Negative inotropic effect of adrenomedullin in isolated adult rabbit cardiac ventricular myocytes

Circulation

Volumn 95, Issue 9, 1997, Pages 2318-2324

  Ikenouchi, Hiroshi ^b   Kangawa, Kenji ^a   Matsuo, Hisayuki ^a   Hirata, Yasunobu ^c  

^a NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c NONE

Author keywords

adrenomedullin; calcium; contractility; myocytes; nitric oxide

Indexed keywords

8 BROMO CYCLIC GMP; ADRENOMEDULLIN; ARGININE; CALCITONIN GENE RELATED PEPTIDE; COLLAGENASE; CYCLIC AMP; CYCLIC GMP; FORSKOLIN; HYALURONIDASE; N(G) METHYLARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR;

ANIMAL CELL; ARTICLE; AUTOCRINE EFFECT; CALCIUM TRANSPORT; CONTROLLED STUDY; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HEART VENTRICLE WALL; INOTROPISM; NONHUMAN; PRIORITY JOURNAL; RABBIT; SECOND MESSENGER; VASODILATATION;

EID: 0030994735     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.95.9.2318     Document Type: Article

References (31)

1. Kitamura K, Kangawa K, Kawamoto M, Ichiki Y, Nakamura S, Matsuo H, Eto T. Adrenomedullin: a novel hypotensive peptide isolated from human pheochromocytoma. Biochem Biophys Res Commun. 1993;192:553-560.
2. Nishikimi T, Kitamura K, Saito Y, Shimada K, Ishimitsu T, Takamiya M, Kangawa K, Matsuo H, Eto T, Omae T, Matsuoka H. Clinical studies on the sites of production and clearance of circulating adrenomedullin in human subjects. Hypertension, 1994;24: 600-604.
3. Sakata J, Shimokubo T, Kitamura K, Nishizono M, Ichiki Y, Kangawa K, Matsuo H, Eto T. Distribution and characterization of immunoreactive rat adrenomedullin in tissue and plasma. FEBS Lett. 1994;352:105-108.
4. Nuki C, Kawasaki H, Kitamura K, Takenaga M, Kangawa K, Eto T, Wada A. Vasodilator effect of adrenomedullin and calcitonin gene-related peptide receptors in rat mesenteric vascular beds. Biochem Biophys Res Commun. 1993;196:245-251.
5. Kitamura K, Sakata J, Kangawa K, Kojima M, Matsuo H, Eto T. Cloning and characterization of cDNA encoding a precursor for human adrenomedullin. Biochem Biophys Res Commun. 1993;194: 720-725.
6. Ichiki Y, Kitamura K, Kangawa K, Kawamoto M, Matsuo H, Eto T. Distribution and characterization of immunoreactive adrenomedullin in human tissue and plasma. FEBS Lett. 1994; 338:6-10.
7. Owji AA, Smith DM, Coppock HA, Morgan DG, Bhogal R, Ghatei MA, Bloon SR, An abundant and specific binding site for the novel vasodilator adrenomedullin in the rat Endocrinology. 1995;136: 2127-2134.
8. Jougasaki M, Wei C, McKinley LJ, Burnett JC Jr. Elevation of circulating and ventricular adrenomedullin in human congestive heart failure. Circulation. 1995;92:286-289.
9. Perret M, Broussard H, LeGros T, Burns A, Chang JK, Summer W, Hyman A, Lippton H. The effect of adrenomedullin on the isolated heart. Life Sci. 1993;53:PL377-PL379.
10. Hiratu Y, Hayakawa H, Suzuki Y, Suzuki E, Ikenouchi H, Kohmoto O, Kimura K, Kitamura K, Eto T, Kangawa K, Matsuo H, Omata M. Mechanisms of adrenomedullin-induced vasodilation in the rat kidney. Hypertension. 1995;25:790-79.
11. 2+ mobilization, in bovine aortic endothetial cells. J Biol Chem. 1995;270:4412-4417.
12. 2+ current. J Biol Chem. 1993;268:26286-26295.
