Dual role of platelet protein kinase C in thrombus formation: Stimulation of pro-aggregatory and suppression of procoagulant activity in platelets

Journal of Biological Chemistry

Volumn 282, Issue 10, 2007, Pages 7046-7055

  Strehl, Amrei ^a,b   Munnix, Imke C A ^a   Kuijpers, Marijke J E ^a   Van Der Meijden, Paola E J ^a   Cosemans, Judith M E M ^a   Feijge, Marion A H ^a   Nieswandt, Bernhard ^b   Heemskerk, Johan W M ^a,c  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b UNIVERSITY OF WÜRZBURG   (Germany)

^c MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

PLATELET AGGREGATION; PROCOAGULANT PHOSPHATIDYLSERINE;

BIOCHEMISTRY; PLASMA (HUMAN); PLATELETS; PROTEINS;

ENZYME KINETICS;

CALCIUM; INTEGRIN; PHOSPHATIDYLSERINE; PROCOAGULANT; PROTEIN KINASE C; THROMBIN; VERY LATE ACTIVATION ANTIGEN 3; FIBRINOGEN RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLOOD CLOTTING; CALCIUM SIGNALING; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME REGULATION; ENZYME RELEASE; ENZYME REPRESSION; FEMALE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS REGULATION; PROTEIN VARIANT; SIGNAL TRANSDUCTION; THROMBOCYTE ADHESION; THROMBOCYTE AGGREGATION; THROMBOCYTE AGGREGATION INHIBITION; THROMBOGENESIS; WILD TYPE; ANIMAL; C57BL MOUSE; DRUG ANTAGONISM; ENZYMOLOGY; HUMAN; METABOLISM; PHYSIOLOGY; SHEAR STRENGTH; THROMBOCYTE; THROMBOSIS;

MURINAE; MUS;

ANIMALS; BLOOD COAGULATION; BLOOD PLATELETS; CALCIUM; CALCIUM SIGNALING; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HUMANS; MICE; MICE, INBRED C57BL; PLATELET AGGREGATION; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; PROTEIN KINASE C; SHEAR STRENGTH; THROMBOSIS;

EID: 34147170380     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M611367200     Document Type: Article

References (50)

