Molecular interactions of porcine circoviruses type 1 and type 2 with its host

Virus Research

Volumn 164, Issue 1-2, 2012, Pages 54-60

  Mankertz, Annette ^a  

^a ROBERT KOCH INSTITUTE   (Germany)

Author keywords

Host; Interaction; Pathogen; PCVD; Porcine circovirus

Indexed keywords

HEAT SHOCK PROTEIN 27; HELICASE; MYC PROTEIN; NUCLEOPHOSMIN; NUCLEOSOME ASSEMBLY PROTEIN 1; THYMINE DNA GLYCOSYLASE; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 9; TRANSCRIPTOME; UBIQUITIN PROTEIN LIGASE E3;

CARBOXY TERMINAL SEQUENCE; CIRCOVIRUS; CIRCOVIRUS TYPE 1; CIRCOVIRUS TYPE 2; DNA REPLICATION; GENETIC VARIABILITY; GENOMICS; HEART MUSCLE; HEPATITIS C VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; INNATE IMMUNITY; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DNA INTERACTION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEOMICS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; REVIEW; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; VIRUS CELL INTERACTION; VIRUS GENOME; VIRUS REPLICATION; VIRUS VIRULENCE;

ANIMALS; CIRCOVIRUS; DNA, VIRAL; HOST-PATHOGEN INTERACTIONS; PROTEIN BINDING; SWINE; VIRAL PROTEINS;

PORCINE CIRCOVIRUS; SUS;

EID: 84857362269     PISSN: 01681702     EISSN: 18727492     Source Type: Journal    
DOI: 10.1016/j.virusres.2011.11.001     Document Type: Review

References (76)

