-
2
-
-
77956407766
-
Integrating evolutionary and functional approaches to infer adaptation at specific loci
-
Storz JF, Wheat CW (2010) Integrating evolutionary and functional approaches to infer adaptation at specific loci, Evolution 64: 2489–2509
-
(2010)
Evolution
, vol.64
, pp. 2489-2509
-
-
Storz, JF1
Wheat, CW2
-
4
-
-
0024041395
-
Quantitative analysis of RNA produced by slow and fast alleles of Adh in Drosophila melanogaster
-
Laurie CC, Stam LF (1988) Quantitative analysis of RNA produced by slow and fast alleles of Adh in Drosophila melanogaster, Proc Natl Acad Sci USA 85:5161–5165
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 5161-5165
-
-
Laurie, CC1
Stam, LF2
-
5
-
-
0024389204
-
Molecular basis of evolutionary adaptation at the lactate dehydrogenase-B locus in the fish Fundulus heteroclitus
-
Crawford DL, Powers DA (1989) Molecular basis of evolutionary adaptation at the lactate dehydrogenase-B locus in the fish Fundulus heteroclitus. Proc Natl Acad Sci USA 86: 9365–9369
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 9365-9369
-
-
Crawford, DL1
Powers, DA2
-
6
-
-
0016738957
-
The contribution of ecological genetics to evolutionary theory: detecting the direct effects of natural selection at particular polymorphic loci
-
Clarke B (1975) The contribution of ecological genetics to evolutionary theory: detecting the direct effects of natural selection at particular polymorphic loci. Genetics 79:101–113
-
(1975)
Genetics
, vol.79
, pp. 101-113
-
-
Clarke, B1
-
7
-
-
0006499582
-
Enzyme polymorphism and natural selection
-
Nei M, Koehn RK, (eds) Sinauer, Sunderland, MA
-
Koehn RK, Zera AJ, Hall JG (1983) Enzyme polymorphism and natural selection. In: Nei M, Koehn RK, (eds.) Evolution of genes and proteins, Sinauer, Sunderland, MA
-
(1983)
Evolution of genes and proteins
-
-
Koehn, RK1
Zera, AJ2
Hall, JG3
-
8
-
-
0025639253
-
Enzyme activity and fitness: evolution in solution
-
Dykhuizen DE, Dean AM (1990) Enzyme activity and fitness: evolution in solution. Trends Ecol Evol 5:257–262
-
(1990)
Trends Ecol Evol
, vol.5
, pp. 257-262
-
-
Dykhuizen, DE1
Dean, AM2
-
9
-
-
0034500083
-
Molecular-functional studies of adaptive genetic variation in prokaryotes and eukaryotes
-
Watt WB, Dean AM (2000) Molecular-functional studies of adaptive genetic variation in prokaryotes and eukaryotes. Ann Rev Genet 34:593–622
-
(2000)
Ann Rev Genet
, vol.34
, pp. 593-622
-
-
Watt, WB1
Dean, AM2
-
10
-
-
34548018528
-
Mechanistic approaches to the study of evolution: the functional synthesis
-
Dean AM, Thornton JW (2007) Mechanistic approaches to the study of evolution: the functional synthesis. Nat Rev Genet 8:675–688
-
(2007)
Nat Rev Genet
, vol.8
, pp. 675-688
-
-
Dean, AM1
Thornton, JW2
-
11
-
-
84887972179
-
Experimental evolution from the bottom up
-
Garland T, Rose MR (eds) Univ Calif Press, Berkeley
-
Dykhuizen DE, Dean AM (2009) Experimental evolution from the bottom up. In: Garland T, Rose MR (eds.) Experimental evolution: concepts, methods, and applications of selection experiments. Univ Calif Press, Berkeley
-
(2009)
Experimental evolution: concepts, methods, and applications of selection experiments
-
-
Dykhuizen, DE1
Dean, AM2
-
12
-
-
0018527496
-
Molecular democracy: who shares the controls?
