Intermedin elicits a negative inotropic effect in rat papillary muscles mediated by endothelial-derived nitric oxide

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 302, Issue 5, 2012, Pages

  Pires, Ana Luísa ^a   Pinho, Marta ^a   Sena, Cristina Maria ^b   Seica, Raquel ^b   Leite Moreira, Adelino F ^a  

^a University of Porto   (Portugal)

^b UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

Adrenomedullin 2; Cardiac endothelial cells; Contractile effect; Myofilament desensitization; Neurohormones; Nitric oxide synthase

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; CALCITONIN GENE RELATED PEPTIDE RECEPTOR; CYCLIC AMP DEPENDENT PROTEIN KINASE; GUANYLATE CYCLASE; INTERMEDIN; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE REDUCTASE; TROPONIN I;

ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DESENSITIZATION; ENDOCARDIUM; ENZYME ACTIVATION; ENZYME INHIBITION; HEART CONTRACTION; HEART FUNCTION; HEART LEFT VENTRICLE; HEART PAPILLARY MUSCLE; HEART PERFORMANCE; INOTROPISM; MICROVASCULAR ENDOTHELIAL CELL; MYOFILAMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; VELOCITY; WESTERN BLOTTING;

ADRENOMEDULLIN; ANIMALS; CALCITONIN GENE-RELATED PEPTIDE; ENDOTHELIUM, VASCULAR; ENZYME INHIBITORS; GUANYLATE CYCLASE; HEART; MICROVESSELS; MUSCLE CONTRACTION; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OXADIAZOLES; PAPILLARY MUSCLES; PEPTIDE FRAGMENTS; QUINOXALINES; RATS; RATS, WISTAR; TROPONIN I;

EID: 84857305638     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00877.2011     Document Type: Article

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