메뉴 건너뛰기




Volumn 5, Issue 6, 2012, Pages 304-317

Loss of R-spondin1 and Foxl2 amplifies female-to-male sex reversal in XX mice

Author keywords

Foxl2; Mouse; Ovarian differentiation; R spondin1; XX sex reversal

Indexed keywords

MUS; VERTEBRATA;

EID: 84857046244     PISSN: 16615425     EISSN: 16615433     Source Type: Journal    
DOI: 10.1159/000334517     Document Type: Article
Times cited : (53)

References (85)
  • 1
    • 43249092522 scopus 로고    scopus 로고
    • Molecular cloning and quantitative expression of sexually dimorphic markers Dmrt1 and Foxl2 during female-tomale sex change in epinephelus merra
    • Alam MA, Kobayashi Y, Horiguchi R, Hirai T, Nakamura M: Molecular cloning and quantitative expression of sexually dimorphic markers Dmrt1 and Foxl2 during female-tomale sex change in epinephelus merra. Gen Comp Endocrinol 157: 75-85 (2008).
    • (2008) Gen Comp Endocrinol , vol.157 , pp. 75-85
    • Alam, M.A.1    Kobayashi, Y.2    Horiguchi, R.3    Hirai, T.4    Nakamura, M.5
  • 2
    • 78149499656 scopus 로고    scopus 로고
    • Sexually dimorphic gene expression in the gonad and liver of shovelnose sturgeon (Scaphirhynchus platorynchus)
    • Amberg JJ, Goforth R, Stefanavage T, Sepúlveda MS: Sexually dimorphic gene expression in the gonad and liver of shovelnose sturgeon (Scaphirhynchus platorynchus). Fish Physiol Biochem 36: 923-932 (2010).
    • (2010) Fish Physiol Biochem , vol.36 , pp. 923-932
    • Amberg, J.J.1    Goforth, R.2    Stefanavage, T.3    Sepúlveda, M.S.4
  • 4
    • 11244338157 scopus 로고    scopus 로고
    • An evolutionary and functional analysis of Foxl2 in rainbow trout gonad differentiation
    • Baron D, Cocquet J, Xia XH, Fellous M, Guiguen Y, Veitia RA: An evolutionary and functional analysis of Foxl2 in rainbow trout gonad differentiation. J Mol Endocrinol 33: 705-715 (2004).
    • (2004) J Mol Endocrinol , vol.33 , pp. 705-715
    • Baron, D.1    Cocquet, J.2    Xia, X.H.3    Fellous, M.4    Guiguen, Y.5    Veitia, R.A.6
  • 5
    • 30344475256 scopus 로고    scopus 로고
    • Homozygous inactivation of Sox9 causes complete XY sex reversal in mice
    • Barrionuevo F, Bagheri-Fam S, Klattig J, Kist R, Taketo MM, et al: Homozygous inactivation of Sox9 causes complete XY sex reversal in mice. Biol Reprod 74: 195-201 (2006).
    • (2006) Biol Reprod , vol.74 , pp. 195-201
    • Barrionuevo, F.1    Bagheri-Fam, S.2    Klattig, J.3    Kist, R.4    Taketo, M.M.5
  • 6
  • 7
    • 44449101091 scopus 로고    scopus 로고
    • Sdmg1 is a conserved transmembrane protein associated with germ cell sex determination and germline-soma interactions in mice
    • Best D, Sahlender DA, Walther N, Peden AA, Adams IR: Sdmg1 is a conserved transmembrane protein associated with germ cell sex determination and germline-soma interactions in mice. Development 135: 1415-1425 (2008).
    • (2008) Development , vol.135 , pp. 1415-1425
    • Best, D.1    Sahlender, D.A.2    Walther, N.3    Peden, A.A.4    Adams, I.R.5
  • 8
    • 33646481775 scopus 로고    scopus 로고
    • Sex steroid concentrations and localization of steroidogenic enzyme expression in free-ranging female northern fur seals (Callorhinus ursinus)
    • Browne P, Conley AJ, Spraker T, Ream RR, Lasley BL: Sex steroid concentrations and localization of steroidogenic enzyme expression in free-ranging female northern fur seals (Callorhinus ursinus). Gen Comp Endocrinol 147: 175-183 (2006).
    • (2006) Gen Comp Endocrinol , vol.147 , pp. 175-183
    • Browne, P.1    Conley, A.J.2    Spraker, T.3    Ream, R.R.4    Lasley, B.L.5
  • 9
    • 0035023631 scopus 로고    scopus 로고
    • Spatially dynamic expression of Sry in mouse genital ridges
    • Bullejos M, Koopman P: Spatially dynamic expression of Sry in mouse genital ridges. Dev Dyn 221: 201-205 (2001).
    • (2001) Dev Dyn , vol.221 , pp. 201-205
    • Bullejos, M.1    Koopman, P.2
  • 10
    • 0033628159 scopus 로고    scopus 로고
    • SRY - Negative, XX intersex horses: The need for pedigree studies to examine the mode of inheritance of the condition
    • Buoen LC, Zhang TQ, Weber AF, Ruth GR: SRY - negative, XX intersex horses: the need for pedigree studies to examine the mode of inheritance of the condition. Equine Vet J 32: 78-81 (2000).
    • (2000) Equine Vet J , vol.32 , pp. 78-81
    • Buoen, L.C.1    Zhang, T.Q.2    Weber, A.F.3    Ruth, G.R.4
  • 12
    • 42449095964 scopus 로고    scopus 로고
    • Activation of beta-catenin signaling by Rspo1 controls differentiation of the mammalian ovary
    • Chassot AA, Ranc F, Gregoire EP, Roepers-Gajadien HL, Taketo MM, et al: Activation of beta-catenin signaling by Rspo1 controls differentiation of the mammalian ovary. Hum Mol Genet 17: 1264-1277 (2008a).
