-
1
-
-
58049211966
-
Mechanotransduction at a distance: Mechanically coupling the extracellular matrix with the nucleus
-
Wang N, Tytell JD, Ingber DE (2009) Mechanotransduction at a distance: Mechanically coupling the extracellular matrix with the nucleus. Nat. Rev. Mol. Cell Biol. 10:75-82
-
(2009)
Nat. Rev. Mol. Cell Biol
, vol.10
, pp. 75-82
-
-
Wang, N.1
Tytell, J.D.2
Ingber, D.E.3
-
4
-
-
27944497333
-
Tissue cells feel and respond to the stiffness of their substrate
-
Discher DE, Janmey P, Wang YL (2005) Tissue cells feel and respond to the stiffness of their substrate. Science 310:1139-1143
-
(2005)
Science
, vol.310
, pp. 1139-1143
-
-
Discher, D.E.1
Janmey, P.2
Wang, Y.L.3
-
5
-
-
61349168351
-
A mechanosensitive transcriptional mechanism that controls angiogenesis
-
Mammoto A, Connor KM, Mammoto T, Yung CW, Huh D, Aderman CM, Mostoslavsky G, Smith LE, Ingber DE (2009) A mechanosensitive transcriptional mechanism that controls angiogenesis. Nature 457:1103-1108
-
(2009)
Nature
, vol.457
, pp. 1103-1108
-
-
Mammoto, A.1
Connor, K.M.2
Mammoto, T.3
Yung, C.W.4
Huh, D.5
Aderman, C.M.6
Mostoslavsky, G.7
Smith, L.E.8
Ingber, D.E.9
-
6
-
-
0030953763
-
Geometric control of cell life and death
-
Chen CS, Mrksich M, Huang S, Whitesides GM, Ingber DE (1997) Geometric control of cell life and death. Science 276(5317):1425-1428
-
(1997)
Science
, vol.276
, Issue.5317
, pp. 1425-1428
-
-
Chen, C.S.1
Mrksich, M.2
Huang, S.3
Whitesides, G.M.4
Ingber, D.E.5
-
8
-
-
0031421084
-
Topographical control of cells
-
Curtis A, Wilkinson C (1997) Topographical control of cells. Biomaterials 18:1573-1583
-
(1997)
Biomaterials
, vol.18
, pp. 1573-1583
-
-
Curtis, A.1
Wilkinson, C.2
-
9
-
-
0033696170
-
Substrate flexibility regulates growth and apoptosis of normal but not transformed cells
-
Wang HB, Dembo M, Wang YL (2000) Substrate flexibility regulates growth and apoptosis of normal but not transformed cells. Am. J. Physiol. 279:C1345-C1350
-
(2000)
Am. J. Physiol
, vol.279
-
-
Wang, H.B.1
Dembo, M.2
Wang, Y.L.3
-
10
-
-
33747152561
-
Matrix elasticity directs stem cell lineage specification
-
Engler AJ, Sen S, Sweeney HL, Discher DE (2006) Matrix elasticity directs stem cell lineage specification. Cell 126:677-689
-
(2006)
Cell
, vol.126
, pp. 677-689
-
-
Engler, A.J.1
Sen, S.2
Sweeney, H.L.3
Discher, D.E.4
-
11
-
-
0031904354
-
Osteoblasts induce osteopontin expression in response to attachment on fibronectin: Demonstration of a common role for integrin receptors in the signal transduction processes of cell attachment and mechanical stimulation
-
Carvalho RS, Schaffer JL, Gerstenfeld LC (1998) Osteoblasts induce osteopontin expression in response to attachment on fibronectin: Demonstration of a common role for integrin receptors in the signal transduction processes of cell attachment and mechanical stimulation, J. Cell. Biochem. 70:376-390
-
(1998)
J. Cell. Biochem
, vol.70
, pp. 376-390
-
-
Carvalho, R.S.1
Schaffer, J.L.2
Gerstenfeld, L.C.3
-
12
-
-
0021069981
-
Fibronectin modulation of cell shape and lipogenic gene expression in 3T3-Adipocytes
-
Spiegelman BM, Ginty GA (1983) Fibronectin modulation of cell shape and lipogenic gene expression in 3T3-Adipocytes. Cell 35:657-666
-
(1983)
Cell
, vol.35
, pp. 657-666
-
-
Spiegelman, B.M.1
Ginty, G.A.2
-
13
-
-
1842426730
-
Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment
-
McBeath R, Pirone DM, Nelson CM, Bhadriraju K, Chen CS (2004) Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment. Dev. Cell 6:483-495
-
(2004)
Dev. Cell
, vol.6
, pp. 483-495
-
-
McBeath, R.1
Pirone, D.M.2
Nelson, C.M.3
Bhadriraju, K.4
Chen, C.S.5
-
14
-
-
0033917881
-
Cell movement is guided by the rigidity of the substrates
-
Lo CM, Wang HB, Dembo M, Wang, YL (2000) Cell movement is guided by the rigidity of the substrates. Biophys. J. 79:144-152
-
(2000)
Biophys. J.
