Endothelial cell regulation of contractility of the heart

Annual Review of Physiology

Volumn 59, Issue , 1997, Pages 505-525

  Winegrad, Saul ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

ATPase activity; cardiac myocytes; contractile efficiency; contractility; endothelin

Indexed keywords

ADENOSINE TRIPHOSPHATASE; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CONTRACTILE PROTEIN; ENDOTHELIN; NITRIC OXIDE; NITRIC OXIDE SYNTHASE;

ENDOTHELIUM CELL; HEART MUSCLE CONTRACTILITY; HUMAN; HUMAN CELL; OXYGEN CONSUMPTION; OXYGEN TENSION; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RECEPTOR DOWN REGULATION; REVIEW; SHEAR STRESS;

ANIMALS; ENDOTHELINS; ENDOTHELIUM, VASCULAR; HUMANS; MYOCARDIAL CONTRACTION; OXYGEN; SIGNAL TRANSDUCTION; STRESS, MECHANICAL;

EID: 0030893599     PISSN: 00664278     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.physiol.59.1.505     Document Type: Review

References (55)

1. Alpert NR, Mulieri LA. 1983. Thermomechanical economy of hypertrophied hearts. In Perspectives in Cardiovascular Research, ed. NR Alpert, 7:619-30. New York: Raven
2. Awolesi M, Widmann M, Sessa W, Sumpio B. 1994. Cyclic strain increases endothelial nitric oxide synthase activity. Surgery 116:439
3. Balligrand J-L, Kelly RA, Marsden PA, Smith TW, Michel T. 1993. Control of cardiac muscle cell function by an endogenous nitric oxide signalling system. Proc. Natl. Acad. Sci. USA 90:347-51
4. Breisch EA, Houser SR, Coulson RL. 1983. Reduced heat production in compensated pressure-overload hypertrophy of the left ventricle of the cat. In Perspectives in Cardiovascular Research, ed. NR Alpert, 7:587-99. New York: Raven
5. Brutsaert DL, Meulemans AL, Sipido KJ, Sys SU. 1988. Effect of damaging the endocardial surface on the mechanical performance of isolated cardiac muscle. Circ. Res. 62:358-66
6. Carey R, Natarajan G, Bove A, Coulson R, Spann J. 1979. Myosin adenosine-tnphosphatase activity in the volume overloaded hypertrophied feline right ventricle. Circ. Res. 45:81-97
7. Ebihara Y, Haist JV, Karmazyn M. 1996. Modulation of endothelin-1 effects on rat hearts and cardiomyocytes by nitric oxide and 8-bromo cyclic GMP. J. Mol. Cell. Cardiol. 28:265-77
8. Endoh M, Takanashi M. 1991. Differential inhibitory action of phorbol-12,13-dibutyrate on the positive inotropic effect of endothelin-1 and Bay K8644 in the isolated rabbit papillary muscle. Cardiovasc. Res. 17(Suppl.7):25S165-68
9. Evans HG, Lewis MJ, Shah AM. 1994. Modulation of myocardial relaxation by basal release of endothelin from endocardial endothelium. Cardiovasc. Res. 28:1694-99
10. Fort S, Lewis MJ. 1993. A factor released from coronary vascular endothelium inhibits myocardial contractile performance. Am. J. Physiol. 264:H830-36
11. Frelin C, Guedin D. 1994. Why are circulating concentrations of endothelin-1 so low? Cardiovasc. Res. 28:1613-22
12. Furchgott R, Zawadski J. 1980. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle of acetylcholine. Nature 288:373-76
13. Grocott-Mason RM, Anning PB, Evans H, Lewis MJ, Shah AM. 1994. Modulation of left ventricular relaxation in isolated ejecting heart by endogenous nitric oxide. Am. J. Physiol. 267:H1804-13
14. Hasenfuss G, Mulieri L, Leavitt B, Alpert N. 1994. Influence of isoproterenol on contractile protein function, excitation-contraction coupling, and energy turnover of isolated nonfailing human heart. J. Mol. Cell. Cardiol. 26:1461-69
15. Hilal-Dandan R, Urasawa K, Brunton L. 1992. Endothelin inhibits adenylate cyclase and stimulates phosphoinositide hydrolysis in adult cardiac myocytes. J. Biol. Chem. 267:10620-24