-
Kacser H, Burnes JA (1979) Molecular democracy: who shares the controls? Trans Biochem Soc 7:1149–1160
-
(1979)
Trans Biochem Soc
, vol.7
, pp. 1149-1160
-
-
Kacser, H1
Burnes, JA2
-
13
-
-
0019869334
-
The molecular basis of dominance
-
Kacser H, Burnes JA (1981) The molecular basis of dominance. Genetics 97:639–666
-
(1981)
Genetics
, vol.97
, pp. 639-666
-
-
Kacser, H1
Burnes, JA2
-
14
-
-
33645666942
-
Darwinian evolution can follow only very few mutational paths to fitter proteins
-
Weinreich DM, Delaney NF, DePristo MA et al (2006) Darwinian evolution can follow only very few mutational paths to fitter proteins. Science 312:111–114
-
(2006)
Science
, vol.312
, pp. 111-114
-
-
Weinreich, DM1
Delaney, NF2
DePristo, MA3
-
15
-
-
73349085245
-
Temporal constraints on the incorporation of regulatory mutants in evolutionary pathways
-
Brown KM, DePristo MA, Weinreich DM et al (2009) Temporal constraints on the incorporation of regulatory mutants in evolutionary pathways. Mol Biol Evol 26:2455–2462
-
(2009)
Mol Biol Evol
, vol.26
, pp. 2455-2462
-
-
Brown, KM1
DePristo, MA2
Weinreich, DM3
-
16
-
-
0027745311
-
Acquisition of new metabolic activities by microbial populations
-
Abelson JN, Simon MI, Zimmer EA et al (eds) Academic Press Inc, San Diego
-
Hall BG, Hauer B (1993) Acquisition of new metabolic activities by microbial populations. In: Abelson JN, Simon MI, Zimmer EA et al (eds.) Molecular evolution: producing the biochemical data. Academic Press Inc, San Diego
-
(1993)
Molecular evolution: producing the biochemical data
-
-
Hall, BG1
Hauer, B2
-
17
-
-
76649130556
-
Molecular and functional basis of phenotypic convergence in white lizards at White Sands
-
Rosenblum EB, Rompler H, Schoneberg T et al (2009) Molecular and functional basis of phenotypic convergence in white lizards at White Sands. Proc Natl Acad Sci USA 107: 2113–2117
-
(2009)
Proc Natl Acad Sci USA
, vol.107
, pp. 2113-2117
-
-
Rosenblum, EB1
Rompler, H2
Schoneberg, T3
-
18
-
-
0033369552
-
Analysis of selection on enzyme polymorphisms
-
Eanes WF (1999) Analysis of selection on enzyme polymorphisms. Ann Rev Ecol Systemat 30:301–326
-
(1999)
Ann Rev Ecol Systemat
, vol.30
, pp. 301-326
-
-
Eanes, WF1
-
19
-
-
0024652684
-
Allozymes of glucose-6-phosphate isomerase differentially modulate pentose-shunt metabolism in the sea anemone Metridium senile
-
Zamer WE, Hoffman RJ (1989) Allozymes of glucose-6-phosphate isomerase differentially modulate pentose-shunt metabolism in the sea anemone Metridium senile, Proc Natl Acad Sci USA 86:2737–2741
-
(1989)
Proc Natl Acad Sci USA
, vol.86
, pp. 2737-2741
-
-
Zamer, WE1
Hoffman, RJ2
-
22
-
-
8544270088
-
Single-locus latitudinal clines and relationship to temperate adaptation in metabolic genes and derived alleles in Drosophila melanogaster
-
Sezgin E, Duvernell D, Matzkin LM et al (2004) Single-locus latitudinal clines and relationship to temperate adaptation in metabolic genes and derived alleles in Drosophila melanogaster. Genetics 168:923–931
-
(2004)
Genetics
, vol.168
, pp. 923-931
-
-
Sezgin, E1
Duvernell, D2
Matzkin, LM3
-
23
-
-
0021801034
-
F from the fruitfly Drosophila melanogaster: an enzymatic rate assay to determine the active-site concentration
-
F from the fruitfly Drosophila melanogaster: an enzymatic rate assay to determine the active-site concentration. Biochem Genet 23:205–216
-
(1985)
Biochem Genet
, vol.23
, pp. 205-216
-
-
Winberg, JO1
Hovik, R2
McKinley-McKee, JS3
-
24
-
-
0026759695
-
Direct measurement of in vivo flux differences between electrophoretic variants of G6PD in Drosophila melanogaster
-
Labate J, Eanes WF (1992) Direct measurement of in vivo flux differences between electrophoretic variants of G6PD in Drosophila melanogaster. Genetics 132:783–787
-
(1992)
Genetics
, vol.132
, pp. 783-787
-
-
Labate, J1