    • (2008) Hum Mol Genet , vol.17 , pp. 1264-1277
    • Chassot, A.A.1    Ranc, F.2    Gregoire, E.P.3    Roepers-Gajadien, H.L.4    Taketo, M.M.5
  • 14
    • 80053451837 scopus 로고    scopus 로고
    • RSPO1/ β -catenin signaling pathway regulates oogonia differentiation and entry into meiosis in the mouse fetal ovary
    • Chassot AA, Gregoire EP, Lavery R, Taketo MM, de Rooij DG, et al: RSPO1/ β -catenin signaling pathway regulates oogonia differentiation and entry into meiosis in the mouse fetal ovary. PLoS One 6:e25641 (2011).
    • (2011) PLoS One , vol.6
    • Chassot, A.A.1    Gregoire, E.P.2    Lavery, R.3    Taketo, M.M.4    De Rooij, D.G.5
  • 15
    • 58549112365 scopus 로고    scopus 로고
    • Endothelial cell migration directs testis cord formation
    • Combes AN, Wilhelm D, Davidson T, Dejana E, Harley V, et al: Endothelial cell migration directs testis cord formation. Dev Biol 326: 112-120 (2009).
    • (2009) Dev Biol , vol.326 , pp. 112-120
    • Combes, A.N.1    Wilhelm, D.2    Davidson, T.3    Dejana, E.4    Harley, V.5
  • 16
    • 51349121523 scopus 로고    scopus 로고
    • Peritubular myoid cells are not the migrating population required for testis cord formation in the XY gonad
    • Cool J, Carmona FD, Szucsik JC, Capel B: Peritubular myoid cells are not the migrating population required for testis cord formation in the XY gonad. Sex Dev 2: 128-133 (2008).
    • (2008) Sex Dev , vol.2 , pp. 128-133
    • Cool, J.1    Carmona, F.D.2    Szucsik, J.C.3    Capel, B.4
  • 17
    • 0342445418 scopus 로고    scopus 로고
    • Postnatal sex reversal of the ovaries in mice lacking estrogen receptors alpha and beta
    • Couse JF, Hewitt SC, Bunch DO, Sar M, Walker VR, et al: Postnatal sex reversal of the ovaries in mice lacking estrogen receptors alpha and beta. Science 286: 2328-2331 (1999).
    • (1999) Science , vol.286 , pp. 2328-2331
    • Couse, J.F.1    Hewitt, S.C.2    Bunch, D.O.3    Sar, M.4    Walker, V.R.5
  • 18
    • 0035131812 scopus 로고    scopus 로고
    • The putative forkhead transcription factor FOXL2 is mutated in blepharophimosis/ ptosis/epicanthus inversus syndrome
    • Crisponi L, Deiana M, Loi A, Chiappe F, Uda M, et al: The putative forkhead transcription factor FOXL2 is mutated in blepharophimosis/ ptosis/epicanthus inversus syndrome. Nat Genet 27: 159-166 (2001).
    • (2001) Nat Genet , vol.27 , pp. 159-166
    • Crisponi, L.1    Deiana, M.2    Loi, A.3    Chiappe, F.4    Uda, M.5
  • 19
    • 0037318857 scopus 로고    scopus 로고
    • FOXL2 and BPES : Mutational hotspots, phenotypic variability, and revision of the genotype-phenotype correlation
    • De Baere E, Beysen D, Oley C, Lorenz B, Cocquet J, et al: FOXL2 and BPES : mutational hotspots, phenotypic variability, and revision of the genotype-phenotype correlation. Am J Hum Genet 72: 478-487 (2003).
    • (2003) Am J Hum Genet , vol.72 , pp. 478-487
    • De Baere, E.1    Beysen, D.2    Oley, C.3    Lorenz, B.4    Cocquet, J.5
  • 20
    • 11144352827 scopus 로고    scopus 로고
    • Isolation of chicken homolog of the Foxl2 gene and comparison of its expression patterns with those of aromatase during ovarian development
    • Govoroun MS, Pannetier M, Pailhoux E, Cocquet J, Brillard JP, et al: Isolation of chicken homolog of the Foxl2 gene and comparison of its expression patterns with those of aromatase during ovarian development. Dev Dyn 231: 859-870 (2004).
    • (2004) Dev Dyn , vol.231 , pp. 859-870
    • Govoroun, M.S.1    Pannetier, M.2    Pailhoux, E.3    Cocquet, J.4    Brillard, J.P.5
  • 22
    • 0033230616 scopus 로고    scopus 로고
    • Intestinal polyposis in mice with a dominant stable mutation of the betacatenin gene
    • Harada N, Tamai Y, Ishikawa T, Sauer B, Takaku K, et al: Intestinal polyposis in mice with a dominant stable mutation of the betacatenin gene. EMBO J 18: 5931-5942 (1999).
    • (1999) EMBO J , vol.18 , pp. 5931-5942
    • Harada, N.1    Tamai, Y.2    Ishikawa, T.3    Sauer, B.4    Takaku, K.5
  • 23
    • 23844544781 scopus 로고    scopus 로고
    • The partial female to male sex reversal in Wnt-4 -deficient females involves induced expression of testosterone biosynthetic genes and testosterone production, and depends on androgen action
    • Heikkilä M, Prunskaite R, Naillat F, Itäranta P, Vuoristo J, et al: The partial female to male sex reversal in Wnt-4 -deficient females involves induced expression of testosterone biosynthetic genes and testosterone production, and depends on androgen action. Endocrinology 146: 4016-4023 (2005).
