C/EBPβ and RUNX2 cooperate to degrade cartilage with MMP-13 as the target and HIF-2α as the inducer in chondrocytes

Human Molecular Genetics

Volumn 21, Issue 5, 2012, Pages 1111-1123

  Hirata, Makoto ^a   Kugimiya, Fumitaka ^a   Fukai, Atsushi ^a   Saito, Taku ^a   Yano, Fumiko ^a   Ikeda, Toshiyuki ^a   Mabuchi, Akihiko ^a   Sapkota, Bishwa Raj ^a   Akune, Toru ^a   Nishida, Nao ^a   Yoshimura, Noriko ^a   Nakagawa, Takumi ^a   Tokunaga, Katsushi ^a   Nakamura, Kozo ^a   Chung, Ung il ^a   Kawaguchi, Hiroshi ^a  

^a UNIVERSITY OF TOKYO   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN BETA; CIS ACTING ELEMENT; CIS ACTING ELEMENT 2; COLLAGENASE 3; HYPOXIA INDUCIBLE FACTOR 2ALPHA; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG;

ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE GROWTH; CARTILAGE CELL; CARTILAGE DEGENERATION; CELL DIFFERENTIATION; CONTROLLED STUDY; EMBRYO; ENCHONDRAL OSSIFICATION; FEMALE; GENE CONTROL; GENE FREQUENCY; GENE TARGETING; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; GROWTH RETARDATION; HUMAN; KNEE ARTHROPLASTY; KNEE OSTEOARTHRITIS; KNOCKOUT MOUSE; MAJOR CLINICAL STUDY; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OSTEOBLAST; PREDICTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; REPORTER GENE; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM;

AGED; AGED, 80 AND OVER; ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BONE DEVELOPMENT; CARTILAGE; CCAAT-ENHANCER-BINDING PROTEIN-BETA; CELL LINE, TUMOR; CELLS, CULTURED; CHONDROCYTES; CORE BINDING FACTOR ALPHA 1 SUBUNIT; HUMANS; MATRIX METALLOPROTEINASE 13; MICE; MIDDLE AGED; OSTEOARTHRITIS; OSTEOARTHRITIS, KNEE; PROMOTER REGIONS, GENETIC; TRANSCRIPTION, GENETIC; TRANSCRIPTIONAL ACTIVATION;

EID: 84856971211     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddr540     Document Type: Article

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