Porcine circovirus type 2 replicase binds the capsid protein and an intermediate filament-like protein

Journal of General Virology

Volumn 87, Issue 11, 2006, Pages 3215-3223

  Timmusk, Sirje ^a   Fossum, Caroline ^a   Berg, Mikael ^a  

^a SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

CAPSID PROTEIN; GLUTATHIONE; MYC PROTEIN; REPLICASE; UNCLASSIFIED DRUG; VIRUS ENZYME;

ANIMAL CELL; ARTICLE; CIRCOVIRIDAE; CONTROLLED STUDY; ENZYME BINDING; LIFE CYCLE; MOLECULAR MECHANICS; NONHUMAN; OPEN READING FRAME; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; SWINE; TWO HYBRID SYSTEM; VIRUS TYPING;

AMINO ACID SEQUENCE; ANIMALS; CAPSID; CAPSID PROTEINS; CELL LINE; CIRCOVIRIDAE INFECTIONS; CIRCOVIRUS; DNA-DIRECTED DNA POLYMERASE; INTERMEDIATE FILAMENT PROTEINS; MOLECULAR SEQUENCE DATA; OPEN READING FRAMES; PROTEIN BINDING; SEQUENCE ALIGNMENT; SWINE; TWO-HYBRID SYSTEM TECHNIQUES; VIRAL PROTEINS; VIRUS REPLICATION;

BACTERIA (MICROORGANISMS); MIRIDAE; PORCINE CIRCOVIRUS 2; SUIDAE;

EID: 33750267397     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/vir.0.81785-0     Document Type: Article

References (41)

