메뉴 건너뛰기




Volumn 11, Issue 3, 2012, Pages 604-616

Cyclin G-associated kinase regulates protein phosphatase 2A by phosphorylation of its B'γ subunit

Author keywords

Centrosome; CHK2; GAK; PP2A B' ; H2AX

Indexed keywords

BINDING PROTEIN; CYCLIN G; PHOSPHATASE; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN CYCLIN G ASSOCIATED KINASE; SMALL INTERFERING RNA; THREONINE; UNCLASSIFIED DRUG;

EID: 84857222543     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.11.3.19114     Document Type: Article
Times cited : (18)

References (53)
  • 1
    • 0037032835 scopus 로고    scopus 로고
    • The protein kinase complement of the human genome
    • PMID:12471243
    • Manning G, Whyte DB, Martinez R, Hunter T, Sudarsanam S. The protein kinase complement of the human genome. Science 2002; 298:1912-34; PMID:12471243; http://dx.doi.org/10.1126/science.1075762.
    • (2002) Science , vol.298 , pp. 1912-1934
    • Manning, G.1    Whyte, D.B.2    Martinez, R.3    Hunter, T.4    Sudarsanam, S.5
  • 2
    • 84882918966 scopus 로고    scopus 로고
    • Phosphatase families dephosphorylating serine and threonine residues in proteins
    • Bradshaw R, Dennis EA, Eds. London: Academic Press
    • Cohen PTW. Phosphatase families dephosphorylating serine and threonine residues in proteins. In: Bradshaw R, Dennis EA, Eds. Handbook of Cell Signaling. London: Academic Press 2009; 593-600.
    • (2009) Handbook of Cell Signaling , pp. 593-600
    • Cohen, P.T.W.1
  • 3
    • 41549090369 scopus 로고    scopus 로고
    • Multiple pathways regulated by the tumor suppressor PP2A in transformation
    • PMID:18329957
    • Westermarck J, Hahn WC. Multiple pathways regulated by the tumor suppressor PP2A in transformation. Trends Mol Med 2008; 14:152-60; PMID:18329957; http://dx.doi.org/10.1016/j.molmed.2008.02.001.
    • (2008) Trends Mol Med , vol.14 , pp. 152-160
    • Westermarck, J.1    Hahn, W.C.2
  • 4
    • 79960726254 scopus 로고    scopus 로고
    • Phosphatases: Providing safe passage through mitotic exit
    • PMID:21750572
    • Wurzenberger C, Gerlich DW. Phosphatases: providing safe passage through mitotic exit. Nat Rev Mol Cell Biol 2011; 12:469-82; PMID:21750572; http://dx.doi.org/10.1038/nrm3149.
    • (2011) Nat Rev Mol Cell Biol , vol.12 , pp. 469-482
    • Wurzenberger, C.1    Gerlich, D.W.2
  • 5
    • 12344308021 scopus 로고    scopus 로고
    • PP2A: The expected tumor suppressor
    • PMID:15661531
    • Janssens V, Goris J, Van Hoof C. PP2A: the expected tumor suppressor. Curr Opin Genet Dev 2005; 15:34-41; PMID:15661531; http://dx.doi.org/10.1016/j. gde.2004.12.004.
    • (2005) Curr Opin Genet Dev , vol.15 , pp. 34-41
    • Janssens, V.1    Goris, J.2    Van Hoof, C.3
  • 6
    • 61649127812 scopus 로고    scopus 로고
    • From promiscuity to precision: Protein phosphatases get a makeover
    • PMID:19285938
    • Virshup DM, Shenolikar S. From promiscuity to precision: protein phosphatases get a makeover. Mol Cell 2009; 33:537-45; PMID:19285938; http://dx.doi.org/10.1016/j.molcel.2009.02.015.
    • (2009) Mol Cell , vol.33 , pp. 537-545
    • Virshup, D.M.1    Shenolikar, S.2
  • 7
    • 70350340056 scopus 로고    scopus 로고
    • Serine/threonine phosphatases: Mechanism through structure
    • PMID:19879837
    • Shi Y. Serine/threonine phosphatases: mechanism through structure. Cell 2009; 139:468-84; PMID:19879837; http://dx.doi.org/10.1016/j.cell.2009.10.006.
