Sprouty2 down-regulation promotes axon growth by adult sensory neurons

Molecular and Cellular Neuroscience

Volumn 42, Issue 4, 2009, Pages 328-340

  Hausott, Barbara ^a   Vallant, Natalie ^a   Auer, Maria ^a   Yang, Lin ^a,c   Dai, Fangping ^b   Brand Saberi, Beate ^b,d   Klimaschewski, Lars ^a  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^b UNIVERSITY OF FREIBURG   (Germany)

^c CAPITAL MEDICAL UNIVERSITY   (China)

^d RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR 2; ISOPROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; NERVE GROWTH FACTOR; RAF PROTEIN; RAS PROTEIN; SMALL INTERFERING RNA; SPROUTY 1 PROTEIN; SPROUTY 2 PROTEIN; SPROUTY 3 PROTEIN; SPROUTY 4 PROTEIN; SPROUTY PROTEIN; UNCLASSIFIED DRUG;

ADULT ANIMAL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ELONGATION; CELL STRAIN; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME REGULATION; FEMALE; NEGATIVE FEEDBACK; NERVE FIBER REGENERATION; NERVE GROWTH; NERVE LESION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; RAT; SENSORY NERVE CELL; SIGNAL TRANSDUCTION; SPINAL GANGLION;

ANIMALS; AXONS; DOWN-REGULATION; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; FIBROBLAST GROWTH FACTOR 2; GANGLIA, SPINAL; MEMBRANE PROTEINS; MICE; NERVE TISSUE PROTEINS; NIH 3T3 CELLS; PC12 CELLS; PROTEIN ISOFORMS; RAF KINASES; RAS PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, FIBROBLAST GROWTH FACTOR; RNA, SMALL INTERFERING; SENSORY RECEPTOR CELLS; SIGNAL TRANSDUCTION;

EID: 70350749418     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mcn.2009.08.005     Document Type: Article

References (36)

