Differential display of genes expressed at the midbrain - hindbrain junction identifies sprouty2: An FGF8-inducible member of a family of intracellular FGF antagonists

Molecular and Cellular Neurosciences

Volumn 15, Issue 1, 2000, Pages 22-35

  Chambers, D ^a   Medhurst, A D ^b   Walsh, F S ^b   Price, J ^b   Mason, I ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; FIBROBLAST GROWTH FACTOR 8;

ARTICLE; DNA DETERMINATION; GENE EXPRESSION; MESENCEPHALON; NEGATIVE FEEDBACK; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REGULATORY MECHANISM; RHOMBENCEPHALON;

EID: 0033950144     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1006/mcne.1999.0801     Document Type: Article

References (44)

1. Bally-Cuif L., Wassef M. Determination events in the nervous system of the vertebrate embryo. Curr. Opin. Genet. Dev. 5:1995;450-458.
2. Bueno D., Skinner J., Abud H., Heath J. K. Spatial and temporal relationships between shh, Fgf4, and Fgf8 gene expression at diverse signalling centres during mouse development. Dev. Dyn. 207:1996;291-299.
3. Casci T., Vinos J., Freeman M. sprouty, an intracellular inhibitor of Ras signalling. Cell. 99:1999;655-665.
4. Chambers, D, and, Mason, I. Expression of sprouty2 during early development of the chick embryo is coincident with known sites of FGF signaling, Mech. Dev, in press.
5. Christen B., Slack J. M. FGF-8 is associated with anteroposterior patterning and limb regeneration in Xenopus. Dev. Biol. 192:1997;455-466.
6. Crossley P. H., Martin G. R. The mouse Fgf8 gene encodes a family of polypeptides and is expressed in a region that directs outgrowth and patterning in the developing embryo. Development. 121:1995;439-451.
7. Crossley P. H., Martinez S., Martin G. R. Midbrain development induced by FGF8 in the chick embryo. Nature. 380:1996;66-68.
8. Freeman M. Reiterative use of the EGF receptor triggers differentiation of all cell types in the Drosophila eye. Cell. 87:1996;651-660.
9. Ghiglione C., Carraway K. L., Amundadottir L. T., Boswell R. E., Perrimon N., Duffy J. B. The transmembrane molecule kekkon 1 acts in a feedback loop to negatively regulate the activity of the Drosophila EGF receptor during oogenesis. Cell. 96:1999;847-856.
10. Hacohen N., Kramer S., Sutherland D., Hiromi Y., Krasnow M. A. Sprouty encodes a novel antagonist of FGF signalling that patterns apical branching of the Drosophila airways. Cell. 92:1998;253-263.
11. Hamburger V., Hamilton H. A series of normal stages in the development of the chick embryo. J. Morphol. 88:1951;49-92.
12. Heikinheimo M., Lawshe A., Shackleford G. M., Wilson D. B., MacArthur C. A. Fgf-8 expression in the post-gastrulation mouse suggests roles in the development of the face, limbs, and central nervous system. Mech. Dev. 48:1994;129-138.
13. Irving C., Mason I. Signalling by FGF8 from the isthmus patterns anterior hindbrain and establishes the anterior limit of Hox gene expression. Development. 2000.
14. Irving C., Mason I. Regeneration of isthmic tissue is the result of a specific and direct interaction between the midbrain and rhombomere 1. Development. 126:1999;3981-3989.
15. Joyner A. L. Engrailed, Wnt and Pax genes regulate mid/hindbrain development. Trends Genet. 12:1996;15-20.
16. Kramer S., Okabe M., Hacohen N., Krasnow M. A., Hiromi Y. sprouty: A common antagonist of FGF and EGF signalling pathways in Drosophila. Development. 126:1999;2515-2525.
17. Leevers S. J. What goes up must come down. Nat. Cell Biol. 1:1999;10-11.
18. Liang P., Pardee A. B. Differential display of eukaryotic messenger RNA by means of the polymerase chain reaction. Science. 257:1992;967-971.
19. Logan C., Wizenmann A., Drescher U., Monschau B., Bonhoeffer F., Lumsden A. Rostral optic tectum acquires caudal characteristics following ectopic engrailed expression. Curr. Biol. 6:1996;1006-1014.
20. Lumsden A., Krumlauf R. Patterning the vertebrate neuraxis. Science. 274:1996;1109-1114.
21. Mahmood R., Bresnick J., Hornbruch A., Mahony K., Morton N., Colquhoun K., Martin P., Lumsden A., Dickson C., Mason I. FGF-8 in the mouse embryo: A role in the initiation and maintenance of limb bud outgrowth. Curr. Biol. 5:1995;797-806.