1. Adams D.J., van der Weyden L., Mayeda A., Stamm S., Morris B.J., Rasko J.E. ZNF265 - a novel spliceosomal protein able to induce alternative splicing. J. Cell Biol. 2001, 154(1):25-32.
2. Allan G., Meehan B., Todd D., Kennedy S., McNeilly F., Ellis J., Clark E.G., Harding J., Espuna E., Botner A., Charreyre C. Novel porcine circoviruses from pigs with wasting disease syndromes. Vet. Rec. 1998, 142(17):467-468.
3. Allday M.J. How does Epstein-Barr virus (EBV) complement the activation of Myc in the pathogenesis of Burkitt's lymphoma?. Semin. Cancer Biol. 2009, 19(6):366-376.
4. Balmelli C., Steiner E., Moulin H., Peduto N., Herrmann B., Summerfield A., McCullough K. Porcine circovirus type 2 DNA influences cytoskeleton rearrangements in plasmacytoid and monocyte-derived dendritic cells. Immunology 2011, 132(1):57-65.
5. Baylis S.A., Finsterbusch T., Bannert N., Blumel J., Mankertz A. Analysis of porcine circovirus type 1 detected in Rotarix vaccine. Vaccine 2011, 29(4):690-697.
6. Beatch M.D., Everitt J.C., Law L.J., Hobman T.C. Interactions between rubella virus capsid and host protein p32 are important for virus replication. J. Virol. 2005, 79(16):10807-10820.
7. Bernard P., Drogat J., Dheur S., Genier S., Javerzat J.P. Splicing factor Spf30 assists exosome-mediated gene silencing in fission yeast. Mol. Cell. Biol. 2010, 30(5):1145-1157.
8. Berro R., Kehn K., de la Fuente C., Pumfery A., Adair R., Wade J., Colberg-Poley A.M., Hiscott J., Kashanchi F. Acetylated Tat regulates human immunodeficiency virus type 1 splicing through its interaction with the splicing regulator p32. J. Virol. 2006, 80(7):3189-3204.
9. Bratanich A., Blanchetot A. A gene similar to the human hyaluronan-mediated motility receptor (RHAMM) gene is upregulated during Porcine Circovirus type 2 infection. Virus Genes 2006, 32(2):145-152.
10. Chaiyakul M., Hsu K., Dardari R., Marshall F., Czub M. Cytotoxicity of ORF3 proteins from a nonpathogenic and a pathogenic porcine circovirus. J. Virol. 2010, 84(21):11440-11447.
11. Chang H.W., Jeng C.R., Lin C.M., Liu J.J., Chang C.C., Tsai Y.C., Chia M.Y., Pang V.F. The involvement of Fas/FasL interaction in porcine circovirus type 2 and porcine reproductive and respiratory syndrome virus co-inoculation-associated lymphocyte apoptosis in vitro. Vet. Microbiol. 2007, 122(1-2):72-82.
12. Choi Y., Kwon Y.C., Kim S.I., Park J.M., Lee K.H., Ahn B.Y. A hantavirus causing hemorrhagic fever with renal syndrome requires gC1qR/p32 for efficient cell binding and infection. Virology 2008, 381(2):178-183.
13. Clarke W.T., Edwards B., McCullagh K.J., Kemp M.W., Moorwood C., Sherman D.L., Burgess M., Davies K.E. Syncoilin modulates peripherin filament networks and is necessary for large-calibre motor neurons. J. Cell Sci. 2010, 123(Pt 15):2543-2552.
14. Claus C., Chey S., Heinrich S., Reins M., Richardt B., Pinkert S., Fechner H., Gaunitz F., Schäfer I., Seibel P., Liebert U.G. Involvement of p32 and microtubules in alteration of mitochondrial functions by rubella virus. J. Virol. 2011, 85(8):3881-3892.
15. Ellis J., Hassard L., Clark E., Harding J., Allan G., Willson P., Strokappe J., Martin K., McNeilly F., Meehan B., Todd D., Haines D. Isolation of circovirus from lesions of pigs with postweaning multisystemic wasting syndrome. Can. Vet. J. 1998, 39(1):44-51.
16. Falini B., Nicoletti I., Bolli N., Martelli M.P., Liso A., Gorello P., Mandelli F., Mecucci C., Martelli M.F. Translocations and mutations involving the nucleophosmin (NPM1) gene in lymphomas and leukemias. Haematologica 2007, 92(4):519-532.
17. Fan C., Ouyang P., Timur A.A., He P., You S.A., Hu Y., Ke T., Driscoll D.J., Chen Q., Wang Q.K. Novel roles of GATA1 in regulation of angiogenic factor AGGF1 and endothelial cell function. J. Biol. Chem. 2009, 284(35):23331-23343.
18. Fenaux M., Opriessnig T., Halbur P.G., Elvinger F., Meng X.J. A chimeric porcine circovirus (PCV) with the immunogenic capsid gene of the pathogenic PCV type 2 (PCV2) cloned into the genomic backbone of the nonpathogenic PCV1 induces protective immunity against PCV2 infection in pigs. J. Virol. 2004, 78(12):6297-6303.
