Sprouty2 and -4 regulate axon outgrowth by hippocampal neurons

Hippocampus

Volumn 22, Issue 3, 2012, Pages 434-441

  Hausott, Barbara ^a   Vallant, Natalie ^a   Schlick, Bettina ^a   Auer, Maria ^a   Nimmervoll, Benedikt ^a   Obermair, Gerald J ^a   Schwarzer, Christoph ^a   Dai, Fangping ^b   Brand Saberi, Beate ^b,c   Klimaschewski, Lars ^a  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^b UNIVERSITY OF FREIBURG   (Germany)

^c RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

Axon growth; Development; Fibroblast growth factor 2; Hippocampus; Sprouty

Indexed keywords

SHORT HAIRPIN RNA; SPROUTY 2 PROTEIN; SPROUTY 4 PROTEIN; SPROUTY PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BRAIN TISSUE; CELL CULTURE; CONTROLLED STUDY; CYTOPLASM; DENDRITE; DOWN REGULATION; EMBRYO; GENETIC TRANSFECTION; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MOUSE; NERVE CELL DIFFERENTIATION; NERVE ELONGATION; NERVE GROWTH; NONHUMAN; PERINATAL PERIOD; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; RNA TRANSLATION; WESTERN BLOTTING;

ANIMALS; AXONS; CELLS, CULTURED; DOWN-REGULATION; FIBROBLAST GROWTH FACTORS; GROWTH CONES; HIPPOCAMPUS; MEMBRANE PROTEINS; MICE; NERVE TISSUE PROTEINS; NEURONS; TRANSFECTION;

EID: 84857219372     PISSN: 10509631     EISSN: 10981063     Source Type: Journal    
DOI: 10.1002/hipo.20910     Document Type: Article

References (33)

