Cocaine-induced kidney toxicity: An in vitro study using primary cultured human proximal tubular epithelial cells

Archives of Toxicology

Volumn 86, Issue 2, 2012, Pages 249-261

  Valente, Maria João ^a   Henrique, Rui ^a,b   Vilas Boas, Vânia ^a   Silva, Renata ^a   Bastos, Maria De Lourdes ^a   Carvalho, Félix ^a   Guedes De Pinho, Paula ^a   Carvalho, Márcia ^a,c  

^a UNIVERSITY OF PORTO   (Portugal)

^b PORTUGUESE ONCOLOGY INSTITUTE   (Portugal)

^c UNIVERSIDADE FERNANDO PESSOA   (Portugal)

Author keywords

Apoptosis; Cocaine; Human renal proximal tubular cells; Metabolism; Nephrotoxicity

Indexed keywords

BENZOYLECGONINE; COCAINE; ECGONINE METHYL ESTER; GLUTATHIONE; KETOCONAZOLE; NORCOCAINE;

APOPTOSIS; ARTICLE; CELL DEATH; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; EPITHELIUM CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; ION TRAP MASS SPECTROMETRY; KIDNEY CELL CULTURE; KIDNEY PROXIMAL TUBULE; KIDNEY TUBULE CELL; MASS FRAGMENTOGRAPHY; METABOLITE; NEPHROTOXICITY; PRIORITY JOURNAL;

ADENOSINE TRIPHOSPHATE; ANESTHETICS, LOCAL; APOPTOSIS; CELLS, CULTURED; COCAINE; CYTOCHROME P-450 CYP3A; EPITHELIAL CELLS; GLUTATHIONE; HUMANS; KIDNEY TUBULES, PROXIMAL; RENAL INSUFFICIENCY;

EID: 84856951491     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-011-0749-3     Document Type: Article

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