19. Finsterbusch T., Mankertz A. Porcine circoviruses - small but powerful. Virus Res. 2009, 143(2):177-183.
20. Finsterbusch T., Steinfeldt T., Caliskan R., Mankertz A. Analysis of the subcellular localization of the proteins Rep, Rep' and Cap of porcine circovirus type 1. Virology 2005, 343(1):36-46.
21. Finsterbusch T., Steinfeldt T., Doberstein K., Rodner C., Mankertz A. Interaction of the replication proteins and the capsid protein of porcine circovirus type 1 and 2 with host proteins. Virology 2009.
22. Giorgini F., Guidetti P., Nguyen Q., Bennett S.C., Muchowski P.J. A genomic screen in yeast implicates kynurenine 3-monooxygenase as a therapeutic target for Huntington disease. Nat. Genet. 2005, 37(5):526-531.
23. Goodman A.G., Smith J.A., Balachandran S., Perwitasari O., Proll S.C., Thomas M.J., Korth M.J., Barber G.N., Schiff L.A., Katze M.G. The cellular protein P58IPK regulates influenza virus mRNA translation and replication through a PKR-mediated mechanism. J. Virol. 2007, 81(5):2221-2230.
24. Guan Z., Liu D., Mi S., Zhang J., Ye Q., Wang M., Gao G.F., Yan J. Interaction of Hsp40 with influenza virus M2 protein: implications for PKR signaling pathway. Protein Cell 2010, 1(10):944-955.
25. Hansen C.G., Howard G., Nichols B.J. Pacsin 2 is recruited to caveolae and functions in caveolar biogenesis. J. Cell Sci. 2011, 124(Pt 16):2777-2785.
26. Hartl F.U. Molecular chaperones in cellular protein folding. Nature 1996, 381(6583):571-579.
27. Huang X., Yuan W., Huang W., Bai Y., Deng Y., Zhu C., Liang P., Li Y., Du X., Liu M., Wang Y., Wu X. ZNF569, a novel KRAB-containing zinc finger protein, suppresses MAPK signaling pathway. Biochem. Biophys. Res. Commun. 2006, 346(3):621-628.
28. Jiang J., Casalegno-Garduno R., Chen H., Schmitt A., Schmitt M., Maxwell C.A. Multifunctional proteins bridge mitosis with motility and cancer with inflammation and arthritis. ScientificWorldJournal 2010, 10:1244-1257.
29. Johnstone R.W., See R.H., Sells S.F., Wang J., Muthukkumar S., Englert C., Haber D.A., Licht J.D., Sugrue S.P., Roberts T., Rangnekar V.M., Shi Y. A novel repressor, Par-4, modulates transcription and growth suppression functions of the Wilms' tumor suppressor WT1. Mol. Cell. Biol. 1996, 16(12):6945-6956.
30. Karuppannan A.K., Liu S., Jia Q., Selvaraj M., Kwang J. Porcine circovirus type 2 ORF3 protein competes with p53 in binding to Pirh2 and mediates the deregulation of p53 homeostasis. Virology 2010, 398(1):1-11.
31. Kim J.H., Park S.M., Kang M.R., Oh S.Y., Lee T.H., Muller M.T., Chung I.K. Ubiquitin ligase MKRN1 modulates telomere length homeostasis through a proteolysis of hTERT. Genes Dev. 2005, 19(7):776-781.
32. Knox C., Luke G.A., Blatch G.L., Pesce E.R. Heat shock protein 40 (Hsp40) plays a key role in the virus life cycle. Virus Res. 2011.
33. Ko A., Lee E.W., Yeh J.Y., Yang M.R., Oh W., Moon J.S., Song J. MKRN1 induces degradation of West Nile virus capsid protein by functioning as an E3 ligase. J. Virol. 2010, 84(1):426-436.
34. Kumar M., Mitra D. Heat shock protein 40 is necessary for human immunodeficiency virus-1 Nef-mediated enhancement of viral gene expression and replication. J. Biol. Chem. 2005, 280(48). 40041-50 Epub 2005 Sept 21.
35. Lee J.J., Seah J.B., Chow V.T., Poh C.L., Tan E.L. Comparative proteome analyses of host protein expression in response to Enterovirus 71 and Coxsackievirus A16 infections. J. Proteomics 2011.
36. Lee J.W., Liu P.F., Hsu L.P., Chen P.R., Chang C.H., Shih W.L. EBV LMP-1 negatively regulates expression and pro-apoptotic activity of Par-4 in nasopharyngeal carcinoma cells. Cancer Lett. 2009, 279(2):193-201.
37. Li R., Xi Y., Liu X., Chen G., Wang B., Jiang L., Li W. Expression of IL-1alpha, IL-6, TGF-beta, FasL and ZNF265 during sertoli cell infection by Ureaplasma urealyticum. Cell Mol. Immunol. 2009, 6(3):215-221.
38. Lin B.Y., Makhov A.M., Griffith J.D., Broker T.R., Chow L.T. Chaperone proteins abrogate inhibition of the human papillomavirus (HPV) E1 replicative helicase by the HPV E2 protein. Mol. Cell. Biol. 2002, 22(18):6592-6604.