1. Tsukuda, M., Asaoka, Y., Sekiguchi, K., Kikkawa, U., and Nishizuka, Y. (1988) Biochem. Biophys. Res. Commun. 155, 1387-1395
2. Quinton, T. M., Kim, S., Dangelmaier, C., Dorsam, R. T., Jin, J., Daniel, J. L., and Kunapuli, S. P. (2002) Biochem. J. 368, 535-543
3. Siess, W., and Lapetina, E. G. (1988) Biochem. J. 255, 309-318
4. Tabuchi, A., Yoshioka, A., Higashi, T., Shirakawa, R., Nishioka, H., Kita, T., and Horiuchi, H. (2003) J. Biol. Chem. 278, 26374-26379
5. Rink, T. J., Sanchez, A., and Hallam, T. J. (1983) Nature 305, 317-319
6. Walker, T. R., and Watson, S. P. (1993) Biochem. J. 289, 277-282
7. Yoshioka, A., Shirakawa, R., Nishioka, H., Tabuchi, A., Higashi, T., Ozaki, H., Yamamoto, A., Kita, T., and Horiuchi, H. (2001) J. Biol. Chem. 276, 39379-39385
8. Jin, J., and Kunapoli, S. P. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 8070-8074
9. Paul, B. Z. S., Jin, J. G., and Kunapuli, S. P. (1999) J. Biol. Chem. 274, 29108-29114
10. Van Willigen, G., and Akkerman, J. W. N. (1991) Biochem. J. 273, 115-120
11. Hers, I., Donath, J., Litjens, P. E. H. M., van Willigen, G., and Akkerman, J. W. N. (2000) Arterioscler. Thromb. Vasc. Biol. 20, 1651-1660
12. Packham, M. A., Livne, A. A., Ruben, D. H., and Rand, M. L. (1993) Biochem. J. 290, 849-856
13. Crittenden, J. R., Bergmeier, W., Zhang, Y., Piffath, C. L., Liang, Y., Wagner, D. D., Housman, D. E., and Graybiel, A. M. (2004) Nat. Med. 10, 982-986
14. Hartwig, J. H., Kung, S., Kovacsovics, T., Janmey, P. A., Cantley, L. C., Stossel, T. P., and Toker, A. (1996) J. Biol. Chem. 271, 32986-32993
15. Buensuceso, C. S., Obergfell, A., Soriani, A., Eto, K., Kiosses, W. B., Arias-Salgado, E. G., Kawakami, T., and Shattil, S. J. (2005) J. Biol. Chem. 280, 644-653
16. Pollock, W. K., Sage, S. O., and Rink, T. J. (1987) FEBS Lett. 210, 132-136
17. King, W. G., and Rittenhouse, S. E. (1989) J. Biol. Chem. 264, 6070-6074
18. Rosado, J. A., and Sage, S. O. (2000) J. Physiol. (Lond.) 529, 159-169
19. Hardy, A. R., Conley, P. B., Luo, J., Benovic, J. L., Poole, A. W., and Mundell, S. J. (2005) Blood 105, 3552-3560
20. Chen, H., and Kahn, M. L. (2003) Mol. Cell. Biol. 23, 4764-4777
21. Kuijpers, M. J. E., Schulte, V., Bergmeier, W., Lindhout, T., Brakebusch, C., Offermanns, S., Fässler, R., Heemskerk, J. W. M., and Nieswandt, B. (2003) FASEB J. 17, 685-687
22. Siljander, P. R. M., Munnix, I. C. A., Smethurst, P. A., Deckmyn, H., Lindhout, T., Ouwehand, W. H., Farndale, R. W., and Heemskerk, J. W. M. (2004) Blood 103, 1333-1341
23. Auger, J. M., Kuijpers, M. J. E., Senis, Y. A., Watson, S. P., and Heemskerk, J. W. M. (2005) FASEB J. 19, 825-827
24. Ruggeri, Z. M. (2002) Nat. Med. 8, 1227-1234
25. Offermanns, S., Toombs, C. F., Hu, Y. H., and Simon, M. I. (1997) Nature 389, 183-186
26. Heemskerk, J. W. M., Bevers, E. M., and Lindhout, T. (2002) Thromb. Haemostasis 88, 186-193
27. Nieswandt, B., Schulte, V., Bergmeier, W., Mokhtari-Nejad, R., Rackebrandt, K., Cazenave, J. P., Ohlmann, P., Gachet, C., and Zirngibl, H. (2001) J. Exp. Med. 193, 459-469
28. Grüner, S., Prostredna, M., Aktas, B., Moers, A., Schulte, V., Krieg, T., Offermanns, S., Eckes, B., and Nieswandt, B. (2004) Circulation 110, 2946-2951
29. Munnix, I. C. A., Strehl, A., Kuijpers, M. J. E., Auger, J. M., van Zandvoort, M. A. M. J., oude Egbrink, M., Nieswandt, B., and Heemskerk, J. W. M. (2005) Arterioscler. Thromb. Vasc. Biol. 25, 2673-2678
30. Polanowska-Grabowska, R., and Gear, A. R. L. (1999) Arterioscler. Thromb. Vasc. Biol. 19, 3044-3054
31. Siljander, P., Farndale, R. W., Feijge, M. A. H., Comfurius, P., Kos, S., Bevers, E. M., and Heemskerk, J. W. M. (2001) Arterioscler. Thromb. Vasc. Biol. 21, 618-627
32. Schulte, V., Snell, D., Bergmeier, W., Zirngibl, H., Watson, S. P., and Nieswandt, B. (2001) J. Biol. Chem. 276, 364-368
33. Nieswandt, B., Brakebusch, C., Bergmeier, W., Schulte, V., Bouvard, D., Mohtari-Nejad, R., Lindhout, T., Heemskerk, J. W. M., Zirngibl, H., and Fässler, R. (2001) EMBO J. 20, 2120-2130
34. Van der Meijden, P. E. J., Feijge, M. A. H., Giesen, P. L. A., Huijberts, M., van Raak, E. P. M., and Heemskerk, J. W. M. (2005) Thromb. Haemostasis 93, 1128-1137
35. Grüner, S., Prostredna, M., Schulte, V., Krieg, T., Eckes, B., Brakebusch, C., and Nieswandt, B. (2003) Blood 102, 4021-4027
36. Orr, J. W., Keranen, L. M., and Newton, A. C. (1992) J. Biol. Chem. 267, 15263-15266
37. Cauwenberghs, S., Feijge, M. A. H., Hageman, G., Hoylaerts, M. F., Akkerman, J. W. N., Curvers, J., and Heemskerk, J. W. M. (2006) Transfusion (Bethesda) 46, 1018-1028
38. Heemskerk, J. W. M., Feijge, M. A. H., Henneman, L., Rosing, J., and Hemker, H. C. (1997) Eur. J. Biochem. 249, 547-555
39. Heemskerk, J. W. M., Willems, G. M., Rook, M. B., and Sage, S. O. (2001) J. Physiol. (Lond.) 535, 625-635
40. Lecut, C., Schoolmeester, A., Kuijpers, M. J. E., Broers, J. L. V., van Zandvoort, M. A. M. J., Vanhoorelbeke, K., Deckmyn, H., Jandrot-Perrus, M., and Heemskerk, J. W. M. (2004) Arterioscler. Thromb. Vasc. Biol. 24, 1727-1733
41. Vanschoonbeek, K., Feijge, M. A. H., van Kampen, R. J. W., Kenis, H., Hemker, H. C., Giesen, P. L. A., and Heemskerk, J. W. M. (2004) J. Thromb. Haemostasis. 2, 476-484
42. Martiny-Baron, G., Kazanietz, M. G., Mischak, H., Blumberg, P. M., Kochs, G., Hug, H., Marme, D., and Schachtele, C. (1993) J. Biol. Chem. 268, 9194-9197
43. Wilkinson, S. E., Parker, P. J., and Nixon, J. S. (1993) Biochem. J. 294, 335-337
44. Shattil, S. J., and Brass, L. F. (1987) J. Biol. Chem. 262, 992-1000
45. Pula, G., Crosby, D., Baker, J., and Poole, A. W. (2005) J. Biol. Chem. 280, 7194-7205
46. Quinton, T. M., Ozdener, F., Dangelmaier, C., Daniel, J. L., and Kunapuli, S. P. (2002) Blood 99, 3228-3234
47. Yacoub, D., Theoret, J. F., Villeneuve, L., Abou-Saleh, H., Mourad, W., and Allen, B. G. (2006) J. Biol. Chem. 281, 30024-30035
48. Reither, G., Schaefer, M., and Lipp, P. (2006) J. Cell Biol. 174, 521-533
49. Giuliano, S., Nesbitt, W. S., Rooney, M., and Jackson, S. P. (2003) Biochem. J. 372, 163-172
50. Bernardi, B., Guidetti, G. F., Campus, F., Crittenden, J. R., Graybiel, A. M., Balduini, C., and Torti, M. (2006) Blood 107, 2728-2735