Eanes, WF2
-
25
-
-
0026053091
-
Associations between DNA sequence variation and variation in expression of the Adh gene in natural populations of Drosophila melanogaster
-
Laurie CC, Bridgham J, Choudhary M (1991) Associations between DNA sequence variation and variation in expression of the Adh gene in natural populations of Drosophila melanogaster. Genetics 129:489–499
-
(1991)
Genetics
, vol.129
, pp. 489-499
-
-
Laurie, CC1
Bridgham, J2
Choudhary, M3
-
26
-
-
0028031431
-
The effect of an intronic polymorphism on alcohol dehydrogenase expression in Drosophila melanogaster
-
Laurie CC, Stam LF (1994) The effect of an intronic polymorphism on alcohol dehydrogenase expression in Drosophila melanogaster. Genetics 138:379–385
-
(1994)
Genetics
, vol.138
, pp. 379-385
-
-
Laurie, CC1
Stam, LF2
-
27
-
-
0030453209
-
Molecular dissection of a major gene effect on a quantitative trait: the level of alcohol dehydrogenase expression in Drosophila melanogaster
-
Stam LF, Laurie CC (1996) Molecular dissection of a major gene effect on a quantitative trait: the level of alcohol dehydrogenase expression in Drosophila melanogaster. Genetics 144:1559–1564
-
(1996)
Genetics
, vol.144
, pp. 1559-1564
-
-
Stam, LF1
Laurie, CC2
-
28
-
-
0020804075
-
Biochemical and molecular analysis of naturally occurring Adh variants in Drosophila melanogaster
-
Anderson SM, McDonald JF (1983) Biochemical and molecular analysis of naturally occurring Adh variants in Drosophila melanogaster. Proc Natl Acad Sci USA 80:4798–4802
-
(1983)
Proc Natl Acad Sci USA
, vol.80
, pp. 4798-4802
-
-
Anderson, SM1
McDonald, JF2
-
29
-
-
0026760697
-
Evolutionary adaptation to different thermal environments via transcriptional regulation
-
Crawford DL, Powers DA (1992) Evolutionary adaptation to different thermal environments via transcriptional regulation. Mol Biol Evol 9:806–813
-
(1992)
Mol Biol Evol
, vol.9
, pp. 806-813
-
-
Crawford, DL1
Powers, DA2
-
30
-
-
78651309764
-
Intermediary metabolism and the biochemical-molecular basis of life history variation and trade-offs in two insect models
-
Flatt T, Heywood A, (eds) Oxford Univ Press, New York
-
Zera AJ, Harshman LG (2011) Intermediary metabolism and the biochemical-molecular basis of life history variation and trade-offs in two insect models. In: Flatt T, Heywood A, (eds.) Molecular mechanisms of life-history evolution. Oxford Univ Press, New York
-
(2011)
Molecular mechanisms of life-history evolution
-
-
Zera, AJ1
Harshman, LG2
-
33
-
-
78651313713
-
Molecular population genetics and selection in the glycolytic pathway
-
Eanes WF (2011) Molecular population genetics and selection in the glycolytic pathway. J Exp Biol 214:165–171
-
(2011)
J Exp Biol
, vol.214
, pp. 165-171
-
-
Eanes, WF1
-
34
-
-
0033048066
-
Moonlighting proteins
-
Jeffery C (1999) Moonlighting proteins. Trends Biochem Sci 24:8–11
-
(1999)
Trends Biochem Sci
, vol.24
, pp. 8-11
-
-
Jeffery, C1
-
36
-
-
0018427161
-
Genetic variation and relative catalytic efficiencies: lactate dehydrogenase-B allozymes of Fundulus heteroclitus
-
Place AR, Powers DA (1979) Genetic variation and relative catalytic efficiencies: lactate dehydrogenase-B allozymes of Fundulus heteroclitus. Proc Natl Acad Sci USA 76: 2354–2358
-
(1979)
Proc Natl Acad Sci USA
, vol.76
, pp. 2354-2358
-
-
Place, AR1
Powers, DA2
-
37
-
-
0022382056
-
Temperature-related kinetic differentiation of glucosephosphate isomerase alleloenzymes isolated from the blue mussel
-
Hall JG (1985) Temperature-related kinetic differentiation of glucosephosphate isomerase alleloenzymes isolated from the blue mussel, Mytilus edulis Biochem Genet 23:705–728
-
(1985)
Mytilus edulis Biochem Genet
, vol.23
, pp. 705-728
-
-
Hall, JG1
-
38
-
-
0025310949
-
Comparison of in vitro and in vivo activities associated with G6PD allozyme polymorphims in Drosophila melanogaster