, vol.79
, pp. 144-152
-
-
Lo, C.M.1
Wang, H.B.2
Dembo, M.3
Wang, Y.L.4
-
15
-
-
0033595232
-
Regulation of cell movement is mediated by stretch-Activated calcium channels
-
Lee J, Ishihara A, Oxford G, Johnson B, Jacobson K (1999) Regulation of cell movement is mediated by stretch-Activated calcium channels. Nature 400:382-386
-
(1999)
Nature
, vol.400
, pp. 382-386
-
-
Lee, J.1
Ishihara, A.2
Oxford, G.3
Johnson, B.4
Jacobson, K.5
-
16
-
-
0026753554
-
Calcium imaging of mechanically induced fluxes in tissue cultured chick heart: Role of stretch activated ion channels
-
Sigurdson W, Ruknudin A, Sachs F (1992) Calcium imaging of mechanically induced fluxes in tissue cultured chick heart: Role of stretch activated ion channels. Am. J. Physiol. Heart Circ. Physiol. 262:H1110-H1115
-
(1992)
Am. J. Physiol. Heart Circ. Physiol
, vol.262
-
-
Sigurdson, W.1
Ruknudin, A.2
Sachs, F.3
-
17
-
-
0346656873
-
Regulation of mechanical interaction between fibroblasts and the substratum by stretch activated Ca2+ entry
-
Munevar S, Wang YL, Dembo M (2004) Regulation of mechanical interaction between fibroblasts and the substratum by stretch activated Ca2+ entry. J. Cell Sci. 117:85-92
-
(2004)
J. Cell Sci
, vol.117
, pp. 85-92
-
-
Munevar, S.1
Wang, Y.L.2
Dembo, M.3
-
19
-
-
2342472716
-
Focal adhesion and actin dynamics: A place where kinases and proteases meet to promote invasion
-
Carragher NO, Frame MC (2004) Focal adhesion and actin dynamics: A place where kinases and proteases meet to promote invasion. Trends Cell Biol. 14:24-249
-
(2004)
Trends Cell Biol
, vol.14
, pp. 24-249
-
-
Carragher, N.O.1
Frame, M.C.2
-
20
-
-
4444285115
-
Mechanotransduction at cell-matrix and cell-cell contacts
-
Chen CS, Tan J, Tien J (2004) Mechanotransduction at cell-matrix and cell-cell contacts. Annu. Rev. Biomed. Eng. 6:275-302
-
(2004)
Annu. Rev. Biomed. Eng
, vol.6
, pp. 275-302
-
-
Chen, C.S.1
Tan, J.2
Tien, J.3
-
21
-
-
0035844869
-
Focal contacts as mechanosensors: Externally applied local mechanical force induces growth of focal contacts by an mDia1-Dependent and ROCK-independent mechanism
-
Riveline D, Zamir E, Balaban NQ, Schwarz US, Ishizaki T, Narumiya S, Kam Z, Geiger B, Bershadsky AD (2001) Focal contacts as mechanosensors: Externally applied local mechanical force induces growth of focal contacts by an mDia1-Dependent and ROCK-independent mechanism. J. Cell Biol. 153:1175-1186
-
(2001)
J. Cell Biol
, vol.153
, pp. 1175-1186
-
-
Riveline, D.1
Zamir, E.2
Balaban, N.Q.3
Schwarz, U.S.4
Ishizaki, T.5
Narumiya, S.6
Kam, Z.7
Geiger, B.8
Bershadsky, A.D.9
-
22
-
-
0027172919
-
Mechanotransduction across the cell surface and through the cytoskeleton
-
Wang N, Butler JP, Ingber DE (1993) Mechanotransduction across the cell surface and through the cytoskeleton. Science 260:1124-1127
-
(1993)
Science
, vol.260
, pp. 1124-1127
-
-
Wang, N.1
Butler, J.P.2
Ingber, D.E.3
-
23
-
-
0030994017
-
Extracellular matrix rigidity causes strengthening of integrin-cytoskeleton linkages
-
Choquet D, Felsenfeld DP, Sheetz MP (1997) Extracellular matrix rigidity causes strengthening of integrin-cytoskeleton linkages. Cell 88:39-48
-
(1997)
Cell
, vol.88
, pp. 39-48
-
-
