Ontogenesis of female-to-male sex-reversal in XX polled goats

Developmental Dynamics

Volumn 224, Issue 1, 2002, Pages 39-50

  Pailhoux, Eric ^a   Vigier, Bernard ^a   Vaiman, Daniel ^a   Servel, Nathalie ^a   Chaffaux, Stéphane ^a   Cribiu, Edmond P ^a   Cotinot, Corinne ^a  

^a CEMAGREF   (France)

Author keywords

PIS mutation; Polled goats; Sex determination; SOX9; XX sex reversal

Indexed keywords

AROMATASE;

ANIMAL EXPERIMENT; ARTICLE; CELL LINEAGE; CONTROLLED STUDY; GENE EXPRESSION; GENETIC MODEL; GOAT; GONAD DEVELOPMENT; IMMUNOHISTOCHEMISTRY; MALE; MUTATION; NONHUMAN; ONTOGENY; PHENOTYPE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEX DIFFERENTIATION; SEX TRANSFORMATION; XX MALE;

ANIMALS; FEMALE; GENITALIA; GENOTYPE; GLYCOPROTEINS; GOATS; GONADS; GROWTH INHIBITORS; HUMANS; MALE; PHENOTYPE; SEX DIFFERENTIATION; SEX REVERSAL, GONADAL; TESTICULAR HORMONES;

CAPRA HIRCUS; MAMMALIA;

EID: 0036234843     PISSN: 10588388     EISSN: None     Source Type: Journal    
DOI: 10.1002/dvdy.10083     Document Type: Article

References (55)

1. Amplification of the ZFY and ZFX genes for sex identification in humans, cattle, sheep and goats
2. Effects of aromatase inhibitor on sex differentiation and levels of P450 (17 alpha) and P450 arom messenger ribonucleic acid of gonads in chicken embryos
3. Targeted mutagenesis of the endogenous mouse Mis gene promoter: In vivo definition of genetic pathways of vertebrate sexual development
4. The genetic sex on intersexual goats and a probable linkage with the gene for hornlessness
5. Anatomic and cytogenetic studies on 19 hornless goats with sexual disorders
6. Abnormal sexual development in transgenic mice chronically expressing mullerian inhibiting substance
7. Sex-reversal and aromatase in the European pond turtle: Treatment with letrozole after the thermosensitive period for sex determination
8. Mesonephric contribution to testis differentiation in the fetal mouse
9. SRY-negative, XX intersex horses: The need for pedigree studies to examine the mode of inheritance of the condition
10. Migration of mesonephric cells into the mammalian gonad depends on Sry
11. Male-tofemale sex-reversal in mice lacking fibroblast growth factor 9
12. The putative forkhead transcription factor FOXL2 is mutated in blepharophimosis/ptosis/epicanthus inversus syndrome
13. Direct interaction of SRY-related protein SOX9 and steroidogenic factor 1 regulates transcription of the human anti-Mullerian hormone gene
14. Mus poschiavinus Y chromosome in the C57BL/6J murine genome causes sex-reversal
15. Campomelic dysplasia and autosomal sexreversal caused by mutations in an SRY-related gene
16. Ontogeny of expression of the genes for steroidogenic enzymes P450 side-chain cleavage, 3 beta-hydroxysteroid dehydrogenase, P450 17 alpha-hydroxylase/C17-20 lyase, and P450 aromatase in fetal mouse gonads
17. Germ cell loss in the XXY male mouse: Altered X-chromosome dosage affects prenatal development
18. Ontogeny of reproductive abnormalities induced by deregulation of anti-mullerian hormone expression in transgenic mice
19. Clinical and genetic variability in XX sex-reversed patients
20. Male-specific cell migration into the developing gonad
21. Sex determination and the Y chromosome
22. A minority of 46,XX true hermaphrodites are positive for the Y-DNA sequence including SRY
23. A regulatory cascade hypothesis for mammalian sex determination: SRY represses a negative regulator of male development
24. The fate of germ cells in the testis of fetal Sex-reversed mice
25. Sex-reversal in the mouse
26. X-chromosome activity in the germ cells of sex-reversed mouse embryos
27. XX sex-reversal in the American cocker spaniel dog: Phenotypic expression and inheritance
28. Mullerian-inhibiting substance secretion is delayed in XX sex-reversed dog embryos
29. Sry-negative XX sex-reversal in purebred dogs
30. Sox9 expression during gonadal development implies a conserved role for the gene in testis differentiation in mammals and birds
31. Molecular analysis of 60,XX pseudohermaphrodite polled goats for the presence of SRY and ZFY genes
32. Relevance of intersexuality to breeding and reproductive biotechnology programs, XX sex-reversal in pigs
33. A 11.7 kb deletion triggers intersexuality and polledness in goats
34. Characterization of ovine SRY transcript and developmental expression of genes involved in sexual differentiation
35. An abnormal terminal X-Y interchange accounts for most but not all cases of human XX maleness
36. Ontogeny of steroidogenesis in the fetal sheep gonad
37. Effect of anti-Mullerian hormone on Sertoli and Leydig cell functions in fetal and immature rats
38. Fine mapping suggests that polled intersex syndrome and the human Blepharophimosis Ptosis Epicanthus syndrome map to a 100-kb homologous region
39. Sry induces cell proliferation in the mouse gonad
40. Human sex determination
41. A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motif
42. Familial 46,XX males coexisting with familial 46,XX true hermaphrodites in same pedigree
43. Cytogenetics of Saanen goats showing abnormal development of the reproductive tract associated with the dominant gene for polledness
44. Targeted disruption of the aromatase P450 (Cyp19) in mice and their ovarian and uterine responses to 17β-oestradiol
45. Expression of AMH, SF1, and SOX9 in gonads of genetic female chickens during sex reversal induced by an aromatase inhibitor
46. Mammalian sex reversal and intersexuality: Deciphering the sex-determination cascade
47. Genetic mapping of the autosomal region involved in XX sex-reversal and horn development in goats
48. The gonads of human true hermaphrodites
49. Testis determination in mammals: More questions than answers
50. Sox9 induces testis development in XX transgenic mice
51. Origin of anti-Mullerian hormone in bovine freemartin fetuses
52. Secretion of anti-Mullerian hormone by immature bovine Sertoli cells in primary culture, studied by a competition-type radioimmunoassay: Lack of modulation by either FSH or testosterone
53. Purified bovine AMH induces a characteristic freemartin effect in fetal rat prospective ovaries exposed to it in vitro
54. Anti-Mullerian hormone produces endocrine sex-reversal of fetal ovaries
55. Autosomal sex-reversal and campomelic dysplasia are caused by mutations in and around the SRY-related gene SOX9