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Volumn 279, Issue 2, 2009, Pages 193-201

EBV LMP-1 negatively regulates expression and pro-apoptotic activity of Par-4 in nasopharyngeal carcinoma cells

Author keywords

EBV; LMP 1; Nasopharyngeal carcinoma; Par 4

Indexed keywords

LATENT MEMBRANE PROTEIN 1; PROSTATE APOPTOSIS RESPONSE 4 PROTEIN; PROTEIN; PROTEIN BCL 2; UNCLASSIFIED DRUG;

EID: 67349178306     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2009.01.037     Document Type: Article
Times cited : (14)

References (48)
  • 1
    • 0027818316 scopus 로고
    • Etiology of nasopharyngeal carcinoma: a review
    • Hildesheim A., and Levine P.H. Etiology of nasopharyngeal carcinoma: a review. Epidemiol. Rev. 15 (1993) 466-485
    • (1993) Epidemiol. Rev. , vol.15 , pp. 466-485
    • Hildesheim, A.1    Levine, P.H.2
  • 2
    • 33846705453 scopus 로고    scopus 로고
    • Nasopharyngeal carcinoma: molecular biomarker discovery and progress
    • Cho W.C. Nasopharyngeal carcinoma: molecular biomarker discovery and progress. Mol. Cancer 6 (2007) 1-9
    • (2007) Mol. Cancer , vol.6 , pp. 1-9
    • Cho, W.C.1
  • 3
    • 0000942112 scopus 로고    scopus 로고
    • Knipe D.M., and Howley P.M. (Eds), Lippincott Williams & Wilkins, Philadelphia
    • Rickinson A.B., and Kief E. Fields' Virology. In: Knipe D.M., and Howley P.M. (Eds) (2001), Lippincott Williams & Wilkins, Philadelphia 2575-2627
    • (2001) Fields' Virology , pp. 2575-2627
    • Rickinson, A.B.1    Kief, E.2
  • 4
    • 0036435166 scopus 로고    scopus 로고
    • Epstein-Barr virus in the pathogenesis of NPC
    • Raab-Traub N. Epstein-Barr virus in the pathogenesis of NPC. Semin. Cancer Biol. 12 (2002) 431-441
    • (2002) Semin. Cancer Biol. , vol.12 , pp. 431-441
    • Raab-Traub, N.1
  • 6
    • 0022309824 scopus 로고
    • An EBV membrane protein expressed in immortalized lymphocytes transforms established rodent cells
    • Wang D., Liebowitz D., and Kieff E. An EBV membrane protein expressed in immortalized lymphocytes transforms established rodent cells. Cell 43 (1985) 831-840
    • (1985) Cell , vol.43 , pp. 831-840
    • Wang, D.1    Liebowitz, D.2    Kieff, E.3
  • 7
    • 0027449255 scopus 로고
    • Epstein-Barr virus latent membrane protein 1 is essential for B-lymphocyte growth transformation
    • Kaye K.M., Izumi K.M., and Kieff E. Epstein-Barr virus latent membrane protein 1 is essential for B-lymphocyte growth transformation. Proc. Natl. Acad. Sci. USA 90 (1993) 9150-9154
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 9150-9154
    • Kaye, K.M.1    Izumi, K.M.2    Kieff, E.3
  • 8
    • 0025325549 scopus 로고
    • Morphological transformation of human keratinocytes expressing the LMP gene of Epstein-Barr virus
    • Fahraeus R., Rymo L., Rhim J.S., and Klein G. Morphological transformation of human keratinocytes expressing the LMP gene of Epstein-Barr virus. Nature 345 (1990) 447-449
    • (1990) Nature , vol.345 , pp. 447-449
    • Fahraeus, R.1    Rymo, L.2    Rhim, J.S.3    Klein, G.4
  • 9
    • 35148887346 scopus 로고    scopus 로고
    • Protein expression and intracellular localization of prostate apoptosis response-4 (Par-4) are associated with apoptosis induction in nasopharyngeal carcinoma cell lines
    • Lee J.W., Lee K.F., Hsu H.Y., Hsu L.P., Shih W.L., Chu Y.C., Hsiao W.T., and Liu P.F. Protein expression and intracellular localization of prostate apoptosis response-4 (Par-4) are associated with apoptosis induction in nasopharyngeal carcinoma cell lines. Cancer Lett. 257 (2007) 252-262
    • (2007) Cancer Lett. , vol.257 , pp. 252-262
    • Lee, J.W.1    Lee, K.F.2    Hsu, H.Y.3    Hsu, L.P.4    Shih, W.L.5    Chu, Y.C.6    Hsiao, W.T.7    Liu, P.F.8