Choquet, D.1
Felsenfeld, D.P.2
Sheetz, M.P.3
-
24
-
-
1842530398
-
Integrins in mechanotransduction
-
Katsumi A et al (2004) Integrins in mechanotransduction. J. Biol. Chem. 279:12001-12004
-
(2004)
J. Biol. Chem
, vol.279
, pp. 12001-12004
-
-
Katsumi, A.1
-
25
-
-
0032079456
-
Force required to break a5b1 integrin-fibronectin bonds in intact adherent cells is sensitive to integrin activation state
-
Garcia AJ, Huber F, Boettiger D (1998) Force required to break a5b1 integrin-fibronectin bonds in intact adherent cells is sensitive to integrin activation state. J. Biol. Chem. 273 (18):10988-10993
-
(1998)
J. Biol. Chem
, vol.273
, Issue.18
, pp. 10988-10993
-
-
Garcia, A.J.1
Huber, F.2
Boettiger, D.3
-
26
-
-
74549222971
-
Integrin clustering is driven by mechanical resistance from the glycocalyx and the substrate
-
Paszek MJ, Boettiger D, Weaver VM, Hammer DA (2009) Integrin clustering is driven by mechanical resistance from the glycocalyx and the substrate. PLoS Comput. Biol. 5:1-16
-
(2009)
PLoS Comput. Biol
, vol.5
, pp. 1-16
-
-
Paszek, M.J.1
Boettiger, D.2
Weaver, V.M.3
Hammer, D.A.4
-
27
-
-
0035949694
-
Focal adhesion kinase is involved in mechanosensing during fibroblast migration
-
Wang HB, Dembo M, Wang YL (2001) Focal adhesion kinase is involved in mechanosensing during fibroblast migration. Proc. Natl. Acad. Sci. U.S.A. 98:11295-11300
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 11295-11300
-
-
Wang, H.B.1
Dembo, M.2
Wang, Y.L.3
-
28
-
-
17844388845
-
Visualizing the mechanical activation of Src
-
Wang Y et al (2005) Visualizing the mechanical activation of Src. Nature 434:1040-1045
-
(2005)
Nature
, vol.434
, pp. 1040-1045
-
-
Wang, Y.1
-
29
-
-
0028836195
-
F-Actin binding site masked by the intramolecular association of vinculin head and tail domains
-
Johnson RP, Craig SW (1995) F-Actin binding site masked by the intramolecular association of vinculin head and tail domains. Nature 373:261-264
-
(1995)
Nature
, vol.373
, pp. 261-264
-
-
Johnson, R.P.1
Craig, S.W.2
-
30
-
-
33751335857
-
Force sensing by mechanical extension of the Src family kinase substrate p130Cas
-
Sawada Y et al (2006) Force sensing by mechanical extension of the Src family kinase substrate p130Cas. Cell 127:1015-1026
-
(2006)
Cell
, vol.127
, pp. 1015-1026
-
-
Sawada, Y.1
-
31
-
-
35848967591
-
Retrograde fluxes of focal adhesion proteins in response to cell migration and mechanical signals
-
Guo WH, Wang YL (2007) Retrograde fluxes of focal adhesion proteins in response to cell migration and mechanical signals. Mol. Biol. Cell 18:4519-4527
-
(2007)
Mol. Biol. Cell
, vol.18
, pp. 4519-4527
-
-
Guo, W.H.1
Wang, Y.L.2
-
32
-
-
0032823984
-
Orientation of chemotactic cells and growth cones: Models and mechanisms
-
Meinhardt H (1999) Orientation of chemotactic cells and growth cones: Models and mechanisms. J. Cell Sci. 112:2867-2874
-
(1999)
J. Cell Sci
, vol.112
, pp. 2867-2874
-
-
Meinhardt, H.1
-
33
-
-
0036708448
-
Establishing direction during chemotaxis in eukaryotic cells
-
Rappel WJ, Thomas PJ, Levine H, Loomis WF (2002) Establishing direction during chemotaxis in eukaryotic cells. Biophys. J. 83:1361-1367
-
(2002)
Biophys. J.