    • (2005) Endocrinology , vol.146 , pp. 4016-4023
    • Heikkilä, M.1    Prunskaite, R.2    Naillat, F.3    Itäranta, P.4    Vuoristo, J.5
  • 24
    • 73649109576 scopus 로고    scopus 로고
    • FGF signaling directs a center-to-pole expansion of tubulogenesis in mouse testis differentiation
    • Hiramatsu R, Harikae K, Tsunekawa N, Kurohmaru M, Matsuo I, et al: FGF signaling directs a center-to-pole expansion of tubulogenesis in mouse testis differentiation. Development 137: 303-312 (2010).
    • (2010) Development , vol.137 , pp. 303-312
    • Hiramatsu, R.1    Harikae, K.2    Tsunekawa, N.3    Kurohmaru, M.4    Matsuo, I.5
  • 26
    • 38549092514 scopus 로고    scopus 로고
    • Sexual dimorphic expression of genes in gonads during early differentiation of a teleost fish, the Nile tilapia Oreochromis niloticus
    • Ijiri S, Kaneko H, Kobayashi T, Wang DS, Sakai F, et al: Sexual dimorphic expression of genes in gonads during early differentiation of a teleost fish, the Nile tilapia Oreochromis niloticus. Biol Reprod 78: 333-341 (2008).
    • (2008) Biol Reprod , vol.78 , pp. 333-341
    • Ijiri, S.1    Kaneko, H.2    Kobayashi, T.3    Wang, D.S.4    Sakai, F.5
  • 27
    • 0025258480 scopus 로고
    • A human XY female with a frame shift mutation in the candidate testis-determining gene SRY
    • Jäger RJ, Anvret M, Hall K, Scherer G: A human XY female with a frame shift mutation in the candidate testis-determining gene SRY. Nature 348: 452-454 (1990).
    • (1990) Nature , vol.348 , pp. 452-454
    • Jäger, R.J.1    Anvret, M.2    Hall, K.3    Scherer, G.4
  • 28
    • 23844455584 scopus 로고    scopus 로고
    • Mitogenic influence of human Rspondin1 on the intestinal epithelium
    • Kim KA, Kakitani M, Zhao JS, Oshima T, Tang T, et al: Mitogenic influence of human Rspondin1 on the intestinal epithelium. Science 309: 1256-1259 (2005).
    • (2005) Science , vol.309 , pp. 1256-1259
    • Kim, K.A.1    Kakitani, M.2    Zhao, J.S.3    Oshima, T.4    Tang, T.5
  • 29
    • 33645318206 scopus 로고    scopus 로고
    • R-Spondin proteins: A novel link to beta-catenin activation
    • Kim KA, Zhao J, Andarmani S, Kakitani M, Oshima T, et al: R-Spondin proteins: a novel link to beta-catenin activation. Cell Cycle 5: 23-26 (2006a).
    • (2006) Cell Cycle , vol.5 , pp. 23-26
    • Kim, K.A.1    Zhao, J.2    Andarmani, S.3    Kakitani, M.4    Oshima, T.5
  • 30
    • 33746907822 scopus 로고    scopus 로고
    • Fgf9 and Wnt4 act as antagonistic signals to regulate mammalian sex determination
    • Kim Y, Kobayashi A, Sekido R, DiNapoli L, Brennan J, et al: Fgf9 and Wnt4 act as antagonistic signals to regulate mammalian sex determination. PLoS Biol 4:e187 (2006b).
    • (2006) PLoS Biol , vol.4
    • Kim, Y.1    Kobayashi, A.2    Sekido, R.3    Dinapoli, L.4    Brennan, J.5
  • 31
    • 42549143717 scopus 로고    scopus 로고
    • R-spondin1 and Foxl2 act into two distinct cellular types during goat ovarian differentiation
    • Kocer A, Pinheiro I, Pannetier M, Renault L, Parma P, et al: R-spondin1 and Foxl2 act into two distinct cellular types during goat ovarian differentiation. BMC Dev Biol 8: 36 (2008).
    • (2008) BMC Dev Biol , vol.8 , pp. 36
    • Kocer, A.1    Pinheiro, I.2    Pannetier, M.3    Renault, L.4    Parma, P.5
  • 32
    • 0025243412 scopus 로고
    • Expression of a candidate sex-determining gene during mouse testis differentiation
    • Koopman P, Münsterberg A, Capel B, Vivian N, Lovell-Badge R: Expression of a candidate sex-determining gene during mouse testis differentiation. Nature 348: 450-452 (1990).
    • (1990) Nature , vol.348 , pp. 450-452
    • Koopman, P.1    Münsterberg, A.2    Capel, B.3    Vivian, N.4    Lovell-Badge, R.5
  • 33
    • 70349783734 scopus 로고    scopus 로고
    • Sumoylation of forkhead l2 by Ubc9 is required for its activity as a transcriptional repressor of the steroidogenic acute regulatory gene
    • Kuo FT, Bentsi-Barnes IK, Barlow GM, Bae J, Pisarska MD: Sumoylation of forkhead l2 by Ubc9 is required for its activity as a transcriptional repressor of the steroidogenic acute regulatory gene. Cell Signal 21: 1935-1944 (2009).