13. 2+ current is regulated by cyclic GMP-dcpendent protein kinase in mammalian cardiac myocytcs. Proc Natl Acad Sci U S A. 1991;88:1197-1201.
14. Wahler GM, Dollinger S. Nitric oxide donor SIN-1 inhibits mammalian cardiac calcium current through cGMP-decpendent protein kinase. Am J Physiol. 1995;268:C45-C54.
15. Balligand JL, Kobzik L, Man X, Kaye DM, Belhassen L, O'Hara DS, Kelly RA, Smith TW, Michel T. Nitric oxide-dependent parasympathetic signaling is due to activation of constitutive endothelial (type III) nitric oxide synthase in cardiac myocytes. J Biol Chem. 1995;270:14582-14586.
16. Ungureanu-Longrois D, Balligand J-L, Okada I, Simmons WW, Kobzik L, Lowenstein CJ, Kunkel SL, Michel T, Kelly RA, Smith TW. Contractile responsiveness of ventricular myocytes to isoproterenol is regulated by induction of nitric oxide synthase activity in cardiac microvascular endothelial cells in heterotypic primary culture. Circ Res. 1995;77:486-493.
17. Haddad J, Decker ML, Hsieh L, Lesch M, Samarel AM, Docker RS. Attachment and maintenance of adult rabbit cardiac myocytes in primary cell culture. Am J Physiol. 1988;255:C19-C27.
18. i to altered diastolic myocyte tone during partial metabolic inhibition. J Clin Invest. 1991;88:55-61.
19. Peeters GA, Hlady V, Bridge JHB, Barry WH. Simultaneous measurement of calcium transients and motion in cultured heart cells. Am J Physiol. 1987;253:H1400-H1408.
20. Hamill O, Marty E, Neher E, Sakmann B, Sigworth F. Improved patch-clamp techniques for high resolution current recording from cells and cell-free membrane patches. Pflugers Arch. 1981;391: 85-100.
21. Kohmoto O, Levi AJ, Bridge JHB. The relationship between reverse Na-Ca exchange and SR Ca release in guinea pig ventricular cells. Circ Res. 1994;74;550-554.
22. i and contraction in ventricular myocytes. Am J Physiol 1993; 265:H793-H800.
23. 2+ current in rat ventricular myocytes. Circ Res. 1995;77:803-812.
24. 2+ in intact cardiac myocytes. Circ Res. 1994;74:970-978.
25. 2+ and pH in isolated beating rabbit hearts and myocytes loaded with the indicator indo 1. J Physiol (Lond). 1994;480:203-216.
26. Eguchi S, Hirata Y, Kano H, Sato K, Watanabe Y, Watanabe TX, Nakajima K, Sakakibara S, Marumo F. Specific receptors for adrenomedullin in cultured rat vascular smooth muscle cells. FEBS Lett. 1994;340:226-230.
27. Nuki C, Kawasaki H, Kitamura K, Takenaga M, Kangawa K, Eto T, Wada A, Vasodilator effect of adrenomedullin and calcitonin gene-related peptide receptors in rat mesenteric vascular beds. Biochem Biophys Res Commun. 1993;196:245-251.
28. Clancy RM, Leszczynska-Piziak J, Abramson SB. Nitric oxide, an endotheliel cell relaxation factor, inhibits neutrophil superoxide anion production via a direct action on the NADPH oxidase. J Clin Invest. 1992;90:1116-1121.
29. 2+. Cell Calcium. 1991;12:415-422.
30. Ishimitsu T, Nishikimi T, Saito Y, Kitamura K, Eto T, Kangawa K, Matsuo H, Omae T, Matsuoka H. Plasma levels of adrenomedullin, a newly identified hypotensive peptide, in patients with hypertension and renal failure. J Clin Invest. 1994;94:2158-2161.
31. Lefer DJ, Nakanishi K, Vinten-Johansen J, Endothelial and myocardial cell protection by a cysteine-containing nitric oxide donor after myocardial ischemia and reperfusion. J Cardiovasc Pharmacol. 1993;22(suppl 7):s34-s43.