, vol.83
, pp. 1361-1367
-
-
Rappel, W.J.1
Thomas, P.J.2
Levine, H.3
Loomis, W.F.4
-
36
-
-
0032550177
-
Rho-mediated contractility exposes a cryptic site in fibronectin and induces fibronectin matrix assembly
-
Zhong CL, Chrzanowska-Wodnicka M, Brown J, Shaub A, Belkin AM, Burridge K (1998) Rho-mediated contractility exposes a cryptic site in fibronectin and induces fibronectin matrix assembly. J. Cell Biol. 141:539-551
-
(1998)
J. Cell Biol
, vol.141
, pp. 539-551
-
-
Zhong, C.L.1
Chrzanowska-Wodnicka, M.2
Brown, J.3
Shaub, A.4
Belkin, A.M.5
Burridge, K.6
-
37
-
-
0037117522
-
Fibronectin extension and unfolding within cell matrix fibrils controlled by cytoskeletal tension
-
Baneyx G, Baugh L, Vogel V (2002) Fibronectin extension and unfolding within cell matrix fibrils controlled by cytoskeletal tension. Proc. Natl. Acad. Sci. U.S.A. 99:5139-5143
-
(2002)
Proc. Natl. Acad. Sci. U.S.A.
, vol.99
, pp. 5139-5143
-
-
Baneyx, G.1
Baugh, L.2
Vogel, V.3
-
39
-
-
28444491145
-
Is the mechanical activity of epithelial cells controlled by deformations or forces
-
Saez A, Buguin A, Silberzan P, Ladoux B (2005) Is the mechanical activity of epithelial cells controlled by deformations or forces? Biophys. J. 89:L52-L54
-
(2005)
Biophys. J.
, vol.89
-
-
Saez, A.1
Buguin, A.2
Silberzan, P.3
Ladoux, B.4
-
40
-
-
0344912596
-
Cell locomotion and focal adhesions are regulated by substrate flexibility
-
Pelham RJ Jr., Wang YL (1997) Cell locomotion and focal adhesions are regulated by substrate flexibility. Proc. Natl. Acad. Sci. U.S.A. 94:13661-13665
-
(1997)
Proc. Natl. Acad. Sci. U.S.A.
, vol.94
, pp. 13661-13665
-
-
Pelham Jr., R.J.1
Wang, Y.L.2
-
42
-
-
0345381774
-
Endothelial cell traction forces on RGDderivatized polyacrylamide substrata
-
Reinhart-King CA, Dembo M, Hammer DA (2003) Endothelial cell traction forces on RGDderivatized polyacrylamide substrata. Langmuir 19:1573-1579
-
(2003)
Langmuir
, vol.19
, pp. 1573-1579
-
-
Reinhart-King, C.A.1
Dembo, M.2
Hammer, D.A.3
-
43
-
-
0034834329
-
Fibronectin, integrins, and growth control
-
Danen EHJ, Yamada KM (2001) Fibronectin, integrins, and growth control. J. Cell Physiol. 189:1-13
-
(2001)
J. Cell Physiol
, vol.189
, pp. 1-13
-
-
Danen, E.H.J.1
Yamada, K.M.2
-
44
-
-
0030661566
-
Integrins, oncogenes, and anchorage independence
-
Schwartz MA (1997) Integrins, oncogenes, and anchorage independence. J. Cell Biol. 139:575-578
-
(1997)
J. Cell Biol
, vol.139
, pp. 575-578
-
-
Schwartz, M.A.1
-
45
-
-
22944454223
-
The tension mounts: Mechanics meets morphogenesis and malignancy
-
Paszek MJ, Weaver VM (2004) The tension mounts: Mechanics meets morphogenesis and malignancy. J. Mammary Gland Biol. Neoplasia 9:325-342
-
(2004)