-
Eanes W, Katona L, Longtine M (1990) Comparison of in vitro and in vivo activities associated with G6PD allozyme polymorphims in Drosophila melanogaster. Genetics 125: 845–853
-
(1990)
Genetics
, vol.125
, pp. 845-853
-
-
Eanes, W1
Katona, L2
Longtine, M3
-
39
-
-
0023673875
-
Studies of esterase 6 in Drosophila melanogaster. XVIII. Biochemical differences between the slow and fast allozymes
-
White MW, Mane SD, Richmond RC (1988) Studies of esterase 6 in Drosophila melanogaster. XVIII. Biochemical differences between the slow and fast allozymes. Mol Biol Evol 5:41–62
-
(1988)
Mol Biol Evol
, vol.5
, pp. 41-62
-
-
White, MW1
Mane, SD2
Richmond, RC3
-
40
-
-
0008020354
-
The evolution of catalytic efficiency and adaptive inference from steady-state kinetic data
-
Hall JG, Koehn RK (1983) The evolution of catalytic efficiency and adaptive inference from steady-state kinetic data. Evol Biol 16:53–96
-
(1983)
Evol Biol
, vol.16
, pp. 53-96
-
-
Hall, JG1
Koehn, RK2
-
41
-
-
0001432824
-
Adaptation at specific loci. II. Demographic and biochemical elements in the maintenance of the Colias PGI polymorphism
-
Watt WB (1983) Adaptation at specific loci. II. Demographic and biochemical elements in the maintenance of the Colias PGI polymorphism. Genetics 103:691–724
-
(1983)
Genetics
, vol.103
, pp. 691-724
-
-
Watt, WB1
-
42
-
-
0029925676
-
Adaptation at specific loci. VI. Divergence vs. parallelism of polymorphic allozymes in molecular function and fitness component effects among Colias species (Lepidoptera; Pieridae)
-
Watt WB, Donohue K, Carter PA (1996) Adaptation at specific loci. VI. Divergence vs. parallelism of polymorphic allozymes in molecular function and fitness component effects among Colias species (Lepidoptera; Pieridae). Mol Biol Evol 13:699–709
-
(1996)
Mol Biol Evol
, vol.13
, pp. 699-709
-
-
Watt, WB1
Donohue, K2
Carter, PA3
-
43
-
-
77957790010
-
The Drosophila alcohol dehydrogenase gene-enzyme system
-
Chambers GK (1988) The Drosophila alcohol dehydrogenase gene-enzyme system, Advances Genet 25:39–107
-
(1988)
Advances Genet
, vol.25
, pp. 39-107
-
-
Chambers, GK1
-
44
-
-
33144478352
-
From DNA to fitness differences: sequences and structures of adaptive variants of Colias phosphoglucose isomerase (PGI)
-
Wheat CW, Watt WB, Pollock DD et al (2006) From DNA to fitness differences: sequences and structures of adaptive variants of Colias phosphoglucose isomerase (PGI), Mol Biol Evol 23:499–512
-
(2006)
Mol Biol Evol
, vol.23
, pp. 499-512
-
-
Wheat, CW1
Watt, WB2
Pollock, DD3
-
45
-
-
0034805082
-
The functional impact of Pgm amino acid polymorphism on glycogen content in Drosophila melanogaster
-
Verrelli BC, Eanes WF (2001) The functional impact of Pgm amino acid polymorphism on glycogen content in Drosophila melanogaster. Genetics 159:201–210
-
(2001)
Genetics
, vol.159
, pp. 201-210
-
-
Verrelli, BC1
Eanes, WF2
-
46
-
-
0035051292
-
Clinal variation for amino acid polymorphisms at the Pgm locus in Drosophila melanogaster
-
Verrelli BC, Eanes WF (2001) Clinal variation for amino acid polymorphisms at the Pgm locus in Drosophila melanogaster. Genetics 157:1649–1663
-
(2001)
Genetics
, vol.157
, pp. 1649-1663
-
-
Verrelli, BC1
Eanes, WF2
-
47
-
-
0026349634
-
Genetic mechanisms for adapting to a changing environment
-
Powers DA, Lauerman T, Crawford D et al (1991) Genetic mechanisms for adapting to a changing environment. Ann Rev Genet 25:629–659
-
(1991)
Ann Rev Genet
, vol.25
, pp. 629-659
-
-
Powers, DA1
Lauerman, T2
Crawford, D3
-
48
-
-
0037396292
-
Enzymes with extra talents: moonlighting functions and catalytic promiscuity
-
Copley S (2003) Enzymes with extra talents: moonlighting functions and catalytic promiscuity. Curr Opin Chem Biol 7:265–272
-
(2003)
Curr Opin Chem Biol
, vol.7