22. Martinez S., Crossley P. H., Cobos I., Rubenstein J. L., Martin G. R. FGF8 induces formation of an ectopic isthmic organiser and isthmocerebellar development via a repressive effect on Otx2 expression. Development. 126:1999;1189-1200.
23. Mason I. Chick embryos: Incubation and isolation. Sharpe P. T., Mason I. Methods in Molecular Biology. 1999;Humana Press, Totowa.
24. Mathieu-Daude F., Cheng R., Welsh J., McClelland M. Screening of differentially amplified cDNA products from RNA arbitrarily primed PCR fingerprints using single strand conformation polymorphism (SSCP) gels. Nucleic Acids Res. 24:1996;1504-1507.
25. McKay I. J., Lewis J., Lumsden A. The role of FGF3 in early inner ear development: An analysis in normal and kreisler mutant mice. Dev. Biol. 174:1996;370-378.
26. Medhurst A. D., Chambers D., Gray J., Davis J. B., Shale J. A., Mason I., Jenner P., Newton R. A. Practical aspects of the experimental design for differential display of transcripts obtained from complex tissues. Methods in Differential Gene Screening. 1999;Oxford Univ. Press, London.
27. Meyers E. N., Lewandoski M., Martin G. R. An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination. Nat. Genet. 18:1998;136-141.
28. Muhr J., Jessel T. M., Edlund T. Assignment of early caudal identity to neural plate cells by a signal from caudal paraxial mesoderm. Neuron. 19:1997;487-502.
29. Nieto M. A., Sargent M. G., Wilkinson D. G., Cooke J. Control of cell behaviour during vertebrate development by Slug, a zinc finger gene. Science. 264:1994;835-839.
30. Ohuchi H., Yoshioka H., Tanaka A., Kawakami Y., Nohno T., Noji S. Involvement of androgen induced growth factor (FGF-8) gene in mouse embryogenesis and morphogenesis. Biochem. Biophys. Res. Commun. 204:1994;882-888.
31. Perrimon N., McMahon A. P. Negative feedback mechanisms and their roles during pattern formation. Cell. 97:1999;13-16.
32. Picker A., Brennan C., Reifers F., Clarke J. D., Holder N., Brand M. Requirement for the zebrafish mid-hindbrain boundary in midbrain polarisation, mapping and confinement of the retinotectal projection. Development. 126:1999;2967-2978.
33. Reifers F., Bohli H., Walsh E., Crossley P., Stanier D., Brand M. Fgf8 is mutated in zebrafish acerebellar (ace) mutants and is required for maintenance of mid/hindbrain boundary development and somitogenesis. Development. 125:1998;2381-2395.
34. Ruiz I Altaba A. Pattern formation in the vertebrate neural plate. Trends Neurosci. 17:1994;233-243.
35. Ruiz I Altaba A. Neural patterning. Deconstructing the organiser. Nature. 391:1998;748-749.
36. Sambrook J., Fritsch T., Maniatis T. Molecular Cloning: A Laboratory Manual. 1989;Cold Spring Harbor Laboratory Press, Cold Spring Harbor.
37. Shamim H., Mahmood R., Logan C., Doherty P., Lumsden A., Mason I. Sequential roles for Fgf4, En1 and Fgf8 in specification and regionalisation of the midbrain. Development. 126:1999;945-949.
38. Sheikh H., Mason I. Polarising activity of FGF-8 in the avian midbrain. Int. J. Dev. Biol. 1996;117-118.
39. Storey K. G., Goriely A., Sargent C. M., Brown J. M., Burns H. D., Abud H. M., Heath J. K. Early posterior neural tissue is induced by FGF in the chick embryo. Development. 125:1998;473-484.
40. Tefft J. D., Lee M., Smith S., Leinward M., Zhoa J., Bringas P., Crowe D. L., Warburton D. Conserved function of mSpry-2, a murine homolog of Drosophila sprouty, which negatively modulates respiratory organogenesis. Curr. Biol. 9:1999;219-222.
41. Vogel A., Rodriguez C., Izpisua-Belmonte J. C. Involvement of FGF-8 in initiation, outgrowth and patterning of the vertebrate limb. Development. 122:1996;1737-1750.
42. Walshe J., Mason I. Expression of FGFR1, FGFR2 and FGFR3 during early neural development in the chick. Mech. Dev. 1999.
43. Wassef M., Joyner A. L. Early mesencephalon/metencephalon patterning and development of the cerebellum. Perspect. Dev. Neurobiol. 5:1997;3-16.
44. Wingate R. J. T., Hatten M. E. The role of the rhombic lip in avian cerebellum development. Development. 126:1999;4395-4404.