Erk pathway positively regulates the expression of sprouty genes

Biochemical and Biophysical Research Communications

Volumn 285, Issue 5, 2001, Pages 1084-1088

  Ozaki, Keiichi ^a   Kadomoto, Ryoji ^a   Asato, Keita ^a   Tanimura, Susumu ^a   Itoh, Nobuyuki ^b   Kohno, Michiaki ^a  

^a NAGASAKI UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

ERK; MAP kinase; Negative feedback.; Receptor tyrosine kinase; Sprouty

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PHORBOL 12 ACETATE 13 MYRISTATE; RAF PROTEIN;

ARTICLE; CORRELATION FUNCTION; DROSOPHILA; ENZYME ANALYSIS; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; NEGATIVE FEEDBACK; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 0034801558     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2001.5295     Document Type: Article

References (22)

1. Sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways
2. Sprouty, an intracellular inhibitor of Ras signaling
3. Sprouty: A common antagonist of FGF and EGF signaling pathways in Drosophila
4. Sprouty is a general inhibitor of receptor tyrosine kinase signaling
5. Cloning and expression pattern of a mouse homologue of Drosophila sprouty in the mouse embryo
6. Mammalian Sprouty-1 and -2 are membrane-anchored phosphoprotein inhibitors of growth factor signaling in endothelial cells
7. Vertebrate Sprouty genes are induced by FGF signaling and can cause chondrodysplasia when overexpressed
8. Conserved function of mSpry-2, a murine homolog of Drosophila sprouty, which negatively modulates respiratory organogenesis
9. Evidence that SPROUTY2 functions as an inhibitor of mouse embryonic lung growth and morphogenesis
10. Evidence for direct interaction between Sprouty and Cb1
11. Inhibition of angiogenesis by a mouse sprouty protein
12. Human SPRY2 inhibits FGF2 signalling by a secreted factor
13. A synthetic inhibitor of the mitogen-activated protein kinase cascade
14. Activation of the 41/43 kDa mitogen-activated protein kinase signaling pathway is required for hepatocyte growth factor-induced cell scattering
15. Identification of a novel inhibitor of mitogen-activated protein kinase kinase
16. A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)
17. Conditinal transformation of cells and rapid activation of the mitogen-activated protein kinase cascade by an estradiopl-dependent human raf-1 protein kinase
18. Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors
19. Ploidy of embryonic fibroblasts during in vitro aging
20. Cell type-specific modulation of cell growth by transforming growth factor b1 does not correlate with mitogen-activated protein kinase activation
21. SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1
22. Characterization of a newly derived human sarcoma cell line (HT-1080)