Loss of the tumor suppressor Pten promotes proliferation of Drosophila melanogaster cells in vitro and gives rise to continuous cell lines

PLoS ONE

Volumn 7, Issue 2, 2012, Pages

  Justiniano, Steven E ^a   Mathew, Anne ^a   Mitra, Sayan ^a   Manivannan, Sathiya N ^a   Simcox, Amanda ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RAS PROTEIN; DROSOPHILA PROTEIN; MUTANT PROTEIN; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PTEN PROTEIN, DROSOPHILA; TUMOR SUPPRESSOR PROTEIN;

ANIMAL CELL; ARTICLE; CELL LINE; CELL MUTANT; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; EMBRYO; GENE EXPRESSION; GENE LOSS; GENE MUTATION; IN VITRO STUDY; INCUBATION TIME; NONHUMAN; PTEN GENE; SCREENING TEST; SURVIVAL TIME; TUMOR SUPPRESSOR GENE; WILD TYPE; ANIMAL; BIOASSAY; CYTOLOGY; ENZYMOLOGY; GENETICS; HYPERPLASIA; METABOLISM; MUTATION; NEOPLASM; PATHOLOGY; TIME;

ANIMALS; BIOLOGICAL ASSAY; CELL LINE; CELL PROLIFERATION; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; HYPERPLASIA; MUTANT PROTEINS; MUTATION; NEOPLASMS; PTEN PHOSPHOHYDROLASE; RAS PROTEINS; TIME FACTORS; TUMOR SUPPRESSOR PROTEINS;

EID: 84857407891     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0031417     Document Type: Article

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