    • (2009) Cell Signal , vol.21 , pp. 1935-1944
    • Kuo, F.T.1    Bentsi-Barnes, I.K.2    Barlow, G.M.3    Bae, J.4    Pisarska, M.D.5
  • 34
    • 34547470459 scopus 로고    scopus 로고
    • Molecular cloning of doublesex and mab-3-related transcription factor 1, forkhead transcription factor gene 2, and two types of cytochrome p450 aromatase in southern catfish and their possible roles in sex differentiation
    • Liu ZH, Wul FR, Jiao BW, Zhang XY, Hu CJ, et al: Molecular cloning of doublesex and mab-3-related transcription factor 1, forkhead transcription factor gene 2, and two types of cytochrome p450 aromatase in southern catfish and their possible roles in sex differentiation. J Endocrinol 194: 223-241 (2007).
    • (2007) J Endocrinol , vol.194 , pp. 223-241
    • Liu, Z.H.1    Wul, F.R.2    Jiao, B.W.3    Zhang, X.Y.4    Hu, C.J.5
  • 35
    • 0038649161 scopus 로고    scopus 로고
    • Etiology of ovarian failure in blepharophimosis ptosis epicanthus inversus syndrome: FOXL2 is a conserved, early-acting gene in vertebrate ovarian development
    • Loffler KA, Zarkower D, Koopman P: Etiology of ovarian failure in blepharophimosis ptosis epicanthus inversus syndrome: FOXL2 is a conserved, early-acting gene in vertebrate ovarian development. Endocrinology 144: 3237-3243 (2003).
    • (2003) Endocrinology , vol.144 , pp. 3237-3243
    • Loffler, K.A.1    Zarkower, D.2    Koopman, P.3
  • 36
    • 0036149985 scopus 로고    scopus 로고
    • Negative feedback loop of Wnt signaling through upregulation of conductin/ axin2 in colorectal and liver tumors
    • Lustig B, Jerchow B, Sachs M, Weiler S, Pietsch T, et al: Negative feedback loop of Wnt signaling through upregulation of conductin/ axin2 in colorectal and liver tumors. Mol Cell Biol 22: 1184-1193 (2002).
    • (2002) Mol Cell Biol , vol.22 , pp. 1184-1193
    • Lustig, B.1    Jerchow, B.2    Sachs, M.3    Weiler, S.4    Pietsch, T.5
  • 38
    • 0017641110 scopus 로고
    • Very early and transient 17 β -estradiol secretion by fetal sheep ovary. in vitro study
    • Mauléon P, Bézard J, Terqui M: Very early and transient 17 β -estradiol secretion by fetal sheep ovary. In vitro study. Ann Biol Anim Bioch Biophys 17: 399-401 (1977).
    • (1977) Ann Biol Anim Bioch Biophys , vol.17 , pp. 399-401
    • Mauléon, P.1    Bézard, J.2    Terqui, M.3
  • 39
    • 0027466437 scopus 로고
    • A regulatory cascade hypothesis for mammalian sex determination: SRY represses a negative regulator of male development
    • McElreavey K, Vilain E, Abbas N, Herskowitz I, Fellous M: A regulatory cascade hypothesis for mammalian sex determination: SRY represses a negative regulator of male development. Proc Natl Acad Sci USA 90: 3368-3372 (1993).
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 3368-3372
    • McElreavey, K.1    Vilain, E.2    Abbas, N.3    Herskowitz, I.4    Fellous, M.5
  • 41
    • 69249117552 scopus 로고    scopus 로고
    • The PGD2 pathway, independently of FGF9, amplifies SOX9 activity in sertoli cells during male sexual differentiation
    • Moniot B, Declosmenil F, Barrionuevo F, Scherer G, Aritake K, et al: The PGD2 pathway, independently of FGF9, amplifies SOX9 activity in sertoli cells during male sexual differentiation. Development 136: 1813-1821 (2009).
    • (2009) Development , vol.136 , pp. 1813-1821
    • Moniot, B.1    Declosmenil, F.2    Barrionuevo, F.3    Scherer, G.4    Aritake, K.5
  • 42
    • 0032428032 scopus 로고    scopus 로고
    • YAC transgenic analysis reveals Wilms' tumour 1 gene activity in the proliferating coelomic epithelium, developing diaphragm and limb
    • Moore AW, Schedl A, McInnes L, Doyle M, Hecksher-Sorensen J, et al: YAC transgenic analysis reveals Wilms' tumour 1 gene activity in the proliferating coelomic epithelium, developing diaphragm and limb. Mech Dev 79: 169-184 (1998).
    • (1998) Mech Dev , vol.79 , pp. 169-184
    • Moore, A.W.1    Schedl, A.2    McInnes, L.3    Doyle, M.4    Hecksher-Sorensen, J.5
  • 43
    • 77949873863 scopus 로고    scopus 로고
    • Gonadal mRna expression levels of Tgf beta superfamily signaling factors correspond with post-hatching morphological development in American alligators
    • Moore BC, Hamlin HJ, Botteri NL, Guillette LJ: Gonadal mRna expression levels of Tgf beta superfamily signaling factors correspond with post-hatching morphological development in American alligators. Sex Dev 4: 62-72 (2010).
    • (2010) Sex Dev , vol.4 , pp. 62-72
    • Moore, B.C.1    Hamlin, H.J.2    Botteri, N.L.3    Guillette, L.J.4
  • 44
    • 0029742909 scopus 로고    scopus 로고
    • Sox9 expression during gonadal development implies a conserved role for the gene in testis differentiation in mammals and birds
    • Morais da Silva SM, Hacker A, Harley V, Goodfellow P, Swain A, Lovell-Badge R: Sox9 expression during gonadal development implies a conserved role for the gene in testis differentiation in mammals and birds. Nat Genet 14: 62-68 (1996).
