Loperamide, an antidiarrhea drug, has antitumor activity by inducing cell apoptosis

Pharmacological Research

Volumn 65, Issue 3, 2012, Pages 372-378

  Gong, Xing Wen ^a   Xu, Yu Hong ^b   Chen, Xiao Ling ^b   Wang, Yong Xiang ^b  

^a ZHEJIANG GONGSHANG UNIVERSITY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

Antitumor activity; Caspase 3 activation; Cell apoptosis; Cytotoxicity; Loperamide

Indexed keywords

CASPASE 3; LIPOCORTIN 5; LOPERAMIDE; PROPIDIUM IODIDE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CELL CYCLE ARREST; CELL PROLIFERATION; CELL STRUCTURE; CONTROLLED STUDY; CYTOTOXICITY; DIPLOIDY; DRUG DETERMINATION; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME INHIBITION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IC 50; KIDNEY CARCINOMA; LIVER CANCER; LUNG CANCER; OSTEOSARCOMA; OSTEOSARCOMA CELL; OVARY CANCER; PRIORITY JOURNAL; STOMACH CANCER; TREATMENT DURATION; TREATMENT RESPONSE; TUMOR CELL;

ANTIDIARRHEALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CYTOTOXINS; HUMANS; LOPERAMIDE; NEOPLASMS;

EID: 84857059729     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2011.11.007     Document Type: Article

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