  • 11
    • 0037328539 scopus 로고    scopus 로고
    • Apoptosis by Par-4 in cancer and neurodegenerative diseases
    • El-Guendy N., and Rangnekar V.M. Apoptosis by Par-4 in cancer and neurodegenerative diseases. Exp. Cell Res. 283 (2003) 51-66
    • (2003) Exp. Cell Res. , vol.283 , pp. 51-66
    • El-Guendy, N.1    Rangnekar, V.M.2
  • 12
    • 12844253808 scopus 로고    scopus 로고
    • Phosphorylation of Par-4 by protein kinase A is critical for apoptosis
    • Gurumurthy S., Goswami A., Vasudevan K.M., and Rangnekar V.M. Phosphorylation of Par-4 by protein kinase A is critical for apoptosis. Mol. Cell Biol. 25 (2005) 1146-1161
    • (2005) Mol. Cell Biol. , vol.25 , pp. 1146-1161
    • Gurumurthy, S.1    Goswami, A.2    Vasudevan, K.M.3    Rangnekar, V.M.4
  • 14
    • 0030572696 scopus 로고    scopus 로고
    • The product of par-4, a gene induced during apoptosis, interacts selectively with the atypical isoforms of protein kinase C
    • Diaz-Meco M.T., Municio M.M., Frutos S., Sanchez P., Lozano J., Sanz L., and Moscat J. The product of par-4, a gene induced during apoptosis, interacts selectively with the atypical isoforms of protein kinase C. Cell 86 1996 (1996) 777-786
    • (1996) Cell , vol.86 , Issue.1996 , pp. 777-786
    • Diaz-Meco, M.T.1    Municio, M.M.2    Frutos, S.3    Sanchez, P.4    Lozano, J.5    Sanz, L.6    Moscat, J.7
  • 16
    • 0033518129 scopus 로고    scopus 로고
    • Interaction partners of Dlk/ZIP kinase: co-expression of Dlk/ZIP kinase and Par-4 results in cytoplasmic retention and apoptosis
    • Page G., Kögel D., Rangnekar V., and Scheidtmann K.H. Interaction partners of Dlk/ZIP kinase: co-expression of Dlk/ZIP kinase and Par-4 results in cytoplasmic retention and apoptosis. Oncogene 18 (1999) 7265-7273
    • (1999) Oncogene , vol.18 , pp. 7265-7273
    • Page, G.1    Kögel, D.2    Rangnekar, V.3    Scheidtmann, K.H.4
  • 17
    • 27744512031 scopus 로고    scopus 로고
    • Par-4-mediated recruitment of Amida to the actin cytoskeleton leads to the induction of apoptosis
    • Boosen M., Vetterkind S., Koplin A., Illenberger S., and Preuss U. Par-4-mediated recruitment of Amida to the actin cytoskeleton leads to the induction of apoptosis. Exp. Cell Res. 311 (2005) 177-191
    • (2005) Exp. Cell Res. , vol.311 , pp. 177-191
    • Boosen, M.1    Vetterkind, S.2    Koplin, A.3    Illenberger, S.4    Preuss, U.5
  • 19
    • 0035477544 scopus 로고    scopus 로고
    • Par-4 drives trafficking and activation of Fas and FasL to induce prostate cancer cell apoptosis and tumor regression
    • Chakraborty M., Qiu S.G., Vasudevan K.M., and Rangnekar V.M. Par-4 drives trafficking and activation of Fas and FasL to induce prostate cancer cell apoptosis and tumor regression. Cancer Res. 61 (2001) 7255-7263
    • (2001) Cancer Res. , vol.61 , pp. 7255-7263
    • Chakraborty, M.1    Qiu, S.G.2    Vasudevan, K.M.3    Rangnekar, V.M.4
  • 20
    • 0043133881 scopus 로고    scopus 로고
    • Identification of a unique core domain of Par-4 sufficient for selective apoptosis induction in cancer cells
    • El-Guendy N., Zhao Y., Gurumurthy S., Burikhanov R., and Rangnekar V.M. Identification of a unique core domain of Par-4 sufficient for selective apoptosis induction in cancer cells. Mol. Cell Biol. 23 (2003) 5516-5525
    • (2003) Mol. Cell Biol. , vol.23 , pp. 5516-5525
    • El-Guendy, N.1    Zhao, Y.2    Gurumurthy, S.3    Burikhanov, R.4    Rangnekar, V.M.5
  • 21
    • 20744447485 scopus 로고    scopus 로고
    • Ras-mediated loss of the pro-apoptotic response protein Par-4 is mediated by DNA hypermethylation through Raf-independent and Raf-dependent signaling cascades in epithelial cells