    • (2009) Cell , vol.139 , pp. 468-484
    • Shi, Y.1
  • 8
    • 0034651747 scopus 로고    scopus 로고
    • A truncated isoform of the PP2A B56 subunit promotes cell motility through paxillin phosphorylation
    • PMID:10675325
    • Ito A, Kataoka TR, Watanabe M, Nishiyama K, Mazaki Y, Sabe H, et al. A truncated isoform of the PP2A B56 subunit promotes cell motility through paxillin phosphorylation. EMBO J 2000; 19:562-71; PMID:10675325; http://dx.doi.org/10.1093/emboj/19.4.562.
    • (2000) EMBO J , vol.19 , pp. 562-571
    • Ito, A.1    Kataoka, T.R.2    Watanabe, M.3    Nishiyama, K.4    Mazaki, Y.5    Sabe, H.6
  • 9
    • 0036235121 scopus 로고    scopus 로고
    • Cyclin G recruits PP2A to dephosphorylate Mdm2
    • PMID:11983168
    • Okamoto K, Li H, Jensen MR, Zhang T, Taya Y, Thorgeirsson SS, et al. Cyclin G recruits PP2A to dephosphorylate Mdm2. Mol Cell 2002; 9:761-71; PMID:11983168; http://dx.doi.org/10.1016/S1097-2765(02)00504-X.
    • (2002) Mol Cell , vol.9 , pp. 761-771
    • Okamoto, K.1    Li, H.2    Jensen, M.R.3    Zhang, T.4    Taya, Y.5    Thorgeirsson, S.S.6
  • 10
    • 0036668475 scopus 로고    scopus 로고
    • Cyclin G1 associates with MDM2 and regulates accumulation and degradation of p53 protein
    • PMID:12167164
    • Kimura SH, Nojima H. Cyclin G1 associates with MDM2 and regulates accumulation and degradation of p53 protein. Genes Cells 2002; 7:869-80; PMID:12167164; http://dx.doi.org/10.1046/j.1365-2443.2002.00564.x.
    • (2002) Genes Cells , vol.7 , pp. 869-880
    • Kimura, S.H.1    Nojima, H.2
  • 11
    • 0034978891 scopus 로고    scopus 로고
    • Cyclin G1 is involved in G2/M arrest in response to DNA damage and in growth control after damage recovery
    • PMID:11423978
    • Kimura SH, Ikawa M, Ito A, Okabe M, Nojima H. Cyclin G1 is involved in G2/M arrest in response to DNA damage and in growth control after damage recovery. Oncogene 2001; 20:3290-300; PMID:11423978; http://dx.doi.org/10.1038/ sj.onc.1204270.
    • (2001) Oncogene , vol.20 , pp. 3290-3300
    • Kimura, S.H.1    Ikawa, M.2    Ito, A.3    Okabe, M.4    Nojima, H.5
  • 12
    • 0036101808 scopus 로고    scopus 로고
    • Cyclin G: A regulator of the p53-Mdm2 network
    • PMID:12015958
    • Chen X. Cyclin G: a regulator of the p53-Mdm2 network. Dev Cell 2002; 2:518-9; PMID:12015958; http://dx.doi.org/10.1016/S1534-5807(02)00182-X.
    • (2002) Dev Cell , vol.2 , pp. 518-519
    • Chen, X.1
  • 13
    • 0037178863 scopus 로고    scopus 로고
    • Cyclin G2 associates with protein phosphatase 2A catalytic and regulatory B'subunits in active complexes and induces nuclear aberrations and a G1/S phase cell cycle arrest
    • PMID:11956189
    • Bennin DA, Don ASA, Brake T, McKenzie JL, Rosenbaum H, Ortiz L, et al. Cyclin G2 associates with protein phosphatase 2A catalytic and regulatory B'subunits in active complexes and induces nuclear aberrations and a G1/S phase cell cycle arrest. J Biol Chem 2002; 277:27449-67; PMID:11956189; http://dx.doi.org/10.1074/jbc.M111693200.
