A protein kinase C activity localized to neuropeptide Y-like neurons mediates ethanol intoxication in Drosophila melanogaster

Neuroscience

Volumn 156, Issue 1, 2008, Pages 42-47

  Chen, J ^a   Zhang, Y ^a   Shen, P ^a  

^a UNIVERSITY OF GEORGIA   (United States)

Author keywords

ethanol resistance; ethanol tolerance; neuropeptide F; PKA; PKC

Indexed keywords

ISOENZYME; NEUROPEPTIDE; NEUROPEPTIDE F; NEUROPEPTIDE Y; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; UNCLASSIFIED DRUG;

ALCOHOL INTOXICATION; ALCOHOL METABOLISM; ALCOHOL TOLERANCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; ENZYME ACTIVITY; ENZYME LOCALIZATION; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; RNA INTERFERENCE;

ALCOHOL-INDUCED DISORDERS, NERVOUS SYSTEM; ANIMALS; AXONS; BRAIN; CALCIUM SIGNALING; CENTRAL NERVOUS SYSTEM DEPRESSANTS; DENDRITES; DISEASE MODELS, ANIMAL; DROSOPHILA MELANOGASTER; DRUG RESISTANCE; ENZYME ACTIVATION; ETHANOL; FEMALE; ISOENZYMES; NEURONS; NEUROPEPTIDE Y; NEUROPEPTIDES; PROTEIN KINASE C; RNA INTERFERENCE; TIME FACTORS;

EID: 51249095590     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2008.07.008     Document Type: Article

References (33)