    • Pruitt K., Ülkü A.S., Frantz K., Rojas R.J., Muniz-Medina V.M., Rangnekar V.M., Der C.J., and Shields J.M. Ras-mediated loss of the pro-apoptotic response protein Par-4 is mediated by DNA hypermethylation through Raf-independent and Raf-dependent signaling cascades in epithelial cells. J. Biol. Chem. 280 (2005) 23363-23370
    • (2005) J. Biol. Chem. , vol.280 , pp. 23363-23370
    • Pruitt, K.1    Ülkü, A.S.2    Frantz, K.3    Rojas, R.J.4    Muniz-Medina, V.M.5    Rangnekar, V.M.6    Der, C.J.7    Shields, J.M.8
  • 23
    • 0033604464 scopus 로고    scopus 로고
    • Negative regulation of Par-4 by oncogenic Ras is essential for cellular transformation
    • Qiu S.G., Krishnan S., El-Guendy N., and Rangnekar V.M. Negative regulation of Par-4 by oncogenic Ras is essential for cellular transformation. Oncogene 18 (1999) 7115-7123
    • (1999) Oncogene , vol.18 , pp. 7115-7123
    • Qiu, S.G.1    Krishnan, S.2    El-Guendy, N.3    Rangnekar, V.M.4
  • 25
    • 0033570912 scopus 로고    scopus 로고
    • The downregulation of the pro-apoptotic protein Par-4 is critical for Ras-induced survival and tumor progression
    • Barradas M., Monjas A., Diaz-Meco M.T., Serrano M., and Moscat J. The downregulation of the pro-apoptotic protein Par-4 is critical for Ras-induced survival and tumor progression. EMBO J. 18 (1999) 6362-6369
    • (1999) EMBO J. , vol.18 , pp. 6362-6369
    • Barradas, M.1    Monjas, A.2    Diaz-Meco, M.T.3    Serrano, M.4    Moscat, J.5
  • 26
    • 0242585506 scopus 로고    scopus 로고
    • Genetic inactivation of Par-4 results in hyperactivation of NF-κB and impairment of JNK and p38
    • Garcia-Cao I., Lafuente M.J., Criado L.M., Diaz-Meco M.T., Serrano M., and Moscat J. Genetic inactivation of Par-4 results in hyperactivation of NF-κB and impairment of JNK and p38. EMBO Rep. 4 (2003) 307-312
    • (2003) EMBO Rep. , vol.4 , pp. 307-312
    • Garcia-Cao, I.1    Lafuente, M.J.2    Criado, L.M.3    Diaz-Meco, M.T.4    Serrano, M.5    Moscat, J.6
  • 28
    • 33645733587 scopus 로고    scopus 로고
    • Targeted ablation of Par-4 reveals a cell type-specific susceptibility to apoptosis-inducing agents
    • Affar El.B., Luke M.P., Gay F., Calvo D., Sui G., Weiss R.S., Li E., and Shi Y. Targeted ablation of Par-4 reveals a cell type-specific susceptibility to apoptosis-inducing agents. Cancer Res. 66 (2006) 3456-3462
    • (2006) Cancer Res. , vol.66 , pp. 3456-3462
    • Affar, El.B.1    Luke, M.P.2    Gay, F.3    Calvo, D.4    Sui, G.5    Weiss, R.S.6    Li, E.7    Shi, Y.8
  • 32
    • 3843127864 scopus 로고    scopus 로고
    • Par-4 inducible apoptosis in prostate cancer cells
    • Gurumurthy S., and Rangnekar V.M. Par-4 inducible apoptosis in prostate cancer cells. J. Cell Biochem. 91 (2004) 504-512
    • (2004) J. Cell Biochem. , vol.91 , pp. 504-512
    • Gurumurthy, S.1    Rangnekar, V.M.2
  • 33
    • 0032824654 scopus 로고    scopus 로고
    • Requirement for cell-to-cell contact in Epstein-Barr virus infection of nasopharyngeal carcinoma cells and keratinocytes
    • Chang Y., Tung C.H., Huang Y.T., Lu J., Chen J.Y., Tsai, and Tsai C.H. Requirement for cell-to-cell contact in Epstein-Barr virus infection of nasopharyngeal carcinoma cells and keratinocytes. J. Virol. 73 (1999) 8857-8866
    • (1999) J. Virol. , vol.73 , pp. 8857-8866
    • Chang, Y.1    Tung, C.H.2    Huang, Y.T.3    Lu, J.4    Chen, J.Y.5    Tsai6    Tsai, C.H.7
  • 35
    • 0008881181 scopus 로고    scopus 로고
    • Mutually exclusive expression patterns of Bcl-2 and Par-4 in human prostate tumors consistent with down-regulation of Bcl-2 by Par-4
