysaght, J.2
Krishnamoorthy, S.3
Reynolds, J.V.4
O'Byrne, K.5
Nie, D.6
Honn, K.V.7
-
32
-
-
79952423160
-
Functional characterization of mutations in inherited human cPLA2 deficiency
-
Reed KA, Tucker DE, Aloulou A, Adler D, Ghomashchi F, Gelb MH, Leslie CC, Oates JA, and Boutaud O (2011) Functional characterization of mutations in inherited human cPLA2 deficiency. Biochemistry 50:1731-1738.
-
(2011)
Biochemistry
, vol.50
, pp. 1731-1738
-
-
Reed, K.A.1
Tucker, D.E.2
Aloulou, A.3
Adler, D.4
Ghomashchi, F.5
Gelb, M.H.6
Leslie, C.C.7
Oates, J.A.8
Boutaud, O.9
-
33
-
-
0027405757
-
Activation of myelin basic protein and S6 peptide kinases in phorbol ester- and PAF-treated sheep platelets
-
DOI 10.1016/0167-4889(93)90057-V
-
Samiei M, Sanghera JS, and Pelech SL (1993) Activation of myelin basic protein and S6 peptide kinases in phorbol ester- and PAF-treated sheep platelets. Biochim Biophys Acta 1176:287-298. (Pubitemid 23113771)
-
(1993)
Biochimica et Biophysica Acta - Molecular Cell Research
, vol.1176
, Issue.3
, pp. 287-298
-
-
Samiei, M.1
Sanghera, J.S.2
Pelech, S.L.3
-
34
-
-
0035656189
-
Regulation of c-fos induction in lens epithelial cells by 12(S)HETE-dependent activation of PKC
-
Seth RK, Haque MS, and Zelenka PS (2001) Regulation of c-fos induction in lens epithelial cells by 12(S)HETE-dependent activation of PKC. Invest Ophthalmol Vis Sci 42:3239-3246. (Pubitemid 33740686)
-
(2001)
Investigative Ophthalmology and Visual Science
, vol.42
, Issue.13
, pp. 3239-3246
-
-
Seth, R.K.1
Haque, M.S.R.2
Zelenka, P.S.3
-
35
-
-
0024543387
-
Selective activation of the γ-subspecies of protein kinase C from bovine cerebellum by arachidonic acid and its lipoxygenase metabolites
-
DOI 10.1016/0014-5793(89)80125-5
-
Shearman MS, Naor Z, Sekiguchi K, Kishimoto A, and Nishizuka Y (1989) Selective activation of the γ-subspecies of protein kinase C from bovine cerebellum by arachidonic acid and its lipoxygenase metabolites. FEBS Lett 243:177-182. (Pubitemid 19037476)
-
(1989)
FEBS Letters
, vol.243
, Issue.2
, pp. 177-182
-
-
Shearman, M.S.1
Naor, Z.2
Sekiguchi, K.3
Kishimoto, A.4
Nishizuka, Y.5
-
36
-
-
34147170380
-
Dual role of platelet protein kinase C in thrombus formation: Stimulation of pro-aggregatory and suppression of procoagulant activity in platelets
-
DOI 10.1074/jbc.M611367200
-
Strehl A, Munnix IC, Kuijpers MJ, van der Meijden PE, Cosemans JM, Feijge MA, Nieswandt B, and Heemskerk JW (2007) Dual role of platelet protein kinase C in thrombus formation: stimulation of pro-aggregatory and suppression of procoagulant activity in platelets. J Biol Chem 282:7046-7055. (Pubitemid 47093677)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.10
, pp. 7046-7055
-
-
Strehl, A.1
Munnix, I.C.A.2
Kuijpers, M.J.E.3
Van Der, M.P.E.J.4
Cosemans, J.M.E.M.5
Feijge, M.A.H.6
Nieswandt, B.7
Heemskerk, J.W.M.8
-
37
-
-
0034624064
-
Eicosanoid activation of extracellular signal-regulated kinase 1/2 in human epidermoid carcinoma cells
-
DOI 10.1074/jbc.M002673200
-
Szekeres CK, Tang K, Trikha M, and Honn KV (2000) Eicosanoid activation of extracellular signal-regulated kinase1/2 in human epidermoid carcinoma cells. J Biol Chem 275:38831-38841. (Pubitemid 32009220)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.49
, pp. 38831-38841
-
-
Szekeres, C.K.1
Tang, K.2
Trikha, M.3
Honn, K.V.4
-
38
-
-
77951214211
-
Phospholipid-esterified eicosanoids are generated in agonist-activated human platelets and enhance tissue factor-dependent thrombin generation
-
Thomas CP, Morgan LT, Maskrey BH, Murphy RC, Kühn H, Hazen SL, Goodall AH, Hamali HA, Collins PW, and O'Donnell VB (2010) Phospholipid- esterified eicosanoids are generated in agonist-activated human platelets and enhance tissue factor-dependent thrombin generation. J Biol Chem 285:6891-6903.
-
(2010)
J Biol Chem
, vol.285
, pp. 6891-6903
-
-
Thomas, C.P.1
Morgan, L.T.2
Maskrey, B.H.3
Murphy, R.C.4
Kühn, H.5
Hazen, S.L.6
Goodall, A.H.7
Hamali, H.A.8
Collins, P.W.9
O'Donnell, V.B.10
-
41
-
-
33749551428
-
2 release
-
DOI 10.1074/jbc.M604504200
-
Yacoub D, Théorêt JF, Villeneuve L, Abou-Saleh H, Mourad W, Allen BG, and Merhi Y (2006) Essential role of protein kinase Cδ in platelet signaling, αIIbβ3 activation, and thromboxane A2 release. J Biol Chem 281:30024-30035. (Pubitemid 44537010)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.40
, pp. 30024-30035
-
-
Yacoub, D.1
Theoret, J.-F.2
Villeneuve, L.3
Abou-Saleh, H.4
Mourad, W.5
Allen, B.G.6
Merhi, Y.7
|