    • (2002) J Biol Chem , vol.277 , pp. 27449-27467
    • Bennin, D.A.1    Don, A.S.A.2    Brake, T.3    McKenzie, J.L.4    Rosenbaum, H.5    Ortiz, L.6
  • 14
    • 79952326099 scopus 로고    scopus 로고
    • Drosophila melanogaster cyclin G coordinates cell growth and cell proliferation
    • PMID:21311225
    • Faradji F, Bloyer S, Dardalhon-Cuménal D, Randsholt NB, Peronnet F. Drosophila melanogaster cyclin G coordinates cell growth and cell proliferation. Cell Cycle 2011; 10:805-18; PMID:21311225; http://dx.doi.org/10. 4161/cc.10.5.14959.
    • (2011) Cell Cycle , vol.10 , pp. 805-818
    • Faradji, F.1    Bloyer, S.2    Dardalhon-Cuménal, D.3    Randsholt, N.B.4    Peronnet, F.5
  • 15
    • 79954473027 scopus 로고    scopus 로고
    • More about cyclin G from flies
    • PMID:21441780
    • Montagne J. More about cyclin G from flies. Cell Cycle 2011; 10:1187-8; PMID:21441780; http://dx.doi.org/10.4161/cc.10.8.15296.
    • (2011) Cell Cycle , vol.10 , pp. 1187-1188
    • Montagne, J.1
  • 16
    • 0031023433 scopus 로고    scopus 로고
    • GAK: A cyclin G associated kinase contains a tensin/auxilin-like domain
    • PMID:9013862
    • Kanaoka Y, Kimura SH, Okazaki I, Ikeda M, Nojima H. GAK: a cyclin G associated kinase contains a tensin/auxilin-like domain. FEBS Lett 1997; 402:73-80; PMID:9013862; http://dx.doi.org/10.1016/S0014-5793(96)01484-6.
    • (1997) FEBS Lett , vol.402 , pp. 73-80
    • Kanaoka, Y.1    Kimura, S.H.2    Okazaki, I.3    Ikeda, M.4    Nojima, H.5
  • 17
    • 34249058118 scopus 로고    scopus 로고
    • Multiple roles of auxilin and hsc70 in clathrin-mediated endocytosis
    • PMID:17488288
    • Eisenberg E, Greene LE. Multiple roles of auxilin and hsc70 in clathrin-mediated endocytosis. Traffic 2007; 8:640-6; PMID:17488288; http://dx.doi.org/10.1111/j.1600-0854.2007.00568.x.
    • (2007) Traffic , vol.8 , pp. 640-646
    • Eisenberg, E.1    Greene, L.E.2
  • 18
    • 69249137477 scopus 로고    scopus 로고
    • Endocytosis and signalling: Intertwining molecular networks
    • PMID:19696798
    • Sorkin A, von Zastrow M. Endocytosis and signalling: intertwining molecular networks. Nat Rev Mol Cell Biol 2009; 10:609-22; PMID:19696798; http://dx.doi.org/10.1038/nrm2748.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 609-622
    • Sorkin, A.1    Von Zastrow, M.2
  • 19
    • 31844450987 scopus 로고    scopus 로고
    • Cyclin G-associated kinase: A novel androgen receptor-interacting transcriptional coactivator that is overexpressed in hormone refractory prostate cancer
    • PMID:16161052
    • Ray MR, Wafa LA, Cheng H, Snoek R, Fazli L, Gleave M, et al. Cyclin G-associated kinase: a novel androgen receptor-interacting transcriptional coactivator that is overexpressed in hormone refractory prostate cancer. Int J Cancer 2006; 118:1108-19; PMID:16161052; http://dx.doi.org/10.1002/ijc.21469.
    • (2006) Int J Cancer , vol.118 , pp. 1108-1119
    • Ray, M.R.1    Wafa, L.A.2    Cheng, H.3    Snoek, R.4    Fazli, L.5    Gleave, M.6
  • 20
    • 65449137085 scopus 로고    scopus 로고
    • GAK, a regulator of clathrin-mediated membrane trafficking, localizes not only in the cytoplasm but also in the nucleus
    • PMID:19371378
    • Sato J, Shimizu H, Kasama T, Yabuta N, Nojima H. GAK, a regulator of clathrin-mediated membrane trafficking, localizes not only in the cytoplasm but also in the nucleus. Genes Cells 2009; 14:627-41; PMID:19371378; http://dx.doi.org/10.1111/j.1365-2443.2009.01296.x.
