Cathepsin D is released after severe tissue trauma in vivo and is capable of generating C5a in vitro

Molecular Immunology

Volumn 50, Issue 1-2, 2012, Pages 60-65

  Huber Lang, Markus ^a   Denk, Stephanie ^a   Fulda, Simone ^b   Erler, Ellen ^a   Kalbitz, Miriam ^a   Weckbach, Sebastian ^a   Schneider, E Marion ^a   Weiss, Manfred ^a   Kanse, Sandip M ^c   Perl, Mario ^a  

^a UNIVERSITY HOSPITAL ULM   (Germany)

^b GOETHE UNIVERSITY   (Germany)

^c JUSTUS LIEBIG UNIVERSITY   (Germany)

Author keywords

Apoptosis; C5a; Cathepsin d; Complement; Polytrauma

Indexed keywords

CATHEPSIN D; COMPLEMENT COMPONENT C5A; PEPSTATIN;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IN VITRO STUDY; IN VIVO STUDY; NEUTROPHIL; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN INTERACTION; PROTEIN SECRETION; SEQUENCE ANALYSIS; TISSUE INJURY;

BIOCATALYSIS; BLOTTING, WESTERN; CATHEPSIN D; CHEMOTAXIS, LEUKOCYTE; COMPLEMENT ACTIVATION; COMPLEMENT C5; COMPLEMENT C5A; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; NEUTROPHILS; PEPSTATINS; PROTEASE INHIBITORS; TIME FACTORS; WOUNDS AND INJURIES;

EID: 84857041124     PISSN: 01615890     EISSN: 18729142     Source Type: Journal    
DOI: 10.1016/j.molimm.2011.12.005     Document Type: Article

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