, pp. 265-272
-
-
Copley, S1
-
49
-
-
77954856208
-
Evolutionary and functional properties of a two-locus b-globin polymorphism in Indian house mice
-
Runck AM, Weber RE, Fago A et al (2010) Evolutionary and functional properties of a two-locus b-globin polymorphism in Indian house mice. Genetics 184:1121–1131
-
(2010)
Genetics
, vol.184
, pp. 1121-1131
-
-
Runck, AM1
Weber, RE2
Fago, A3
-
50
-
-
0021341536
-
Viability interactions, in vivo activity and the G6PD polymorphism in Drosophila melanogaster
-
Eanes WF (1984) Viability interactions, in vivo activity and the G6PD polymorphism in Drosophila melanogaster. Genetics 106: 95–107
-
(1984)
Genetics
, vol.106
, pp. 95-107
-
-
Eanes, WF1
-
51
-
-
0019585914
-
Evidence for biochemical and physiological differences between enzyme genotypes in Drosophila melanogaster
-
Cavener DR, Clegg MT (1981) Evidence for biochemical and physiological differences between enzyme genotypes in Drosophila melanogaster. Proc Natl Acad Sci USA 78: 11666–11670
-
(1981)
Proc Natl Acad Sci USA
, vol.78
, pp. 11666-11670
-
-
Cavener, DR1
Clegg, MT2
-
52
-
-
0021035271
-
Enzyme variation, metabolic flux and fitness: alcohol dehydrogenase in Drosophila melanogaster
-
Middleton RJ, Kacser H (1983) Enzyme variation, metabolic flux and fitness: alcohol dehydrogenase in Drosophila melanogaster. Genetics 105:633–650
-
(1983)
Genetics
, vol.105
, pp. 633-650
-
-
Middleton, RJ1
Kacser, H2
-
53
-
-
0027934147
-
Drosophila alcohol dehydrogenase polymorphism and carbon-13 fluxes: opportunities for epistasis and natural selection
-
Freriksen A, de Ruiter BLA, Scharloo W et al (1994) Drosophila alcohol dehydrogenase polymorphism and carbon-13 fluxes: opportunities for epistasis and natural selection. Genetics 137:1071–1078
-
(1994)
Genetics
, vol.137
, pp. 1071-1078
-
-
Freriksen, A1
de Ruiter, BLA2
Scharloo, W3
-
54
-
-
78651345336
-
Microevolution of intermediary metabolism: evolutionary genetics meets metabolic biochemistry
-
Zera AJ (2011) Microevolution of intermediary metabolism: evolutionary genetics meets metabolic biochemistry. J Exp Biol 214:179–190
-
(2011)
J Exp Biol
, vol.214
, pp. 179-190
-
-
Zera, AJ1
-
55
-
-
7944231804
-
Functional adaptation and its molecular basis in vertebrate hemoglobins, neuroglobins and cytoglobins
-
Weber RE, Fago A (2004) Functional adaptation and its molecular basis in vertebrate hemoglobins, neuroglobins and cytoglobins. Respir Physiol Neurobiol 144:141–159
-
(2004)
Respir Physiol Neurobiol
, vol.144
, pp. 141-159
-
-
Weber, RE1
Fago, A2
-
56
-
-
34548671665
-
High-altitude adaptations in vertebrate hemoglobins
-
Weber R E (2007) High-altitude adaptations in vertebrate hemoglobins. Respir Physiol Neurobiol 158:132–142
-
(2007)
Respir Physiol Neurobiol
, vol.158
, pp. 132-142
-
-
Weber, R E1
-
57
-
-
46249085097
-
Mechanisms of hemoglobin adaptation to high-altitude hypoxia
-
Storz JF, Moriyama H (2008) Mechanisms of hemoglobin adaptation to high-altitude hypoxia. High Alt Med Biol 9:148–157
-
(2008)
High Alt Med Biol
, vol.9
, pp. 148-157
-
-
Storz, JF1
Moriyama, H2
-
58
-
-
78650071722
-
Phenotypic plasticity and genetic adaptation to high-altitude hypoxia in vertebrates
-
Storz JF, Scott GR, Cheviron ZA (2010) Phenotypic plasticity and genetic adaptation to high-altitude hypoxia in vertebrates. J Exp Biol 213:2565–2574
-
(2010)
J Exp Biol
, vol.213
, pp. 2565-2574
-
-
Storz, JF1
Scott, GR2
Cheviron, ZA3
-
59
-
-
70149102931
-
Evolutionary and functional insights into the mechanism underlying high-altitude adaptation of deer mouse hemoglobin
-
Storz JF, Runck AM, Sabatino SJ et al (2009) Evolutionary and functional insights into the mechanism underlying high-altitude adaptation of deer mouse hemoglobin. Proc Natl Acad Sci USA 106:14450–14455
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 14450-14455