    • (1996) Nat Genet , vol.14 , pp. 62-68
    • Morais Da Silva, S.M.1    Hacker, A.2    Harley, V.3    Goodfellow, P.4    Swain, A.5    Lovell-Badge, R.6
  • 45
    • 77952317137 scopus 로고    scopus 로고
    • Wnt4/5a signalling coordinates cell adhesion and entry into meiosis during presumptive ovarian follicle development
    • Naillat F, Prunskaite-Hyyryläinen R, Pietilä I, Sormunen R, Jokela T, et al: Wnt4/5a signalling coordinates cell adhesion and entry into meiosis during presumptive ovarian follicle development. Hum Mol Genet 19: 1539-1550 (2010).
    • (2010) Hum Mol Genet , vol.19 , pp. 1539-1550
    • Naillat, F.1    Prunskaite-Hyyryläinen, R.2    Pietilä, I.3    Sormunen, R.4    Jokela, T.5
  • 46
    • 67650069260 scopus 로고    scopus 로고
    • Molecular cloning and gene expression of Cg-Foxl2 during the development and the adult gametogenetic cycle in the oyster Crassostrea gigas
    • Naimi A, Martinez AS, Specq ML, Diss B, Mathieu M, Sourdaine P: Molecular cloning and gene expression of Cg-Foxl2 during the development and the adult gametogenetic cycle in the oyster Crassostrea gigas. Comp Biochem Physiol B Biochem Mol Biol 154: 134-142 (2009).
    • (2009) Comp Biochem Physiol B Biochem Mol Biol , vol.154 , pp. 134-142
    • Naimi, A.1    Martinez, A.S.2    Specq, M.L.3    Diss, B.4    Mathieu, M.5    Sourdaine, P.6
  • 47
    • 33646052575 scopus 로고    scopus 로고
    • Molecular cloning and analysis of gonadal expression of foxl2 in the medaka, Oryzias latipes
    • Nakamoto M, Matsuda M, Wang DS, Nagahama Y, Shibata N: Molecular cloning and analysis of gonadal expression of foxl2 in the medaka, Oryzias latipes. Biochem Biophys Res Commun 344: 353-361 (2006).
    • (2006) Biochem Biophys Res Commun , vol.344 , pp. 353-361
    • Nakamoto, M.1    Matsuda, M.2    Wang, D.S.3    Nagahama, Y.4    Shibata, N.5
  • 48
    • 66149086588 scopus 로고    scopus 로고
    • Gonadal sex differentiation and expression of sox9a2, dmrt1, and foxl2 in Oryzias luzonensis
    • Nakamoto M, Muramatsu S, Yoshida S, Matsuda M, Nagahama Y, Shibata N: Gonadal sex differentiation and expression of sox9a2, dmrt1, and foxl2 in Oryzias luzonensis. Genesis 47: 289-299 (2009).
    • (2009) Genesis , vol.47 , pp. 289-299
    • Nakamoto, M.1    Muramatsu, S.2    Yoshida, S.3    Matsuda, M.4    Nagahama, Y.5    Shibata, N.6
  • 49
    • 33744964431 scopus 로고    scopus 로고
    • Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression
    • Nam JS, Turcotte TJ, Smith PF, Choi S, Yoon JK: Mouse cristin/R-spondin family proteins are novel ligands for the Frizzled 8 and LRP6 receptors and activate beta-catenin-dependent gene expression. J Biol Chem 281: 13247-13257 (2006).
    • (2006) J Biol Chem , vol.281 , pp. 13247-13257
    • Nam, J.S.1    Turcotte, T.J.2    Smith, P.F.3    Choi, S.4    Yoon, J.K.5
  • 50
    • 64149102282 scopus 로고    scopus 로고
    • Xenopus W-linked DM-W induces Foxl2 and Cyp19 expression during ovary formation
    • Okada E, Yoshimoto S, Ikeda N, Kanda H, Tamura K, et al: Xenopus W-linked DM-W induces Foxl2 and Cyp19 expression during ovary formation. Sex Dev 3: 38-42 (2009).
    • (2009) Sex Dev , vol.3 , pp. 38-42
    • Okada, E.1    Yoshimoto, S.2    Ikeda, N.3    Kanda, H.4    Tamura, K.5
  • 53
    • 35748965278 scopus 로고    scopus 로고
    • Loss of Wnt4 and Foxl2 leads to female-to-male sex reversal extending to germ cells
    • Ottolenghi C, Pelosi E, Tran J, Colombino M, Douglass E, et al: Loss of Wnt4 and Foxl2 leads to female-to-male sex reversal extending to germ cells. Hum Mol Genet 16: 2795-2804 (2007).
    • (2007) Hum Mol Genet , vol.16 , pp. 2795-2804
    • Ottolenghi, C.1    Pelosi, E.2    Tran, J.3    Colombino, M.4    Douglass, E.5
  • 54
    • 0028519145 scopus 로고
    • Genetic-analysis of 38XX males with genital ambiguities and true hermaphrodites in pigs
    • Pailhoux E, Popescu PC, Parma P, Boscher J, Legault C, et al: Genetic-analysis of 38XX males with genital ambiguities and true hermaphrodites in pigs. Anim Genet 25: 299-305 (1994).
    • (1994) Anim Genet , vol.25 , pp. 299-305
    • Pailhoux, E.1    Popescu, P.C.2    Parma, P.3    Boscher, J.4    Legault, C.5
  • 55
    • 0035733723 scopus 로고    scopus 로고
    • A 11.7-kb deletion triggers intersexuality and polledness in goats
    • Pailhoux E, Vigier B, Chaffaux S, Servel N, Taourit S, et al: A 11.7-kb deletion triggers intersexuality and polledness in goats. Nat Genet 29: 453-458 (2001).