J. Mammary Gland Biol. Neoplasia
, vol.9
, pp. 325-342
-
-
Paszek, M.J.1
Weaver, V.M.2
-
46
-
-
33847036735
-
Soft biological materials and their impact on cell function
-
Levental I, Georges PC, Janmey PA (2007) Soft biological materials and their impact on cell function. Soft Matter 3:299-306
-
(2007)
Soft Matter
, vol.3
, pp. 299-306
-
-
Levental, I.1
Georges, P.C.2
Janmey, P.A.3
-
47
-
-
24944436269
-
Cell tension, matrix mechanics, and cancer development
-
Huang S, Ingber DE (2005) Cell tension, matrix mechanics, and cancer development. Cancer Cell 8:175-176
-
(2005)
Cancer Cell
, vol.8
, pp. 175-176
-
-
Huang, S.1
Ingber, D.E.2
-
48
-
-
24944547482
-
Tensional homeostasis and the malignant phenotype
-
Paszek MJ, Zahir N, Johnson KR, Lakins JN, Rozenberg GI, Gefen A, Reinhart-King CA, Margulies SS, Dembo M, Boettiger D, Hammer DA, Weaver VM (2005) Tensional homeostasis and the malignant phenotype. Cancer Cell 8:241-254
-
(2005)
Cancer Cell
, vol.8
, pp. 241-254
-
-
Paszek, M.J.1
Zahir, N.2
Johnson, K.R.3
Lakins, J.N.4
Rozenberg, G.I.5
Gefen, A.6
Reinhart-King, C.A.7
Margulies, S.S.8
Dembo, M.9
Boettiger, D.10
Hammer, D.A.11
Weaver, V.M.12
-
49
-
-
70450222098
-
Matrix crosslinking forces tumor progression by enhancing integrin signaling
-
Levental KR, Yu H, Kass L, Lakins JN, Egeblad M, Erler JT, Fong SF, Csiszar K, Giaccia A, Weninger W, Yamauchi M, Gasser DL, Weaver VM (2009) Matrix crosslinking forces tumor progression by enhancing integrin signaling. Cell 139:891-906
-
(2009)
Cell
, vol.139
, pp. 891-906
-
-
Levental, K.R.1
Yu, H.2
Kass, L.3
Lakins, J.N.4
Egeblad, M.5
Erler, J.T.6
Fong, S.F.7
Csiszar, K.8
Giaccia, A.9
Weninger, W.10
Yamauchi, M.11
Gasser, D.L.12
Weaver, V.M.13
-
50
-
-
18844428327
-
Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion
-
Orimo A, Gupta PB, Sgroi DC, Arenzana-Seisdedos F, Delaunay T, Naeem R, Carey VJ, Richardson AL, Weinberg RA (2005) Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell 121:335-348
-
(2005)
Cell
, vol.121
, pp. 335-348
-
-
Orimo, A.1
Gupta, P.B.2
Sgroi, D.C.3
Arenzana-Seisdedos, F.4
Delaunay, T.5
Naeem, R.6
Carey, V.J.7
Richardson, A.L.8
Weinberg, R.A.9
-
51
-
-
33646005836
-
Substrate rigidity regulates the formation and maintenance of tissues
-
Guo WH, Frey MT, Burnham NA, Wang YL (2006) Substrate rigidity regulates the formation and maintenance of tissues. Biophys. J. 90:2213-2220
-
(2006)
Biophys. J.
, vol.90
, pp. 2213-2220
-
-
Guo, W.H.1
Frey, M.T.2
Burnham, N.A.3
Wang, Y.L.4
-
52
-
-
0035189927
-
Embryo-Derived stem cells: Of mice and men
-
Smith AG (2001) Embryo-Derived stem cells: Of mice and men. Annu. Rev. Cell Dev. Biol. 17:435-462
-
(2001)
Annu. Rev. Cell Dev. Biol
, vol.17
, pp. 435-462
-
-
Smith, A.G.1
|