-
-
Storz, JF1
Runck, AM2
Sabatino, SJ3
-
60
-
-
77954843627
-
Genetic differences in hemoglobin function between highland and lowland deer mice
-
Storz JF, Runck AM, Moriyama H et al (2010) Genetic differences in hemoglobin function between highland and lowland deer mice. J Exp Biol 213:2565–2574
-
(2010)
J Exp Biol
, vol.213
, pp. 2565-2574
-
-
Storz, JF1
Runck, AM2
Moriyama, H3
-
61
-
-
67749098058
-
Stepwise acquisition of pyrimethamine resistance in the malaria parasite
-
Lozovsky E R, Chookajorn T, Brown KM et al (2009) Stepwise acquisition of pyrimethamine resistance in the malaria parasite. Proc Natl Acad Sci USA 106:12025–12030
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 12025-12030
-
-
Lozovsky, E R1
Chookajorn, T2
Brown, KM3
-
62
-
-
0030612598
-
A single amino acid substitution converts a carboxylesterase to an organophosphorus hydrolase and confers insecticide resistance on a blowfly
-
Newcomb RD, Campbell PM, Ollis DL et al (1997) A single amino acid substitution converts a carboxylesterase to an organophosphorus hydrolase and confers insecticide resistance on a blowfly. Proc Natl Acad Sci USA 94: 7464–7468
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 7464-7468
-
-
Newcomb, RD1
Campbell, PM2
Ollis, DL3
-
63
-
-
34047218882
-
The molecular basis of high-altitude adaptation in deer mice
-
Storz JF, Sabatino SJ, Hoffmann FG et al (2007) The molecular basis of high-altitude adaptation in deer mice. PloS Genet 3:e45
-
(2007)
PloS Genet
, vol.3
, pp. e45
-
-
Storz, JF1
Sabatino, SJ2
Hoffmann, FG3
-
64
-
-
56049122929
-
Effects of spatially varying selection on nucleotide diversity and linkage disequilibrium: insights from deer mouse globin genes
-
Storz JF, Kelly JK (2008) Effects of spatially varying selection on nucleotide diversity and linkage disequilibrium: insights from deer mouse globin genes. Genetics 180:367–379
-
(2008)
Genetics
, vol.180
, pp. 367-379
-
-
Storz, JF1
Kelly, JK2
-
65
-
-
1942531303
-
Resurrecting ancient genes: experimental analysis of extinct molecules
-
Thornton JW (2004) Resurrecting ancient genes: experimental analysis of extinct molecules. Nat Rev Genet 5:366–375
-
(2004)
Nat Rev Genet
, vol.5
, pp. 366-375
-
-
Thornton, JW1
-
66
-
-
21044435697
-
Sign epistasis and genetic constraint on evolutionary trajectories
-
Weinreich DM, Watson RA, Chao L (2005) Sign epistasis and genetic constraint on evolutionary trajectories. Evolution 59:1165–1174
-
(2005)
Evolution
, vol.59
, pp. 1165-1174
-
-
Weinreich, DM1
Watson, RA2
Chao, L3
-
67
-
-
33846551980
-
Empirical fitness landscapes reveal accessible evolutionary paths
-
Poelwijk FJ, Kiviet DJ, Weinreich DM et al (2007) Empirical fitness landscapes reveal accessible evolutionary paths. Nature 445:383–386
-
(2007)
Nature
, vol.445
, pp. 383-386
-
-
Poelwijk, FJ1
Kiviet, DJ2
Weinreich, DM3
-
68
-
-
76549129324
-
Adaptive landscapes and protein evolution
-
Carneiro M, Hartl DL (2005) Adaptive landscapes and protein evolution. Proc Natl Acad Sci USA 107:1747–1751
-
(2005)
Proc Natl Acad Sci USA
, vol.107
, pp. 1747-1751
-
-
Carneiro, M1
Hartl, DL2
-
69
-
-
24644504692
-
Compensatory evolution of interacting gene products through multifunctional intermediates
-
Haag ES, Molla MN (2005) Compensatory evolution of interacting gene products through multifunctional intermediates. Evolution 59: 1620–1632
-
(2005)
Evolution
, vol.59
, pp. 1620-1632
-
-
Haag, ES1
Molla, MN2
-
70
-
-
33845672511
-
Compensatory vs. pseudocom-pensatory evolution in molecular and developmental interactions
-
Haag ES (2007) Compensatory vs. pseudocom-pensatory evolution in molecular and developmental interactions. Genetica 129:45–55
-
(2007)
Genetica
, vol.129
, pp. 45-55
-
-
Haag, ES1
-
72
-
-
0345293158
-
Why are some human disease-associated mutations fixed in mice?