    • (2001) Nat Genet , vol.29 , pp. 453-458
    • Pailhoux, E.1    Vigier, B.2    Chaffaux, S.3    Servel, N.4    Taourit, S.5
  • 56
    • 0036234843 scopus 로고    scopus 로고
    • Ontogenesis of female-to-male sex-reversal in XX polled goats
    • Pailhoux E, Vigier B, Vaiman D, Servel N, Chaffaux S, et al: Ontogenesis of female-to-male sex-reversal in XX polled goats. Dev Dyn 224: 39-50 (2002).
    • (2002) Dev Dyn , vol.224 , pp. 39-50
    • Pailhoux, E.1    Vigier, B.2    Vaiman, D.3    Servel, N.4    Chaffaux, S.5
  • 57
    • 11444257032 scopus 로고    scopus 로고
    • Positional cloning of the PIS mutation in goats and its impact on understanding mammalian sex-differentiation
    • Pailhoux E, Vigier B, Schibler L, Cribiu EP, Cotinot C, Vaiman D: Positional cloning of the PIS mutation in goats and its impact on understanding mammalian sex-differentiation. Genet Sel Evol 37 Suppl 1: 55-64 (2005).
    • (2005) Genet Sel Evol , vol.37 , Issue.SUPPL. 1 , pp. 55-64
    • Pailhoux, E.1    Vigier, B.2    Schibler, L.3    Cribiu, E.P.4    Cotinot, C.5    Vaiman, D.6
  • 58
    • 0348077414 scopus 로고    scopus 로고
    • Expression studies of the PIS -regulated genes suggest different mechanisms of sex determination within mammals
    • Pannetier M, Servel N, Cocquet J, Besnard N, Cotinot C, Pailhoux E: Expression studies of the PIS -regulated genes suggest different mechanisms of sex determination within mammals. Cytogenet Genome Res 101: 199-205 (2003).
    • (2003) Cytogenet Genome Res , vol.101 , pp. 199-205
    • Pannetier, M.1    Servel, N.2    Cocquet, J.3    Besnard, N.4    Cotinot, C.5    Pailhoux, E.6
  • 59
    • 18844437228 scopus 로고    scopus 로고
    • Ovarian-specific expression of a new gene regulated by the goat PIS region and transcribed by a FOXL2 bidirectional promoter
    • Pannetier M, Renault L, Jolivet G, Cotinot C, Pailhoux E: Ovarian-specific expression of a new gene regulated by the goat PIS region and transcribed by a FOXL2 bidirectional promoter. Genomics 85: 715-726 (2005).
    • (2005) Genomics , vol.85 , pp. 715-726
    • Pannetier, M.1    Renault, L.2    Jolivet, G.3    Cotinot, C.4    Pailhoux, E.5
  • 60
    • 33745186041 scopus 로고    scopus 로고
    • FOXL2 activates P450 aromatase gene transcription: Towards a better characterization of the early steps of mammalian ovarian development
    • Pannetier M, Fabre S, Batista F, Kocer A, Renault L, et al: FOXL2 activates P450 aromatase gene transcription: towards a better characterization of the early steps of mammalian ovarian development. J Mol Endocrinol 36: 399-413 (2006).
    • (2006) J Mol Endocrinol , vol.36 , pp. 399-413
    • Pannetier, M.1    Fabre, S.2    Batista, F.3    Kocer, A.4    Renault, L.5
  • 61
    • 33750489078 scopus 로고    scopus 로고
    • R-spondin1 is essential in sex determination, skin differentiation and malignancy
    • Parma P, Radi O, Vidal V, Chaboissier MC, Dellambra E, et al: R-spondin1 is essential in sex determination, skin differentiation and malignancy. Nat Genet 38: 1304-1309 (2006).
    • (2006) Nat Genet , vol.38 , pp. 1304-1309
    • Parma, P.1    Radi, O.2    Vidal, V.3    Chaboissier, M.C.4    Dellambra, E.5
  • 62
    • 3042554114 scopus 로고    scopus 로고
    • Forkhead l2 is expressed in the ovary and represses the promoter activity of the steroidogenic acute regulatory gene
    • Pisarska MD, Bae J, Klein C, Hsueh AJ: Forkhead l2 is expressed in the ovary and represses the promoter activity of the steroidogenic acute regulatory gene. Endocrinology 145: 3424-3433 (2004).
    • (2004) Endocrinology , vol.145 , pp. 3424-3433
    • Pisarska, M.D.1    Bae, J.2    Klein, C.3    Hsueh, A.J.4
  • 63
    • 34547745384 scopus 로고    scopus 로고
    • Expression of putative sex-determining genes during the thermosensitive period of gonad development in the snapping turtle, Chelydra serpentina
    • Rhen T, Metzger K, Schroeder A, Woodward R: Expression of putative sex-determining genes during the thermosensitive period of gonad development in the snapping turtle, Chelydra serpentina. Sex Dev 1: 255-270 (2007).
    • (2007) Sex Dev , vol.1 , pp. 255-270
    • Rhen, T.1    Metzger, K.2    Schroeder, A.3    Woodward, R.4
  • 64
    • 4444294105 scopus 로고    scopus 로고
    • Fgf9 induces proliferation and nuclear localization of FGFR2 in Sertoli precursors during male sex determination
    • Schmahl J, Kim Y, Colvin JS, Ornitz DM, Capel B: Fgf9 induces proliferation and nuclear localization of FGFR2 in Sertoli precursors during male sex determination. Development 131: 3627-3636 (2004).