    • (2009) Genes Cells , vol.14 , pp. 627-641
    • Sato, J.1    Shimizu, H.2    Kasama, T.3    Yabuta, N.4    Nojima, H.5
  • 21
    • 70350418722 scopus 로고    scopus 로고
    • GAK, a regulator of clathrin-mediated membrane traffic, also controls centrosome integrity and chromosome congression
    • PMID:19654208
    • Shimizu H, Nagamori I, Yabuta N, Nojima H. GAK, a regulator of clathrin-mediated membrane traffic, also controls centrosome integrity and chromosome congression. J Cell Sci 2009; 122:3145-52; PMID:19654208; http://dx.doi.org/10.1242/jcs.052795.
    • (2009) J Cell Sci , vol.122 , pp. 3145-3152
    • Shimizu, H.1    Nagamori, I.2    Yabuta, N.3    Nojima, H.4
  • 22
    • 0036300863 scopus 로고    scopus 로고
    • CK2 and GAK/auxilin2 are major protein kinases in clathrin-coated vesicles
    • PMID:12010461
    • Korolchuk VI, Banting G. CK2 and GAK/auxilin2 are major protein kinases in clathrin-coated vesicles. Traffic 2002; 3:428-39; PMID:12010461; http://dx.doi.org/10.1034/j.1600-0854.2002.30606.x.
    • (2002) Traffic , vol.3 , pp. 428-439
    • Korolchuk, V.I.1    Banting, G.2
  • 23
    • 28444483130 scopus 로고    scopus 로고
    • Gamma-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair
    • PMID:16310392
    • Chowdhury D, Keogh MC, Ishii H, Peterson CL, Buratowski S, Lieberman J. gamma-H2AX dephosphorylation by protein phosphatase 2A facilitates DNA double-strand break repair. Mol Cell 2005; 20:801-9; PMID:16310392; http://dx.doi.org/10.1016/j.molcel.2005.10.003.
    • (2005) Mol Cell , vol.20 , pp. 801-809
    • Chowdhury, D.1    Keogh, M.C.2    Ishii, H.3    Peterson, C.L.4    Buratowski, S.5    Lieberman, J.6
  • 24
    • 0037424258 scopus 로고    scopus 로고
    • Polo-like kinase 1 and Chk2 interact and co-localize to centrosomes and the midbody
    • PMID:12493754
    • Tsvetkov L, Xu X, Li J, Stern DF. Polo-like kinase 1 and Chk2 interact and co-localize to centrosomes and the midbody. J Biol Chem 2003; 278:8468-75; PMID:12493754; http://dx.doi.org/10.1074/jbc.M211202200.
    • (2003) J Biol Chem , vol.278 , pp. 8468-8475
    • Tsvetkov, L.1    Xu, X.2    Li, J.3    Stern, D.F.4
  • 25
    • 79955634092 scopus 로고    scopus 로고
    • Protein phosphatase 1 regulators in DNA damage signaling
    • PMID:21451260
    • Küntziger TT, Landsverk HB, Collas P, Syljuåsen RG. Protein phosphatase 1 regulators in DNA damage signaling. Cell Cycle 2011; 10:1356-62; PMID:21451260; http://dx.doi.org/10.4161/cc.10.9.15442.
    • (2011) Cell Cycle , vol.10 , pp. 1356-1362
    • Küntziger, T.T.1    Landsverk, H.B.2    Collas, P.3    Syljuåsen, R.G.4
  • 26
    • 24944485819 scopus 로고    scopus 로고
    • Cancer-associated PP2A Aalpha subunits induce functional haploinsufficiency and tumorigenicity
    • PMID:16166293
    • Chen W, Arroyo JD, Timmons JC, Possemato R, Hahn WC. Cancer-associated PP2A Aalpha subunits induce functional haploinsufficiency and tumorigenicity. Cancer Res 2005; 65:8183-92; PMID:16166293; http://dx.doi.org/10.1158/0008-5472. CAN-05-1103.
    • (2005) Cancer Res , vol.65 , pp. 8183-8192
    • Chen, W.1    Arroyo, J.D.2    Timmons, J.C.3    Possemato, R.4    Hahn, W.C.5
  • 27
    • 34249291096 scopus 로고    scopus 로고
    • The tumor suppressor PP2A Abeta regulates the RalA GTPase
    • PMID:17540176
    • Sablina AA, Chen W, Arroyo JD, Corral L, Hector M, Bulmer SE, et al. The tumor suppressor PP2A Abeta regulates the RalA GTPase. Cell 2007; 129:969-82; PMID:17540176; http://dx.doi.org/10.1016/j.cell.2007.03.047.