-
Gao L, Zhang J (2003) Why are some human disease-associated mutations fixed in mice? Trends Genet 19:678–681
-
(2003)
Trends Genet
, vol.19
, pp. 678-681
-
-
Gao, L1
Zhang, J2
-
73
-
-
9444269272
-
Compensated deleterious mutations in insect genomes
-
Kulathinal RJ, Bettencourt BR, Hartl DL (2004) Compensated deleterious mutations in insect genomes. Science 306:1553–1554
-
(2004)
Science
, vol.306
, pp. 1553-1554
-
-
Kulathinal, RJ1
Bettencourt, BR2
Hartl, DL3
-
74
-
-
21044440015
-
The coupon collector and the suppressor mutation: estimating the number of compensatory mutations by maximum likelihood
-
Poon A, Davis BH, Chao L (2005) The coupon collector and the suppressor mutation: estimating the number of compensatory mutations by maximum likelihood. Genetics 170: 1323–1332
-
(2005)
Genetics
, vol.170
, pp. 1323-1332
-
-
Poon, A1
Davis, BH2
Chao, L3
-
75
-
-
66149185556
-
Compensatory mutations are repeatable and clustered within proteins
-
Davis BH, Poon AFY, Whitlock MC (2009) Compensatory mutations are repeatable and clustered within proteins. Proc Royal Soc B-Biol Sci 276:1823–1827
-
(2009)
Proc Royal Soc B-Biol Sci
, vol.276
, pp. 1823-1827
-
-
Davis, BH1
Poon, AFY2
Whitlock, MC3
-
76
-
-
0036295508
-
Evolution of an antibiotic resistance enzyme constrained by stability and activity trade-offs
-
Wang XJ, Minasov G, Shoichet BK (2002) Evolution of an antibiotic resistance enzyme constrained by stability and activity trade-offs. J Mol Biol 320:85–95
-
(2002)
J Mol Biol
, vol.320
, pp. 85-95
-
-
Wang, XJ1
Minasov, G2
Shoichet, BK3
-
77
-
-
23944490117
-
Missense meanderings in sequence space: a biophysical view of protein evolution
-
DePristo MA, Weinreich DM, Hartl DL (2005) Missense meanderings in sequence space: a biophysical view of protein evolution, Nat Rev Genet 6:678–687
-
(2005)
Nat Rev Genet
, vol.6
, pp. 678-687
-
-
DePristo, MA1
Weinreich, DM2
Hartl, DL3
-
78
-
-
0035793095
-
A secondary drug resistance mutation of TEM-1 beta-lactamase that suppresses misfold-ing and aggregation
-
Sideraki V, Huang WZ, Palzkill T et al (2001) A secondary drug resistance mutation of TEM-1 beta-lactamase that suppresses misfold-ing and aggregation. Proc Natl Acad Sci USA 98:283–288
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 283-288
-
-
Sideraki, V1
Huang, WZ2
Palzkill, T3
-
79
-
-
0000015102
-
Functional biology of adaptation
-
Berry RJ, Crawford TJ, Hewitt GM (eds) Blackwell Scientific Publications, Oxford, UK
-
Feder ME, Watt WB (1992) Functional biology of adaptation. In: Berry RJ, Crawford TJ, Hewitt GM (eds.) Genes in ecology. Blackwell Scientific Publications, Oxford, UK
-
(1992)
Genes in ecology
-
-
Feder, ME1
Watt, WB2
-
80
-
-
71549158571
-
Linking genotypes to phenotypes and fitness: how mechanistic biology can inform molecular ecology
-
Dalziel AC, Rogers SM, Schulte PM (2009) Linking genotypes to phenotypes and fitness: how mechanistic biology can inform molecular ecology. Mol Ecol 18:4997–5017
-
(2009)
Mol Ecol
, vol.18