    • (2004) Development , vol.131 , pp. 3627-3636
    • Schmahl, J.1    Kim, Y.2    Colvin, J.S.3    Ornitz, D.M.4    Capel, B.5
  • 65
    • 1342327343 scopus 로고    scopus 로고
    • The murine winged-helix transcription factor Foxl2 is required for granulosa cell differentiation and ovary maintenance
    • Schmidt D, Ovitt CE, Anlag K, Fehsenfeld S, Gredsted L, et al: The murine winged-helix transcription factor Foxl2 is required for granulosa cell differentiation and ovary maintenance. Development 131: 933-942 (2004).
    • (2004) Development , vol.131 , pp. 933-942
    • Schmidt, D.1    Ovitt, C.E.2    Anlag, K.3    Fehsenfeld, S.4    Gredsted, L.5
  • 66
    • 45149093155 scopus 로고    scopus 로고
    • Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer
    • Sekido R, Lovell-Badge R: Sex determination involves synergistic action of SRY and SF1 on a specific Sox9 enhancer. Nature 453: 930-934 (2008).
    • (2008) Nature , vol.453 , pp. 930-934
    • Sekido, R.1    Lovell-Badge, R.2
  • 67
    • 63249135761 scopus 로고    scopus 로고
    • Association of reproductive performance with SNPs of Foxl2 gene by SSCP in Japanese flounder (Paralichthys olivaceus)
    • Shi B, Wen HS, He F, Dong SL, Ma S, et al: Association of reproductive performance with SNPs of Foxl2 gene by SSCP in Japanese flounder (Paralichthys olivaceus). Comp Biochem Physiol B Biochem Mol Biol 153: 1-7 (2009).
    • (2009) Comp Biochem Physiol B Biochem Mol Biol , vol.153 , pp. 1-7
    • Shi, B.1    Wen, H.S.2    He, F.3    Dong, S.L.4    Ma, S.5
  • 68
    • 77949863099 scopus 로고    scopus 로고
    • Genetic network underlying temperature-dependent sex determination is endogenously regulated by temperature in isolated cultured Trachemys scripta gonads
    • Shoemaker-Daly CM, Jackson K, Yatsu R, Matsumoto Y, Crews D: Genetic network underlying temperature-dependent sex determination is endogenously regulated by temperature in isolated cultured Trachemys scripta gonads. Dev Dyn 239: 1061-1075 (2010).
    • (2010) Dev Dyn , vol.239 , pp. 1061-1075
    • Shoemaker-Daly, C.M.1    Jackson, K.2    Yatsu, R.3    Matsumoto, Y.4    Crews, D.5
  • 69
    • 56449098100 scopus 로고    scopus 로고
    • Germ line control of female sex determination in zebrafish
    • Siegfried KR, Nüsslein-Volhard C: Germ line control of female sex determination in zebrafish. Dev Biol 324: 277-287 (2008).
    • (2008) Dev Biol , vol.324 , pp. 277-287
    • Siegfried, K.R.1    Nüsslein-Volhard, C.2
  • 70
    • 0025364886 scopus 로고
    • A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif
    • Sinclair AH, Berta P, Palmer MS, Hawkins JR, Griffiths BL, et al: A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif. Nature 346: 240-244 (1990).
    • (1990) Nature , vol.346 , pp. 240-244
    • Sinclair, A.H.1    Berta, P.2    Palmer, M.S.3    Hawkins, J.R.4    Griffiths, B.L.5
  • 71
    • 50249093862 scopus 로고    scopus 로고
    • Cloning and expression of R-spondin1 in different vertebrates suggests a conserved role in ovarian development
    • Smith CA, Shoemaker CM, Roeszler KN, Queen J, Crews D, Sinclair AH: Cloning and expression of R-spondin1 in different vertebrates suggests a conserved role in ovarian development. BMC Dev Biol 8: 72 (2008).
    • (2008) BMC Dev Biol , vol.8 , pp. 72
    • Smith, C.A.1    Shoemaker, C.M.2    Roeszler, K.N.3    Queen, J.4    Crews, D.5    Sinclair, A.H.6
  • 72
    • 42449158088 scopus 로고    scopus 로고
    • R-spondin1 plays an essential role in ovarian development through positively regulating Wnt-4 signaling
    • Tomizuka K, Horikoshi K, Kitada R, Sugawara Y, Iba Y, et al: R-spondin1 plays an essential role in ovarian development through positively regulating Wnt-4 signaling. Hum Mol Genet 17: 1278-1291 (2008).
    • (2008) Hum Mol Genet , vol.17 , pp. 1278-1291
    • Tomizuka, K.1    Horikoshi, K.2    Kitada, R.3    Sugawara, Y.4    Iba, Y.5
  • 73
    • 2942750361 scopus 로고    scopus 로고
    • Foxl2 disruption causes mouse ovarian failure by pervasive blockage of follicle development
    • Uda M, Ottolenghi C, Deiana M, Kimber W, Forabosco A, et al: Foxl2 disruption causes mouse ovarian failure by pervasive blockage of follicle development. Hum Mol Genet 13: 1171-1181 (2004).
    • (2004) Hum Mol Genet , vol.13 , pp. 1171-1181
    • Uda, M.1    Ottolenghi, C.2    Deiana, M.3    Kimber, W.4    Forabosco, A.5
  • 74
    • 71149095052 scopus 로고    scopus 로고
    • Somatic sex reprogramming of adult ovaries to testes by FOXL2 ablation
    • Uhlenhaut NH, Jakob S, Anlag K, Eisenberger T, Sekido R, et al: Somatic sex reprogramming of adult ovaries to testes by FOXL2 ablation. Cell 139: 1130-1142 (2009).