    • Qiu G., Ahmed M., Sells S.F., Mohiuddin M., Weinstein M.H., and Rangnekar V.M. Mutually exclusive expression patterns of Bcl-2 and Par-4 in human prostate tumors consistent with down-regulation of Bcl-2 by Par-4. Oncogene 18 (1999) 623-631
    • (1999) Oncogene , vol.18 , pp. 623-631
    • Qiu, G.1    Ahmed, M.2    Sells, S.F.3    Mohiuddin, M.4    Weinstein, M.H.5    Rangnekar, V.M.6
  • 36
    • 0035022291 scopus 로고    scopus 로고
    • Deregulated expression of prostate apoptosis response gene-4 in less differentiated lymphocytes and inverse expressional patterns of par-4 and bcl-2 in acute lymphocytic leukemia
    • Boehrer S., Chow K.U., Puccetti E., Ruthardt M., Godzisard S., Krapohl A., Schneider B., Hoelzer D., Mitrou P.S., Rangnekar V.M., and Weidmann E. Deregulated expression of prostate apoptosis response gene-4 in less differentiated lymphocytes and inverse expressional patterns of par-4 and bcl-2 in acute lymphocytic leukemia. Hematol. J. 2 (2001) 103-107
    • (2001) Hematol. J. , vol.2 , pp. 103-107
    • Boehrer, S.1    Chow, K.U.2    Puccetti, E.3    Ruthardt, M.4    Godzisard, S.5    Krapohl, A.6    Schneider, B.7    Hoelzer, D.8    Mitrou, P.S.9    Rangnekar, V.M.10    Weidmann, E.11
  • 39
    • 2342489456 scopus 로고    scopus 로고
    • eIF-4E expression and its role in malignancies and metastases
    • De Benedetti A., and Graff J.R. eIF-4E expression and its role in malignancies and metastases. Oncogene 23 (2004) 3189-3199
    • (2004) Oncogene , vol.23 , pp. 3189-3199
    • De Benedetti, A.1    Graff, J.R.2
  • 41
    • 8644230153 scopus 로고    scopus 로고
    • Induction of Epstein-Barr virus latent membrane protein 1 by a lytic transactivator Rta
    • Chang Y., Lee H.H., Chang S.S., Hsu T.Y., Wang P.W., Cahng Y.S., Takada K., and Tsai C.H. Induction of Epstein-Barr virus latent membrane protein 1 by a lytic transactivator Rta. J. Virol. 78 (2004) 13028-13036
    • (2004) J. Virol. , vol.78 , pp. 13028-13036
    • Chang, Y.1    Lee, H.H.2    Chang, S.S.3    Hsu, T.Y.4    Wang, P.W.5    Cahng, Y.S.6    Takada, K.7    Tsai, C.H.8
  • 42
    • 0031671342 scopus 로고    scopus 로고
    • Antibody against the Epstein-Barr virus BHRF1 protein, a homologue of Bcl-2, in patients with nasopharyngeal carcinoma
    • Liu M.Y., Y Shih Y., Chou S.P., Chen C.J., Sheen T.S., Yang C.S., and Chen J.Y. Antibody against the Epstein-Barr virus BHRF1 protein, a homologue of Bcl-2, in patients with nasopharyngeal carcinoma. J. Med. Virol. 56 (1998) 179-185
    • (1998) J. Med. Virol. , vol.56 , pp. 179-185
    • Liu, M.Y.1    Y Shih, Y.2    Chou, S.P.3    Chen, C.J.4    Sheen, T.S.5    Yang, C.S.6    Chen, J.Y.7
  • 43
    • 33646926129 scopus 로고    scopus 로고
    • 14-3-3 Proteins: a historic overview
    • Aitken A. 14-3-3 Proteins: a historic overview. Semin. Cancer Biol. 16 (2006) 162-172
    • (2006) Semin. Cancer Biol. , vol.16 , pp. 162-172
    • Aitken, A.1
  • 44
    • 33645524134 scopus 로고    scopus 로고
    • The phosphoinositide 3-kinase/Akt1/Par-4 axis: a cancer-selective therapeutic target
    • Goswami A., Ranganathan P., and Rangnekar V.M. The phosphoinositide 3-kinase/Akt1/Par-4 axis: a cancer-selective therapeutic target. Cancer Res. 66 (2006) 2889-2892
    • (2006) Cancer Res. , vol.66 , pp. 2889-2892
    • Goswami, A.1    Ranganathan, P.2    Rangnekar, V.M.3
  • 47
    • 0037198274 scopus 로고    scopus 로고
    • NF-κB activates Bcl-2 expression in t(14;18) lymphoma cells
    • Heckmen C.A., Mehew J.W., and Boxer L.M. NF-κB activates Bcl-2 expression in t(14;18) lymphoma cells. Oncogene 21 (2002) 3898-3908
    • (2002) Oncogene , vol.21 , pp. 3898-3908
    • Heckmen, C.A.1    Mehew, J.W.2    Boxer, L.M.3


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