39. Liu J., Chen I., Du Q., Chua H., Kwang J. The ORF3 protein of porcine circovirus type 2 is involved in viral pathogenesis in vivo. J. Virol. 2006, 80(10):5065-5073.
40. Liu J., Chen I., Kwang J. Characterization of a previously unidentified viral protein in porcine circovirus type 2-infected cells and its role in virus-induced apoptosis. J. Virol. 2005, 79(13):8262-8274.
41. Liu J., Zhu Y., Chen I., Lau J., He F., Lau A., Wang Z., Karuppannan A.K., Kwang J. The ORF3 protein of porcine circovirus type 2 interacts with porcine ubiquitin E3 ligase Pirh2 and facilitates p53 expression in viral infection. J. Virol. 2007, 81(17):9560-9567.
42. Mankertz A., Domingo M., Folch J.M., LeCann P., Jestin A., Segales J., Chmielewicz B., Plana-Duran J., Soike D. Characterisation of PCV-2 isolates from Spain, Germany and France. Virus Res. 2000, 66(1):65-77.
43. Mankertz A., Hillenbrand B. Analysis of transcription of porcine circovirus type 1. J. Gen. Virol. 2002, 83(Pt 11):2743-2751.
44. Mankertz A., Mankertz J., Wolf K., Buhk H.J. Identification of a protein essential for replication of porcine circovirus. J. Gen. Virol. 1998, 79(Pt 2):381-384.
45. Matthews D.A., Russell W.C. Adenovirus core protein V interacts with p32 - a protein which is associated with both the mitochondria and the nucleus. J. Gen. Virol. 1998, 79(Pt 7):1677-1685.
46. McCloskey R., Menges C., Friedman A., Patel D., McCance D.J. Human papillomavirus type 16 E6/E7 upregulation of nucleophosmin is important for proliferation and inhibition of differentiation. J. Virol. 2010, 84(10):5131-5139.
47. Meehan B.M., Creelan J.L., McNulty M.S., Todd D. Sequence of porcine circovirus DNA: affinities with plant circoviruses. J. Gen. Virol. 1997, 78(Pt 1):221-227.
48. Nawagitgul P., Morozov I., Bolin S.R., Harms P.A., Sorden S.D., Paul P.S. Open reading frame 2 of porcine circovirus type 2 encodes a major capsid protein. J. Gen. Virol. 2000, 81(Pt 9):2281-2287.
49. Neddermann P., Gallinari P., Lettieri T., Schmid D., Truong O., Hsuan J.J., Wiebauer K., Jiricny J. Cloning and expression of human G/T mismatch-specific thymine-DNA glycosylase. J. Biol. Chem. 1996, 271(22):12767-12774.
50. Nyborg J.K., Egan D., Sharma N. The HTLV-1 Tax protein: revealing mechanisms of transcriptional activation through histone acetylation and nucleosome disassembly. Biochim. Biophys. Acta 2010, 1799(3-4):266-274.
51. Oduber C.E., van der Horst C.M., Hennekam R.C. Klippel-Trenaunay syndrome: diagnostic criteria and hypothesis on etiology. Ann. Plast. Surg. 2008, 60(2):217-223.
52. Ramamoorthy S., Huang F.F., Huang Y.W., Meng X.J. Interferon-mediated enhancement of in vitro replication of porcine circovirus type 2 is influenced by an interferon-stimulated response element in the PCV2 genome. Virus Res. 2009, 145(2):236-243.
53. Ramamoorthy S., Opriessnig T., Pal N., Huang F.F., Meng X.J. Effect of an interferon-stimulated response element (ISRE) mutant of porcine circovirus type 2 (PCV2) on PCV2-induced pathological lesions in a porcine reproductive and respiratory syndrome virus (PRRSV) co-infection model. Vet. Microbiol. 2011, 147(1-2):49-58.
54. Ramirez-Boo M., Nunez E., Jorge I., Navarro P., Fernandes L.T., Segales J., Garrido J.J., Vazquez J., Moreno A. Quantitative proteomics by 2-DE, (16) O/(18) O labelling and linear ion trap mass spectrometry analysis of lymph nodes from piglets inoculated by porcine circovirus type 2. Proteomics 2011.
55. Rawat P., Mitra D. Cellular heat shock factor 1 positively regulates human immunodeficiency virus-1 gene expression and replication by two distinct pathways. Nucleic Acids Res. 2011, 39(14):5879-5892.
56. Sarek G., Jarviluoma A., Moore H.M., Tojkander S., Vartia S., Biberfeld P., Laiho M., Ojala P.M. Nucleophosmin phosphorylation by v-cyclin-CDK6 controls KSHV latency. PLoS Pathog. 2010, 6(3):e1000818.
57. Savkur R.S., Olson M.O. Preferential cleavage in pre-ribosomal RNA byprotein B23 endoribonuclease. Nucleic Acids Res. 1998, 26(19):4508-4515.