    • (2007) Cell , vol.129 , pp. 969-982
    • Sablina, A.A.1    Chen, W.2    Arroyo, J.D.3    Corral, L.4    Hector, M.5    Bulmer, S.E.6
  • 28
    • 9144223779 scopus 로고    scopus 로고
    • Critical role for protein phosphatase 2A heterotrimers in mammalian cell survival
    • PMID:15364932
    • Strack S, Cribbs JT, Gomez L. Critical role for protein phosphatase 2A heterotrimers in mammalian cell survival. J Biol Chem 2004; 279:47732-9; PMID:15364932; http://dx.doi.org/10.1074/jbc.M408015200.
    • (2004) J Biol Chem , vol.279 , pp. 47732-47739
    • Strack, S.1    Cribbs, J.T.2    Gomez, L.3
  • 29
    • 77953300022 scopus 로고    scopus 로고
    • Nuclear export and centrosome targeting of the protein phosphatase 2A subunit B56alpha: Role of B56alpha in nuclear export of the catalytic subunit
    • PMID:20378546
    • Flegg CP, Sharma M, Medina-Palazon C, Jamieson C, Galea M, Brocardo MG, et al. Nuclear export and centrosome targeting of the protein phosphatase 2A subunit B56alpha: role of B56alpha in nuclear export of the catalytic subunit. J Biol Chem 2010; 285:18144-54; PMID:20378546; http://dx.doi.org/10.1074/jbc. M109.093294.
    • (2010) J Biol Chem , vol.285 , pp. 18144-18154
    • Flegg, C.P.1    Sharma, M.2    Medina-Palazon, C.3    Jamieson, C.4    Galea, M.5    Brocardo, M.G.6
  • 30
    • 33845404441 scopus 로고    scopus 로고
    • Structure of the protein phosphatase 2A holoenzyme
    • PMID:17174897
    • Xu Y, Xing Y, Chen Y, Chao Y, Lin Z, Fan E, et al. Structure of the protein phosphatase 2A holoenzyme. Cell 2006; 127:1239-51; PMID:17174897; http://dx.doi.org/10.1016/j.cell.2006.11.033.
    • (2006) Cell , vol.127 , pp. 1239-1251
    • Xu, Y.1    Xing, Y.2    Chen, Y.3    Chao, Y.4    Lin, Z.5    Fan, E.6
  • 31
    • 33846118688 scopus 로고    scopus 로고
    • Crystal structure of a protein phosphatase 2A heterotrimeric holoenzyme
    • PMID:17086192
    • Cho US, Xu W. Crystal structure of a protein phosphatase 2A heterotrimeric holoenzyme. Nature 2007; 445:53-7; PMID:17086192; http://dx.doi.org/10.1038/nature05351.
    • (2007) Nature , vol.445 , pp. 53-57
    • Cho, U.S.1    Xu, W.2
  • 32
    • 33644524383 scopus 로고    scopus 로고
    • B56-containing PP2A dephosphorylate ERK and their activity is controlled by the early gene IEX-1 and ERK
    • PMID:16456541
    • Letourneux C, Rocher G, Porteu F. B56-containing PP2A dephosphorylate ERK and their activity is controlled by the early gene IEX-1 and ERK. EMBO J 2006; 25:727-38; PMID:16456541; http://dx.doi.org/10.1038/sj.emboj.7600980.
    • (2006) EMBO J , vol.25 , pp. 727-738
    • Letourneux, C.1    Rocher, G.2    Porteu, F.3
  • 33
    • 33646893725 scopus 로고    scopus 로고
    • Protein phosphatase 2A stabilizes human securin, whose phosphorylated forms are degraded via the SCF ubiquitin ligase
    • PMID:16705156
    • Gil-Bernabé AM, Romero F, Limón-Mortés MC, Tortolero M. Protein phosphatase 2A stabilizes human securin, whose phosphorylated forms are degraded via the SCF ubiquitin ligase. Mol Cell Biol 2006; 26:4017-27; PMID:16705156; http://dx.doi.org/10.1128/MCB.01904-05.