16. Hoffman PA, Lange JH III. 1994. Effects of phosphorylation of troponin I and C protein on isometric tension and velocity of unloaded shortening in skinned single cardiac myocytes from rats. Circ. Res. 74:718-26
17. Hoh JFY, Rossmanith GH, Hamilton AM. 1991. Effects of dibutyryl cyclic AMP, ouabain, and xanthine derivatives on crossbridge kinetics in rat cardiac muscle. Circ. Res. 68:702
18. Jones L, Rozick J, Tsutsui H, Cooper G IV. 1992. Endothelin stimulates multiple responses in isolated ventricular cardiac myocytes. Am. J. Physiol. 263:H1447-54
19. Kagamu, Suzuki T, Arakawa, Mitsui Y. 1994. Low oxygen enhances endothelin-1 (ET-1) production and responsiveness to ET-1 in cultured cardiac myocytes. Biochem. Biophys. Res. Comm. 202:1612
20. Kasai H, Takanashi M, Takasaki C, Endoh M. 1994. Pharmacological properties of endothelin receptors subtypes mediating positive inotropic effects in rabbit heart. Am. J. Physiol. 266:H2220-28
21. Kato NS, Weisberg A, Winegrad S. 1991. Effect of left atrial filling pressure on the activity of specific myosin isozymes in rat heart. Circ. Res. SSI:1582-90
22. Kelly R, Eid H, Kramer B, O'Neill M, Liang B, et al. 1990. Endothelin enhances the contractile responsiveness of adult rat ventricular myocytes to calcium by a pertussis toxin sensitive pathway. Clin. Invest. 86:1164-71
23. Kojda G, Kottenberg K, Nix P, Schluter KD, Piper HM, Noack E. 1996. Low increase in cGMP induced by organic nitrates and nitrovasodilators improves contractile response of rat ventricular myocytes. Circ. Res. 78:91-101
24. Kramer B, Smith T, Kelly R. 1991. Endothelium and increased contractility in adult rat heart myocytes. Role of intracellular alkalosis induced by activation of protein kinase C-dependent Na-H exchanger. Circ. Res. 68:269-79
25. Kuchen MJ, Frangos JA. 1993. Shear stress regulates endothelium 1 release via a protein kinase C and cGMP in cultured endothelial cells. Am. J. Physiol. 264:H150-56
26. Lin L-E, McClellan GM, Weisberg A, Winegrad S. 1991. A physiological basis for the variation in the contractile properties of isolated rat heart. J. Physiol. 441:73-94
27. Margulies K, Hildebrand F Jr, Lerman A, Perella M, Burnett J Jr. 1990. Increased endothelin in experimental heart failure. Circulation 82:2226
28. McClellan GM, Weisberg A, Kato N, Ramaciotti C, Sharkey A, Winegrad S. 1992. Contractile proteins in myocardial cells are regulated by factor(s) released by blood vessels. Circ. Res. 70:787-803
29. McClellan GM, Weisberg A, Lin LE, Winegrad S. 1993. Endothelial cells are required for cAMP regulation of cardiac contractile proteins. Proc. Natl. Acad. Sci. USA 90:2885-89
30. McClellan GM, Weisberg A, Rose D, Winegrad S. 1994. Endothelial cell storage and release of endothelin as a cardioregulatory mechanism. Circ. Res. 75:85-96
31. McClellan GM, Weisberg A, Winegrad S. 1995. Endothelin regulation of cardiac contractility in the absence of added endothelin. Am. J. Physiol. 268:H1621-27
32. McClellan GM, Weisberg A, Winegrad S. 1995. Cyclic AMP can raise or lower actomyosin ATPase. Am. J. Physiol. 267:H431-42
33. McClellan GM, Weisberg A, Winegrad S. 1996. Effect of endothelin-1 on actomyosin ATPase activity: implications for the efficiency of contraction. Circ. Res. 78:1044-50
34. Mebazaa A, Mayoux E, Maeda K, Martin L, Lakatta EG, et al. 1993. Paracrine effects of endocardial endothelial cells on myocyte contraction via endothelin. Am. J. Physiol. 265:H1841-46
35. Mope L, McClellan GM, Winegrad S. 1980. Calcium sensitivity of the contractile system and phosphorylation of troponin in hyperpermeable cardiac cells. J. Gen. Physiol. 75:271-82