, pp. 4997-5017
-
-
Dalziel, AC1
Rogers, SM2
Schulte, PM3
-
81
-
-
38949120060
-
Evolutionary transitions in floral color
-
Rausher MD (2008) Evolutionary transitions in floral color. Int J Plant Sci 169:7–21
-
(2008)
Int J Plant Sci
, vol.169
, pp. 7-21
-
-
Rausher, MD1
-
82
-
-
79952044087
-
Population genetics, pleiotropy, and the preferential fixation of mutations during adaptive evolution
-
Streisfeld MA, Rausher MD (2010) Population genetics, pleiotropy, and the preferential fixation of mutations during adaptive evolution. Evolution 65:629–642
-
(2010)
Evolution
, vol.65
, pp. 629-642
-
-
Streisfeld, MA1
Rausher, MD2
-
83
-
-
33845878007
-
Flux control and excess capacity in the enzymes of glycolysis and their relationship to flight metabolism in Drosophila mela- nogaster
-
Eanes WF, Merritt TJS, Flowers JM et al (2006) Flux control and excess capacity in the enzymes of glycolysis and their relationship to flight metabolism in Drosophila mela- nogaster. Proc Natl Acad Sci USA 103:19413–19418
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 19413-19418
-
-
Eanes, WF1
Merritt, TJS2
Flowers, JM3
-
84
-
-
62449196667
-
Direct evidence that genetic variation in glycerol-3-phosphate and malate dehydrogenase genes (Gpdh and Mdh1) affects adult ethanol tolerance in Drosophila melanogaster
-
Eanes WF, Merritt TJS, Flowers JM et al (2009) Direct evidence that genetic variation in glycerol-3-phosphate and malate dehydrogenase genes (Gpdh and Mdh1) affects adult ethanol tolerance in Drosophila melanogaster. Genetics 181:607–614
-
(2009)
Genetics
, vol.181
, pp. 607-614
-
-
Eanes, WF1
Merritt, TJS2
Flowers, JM3
-
85
-
-
34548118363
-
Adaptive evolution of metabolic pathways in Drosophila
-
Flowers JM, Sezgin E, Kumagai S et al (2007) Adaptive evolution of metabolic pathways in Drosophila. Mol Biol Evol 24:1347–1354
-
(2007)
Mol Biol Evol
, vol.24
, pp. 1347-1354
-
-
Flowers, JM1
Sezgin, E2
Kumagai, S3
-
86
-
-
56449112469
-
Evolutionary constraint and adaptation in the metabolic network of Drosophila
-
Greenberg AJ, Stockwell SR, Clark AG (2008) Evolutionary constraint and adaptation in the metabolic network of Drosophila. Mol Biol Evol 25:2537–2546
-
(2008)
Mol Biol Evol
, vol.25
, pp. 2537-2546
-
-
Greenberg, AJ1
Stockwell, SR2
Clark, AG3
-
87
-
-
68949215579
-
Quantifying interactions within the NADP(H) enzyme network in Drosophila melanogaster
-
Merritt TJS., Kuczynski C, Sezgin E et al (2009) Quantifying interactions within the NADP(H) enzyme network in Drosophila melanogaster. Genetics 182:565–574
-
(2009)
Genetics
, vol.182
, pp. 565-574
-
-
Merritt, TJS.1
Kuczynski, C2
Sezgin, E3
-
88
-
-
33644787011
-
Triglyceride pools, flight and activity variation at the Gpdh locus in Drosophila melanogaster
-
Merritt TJS, Sezgin E, Zhu CT et al (2006) Triglyceride pools, flight and activity variation at the Gpdh locus in Drosophila melanogaster. Genetics 172:293–304
-
(2006)
Genetics
, vol.172
, pp. 293-304
-
-
Merritt, TJS1
Sezgin, E2
Zhu, CT3
|