    • (2006) Mol Cell Biol , vol.26 , pp. 4017-4027
    • Gil-Bernabé, A.M.1    Romero, F.2    Limón-Mortés, M.C.3    Tortolero, M.4
  • 34
    • 79955583900 scopus 로고    scopus 로고
    • PP2A (Cdc)55 is required for multiple events during meiosis I
    • PMID:21455032
    • Nolt JK, Rice LM, Gallo-Ebert C, Bisher ME, Nickels JT. PP2A (Cdc)55 is required for multiple events during meiosis I. Cell Cycle 2011; 10:1420-34; PMID:21455032; http://dx.doi.org/10.4161/cc.10.9.15485.
    • (2011) Cell Cycle , vol.10 , pp. 1420-1434
    • Nolt, J.K.1    Rice, L.M.2    Gallo-Ebert, C.3    Bisher, M.E.4    Nickels, J.T.5
  • 35
    • 33751212191 scopus 로고    scopus 로고
    • Role for the PP2A/B56delta phosphatase in regulating 14-3-3 release from Cdc25 to control mitosis
    • PMID:17110335
    • Margolis SS, Perry JA, Forester CM, Nutt LK, Guo Y, Jardim MJ, et al. Role for the PP2A/B56delta phosphatase in regulating 14-3-3 release from Cdc25 to control mitosis. Cell 2006; 127:759-73; PMID:17110335; http://dx.doi.org/10. 1016/j.cell.2006.10.035.
    • (2006) Cell , vol.127 , pp. 759-773
    • Margolis, S.S.1    Perry, J.A.2    Forester, C.M.3    Nutt, L.K.4    Guo, Y.5    Jardim, M.J.6
  • 36
    • 33646795889 scopus 로고    scopus 로고
    • Shugoshin collaborates with protein phosphatase 2A to protect cohesin
    • PMID:16541025
    • Kitajima TS, Sakuno T, Ishiguro Ki, Iemura Si, Natsume T, Kawashima SA, et al. Shugoshin collaborates with protein phosphatase 2A to protect cohesin. Nature 2006; 441:46-52; PMID:16541025; http://dx.doi.org/10.1038/nature04663.
    • (2006) Nature , vol.441 , pp. 46-52
    • Kitajima, T.S.1    Sakuno, T.2    Ishiguro, Ki.3    Iemura, Si.4    Natsume, T.5    Kawashima, S.A.6
  • 37
    • 37749045815 scopus 로고    scopus 로고
    • Unified mode of centromeric protection by shugoshin in mammalian oocytes and somatic cells
    • PMID:18084284
    • Lee J, Kitajima TS, Tanno Y, Yoshida K, Morita T, Miyano T, et al. Unified mode of centromeric protection by shugoshin in mammalian oocytes and somatic cells. Nat Cell Biol 2008; 10:42-52; PMID:18084284; http://dx.doi.org/ 10.1038/ncb1667.
    • (2008) Nat Cell Biol , vol.10 , pp. 42-52
    • Lee, J.1    Kitajima, T.S.2    Tanno, Y.3    Yoshida, K.4    Morita, T.5    Miyano, T.6
  • 38
    • 77956840220 scopus 로고    scopus 로고
    • Fighting of Casein kinase 1 and PP2A/Shugoshin for cohesins during meiosis I
    • PMID:20740713
    • Suja JA. Fighting of Casein kinase 1 and PP2A/Shugoshin for cohesins during meiosis I. Cell Cycle 2010; 9:2929-30; PMID:20740713; http://dx.doi.org/10.4161/cc.9.15.12696.
    • (2010) Cell Cycle , vol.9 , pp. 2929-2930
    • Suja, J.A.1
  • 39
    • 71449108833 scopus 로고    scopus 로고
    • The chromosomal association of condensin II is regulated by a noncatalytic function of PP2A
    • PMID:19915589
    • Takemoto A, Maeshima K, Ikehara T, Yamaguchi K, Murayama A, Imamura S, et al. The chromosomal association of condensin II is regulated by a noncatalytic function of PP2A. Nat Struct Mol Biol 2009; 16:1302-8; PMID:19915589; http://dx.doi.org/10.1038/nsmb.1708.