    • (2009) Cell , vol.139 , pp. 1130-1142
    • Uhlenhaut, N.H.1    Jakob, S.2    Anlag, K.3    Eisenberger, T.4    Sekido, R.5
  • 75
    • 0033521967 scopus 로고    scopus 로고
    • Female development in mammals is regulated by Wnt-4 signalling
    • Vainio S, Heikkilä M, Kispert A, Chin N, McMahon AP: Female development in mammals is regulated by Wnt-4 signalling. Nature 397: 405-409 (1999).
    • (1999) Nature , vol.397 , pp. 405-409
    • Vainio, S.1    Heikkilä, M.2    Kispert, A.3    Chin, N.4    McMahon, A.P.5
  • 76
    • 0037129827 scopus 로고    scopus 로고
    • Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
    • RESEARCH0034
    • Vandesompele J, De Preter K, Pattyn F, Poppe B, Van Roy N, et al: Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 3:RESEARCH0034 (2002).
    • (2002) Genome Biol , vol.3
    • Vandesompele, J.1    De Preter, K.2    Pattyn, F.3    Poppe, B.4    Van Roy, N.5
  • 78
    • 2942654592 scopus 로고    scopus 로고
    • Molecular cloning and gene expression of Foxl2 in the Nile tilapia, Oreochromis niloticus
    • Wang DS, Kobayashi T, Zhou LY, Nagahama Y: Molecular cloning and gene expression of Foxl2 in the Nile tilapia, Oreochromis niloticus. Biochem Biophys Res Commun 320: 83-89 (2004).
    • (2004) Biochem Biophys Res Commun , vol.320 , pp. 83-89
    • Wang, D.S.1    Kobayashi, T.2    Zhou, L.Y.3    Nagahama, Y.4
  • 79
    • 33847203240 scopus 로고    scopus 로고
    • Foxl2 up-regulates aromatase gene transcription in a female-specific manner by binding to the promoter as well as interacting with ad4 binding protein/steroidogenic factor 1
    • Wang DS, Kobayashi T, Zhou LY, Paul-Prasanth B, Ijiri S, et al: Foxl2 up-regulates aromatase gene transcription in a female-specific manner by binding to the promoter as well as interacting with ad4 binding protein/steroidogenic factor 1. Mol Endocrinol 21: 712-725 (2007).
    • (2007) Mol Endocrinol , vol.21 , pp. 712-725
    • Wang, D.S.1    Kobayashi, T.2    Zhou, L.Y.3    Paul-Prasanth, B.4    Ijiri, S.5
  • 80
    • 34447526784 scopus 로고    scopus 로고
    • R-spondin1 is a high affinity ligand for LRP6 and induces LRP6 phosphorylation and beta-catenin signaling
    • Wei Q, Yokota C, Semenov MV, Doble B, Woodgett J, He X: R-spondin1 is a high affinity ligand for LRP6 and induces LRP6 phosphorylation and beta-catenin signaling. J Biol Chem 282: 15903-15911 (2007).
    • (2007) J Biol Chem , vol.282 , pp. 15903-15911
    • Wei, Q.1    Yokota, C.2    Semenov, M.V.3    Doble, B.4    Woodgett, J.5    He, X.6
  • 81
    • 27744559963 scopus 로고    scopus 로고
    • Sertoli cell differentiation is induced both cell-autonomously and through prostaglandin signaling during mammalian sex determination
    • Wilhelm D, Martinson F, Bradford S, Wilson MJ, Combes AN, et al: Sertoli cell differentiation is induced both cell-autonomously and through prostaglandin signaling during mammalian sex determination. Dev Biol 287: 111-124 (2005).
    • (2005) Dev Biol , vol.287 , pp. 111-124
    • Wilhelm, D.1    Martinson, F.2    Bradford, S.3    Wilson, M.J.4    Combes, A.N.5
  • 82
    • 34249854973 scopus 로고    scopus 로고
    • SOX9 regulates prostaglandin D synthase gene transcription in vivo to ensure testis development
    • Wilhelm D, Hiramatsu R, Mizusaki H, Widjaja L, Combes AN, et al: SOX9 regulates prostaglandin D synthase gene transcription in vivo to ensure testis development. J Biol Chem 282: 10553-10560 (2007).
    • (2007) J Biol Chem , vol.282 , pp. 10553-10560
    • Wilhelm, D.1    Hiramatsu, R.2    Mizusaki, H.3    Widjaja, L.4    Combes, A.N.5
  • 83
    • 0001244671 scopus 로고
    • In situ hybridization
    • Oxford University Press, New York
    • Wilkinson DG: In situ hybridization. A practical approach. (Oxford University Press, New York 1992).
    • (1992) A Practical Approach
    • Wilkinson, D.G.1
  • 84
    • 34547651268 scopus 로고    scopus 로고
    • The developmental expression of foxl2 in the dogfish Scyliorhinus canicula
    • Wotton KR, French KE, Shimeld SM: The developmental expression of foxl2 in the dogfish Scyliorhinus canicula. Gene Expr Patterns 7: 793-797 (2007).
    • (2007) Gene Expr Patterns , vol.7 , pp. 793-797
    • Wotton, K.R.1    French, K.E.2    Shimeld, S.M.3
  • 85
    • 77953363039 scopus 로고    scopus 로고
    • Sex differentiation and sex change in the protandrous black porgy, Acanthopagrus schlegeli
    • Wu GC, Tomy S, Lee MF, Lee YH, Yueh WS, et al: Sex differentiation and sex change in the protandrous black porgy, Acanthopagrus schlegeli. Gen Comp Endocrinol 167: 417-421 (2010).
    • (2010) Gen Comp Endocrinol , vol.167 , pp. 417-421
    • Wu, G.C.1    Tomy, S.2    Lee, M.F.3    Lee, Y.H.4    Yueh, W.S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.