1. Aranda S, Alvarez M, Turro S, Laguna A, de la Luna S. 2008. Sprouty2-mediated inhibition of fibroblast growth factor signaling is modulated by the protein kinase DYRK1A. Mol Cell Biol 28: 5899-5911.
2. Chambers D, Mason I. 2000. Expression of sprouty2 during early development of the chick embryo is coincident with known sites of FGF signalling. Mech Dev 91: 361-364.
3. Chambers D, Medhurst AD, Walsh FS, Price J, Mason I. 2000. Differential display of genes expressed at the midbrain-hindbrain junction identifies sprouty2: An FGF8-inducible member of a family of intracellular FGF antagonists. Mol Cell Neurosci 15: 22-35.
4. Dikic I, Giordano S. 2003. Negative receptor signalling. Curr Opin Cell Biol 15: 128-135.
5. Endoh M, Pulsinelli WA, Wagner JA. 1994. Transient global-ischemia induces dynamic changes in the expression of Bfgf and the Fgf receptor. Mol Brain Res 22: 76-88.
6. Fong CW, Leong HF, Wong ESM, Lim J, Yusoff P, Guy GR. 2003. Tyrosine phosphorylation of Sprouty2 enhances its interaction with c-Cbl and is crucial for its function. J Biol Chem 278: 33456-33464.
7. Gomez-Pinilla F, Lee JWK, Cotman CW. 1994. Distribution of basic fibroblast growth-factor in the developing rat-brain. Neuroscience 61: 911-923.
8. Goslin K, Asmussen H, Banker G. 1998. Rat hippocampal neurons in low-density culture. In: Banker G, Goslin K, editors. Culturing Nerve Cells. Cambridge, MA: MIT. pp 339-370.
9. Gross I, Bassit B, Benezra M, Licht JD. 2001. Mammalian Sprouty proteins inhibit cell growth and differentiation by preventing Ras activation. J Biol Chem 276: 46460-46468.
10. Gross I, Armant O, Benosman S, de Aguilar JLG, Freund JN, Kedinger M, Licht JD, Gaiddon C, Loeffler JP. 2007. Sprouty2 inhibits BDNF-induced signaling and modulates neuronal differentiation and survival. Cell Death Differ 14: 1802-1812.
11. Hanafusa H, Torii S, Yasunaga T, Nishida E. 2002. Sprouty1 and Sprouty2 provide a control mechanism for the Ras/MAPK signalling pathway. Nat Cell Biol 4: 850-858.
12. Hausott B, Vallant N, Auer M, Yang L, Dai F, Brand-Saberi B, Klimaschewski L. 2009. Sprouty2 down-regulation promotes axon growth by adult sensory neurons. Mol Cell Neurosci 42: 328-340.
13. Lin TN, Te J, Lee M, Sun GY, Hsu CY. 1997. Induction of basic fibroblast growth factor (bFGF) expression following focal cerebral ischemia. Mol Brain Res 49: 255-265.
14. Mason JM, Morrison DJ, Bassit B, Dimri M, Band H, Licht JD, Gross I. 2004. Tyrosine phosphorylation of sprouty proteins regulates their ability to inhibit growth factor signaling: A dual feedback loop. Mol Biol Cell 15: 2176-2188.
15. Mason JM, Morrison DJ, Basson MA, Licht JD. 2006. Sprouty proteins: Multifaceted negative-feed back regulators of receptor tyrosine kinase signaling. Trends Cell Biol 16: 45-54.
16. Minowada G, Jarvis LA, Chi CL, Neubuser A, Sun X, Hacohen N, Krasnow MA, Martin GR. 1999. Vertebrate Sprouty genes are induced by FGF signaling and can cause chondrodysplasia when overexpressed. Development 126: 4465-4475.
17. 2+-activated K+ channel SK3 is localized in nerve terminals of excitatory synapses of cultured mouse hippocampal neurons. Eur J Neurosci 17: 721-731.
18. 2+ channel alpha 1C (CaV1.2) to synaptic and extrasynaptic compartments in hippocampal neurons. Eur J Neurosci 19: 2109-2122.
19. Ozaki K, Kadomoto R, Asato K, Tanimura S, Itoh N, Kohno M. 2001. ERK pathway positively regulates the expression of Sprouty genes. Biochem Biophys Res Commun 285: 1084-1088.
20. Ozaki K, Miyazaki S, Tanimura S, Kohno M. 2005. Efficient suppression of FGF-2-induced ERK activation by the cooperative interaction among mammalian Sprouty isoforms. J Cell Sci 118: 5861-5871.
21. Patel MN, Mcnamara JO. 1995. Selective enhancement of axonal branching of cultured dentate gyrus neurons by neurotrophic factors. Neuroscience 69: 763-770.
22. Ramirez JJ, Finklestein SP, Keller J, Abrams W, George MN, Parakh T. 1999. Basic fibroblast growth factor enhances axonal sprouting after cortical injury in rats. Neuroreport 10: 1201-1204.
23. Reuss B, Bohlen und Halbach O. 2003. Fibroblast growth factors and their receptors in the central nervous system. Cell Tissue Res 313: 139-157.
24. Sasaki A, Taketomi T, Wakioka T, Kato R, Yoshimura A. 2001. Identification of a dominant negative mutant of sprouty that potentiates fibroblast growth factor-but not epidermal growth factor-induced ERK activation. J Biol Chem 276: 36804-36808.
25. Sasaki A, Taketomi T, Kato R, Saeki K, Nonami A, Sasaki M, Kuriyama M, Saito N, Shibuya M, Yoshimura A. 2003. Mammalian Sprouty4 suppresses Ras-independent ERK activation by binding to Raf1. Nat Cell Biol 5: 427-432.
26. Schlick B, Flucher BE, Obermair GJ. 2010. Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neurons. Neuroscience 167: 786-798.
27. Suzuki-Hirano A, Sato T, Nakamura H. 2005. Regulation of isthmic Fgf8 signal by sprouty2. Development 132: 257-265.
28. Tefft D, Lee M, Smith S, Crowe DL, Bellusci S, Warburton D. 2002. mSprouty2 inhibits FGF10-activated MAP kinase by differentially binding to upstream target proteins. Am J Physiol Lung Cell Mol Physiol 283: L700-L706.
29. Tefft JD, Lee M, Smith S, Leinwand M, Zhao JS, Bringas P, Crowe DL, Warburton D. 1999. Conserved function of mSpry-2, a murine homolog of Drosophila sprouty, which negatively modulates respiratory organogenesis. Curr Biol 9: 219-222.
30. Thisse B, Thisse C. 2005. Functions and regulations of fibroblast growth factor signaling during embryonic development. Dev Biol 287: 390-402.
31. Tsang M, Dawid IG. 2004. Promotion and attenuation of FGF signaling through the Ras-MAPK pathway. Sci STKE 2004: 1-5.
32. Yusoff P, Lao DH, Ong SH, Wong ESM, Lim J, Lo TL, Leong HF, Fong CW, Guy GR. 2002. Sprouty2 inhibits the Ras/MAP kinase pathway by inhibiting the activation of raf. J Biol Chem 277: 3195-3201.
33. Zhang S, Lin Y, Itäranta P, Yagi A, Vainio S. 2001. Expression of Sprouty genes 1, 2 and 4 during mouse organogenesis. Mech Dev 109: 367-370.