    • (2009) Nat Struct Mol Biol , vol.16 , pp. 1302-1308
    • Takemoto, A.1    Maeshima, K.2    Ikehara, T.3    Yamaguchi, K.4    Murayama, A.5    Imamura, S.6
  • 40
    • 21744452482 scopus 로고    scopus 로고
    • Chromokinesins: Multitalented players in mitosis
    • PMID:15946846
    • Mazumdar M, Misteli T. Chromokinesins: multitalented players in mitosis. Trends Cell Biol 2005; 15:349-55; PMID:15946846; http://dx.doi.org/10.1016/j. tcb.2005.05.006.
    • (2005) Trends Cell Biol , vol.15 , pp. 349-355
    • Mazumdar, M.1    Misteli, T.2
  • 41
    • 33746770369 scopus 로고    scopus 로고
    • Structure meets function - Centrosomes, genome maintenance and the DNA damage response
    • PMID:16854412
    • Löffler H, Lukas J, Bartek J, Krämer A. Structure meets function - centrosomes, genome maintenance and the DNA damage response. Exp Cell Res 2006; 312:2633-40; PMID:16854412; http://dx.doi.org/10.1016/j.yexcr.2006. 06.008.
    • (2006) Exp Cell Res , vol.312 , pp. 2633-2640
    • Löffler, H.1    Lukas, J.2    Bartek, J.3    Krämer, A.4
  • 42
    • 34247875990 scopus 로고    scopus 로고
    • Centrosomal localization of DNA damage checkpoint proteins
    • PMID:17171639
    • Zhang S, Hemmerich P, Grosse F. Centrosomal localization of DNA damage checkpoint proteins. J Cell Biochem 2007; 101:451-65; PMID:17171639; http://dx.doi.org/10.1002/jcb.21195.
    • (2007) J Cell Biochem , vol.101 , pp. 451-465
    • Zhang, S.1    Hemmerich, P.2    Grosse, F.3
  • 43
    • 70149105262 scopus 로고    scopus 로고
    • Emerging connection between centrosome and DNA repair machinery
    • Tokyo PMID:19542690
    • Shimada M, Komatsu K. Emerging connection between centrosome and DNA repair machinery. J Radiat Res (Tokyo) 2009; 50:295-301; PMID:19542690; http://dx.doi.org/10.1269/jrr.09039.
    • (2009) J Radiat Res , vol.50 , pp. 295-301
    • Shimada, M.1    Komatsu, K.2
  • 44
    • 57349164068 scopus 로고    scopus 로고
    • Cdc25A serine 123 phosphorylation couples centrosome duplication with DNA replication and regulates tumorigenesis
    • PMID:18936171
    • Shreeram S, Hee WK, Bulavin DV. Cdc25A serine 123 phosphorylation couples centrosome duplication with DNA replication and regulates tumorigenesis. Mol Cell Biol 2008; 28:7442-50; PMID:18936171; http://dx.doi.org/10.1128/MCB.00138- 08.
    • (2008) Mol Cell Biol , vol.28 , pp. 7442-7450
    • Shreeram, S.1    Hee, W.K.2    Bulavin, D.V.3
  • 45
    • 34547103279 scopus 로고    scopus 로고
    • Lats2 is an essential mitotic regulator required for the coordination of cell division
    • PMID:17478426
    • Yabuta N, Okada N, Ito A, Hosomi T, Nishihara S, Sasayama Y, et al. Lats2 is an essential mitotic regulator required for the coordination of cell division. J Biol Chem 2007; 282:19259-71; PMID:17478426; http://dx.doi.org/10. 1074/jbc.M608562200.
    • (2007) J Biol Chem , vol.282 , pp. 19259-19271
    • Yabuta, N.1    Okada, N.2    Ito, A.3    Hosomi, T.4    Nishihara, S.5    Sasayama, Y.6
  • 46
    • 70549105789 scopus 로고    scopus 로고
    • Making the Auroras glow: Regulation of Aurora A and B kinase function by interacting proteins
    • PMID:19836940
    • Carmena M, Ruchaud S, Earnshaw WC. Making the Auroras glow: regulation of Aurora A and B kinase function by interacting proteins. Curr Opin Cell Biol 2009; 21:796-805; PMID:19836940; http://dx.doi.org/10.1016/j.ceb.2009.09.008.