58. Sells S.F., Wood D.P., Joshi-Barve S.S., Muthukumar S., Jacob R.J., Crist S.A., Humphreys S., Rangnekar V.M. Commonality of the gene programs induced by effectors of apoptosis in androgen-dependent and -independent prostate cells. Cell Growth Differ. 1994, 5(4):457-466.
59. Sharma N., Nyborg J.K. The coactivators CBP/p300 and the histone chaperone NAP1 promote transcription-independent nucleosome eviction at the HTLV-1 promoter. Proc. Natl. Acad. Sci. U.S.A. 2008, 105(23):7959-7963.
60. Sohn S.Y., Kim S.B., Kim J., Ahn B.Y. Negative regulation of hepatitis B virus replication by cellular Hsp40/DnaJ proteins through destabilization of viral core and X proteins. J. Gen. Virol. 2006, 87(Pt 7):1883-1891.
61. Steinfeldt T., Finsterbusch T., Mankertz A. Demonstration of nicking/joining activity at the origin of DNA replication associated with the rep and rep' proteins of porcine circovirus type 1. J. Virol. 2006, 80(13):6225-6234.
62. Szebeni A., Olson M.O. Nucleolar protein B23 has molecular chaperone activities. Protein Sci. 1999, 8(4):905-912.
63. Timmusk S., Fossum C., Berg M. Porcine circovirus type 2 replicase binds the capsid protein and an intermediate filament-like protein. J. Gen. Virol. 2006, 87(Pt 11):3215-3223.
64. Timmusk S., Merlot E., Lovgren T., Jarvekulg L., Berg M., Fossum C. Regulator of G protein signalling 16 is a target for a porcine circovirus type 2 protein. J. Gen. Virol. 2009, 90(Pt 10):2425-2436.
65. Tini M., Benecke A., Um S.J., Torchia J., Evans R.M., Chambon P. Association of CBP/p300 acetylase and thymine DNA glycosylase links DNA repair and transcription. Mol. Cell 2002, 9(2):265-277.
66. Tischer I., Mields W., Wolff D., Vagt M., Griem W. Studies on epidemiology and pathogenicity of porcine circovirus. Arch. Virol. 1986, 91(3-4):271-276.
67. Vetterkind S., Morgan K.G. The pro-apoptotic protein Par-4 facilitates vascular contractility by cytoskeletal targeting of Zipk. J. Cell. Mol. Med. 2008, 24:24.
68. Wakayama Y., Matsuzaki Y., Yamashita S., Inoue M., Jimi T., Hara H., Unaki A., Iijima S., Masaki H. Dysbindin, syncoilin, and beta-synemin mRNA levels in dystrophic muscles. Int. J. Neurosci. 2010, 120(2):144-149.
69. Wang S., Frappier L. Nucleosome assembly proteins bind to Epstein-Barr virus nuclear antigen 1 and affect its functions in DNA replication and transcriptional activation. J. Virol. 2009, 83(22):11704-11714.
70. Watthanasurorot A., Jiravanichpaisal P., Soderhall I., Soderhall K. A gC1qR prevents white spot syndrome virus replication in the freshwater crayfish Pacifastacus leniusculus. J. Virol. 2010, 84(20):10844-10851.
71. Wei L., Kwang J., Wang J., Shi L., Yang B., Li Y., Liu J. Porcine circovirus type 2 induces the activation of nuclear factor kappa B by IkappaBalpha degradation. Virology 2008, 378(1):177-184.
72. Wikstrom F.H., Meehan B.M., Berg M., Timmusk S., Elving J., Fuxler L., Magnusson M., Allan G.M., McNeilly F., Fossum C. Structure-dependent modulation of alpha interferon production by porcine circovirus 2 oligodeoxyribonucleotide and CpG DNAs in porcine peripheral blood mononuclear cells. J. Virol. 2007, 81(10):4919-4927.
73. Xu L., Xiao N., Liu F., Ren H., Gu J. Inhibition of RIG-I and MDA5-dependent antiviral response by gC1qR at mitochondria. Proc. Natl. Acad. Sci. U.S.A. 2009, 106(5):1530-1535.
74. Yi Z., Sperzel L., Nurnberger C., Bredenbeek P.J., Lubick K.J., Best S.M., Stoyanov C.T., Law L.M., Yuan Z., Rice C.M., MacDonald M.R. Identification and characterization of the host protein DNAJC14 as a broadly active flavivirus replication modulator. PLoS Pathog. 2011, 7(1):e1001255.
75. Zhang X., Zhou J., Wu Y., Zheng X., Ma G., Wang Z., Jin Y., He J., Yan Y. Differential proteome analysis of host cells infected with porcine circovirus type 2. J. Proteome Res. 2009, 8(11):5111-5119.
76. Zhang Y., Ma C.J., Ni L., Zhang C.L., Wu X.Y., Kumaraguru U., Li C.F., Moorman J.P., Yao Z.Q. Cross-talk between programmed death-1 and suppressor of cytokine signaling-1 in inhibition of IL-12 production by monocytes/macrophages in hepatitis C virus infection. J. Immunol. 2011, 186(5):3093-3103.