1. Atwal J.K., Massie B., Miller F.D., and Kaplan D.R. The TrkB-Shc site signals neuronal survival and local axon growth via MEK and PI3-kinase. Neuron 27 (2000) 265-277
2. Baird A. Fibroblast growth factors: activities and significance of non-neurotrophin neurotrophic factors. Curr. Opin. Neurobiol. 4 (1994) 78-86
3. Cowley S., Paterson H., Kemp P., and Marshall C.J. Activation of Map kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH3T3 cells. Cell 77 (1994) 841-852
4. Dikic I., and Giordano S. Negative receptor signalling. Curr. Opin. Cell Biol. 15 (2003) 128-135
5. Ford-Perriss M., Abud H., and Murphy M. Fibroblast growth factors in the developing central nervous system. Clin. Exp. Pharmacol. Physiol. 28 (2001) 493-503
6. Gross I., Bassit B., Benezra M., and Licht J.D. Mammalian Sprouty proteins inhibit cell growth and differentiation by preventing Ras activation. J. Biol. Chem. 276 (2001) 46460-46468
7. Gross I., Armant O., Benosman S., de Aguilar J.L.G., Freund J.N., Kedinger M., Licht J.D., Gaiddon C., and Loeffler J.P. Sprouty2 inhibits BDNF-induced signaling and modulates neuronal differentiation and survival. Cell Death Differ. 14 (2007) 1802-1812
8. Grothe C., Haastert K., and Jungnickel J. Physiological function and putative therapeutic impact of the FGF-2 system in peripheral nerve regeneration - lessons from in vivo studies in mice and rats. Brain Res. Rev. 51 (2006) 293-299
9. Guy G.R., Wong E.S.M., Yusoff P., Chandramouli S., Lo T.L., Lim J., and Fong C.W. Sprouty: how does the branch manager work?. J. Cell Sci. 116 (2003) 3061-3068
10. Hacohen N., Kramer S., Sutherland D., Hiromi Y., and Krasnow M.A. Sprouty encodes a novel antagonist of FGF signaling that patterns apical branching of the Drosophila airways. Cell 92 (1998) 253-263
11. Hanafusa H., Torii S., Yasunaga T., and Nishida E. Sprouty1 and Sprouty2 provide a control mechanism for the Ras/MAPK signalling pathway. Nat. Cell Biol. 4 (2002) 850-858
12. Hausott B., Schlick B., Vallant N., Dorn R., and Klimaschewski L. Promotion of neurite outgrowth by fibroblast growth factor receptor 1 overexpression and lysosomal inhibition of receptor degradation in pheochromocytoma cells and adult sensory neurons. Neuroscience 153 (2008) 461-473
13. Impagnatiello M.A., Weitzer S., Gannon G., Compagni A., Cotten M., and Christofori G. Mammalian Sprouty-1 and-2 are membrane-anchored phosphoprotein inhibitors of growth factor signaling in endothelial cells. J. Cell Biol. 152 (2001) 1087-1098
14. Ishida M., Ichihara M., Mii S., Jijiwa M., Asai N., Enomoto A., Kato T., Majima A., Ping J., Murakumo Y., and Takahashi M. Sprouty2 regulates growth and differentiation of human neuroblastoma cells through RET tyrosine kinase. Cancer Sci. 98 (2007) 815-821
15. Klesse L.J., Meyers K.A., Marshall C.J., and Parada L.F. Nerve growth factor induces survival and differentiation through two distinct signaling cascades in PC12 cells. Oncogene 18 (1999) 2055-2068
16. Klimaschewski L., Nindl W., Feurle J., Kavakebi P., and Kostron H. Basic fibroblast growth factor isoforms promote axonal elongation and branching of adult sensory neurons in vitro. Neuroscience 126 (2004) 347-353
17. Lim J., Wong E.S.M., Ong S.H., Yusoff P., Low B.C., and Guy G.R. Sprouty proteins are targeted to membrane ruffles upon growth factor receptor tyrosine kinase activation - identification of a novel translocation domain. J. Biol. Chem. 275 (2000) 32837-32845
18. Markus A., Zhong J., and Snider W.D. Raf and Akt mediate distinct aspects of sensory axon growth. Neuron 35 (2002) 65-76
19. Mason I. Initiation to end point: the multiple roles of fibroblast growth factors in neural development. Nat. Rev., Neurosci. 8 (2007) 583-596
20. Mason J.M., Morrison D.J., Bassit B., Dimri M., Band H., Licht J.D., and Gross I. Tyrosine phosphorylation of sprouty proteins regulates their ability to inhibit growth factor signaling: a dual feedback loop. Mol. Biol. Cell 15 (2004) 2176-2188
21. Mason J.M., Morrison D.J., Basson M.A., and Licht J.D. Sprouty proteins: multifaceted negative-feed back regulators of receptor tyrosine kinase signaling. Trends Cell Biol. 16 (2006) 45-54
22. Minowada G., Jarvis L.A., Chi C.L., Neubuser A., Sun X., Hacohen N., Krasnow M.A., and Martin G.R. Vertebrate Sprouty genes are induced by FGF signaling and can cause chondrodysplasia when overexpressed. Development 126 (1999) 4465-4475
23. Ozaki K., Kadomoto R., Asato K., Tanimura S., Itoh N., and Kohno M. ERK pathway positively regulates the expression of Sprouty genes. Biochem. Biophys. Res. Commun. 285 (2001) 1084-1088
24. Ozaki K., Miyazaki S., Tanimura S., and Kohno M. Efficient suppression of FGF-2-induced ERK activation by the cooperative interaction among mammalian Sprouty isoforms. J. Cell Sci. 118 (2005) 5861-5871
25. Perlson E., Hanz S., Ben Yaakov K., Segal-Ruder Y., Seger R., and Fainzilber M. Vimentin-dependent spatial translocation of an activated MAP kinase in injured nerve. Neuron 45 (2005) 715-726
26. Reuss B., and von Bohlen und Halbach O. Fibroblast growth factors and their receptors in the central nervous system. Cell Tissue Res. 313 (2003) 139-157
27. Rubin C., Litvak V., Medvedovsky H., Zwang Y., Lev S., and Yarden Y. Sprouty fine-tunes EGF signaling through interlinked positive and negative feedback loops. Curr. Biol. 13 (2003) 297-307
28. Sasaki A., Taketomi T., Wakioka T., Kato R., and Yoshimura A. Identification of a dominant negative mutant of sprouty that potentiates fibroblast growth factor-but not epidermal growth factor-induced ERK activation. J. Biol. Chem. 276 (2001) 36804-36808
29. Sasaki A., Taketomi T., Kato R., Saeki K., Nonami A., Sasaki M., Kuriyama M., Saito N., Shibuya M., and Yoshimura A. Mammalian Sprouty4 suppresses Ras-independent ERK activation by binding to Raf1. Nat. Cell Biol. 5 (2003) 427-432
30. Tefft D., Lee M., Smith S., Crowe D.L., Bellusci S., and Warburton D. mSprouty2 inhibits FGF10-activated MAP kinase by differentially binding to upstream target proteins. Am. J. Physiol., Lung Cell. Mol. Physiol. 283 (2002) L700-L706
31. Tsang M., and Dawid I.G. Promotion and attenuation of fgf signaling through the Ras-MAPK pathway. Sci. STKE (2004) 1-5
32. Wood K.W., Qi H.Q., Darcangelo G., Armstrong R.C., Roberts T.M., and Halegoua S. The cytoplasmic Raf oncogene induces a neuronal phenotype in PC12 cells - a potential role for cellular Raf kinases in neuronal growth-factor signal-transduction. Proc. Natl. Acad. Sci. USA 90 (1993) 5016-5020
33. Yigzaw Y., Cartin L., Pierre S., Scholich K., and Patel T.B. The C terminus of sprouty is important for modulation of cellular migration and proliferation. J. Biol. Chem. 276 (2001) 22742-22747
34. Yusoff P., Lao D.H., Ong S.H., Wong E.S.M., Lim J., Lo T.L., Leong H.F., Fong C.W., and Guy G.R. Sprouty2 inhibits the Ras/MAP kinase pathway by inhibiting the activation of raf. J. Biol. Chem. 277 (2002) 3195-3201
35. Zhong J., Li X.Y., McNamee C., Chen A.P., Baccarini M., and Snider W.D. Raf kinase signaling functions in sensory neuron differentiation and axon growth in vivo. Nat. Neurosci. 10 (2007) 598-607
36. Zhou F.Q., and Snider W.D. Intracellular control of developmental and regenerative axon growth. Philos. Trans. R. Soc. Lond., B Biol. Sci. 361 (2006) 1575-1592