1. Bannon A.W., Seda J., Carmouche M., Francis J.M., Norman M.H., Karbon B., and McCaleb M.L. Behavioral characterization of neuropeptide Y knockout mice. Brain Res 868 (2000) 79-87
2. Bausenwein B., Muller N.R., and Heisenberg M. Behavior-dependent activity labeling in the central complex of Drosophila during controlled visual stimulation. J Comp Neurol 340 (1994) 255-268
3. Berger K.H., Heberlein U., and Moore M.S. Rapid and chronic: two distinct forms of ethanol tolerance in Drosophila. Alcohol Clin Exp Res 28 (2004) 1469-1480
4. Brain S.D., and Cox H.M. Neuropeptides and their receptors: innovative science providing novel therapeutic targets. Br J Pharmacol 147 Suppl 1 (2006) S202-S211
5. Broughton S.J., Kane N.S., Arthur B., Yoder M., Greenspan R.J., and Robichon A. Endogenously inhibited protein kinase C in transgenic Drosophila embryonic neuroblasts down regulates the outgrowth of type I and II processes of cultured mature neurons. J Cell Biochem 60 (1996) 584-599
6. Brown M.R., Crim J.W., Arata R.C., Cai H.N., Chun C., and Shen P. Identification of a Drosophila brain-gut peptide related to the neuropeptide Y family. Peptides 20 (1999) 1035-1042
7. Corl A.B., Rodan A.R., and Heberlein U. Insulin signaling in the nervous system regulates ethanol intoxication in Drosophila melanogaster. Nat Neurosci 8 (2005) 18-19
8. Dietzl G., Chen D., Schnorrer F., Su K.C., Barinova Y., Fellner M., Gasser B., Kinsey K., Oppel S., Scheiblauer S., Couto A., Marra V., Keleman K., and Dickson B.J. A genome-wide transgenic RNAi library for conditional gene inactivation in Drosophila. Nature 448 (2007) 151-156
9. Erickson J.C., Clegg K.E., and Palmiter R.D. Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y. Nature 381 (1996) 415-421
10. Erickson J.C., Hollopeter G., and Palmiter R.D. Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y. Science 274 (1996) 1704-1707
11. Ghezzi A., Al-Hasan Y.M., Larios L.E., Bohm R.A., and Atkinson N.S. slo K(+) channel gene regulation mediates rapid drug tolerance. Proc Natl Acad Sci U S A 101 (2004) 17276-17281
12. Gordon A.S., Yao L., Wu Z.L., Coe I.R., and Diamond I. Ethanol alters the subcellular localization of delta- and epsilon protein kinase C in NG108-15 cells. Mol Pharmacol 52 (1997) 554-559
13. Hammond S.M., Bernstein E., Beach D., and Hannon G.J. An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature 404 (2000) 293-296
14. Hodge C.W., Mehmert K.K., Kelley S.P., McMahon T., Haywood A., Olive M.F., Wang D., Sanchez-Perez A.M., and Messing R.O. Supersensitivity to allosteric GABA(A) receptor modulators and alcohol in mice lacking PKCepsilon. Nat Neurosci 2 (1999) 997-1002
15. Jones S.M., Howell K.E., Henley J.R., Cao H., and McNiven M.A. Role of dynamin in the formation of transport vesicles from the trans-Golgi network. Science 279 (1998) 573-577
16. Michel M.C., Beck-Sickinger A., Cox H., Doods H.N., Herzog H., Larhammar D., Quirion R., Schwartz T., and Westfall T. XVI. International Union of Pharmacology recommendations for the nomenclature of neuropeptide Y, peptide YY, and pancreatic polypeptide receptors. Pharmacol Rev 50 (1998) 143-150
17. Moore M.S., DeZazzo J., Luk A.Y., Tully T., Singh C.M., and Heberlein U. Ethanol intoxication in Drosophila: Genetic and pharmacological evidence for regulation by the cAMP signaling pathway. Cell 93 (1998) 997-1007
18. Newton P.M., and Ron D. Protein kinase C and alcohol addiction. Pharmacol Res 55 (2007) 570-577
19. Rajpara S.M., Garcia P.D., Roberts R., Eliassen J.C., Owens D.F., Maltby D., Myers R.M., and Mayeri E. Identification and molecular cloning of a neuropeptide Y homolog that produces prolonged inhibition in Aplysia neurons. Neuron 9 (1992) 505-513
20. Robinson P.J., Sontag J.M., Liu J.P., Fykse E.M., Slaughter C., McMahon H., and Sudhof T.C. Dynamin GTPase regulated by protein kinase C phosphorylation in nerve terminals. Nature 365 (1993) 163-166
21. Rodan A.R., Kiger Jr. J.A., and Heberlein U. Functional dissection of neuroanatomical loci regulating ethanol sensitivity in Drosophila. J Neurosci 22 (2002) 9490-9501
22. Scholz H., Ramond J., Singh C.M., and Heberlein U. Functional ethanol tolerance in Drosophila. Neuron 28 (2000) 261-271
23. Shieh B.H., Parker L., and Popescu D. Protein kinase C (PKC) isoforms in Drosophila. J Biochem 132 (2002) 523-527
24. Sieburth D., Madison J.M., and Kaplan J.M. PKC-1 regulates secretion of neuropeptides. Nat Neurosci 10 (2007) 49-57
25. Singh C.M., and Heberlein U. Genetic control of acute ethanol-induced behaviors in Drosophila. Alcohol Clin Exp Res 24 (2000) 1127-1136
26. Strauss R., and Heisenberg M. A higher control center of locomotor behavior in the Drosophila brain. J Neurosci 13 (1993) 1852-1861
27. Thiele T.E., Koh M.T., and Pedrazzini T. Voluntary alcohol consumption is controlled via the neuropeptide Y Y1 receptor. J Neurosci 22 (2002) RC208
28. Thiele T.E., Marsh D.J., Ste Marie L., Bernstein I.L., and Palmiter R.D. Ethanol consumption and resistance are inversely related to neuropeptide Y levels. Nature 396 (1998) 366-369
29. Thorsell A., Michalkiewicz M., Dumont Y., Quirion R., Caberlotto L., Rimondini R., Mathe A.A., and Heilig M. Behavioral insensitivity to restraint stress, absent fear suppression of behavior and impaired spatial learning in transgenic rats with hippocampal neuropeptide Y overexpression. Proc Natl Acad Sci U S A 97 (2000) 12852-12857
30. Vosshall L.B., Wong A.M., and Axel R. An olfactory sensory map in the fly brain. Cell 102 (2000) 147-159
31. Wang J., Ma X., Yang J.S., Zheng X., Zugates C.T., Lee C.H., and Lee T. Transmembrane/juxtamembrane domain-dependent Dscam distribution and function during mushroom body neuronal morphogenesis. Neuron 43 (2004) 663-672
32. Wen T., Parrish C.A., Xu D., Wu Q., and Shen P. Drosophila neuropeptide F and its receptor, NPFR1, define a signaling pathway that acutely modulates alcohol sensitivity. Proc Natl Acad Sci U S A 102 (2005) 2141-2146
33. Yang Z., Li H., Chai Z., Fullerton M.J., Cao Y., Toh B.H., Funder J.W., and Liu J.P. Dynamin II regulates hormone secretion in neuroendocrine cells. J Biol Chem 276 (2001) 4251-4260