Role of mitochondrial cytochrome c in cocaine-induced apoptosis in coronary artery endothelial cells

Journal of Pharmacology and Experimental Therapeutics

Volumn 295, Issue 3, 2000, Pages 896-903

  He, Jiale ^a   Xiao, Yuhui ^a   Casiano, Carlos A ^a   Zhang, Lubo ^a  

^a LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 8; CASPASE 9; COCAINE; CYTOCHROME C; MITOCHONDRIAL ENZYME; PROTEIN BAX; PROTEIN BCL 2;

ANIMAL CELL; APOPTOSIS; ARTICLE; CATTLE; COCAINE DEPENDENCE; CONTROLLED STUDY; CORONARY ARTERY; ENDOTHELIUM CELL; ENZYME RELEASE; HEART MUSCLE ISCHEMIA; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASES; CATTLE; CELLS, CULTURED; COCAINE; CORONARY VESSELS; CYTOCHROME C GROUP; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIUM, VASCULAR; MITOCHONDRIA; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 0033695354     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. The Bcl-2 protein family: Arbiters of cell survival
2. Death receptors: Signaling and modulation
3. Clinical pharmacology and toxicology of cocaine
4. Surface blebs on apoptotic cells are sites of enhanced procoagulant activity: Implication for coagulation events and antigenic spread in systemic lupus erythematosus
5. Regulation of bcl-2 family proteins during development and in response to oxidative stress in cardiac myocytes: Association with changes in mitochondrial membrane potential
6. Suppression of apoptosis by nitric oxide via inhibition of interleukin-1beta-converting enzyme (ICE)-like and cysteine protease protein (CPP)-32-like proteases
7. Direct embryo-toxicity of cocaine in rats: Effects on mitochondrial activity, cardiac function, and growth and development in vitro
8. Mechanism of cocaine-induced myocardial depression in dogs
9. Mitochondria and apoptosis
10. Oxidized low density lipoprotein induces apoptosis in cultured human umbilical vein endothelial cells by common and unique mechanisms
11. Apoptosis: Basic mechanisms and implications for cardiovascular disease
12. Cocaine induces apoptosis in human coronary artery endothelial cells
13. Modulation of cytokine-induced cardiac myocyte apoptosis by nitric oxide, Bak, and Bcl-x
14. Cocaine and metabolite concentrations in plasma during repeated oral administration: Development of a human laboratory model of chronic cocaine use
15. Bax directly induces release of cytochrome c from isolated mitochondria
16. Nitric oxide as a bifunctional regulator of apoptosis
17. Nitric oxide suppression of apoptosis occurs in association with an inhibition of Bcl-2 cleavage and cytochrome c release
18. The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
19. Bcl-2 and Bax expression in adult rat hearts after coronary occlusion: Age-associated differences
20. Death by design: Programmed cell death in cardiovascular biology and disease
21. Fas-induced caspase denitrosylation
22. Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis
23. Bcl-2 inhibits bax translocation from cytosol to mitochondria during drug-induced apoptosis of human tumor cells
24. Bcl-2 inhibits a Fas-induced conformational change in the Bax N-terminus and Bax mitochondrial translocation
25. Cocaine induces apoptosis in cortical neurons of fetal mice
26. Apoptotic cytosol facilitates Bax translocation to mitochondria that involves cytosolic factor regulated by Bcl-2
27. Bcl-2 prolongs cell survival after Bax-induced release of cytochrome c
28. Acute intravenous cocaine causes transient depression followed by enhanced left ventricular function in conscious dogs
29. Caspases: Enemies within
30. Cyclosporin A inhibits apoptosis of human endothelial cells by preventing release of cytochrome c from mitochondria
31. Regulation of cardiomyocyte apoptotic signaling by insulin-like growth factor I
32. Cocaine induces apoptosis in fetal myocardial cells: Role of mitochondria
33. Maternal administration of cocaine induces apoptosis in fetal heart: Role of Bax and Bcl-2
34. Cocaine induces apoptosis in fetal rat brain by up-regulation of Bax/Bcl-2
35. Prevention of apoptosis by Bcl-2: Release of cytochrome c from mitochondria blocked
36. Cocaine-induced mitochondrial dysfunction in primary cultures of rat cardiomyocytes
37. An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9