1. Allan, G. M. & Ellis, J. A. (2000). Porcine circoviruses: a review. J Vet Diagn Invest 12, 3-14.
2. Beadling, C., Druey, K. M., Richter, G., Kehrl, J. H. & Smith, K. A. (1999). Regulators of G protein signaling exhibit distinct patterns of gene expression and target G protein specificity in human lymphocytes. J Immunol 162, 2677-2682.
3. Berg, M. & Stenlund, A. (1997). Functional interactions between papillomavirus E1 and E2 proteins. J Virol 71, 3853-3863.
4. Berg, M., Ehrenborg, C., Blomberg, J., Pipkorn, R. & Berg, A. L. (1998). Two domains of the Borna disease virus p40 protein are required for interaction with the p23 protein. J Gen Virol 79, 2957-2963.
5. Berthebaud, M., Riviera, C., Jarrier, P., Foudi, A., Zhang, Y., Compagno, D., Galy, A., Vainchenker, W. & Louache, F. (2005). RGS16 is a negative regulator of SDF-1-CXCR4 signaling in megakaryocytes. Blood 106, 2962-2968.
6. Briddon, R. W., Watts, J., Markham, P. G. & Stanley, J. (1989). The coat protein of beet curly top virus is essential for infectivity. Virology 172, 628-633.
7. Cheung, A. K. (2003a). Comparative analysis of the transcriptional patterns of pathogenic and nonpathogenic porcine circoviruses. Virology 310, 41-49.
8. Cheung, A. K. (2003b). The essential and nonessential transcription units for viral protein synthesis and DNA replication of porcine circovirus type 2. Virology 313, 452-459.
9. Cheung, A. K. & Bolin, S. R. (2002). Kinetics of porcine circovirus type 2 replication. Arch Virol 147, 43-58.
10. Clark, E. G. (1997). Post-weaning multisystemic wasting syndrome. Proc Am Assoc Swine Pract 28, 499-501.
11. Crowther, R. A., Berriman, J. A., Curran, W. L., Allan, G. M. & Todd, D. (2003). Comparison of the structures of three circoviruses: chicken anemia virus, porcine circovirus type 2, and beak and feather disease virus. J Virol 77, 13036-13041.
12. Finsterbusch, T., Steinfeldt T., Caliskan, R. & Mankertz, A. (2005). Analysis of the subcellular localization of the proteins Rep, Rep' and Cap of porcine circovirus type 1. Virology 343, 36-46.
13. Gibbs, M. J. & Weiller, G. F. (1999). Evidence that a plant virus switched hosts to infect a vertebrate and then recombined with a vertebrate-infecting virus. Proc Natl Acad Sci U S A 96, 8022-8027.
14. Gilpin, D. F., McCullough, K., Meehan, B. M. & 8 other authors (2003). In vitro studies on the infection and replication of porcine circovirus type 2 in cells of the porcine immune system. Vet Immunol Immunopathol 94, 149-161.
15. Harding, J. C. & Clark, E. G. (1997). Recognizing and diagnosing postweaning multisystemic wasting syndrome (PMWS). Swine Health Prod 5, 201-204.
16. Hartig, R., Shoeman, R. L., Janetzko, A., Tolstonog, G. & Traub, P. (1998). DNA-mediated transport of the intermediate filament protein vimentin into the nucleus of cultured cells. J Cell Sci 111, 3573-3584.
17. Kawabata, K, Ujikawa, M., Egawa, T., Kawamoto, H., Tachibana, K., Iizasa, H., Katsura, Y., Kishimoto, T. & Nagasawa, T. (1999). A cell-autonomous requirement for CXCR4 in long-term lymphoid and myeloid reconstitution. Proc Natl Acad Sci U S A 96, 5663-5667.
18. Lapham, A. S., Phillips, E. S. & Barton, C. H. (2004). Transcriptional control of Nrampl: a paradigm for the repressive action of c-myc. Biochem Soc Trans 32, 1084-1086.
19. Lippert, E., Yowe, D. L., Gonzalo, J. A. & 9 other authors (2003). Role of regulator of G protein signaling 16 in inflammation-induced T lymphocyte migration and activation. J Immunol 171, 1542-1555.
20. Liu, O., Willson, P., Attoh-Poku, S. & Babiuk, L. A. (2001). Bacterial expression of an immunologically reactive PCV2 ORF2 fusion protein. Protein Expr Purif 21, 115-120.
21. Liu, J., Chen, I. & Kwang, J. (2005). Characterization of a previously unidentified viral protein in porcine circovirus type 2-infected cells and its role in virus-induced apoptosis. J Virol 79, 8262-8274.
22. Mankertz, A., Persson, F., Mankertz, J., Blaess, G. & Buhk, H. J. (1997). Mapping and characterization of the origin of DNA replication of porcine circovirus. J Virol 71, 2562-2566.
23. Mankertz, A., Mueller, B., Steinfeldt, T., Schmitt, C. & Finsterbusch, T. (2003). New reporter gene-based replication assay reveals exchangeability of replication factors of porcine circovirus types 1 and 2. J Virol 77, 9885-9893.
24. Meehan, B. M., McNeilly, F., Todd, D. & 7 other authors (1998). Characterization of novel circovirus DNAs associated with wasting syndromes in pigs. J Gen Virol 79, 2171-2179.
25. Navratil, J. S., Watkins, S. C., Wisnieski, J. J. & Ahearn, J. M. (2001). The globular heads of C1q specifically recognize surface blebs of apoptotic vascular endothelial cells. J Immunol 166, 3231-3239.
26. Nawagitgul, P., Morozov, I., Bolin, S. R., Harms, P. A., Sorden, S. D. & Paul, P. S. (2000). Open reading frame 2 of porcine circovirus type 2 encodes a major capsid protein. J Gen Virol 81, 2281-2287.
27. Newey, S. E., Howman, E. V., Ponting, C. P, Benson, M. A., Nawrotzki, R., Loh, N. Y., Davies, K. E. & Blake, D. J. (2001). Syncoilin, a novel member of the intermediate filament superfamily that interacts with alpha-dystrobrevin in skeletal muscle. J Biol Chem 276, 6645-6655.
28. Padidam, M., Beachy, R. N. & Fauquet, C. M. (1999). A phage single-stranded DNA (ssDNA) binding protein complements ssDNA accumulation of a geminivirus and interferes with viral movement. J Virol 73, 1609-1616.
29. Poon, E., Howman, E. V., Newey, S. E. & Davies, K E. (2002). Association of syncoilin and desmin: linking intermediate filament proteins to the dystrophin-associated protein complex. J Biol Chem 277, 3433-3439.
30. Pringle, C. R. (1999). Virus taxonomy - 1999. The universal system of virus taxonomy, updated to include the new proposals ratified by the International Committee on Taxonomy of Viruses during 1998. Arch Virol 144, 421-429.
31. Qin, S., Ward, B. M. & Lazarowitz, S. G. (1998). The bipartite geminivirus coat protein aids BR1 function in viral movement by affecting the accumulation of viral single-stranded DNA. J Virol 72, 9247-9256.
32. Sambrook J. & Russell, D. (2001). Molecular Cloning: a Laboratory Manual, 3rd edn. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory.
33. Sarria, A. J., Lieber, J. G., Nordeen, S. K. & Evans, R. M. (1994). The presence or absence of a vimentin-type intermediate filament network affects the shape of the nucleus in human SW-13 cells. J Cell Sci 107, 1593-1607.
34. Smith, G. A. & Enquist, L. W. (2002). Break ins and break outs: viral interactions with the cytoskeleton of mammalian cells. Annu Rev Cell Dev Biol 18, 135-161.
35. Sodeik, B., Ebersold, M. W. & Helenius, A. (1997). Microtubulemediated transport of incoming herpes simplex virus 1 capsids to the nucleus. J Cell Biol 136, 1007-1021.
36. Steinfeldt, T., Finsterbusch, T. & Mankertz, A. (2001). Rep and Rep' protein of porcine circovirus type 1 bind to the origin of replication in vitro. Virology 291, 152-160.
37. Suikkanen, S., Aaltonen, T., Nevalainen, M., Välilehto, O., Lindholm, L., Vuento, M. & Vihinen-Ranta, M. (2003). Exploitation of microtubule cytoskeleton and dynein during parvoviral traffic towards the nucleus. J Virol 77, 10270-10279.
38. Tischer, I., Gelderblom, H., Vettermann, W. & Koch, M. A. (1982). A very small porcine virus with circular single-stranded DNA. Nature 295, 64-66.
39. Todd, D., Creelan, J. L. & McNulty, M. S. (1991). Dot blot hybridization assay for chicken anemia agent using a cloned DNA probe. J Clin Microbiol 29, 933-939.
40. Vincent I. E, Carrasco, C. P., Herrmann, B., Meehan, B. M., Allan, G. M. Summerfield, A. & McCullough, K. C. (2003). Dendritic cells harbor infectious porcine circovirus type 2 in the absence of apparent cell modulation or replication of the virus. J Virol 77, 13288-13300.
41. Xie, Q, Suarez-Lopez, P. & Gutierrez, C. (1995). Identification and analysis of a retinoblastoma binding motif in the replication protein of a plant DNA virus: requirement for efficient viral DNA replication. EMBO J 14, 4073-4082.