36. Ono K, Tsuujimoto G, Sakamoto A, Eto K, Masaki T, et al. 1994. Endothelin-A receptor mediates cardiac inhibition by regulating calcium and potassium currents. Nature 370:301-4
37. Paulus WJ, Vantrimpont PJ, Shah AM. 1995. Paracrine coronary endothelial control of left ventricular function in humans. Circulation 92:2119-26
38. Pohl U, Buss R. 1989. Differential vascular sensitivity to luminally and adventitially applied endothelin-1 J. Cardiovasc. Pharm. 13(Suppl. 5)S188-90
39. Ramaciotti C, McClellan G, Sharkey A, Rose D, Weisberg A, Winegrad S. 1993. Cardiac endothelial cells modulate contractility of rat heart in response to oxygen tension and coronary flow. Circ. Res. 72:1044-64
40. Ramaciotti C, Sharkey A, McClellan GM, Winegrad S. 1992. Endothelial cells regulate cardiac contractility. Proc. Natl. Acad. Sci. USA 89:4033-36
41. Robertson S, Johnson D, Holroyde M, Kranias I, Potter J, Solaro J. 1982. The effect of troponin 1 phosphorylation on the Ca binding properties of the calcium regulatory site of bovine cardiac troponin. J. Biol. Chem. 257:160
42. Shah AM, Mebazaa A, Wetzel RC, Lakatta EG. 1994. Novel cardiac myofilament desensitizing factor released by endocardial and vascular endothelial cells. Circulation 89:2492-97
43. Shah AM, Spurgeon HA, Sollott SJ, Talo A, Lakatta EG. 1994. 8-bromo-cGMP reduces the myofilament response to Ca in intact cardiac myocytes. Circ. Res. 74:970-78
44. Smith JA, Shah AM, Lewis MJ. 1991. Factors released from the endocardium of the ferret and pig modulate myocardial contraction. J. Physiol. 439:1-14
45. Stewart DJ, Langleben D, Ceracek P, Cianflone K. 1990. Endothelin release is inhibited by co-culture of endothelial cells with cells of vascular media. Am. J. Physiol. 259:H1928
46. Strang KT, Moss RL. 1995. Alpha adrenergic receptor stimulation decreases the maximum shortening velocity of skinned single ventricular myocytes from rats. Circ. Res. 77:114-20
47. Sweeney L, Stull J. 1990. Alterations of cross bridge kinetics by myosin light chain phosphorylation in rabbit skeletal muscle: implications for regulation of actin-myosin interactions. Proc. Natl. Acad. Sci. USA 87:414-18
48. Takanashi M, Endoh M. 1991. Characterization of positive inotropic effect of endothelin on mammalian ventricular myocardium. Am. J. Physiol. 261:H611-19
49. de Tombe PP, Stienen GJM. 1995. Protein kinase A does not alter economy of force maintenance in skinned cardiac rat trabeculae. Circ. Res. 76:734-41
50. Tonnessen T, Giaid A, Saleh D, Naess PA, Ynagisawa M, Christensen G. 1995. Increased in vivo expresssion and production of endothelin-1 by porcine cardiomyocytes subjected to ischemia. Circ. Res. 76:767-72
51. Venema RC, Kuo JF. 1993. Protein kinase C mediated phosphorylation of troponin I and C protein in isolated myocardial cells is associated with inhibition of myofibrillar actomyosin ATPase. J. Biol. Chem. 268:2705-11
52. 2+-responsiveness in aequorin loaded ferret myocardium. Circ. Res. 69:582-89
53. Weisberg A, Winegrad S. 1996. Alteration of myosin crossbridges by phosphorylation of myosin-binding protein C in cardiac muscle. Proc. Natl. Acad. Sci. USA 93:8999-9003
54. Wikman-Coffelt J, Fenner C, Coffelt R, Sabel A, Kamiyama T, Mason D. 1975. Chronological effects of mild pressure overload on myosin ATPase activity in the canine right ventricle. J. Mol. Cell. Cardiol. 7:219-24
55. Winegrad S, Weisberg A, Lin L-E, McClellan G. 1986. Adrenergic regulation of myosin adenosine triphosphatase activity. Circ. Res. 58:83-95