    • (2009) Curr Opin Cell Biol , vol.21 , pp. 796-805
    • Carmena, M.1    Ruchaud, S.2    Earnshaw, W.C.3
  • 47
    • 77954159791 scopus 로고    scopus 로고
    • Mitotic DNA damage response: Polo-like kinase-1 is dephosphorylated through ATM-Chk1 pathway
    • PMID:20581453
    • Lee HJ, Hwang HI, Jang YJ. Mitotic DNA damage response: Polo-like kinase-1 is dephosphorylated through ATM-Chk1 pathway. Cell Cycle 2010; 9:2389-98; PMID:20581453; http://dx.doi.org/10.4161/cc.9.12.11904.
    • (2010) Cell Cycle , vol.9 , pp. 2389-2398
    • Lee, H.J.1    Hwang, H.I.2    Jang, Y.J.3
  • 48
    • 74949108644 scopus 로고    scopus 로고
    • The complexity of phosphorylated H2AX foci formation and DNA repair assembly at DNA double-strand breaks
    • PMID:20046100
    • Nakamura AJ, Rao VA, Pommier Y, Bonner WM. The complexity of phosphorylated H2AX foci formation and DNA repair assembly at DNA double-strand breaks. Cell Cycle 2010; 9:389-97; PMID:20046100; http://dx.doi.org/10.4161/cc. 9.2.10475.
    • (2010) Cell Cycle , vol.9 , pp. 389-397
    • Nakamura, A.J.1    Rao, V.A.2    Pommier, Y.3    Bonner, W.M.4
  • 49
    • 70350771277 scopus 로고    scopus 로고
    • Centrioles, centrosomes and cilia in health and disease
    • PMID:19914163
    • Nigg EA, Raff JW. Centrioles, centrosomes and cilia in health and disease. Cell 2009; 139:663-78; PMID:19914163; http://dx.doi.org/10.1016/j.cell. 2009.10.036.
    • (2009) Cell , vol.139 , pp. 663-678
    • Nigg, E.A.1    Raff, J.W.2
  • 50
    • 77953150977 scopus 로고    scopus 로고
    • Negative regulation of CHK2 activity by protein phosphatase 2A is modulated by DNA damage
    • PMID:20160490
    • Freeman AK, Dapic V, Monteiro ANA. Negative regulation of CHK2 activity by protein phosphatase 2A is modulated by DNA damage. Cell Cycle 2010; 9:736-47; PMID:20160490; http://dx.doi.org/10.4161/cc.9.4.10613.
    • (2010) Cell Cycle , vol.9 , pp. 736-747
    • Freeman, A.K.1    Dapic, V.2    Monteiro, A.N.A.3
  • 51
    • 77953500299 scopus 로고    scopus 로고
    • Fine-tuning the DNA damage response: Protein phosphatase 2A checks on CHK2
    • PMID:20348841
    • Smolka M. Fine-tuning the DNA damage response: protein phosphatase 2A checks on CHK2. Cell Cycle 2010; 9:862-3; PMID:20348841; http://dx.doi.org/10. 4161/cc.9.5.10906.
    • (2010) Cell Cycle , vol.9 , pp. 862-863
    • Smolka, M.1
  • 52
    • 34447106751 scopus 로고    scopus 로고
    • PP2A: Unveiling a reluctant tumor suppressor
    • PMID:17632053
    • Mumby M. PP2A: unveiling a reluctant tumor suppressor. Cell 2007; 130:21-4; PMID:17632053; http://dx.doi.org/10.1016/j.cell.2007.06.034.
    • (2007) Cell , vol.130 , pp. 21-24
    • Mumby, M.1
  • 53
    • 0037221975 scopus 로고    scopus 로고
    • A truncated isoform of the protein phosphatase 2A B56gamma regulatory subunit may promote genetic instability and cause tumor progression
    • PMID:12507892
    • Ito A, Koma YI, Watabe K, Nagano T, Endo Y, Nojima H, et al. A truncated isoform of the protein phosphatase 2A B56gamma regulatory subunit may promote genetic instability and cause tumor progression. Am J Pathol 2003; 162:81-91; PMID:12507892; http://dx.doi.org/10.1016/S0002-9440(10)63800-X.
    • (2003) Am J Pathol , vol.162 , pp. 81-91
    • Ito, A.1    Koma, Y.I.2    Watabe, K.3    Nagano, T.4    Endo, Y.5    Nojima, H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.